Details for: UBE2K
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 492.4934
Cell Significance Index: -76.6100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 319.2277
Cell Significance Index: -80.9700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 207.5871
Cell Significance Index: -85.5200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 188.0761
Cell Significance Index: -88.8000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 181.4860
Cell Significance Index: -73.7300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 164.0405
Cell Significance Index: -84.3800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 133.0657
Cell Significance Index: -89.2900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 77.6125
Cell Significance Index: -74.1000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 68.1330
Cell Significance Index: -84.0100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 30.2965
Cell Significance Index: -81.1600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 26.0691
Cell Significance Index: -80.0700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 24.0840
Cell Significance Index: -52.7100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 22.4402
Cell Significance Index: -88.5500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 5.0233
Cell Significance Index: 134.1300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.2385
Cell Significance Index: 642.7000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.9357
Cell Significance Index: 75.4600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.4567
Cell Significance Index: 492.8200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.0723
Cell Significance Index: 743.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.0089
Cell Significance Index: 112.7300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.9120
Cell Significance Index: 146.7300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.8986
Cell Significance Index: 53.0600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.8065
Cell Significance Index: 325.6600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.7976
Cell Significance Index: 195.5300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.7607
Cell Significance Index: 216.5000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.1355
Cell Significance Index: 51.4700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.1268
Cell Significance Index: 69.2600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.9977
Cell Significance Index: 690.0400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.9288
Cell Significance Index: 507.2200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.8361
Cell Significance Index: 369.6800 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.8218
Cell Significance Index: 16.0400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7190
Cell Significance Index: 20.7200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.6679
Cell Significance Index: 44.9100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.6295
Cell Significance Index: 29.5900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.6183
Cell Significance Index: 28.8300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.5855
Cell Significance Index: 80.4000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4194
Cell Significance Index: 18.5500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4054
Cell Significance Index: 21.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3679
Cell Significance Index: 692.7900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3110
Cell Significance Index: 11.7800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2678
Cell Significance Index: 13.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2525
Cell Significance Index: 18.8200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2382
Cell Significance Index: 108.1100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2152
Cell Significance Index: 331.2600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2137
Cell Significance Index: 135.6900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2120
Cell Significance Index: 34.4800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2031
Cell Significance Index: 374.5700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1974
Cell Significance Index: 23.2800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1855
Cell Significance Index: 13.1200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1803
Cell Significance Index: 3.0900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1742
Cell Significance Index: 6.1200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1635
Cell Significance Index: 3.9200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1633
Cell Significance Index: 222.0000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1439
Cell Significance Index: 24.5800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1353
Cell Significance Index: 9.3600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0679
Cell Significance Index: 8.7100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0032
Cell Significance Index: 0.6100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0021
Cell Significance Index: -0.1400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0075
Cell Significance Index: -0.7400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0144
Cell Significance Index: -0.4100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0160
Cell Significance Index: -2.0700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0180
Cell Significance Index: -0.4900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0297
Cell Significance Index: -18.5600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0400
Cell Significance Index: -29.3600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0465
Cell Significance Index: -34.4800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0589
Cell Significance Index: -44.6000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0729
Cell Significance Index: -41.0900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.0863
Cell Significance Index: -0.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1695
Cell Significance Index: -17.3100 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.2152
Cell Significance Index: -1.3000 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.2418
Cell Significance Index: -5.9000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2555
Cell Significance Index: -53.8100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2650
Cell Significance Index: -76.2400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2753
Cell Significance Index: -40.0200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4211
Cell Significance Index: -26.5400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.4419
Cell Significance Index: -11.8400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.4562
Cell Significance Index: -7.6900 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.4719
Cell Significance Index: -5.8500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4865
Cell Significance Index: -55.7400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.5048
Cell Significance Index: -26.5100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5097
Cell Significance Index: -53.0700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5119
Cell Significance Index: -59.6600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.5657
Cell Significance Index: -64.5700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.6091
Cell Significance Index: -8.3100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6370
Cell Significance Index: -18.2600 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.6456
Cell Significance Index: -9.2900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.7493
Cell Significance Index: -18.7300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.7764
Cell Significance Index: -46.6100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.8127
Cell Significance Index: -28.2400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.8627
Cell Significance Index: -68.3300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.9197
Cell Significance Index: -27.0100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.9657
Cell Significance Index: -14.4700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.9710
Cell Significance Index: -14.3400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.0049
Cell Significance Index: -16.8200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.0604
Cell Significance Index: -23.2200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -1.1983
Cell Significance Index: -14.2900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.2236
Cell Significance Index: -39.1900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.2325
Cell Significance Index: -26.3500 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -1.2441
Cell Significance Index: -17.8700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.2590
Cell Significance Index: -77.1900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.4058
Cell Significance Index: -20.7500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3488550504
Symbol: UBE2K_HUMAN
Name: Ubiquitin-conjugating enzyme E2 K
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8702625
Title: Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme.
PubMed ID: 8702625
PubMed ID: 10634809
Title: Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis.
PubMed ID: 10634809
PubMed ID: 10675012
Title: Regulation of macrophage-specific gene expression by degenerated lipoproteins.
PubMed ID: 10675012
DOI: 10.1002/(sici)1522-2683(20000101)21:2<338::aid-elps338>3.0.co;2-9
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16714285
Title: NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).
PubMed ID: 16714285
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 16868077
Title: E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system.
PubMed ID: 16868077
PubMed ID: 17873885
Title: E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
PubMed ID: 17873885
DOI: 10.1038/nsmb1295
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20061386
Title: The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.
PubMed ID: 20061386
PubMed ID: 19906396
Title: Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis.
PubMed ID: 19906396
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21532592
Title: UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids.
PubMed ID: 21532592
DOI: 10.1038/nature09966
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 19407372
Title: Structure of full-length ubiquitin-conjugating enzyme E2-25K (Huntingtin-interacting protein 2).
PubMed ID: 19407372
Sequence Information:
- Length: 200
- Mass: 22407
- Checksum: E40668099ED25828
- Sequence:
MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA EPDDPQDAVV ANQYKQNPEM FKQTARLWAH VYAGAPVSSP EYTKKIENLC AMGFDRNAVI VALSSKSWDV ETATELLLSN
Genular Protein ID: 2535287320
Symbol: B3KSH4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 97
- Mass: 10667
- Checksum: C6B08374B5889D0C
- Sequence:
MTLRTVLLSL QALLAAAEPD DPQDAVVANQ YKQNPEMFKQ TARLWAHVYA GAPVSSPEYT KKIENLCAMG FDRNAVIVAL SSKSWDVETA TELLLSN
Genular Protein ID: 1974678236
Symbol: B4DIZ2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 139
- Mass: 15810
- Checksum: ECCD8F30C4222872
- Sequence:
MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI KIPETYPFNP PKYKQNPEMF KQTARLWAHV YAGAPVSSPE YTKKIENLCA MGFDRNAVIV ALSSKSWDVE TATELLLSN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.