Details for: HIVEP2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 357.8059
Cell Significance Index: -55.6600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 219.9151
Cell Significance Index: -55.7800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 119.3122
Cell Significance Index: -56.3300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 109.2412
Cell Significance Index: -44.3800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 46.4418
Cell Significance Index: -44.3400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 45.1557
Cell Significance Index: -55.6800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 20.2549
Cell Significance Index: -54.2600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 15.9175
Cell Significance Index: -48.8900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 15.0919
Cell Significance Index: -33.0300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.1597
Cell Significance Index: -55.8800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 3.3362
Cell Significance Index: 147.5700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 3.0694
Cell Significance Index: 116.2300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.7445
Cell Significance Index: 78.3200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.7037
Cell Significance Index: 969.7600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6319
Cell Significance Index: 527.9600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.2037
Cell Significance Index: 148.1800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.0463
Cell Significance Index: 58.6600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.8278
Cell Significance Index: 140.2600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.5329
Cell Significance Index: 1060.2000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.2031
Cell Significance Index: 228.9500 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.0915
Cell Significance Index: 21.3000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.0698
Cell Significance Index: 212.3100 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.9268
Cell Significance Index: 13.3300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.8864
Cell Significance Index: 15.1900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.8061
Cell Significance Index: 20.7200 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 0.6391
Cell Significance Index: 8.5300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6360
Cell Significance Index: 574.2300 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.6166
Cell Significance Index: 15.0500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5588
Cell Significance Index: 55.2800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.5481
Cell Significance Index: 348.0800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5458
Cell Significance Index: 15.7300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.4650
Cell Significance Index: 9.9400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.4435
Cell Significance Index: 54.5300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.4393
Cell Significance Index: 27.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3533
Cell Significance Index: 63.7000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.3330
Cell Significance Index: 151.1500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3041
Cell Significance Index: 15.8400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2706
Cell Significance Index: 44.0200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2443
Cell Significance Index: 12.6900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2440
Cell Significance Index: 6.1000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2366
Cell Significance Index: 445.4400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.2023
Cell Significance Index: 11.3500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1971
Cell Significance Index: 107.6300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1339
Cell Significance Index: 59.2200 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1076
Cell Significance Index: 0.6500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0866
Cell Significance Index: 2.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0742
Cell Significance Index: 100.9100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0715
Cell Significance Index: 7.7800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0667
Cell Significance Index: 102.6900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0596
Cell Significance Index: 2.7000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0358
Cell Significance Index: 66.0700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0284
Cell Significance Index: 0.6100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0250
Cell Significance Index: 0.6800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0194
Cell Significance Index: 0.6800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0139
Cell Significance Index: 1.9200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0205
Cell Significance Index: -2.9800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0276
Cell Significance Index: -17.2400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0307
Cell Significance Index: -22.7100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0334
Cell Significance Index: -5.7000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0380
Cell Significance Index: -21.4100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0546
Cell Significance Index: -1.3100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0575
Cell Significance Index: -42.1300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0753
Cell Significance Index: -56.9900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0861
Cell Significance Index: -9.8300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1083
Cell Significance Index: -5.0500 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.1303
Cell Significance Index: -1.6900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1329
Cell Significance Index: -17.1700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.1414
Cell Significance Index: -2.0300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1543
Cell Significance Index: -32.4900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1570
Cell Significance Index: -45.1800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1674
Cell Significance Index: -11.5800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1685
Cell Significance Index: -19.3100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1779
Cell Significance Index: -8.3600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2055
Cell Significance Index: -23.9500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2059
Cell Significance Index: -4.3700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2284
Cell Significance Index: -26.9400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.2407
Cell Significance Index: -14.4500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2485
Cell Significance Index: -16.0400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2682
Cell Significance Index: -34.3800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3232
Cell Significance Index: -8.6300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.3475
Cell Significance Index: -3.2000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3553
Cell Significance Index: -26.4800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3638
Cell Significance Index: -37.1600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3735
Cell Significance Index: -12.2300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.3745
Cell Significance Index: -5.1100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3775
Cell Significance Index: -39.3100 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.3938
Cell Significance Index: -4.8900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4619
Cell Significance Index: -14.7100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.4673
Cell Significance Index: -9.2400 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.4734
Cell Significance Index: -7.9700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.5728
Cell Significance Index: -40.5100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.6109
Cell Significance Index: -48.3800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.6124
Cell Significance Index: -8.7700 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.7008
Cell Significance Index: -14.0700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7583
Cell Significance Index: -46.4900 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.7688
Cell Significance Index: -8.4800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7874
Cell Significance Index: -41.3400 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.8182
Cell Significance Index: -12.0800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.8222
Cell Significance Index: -20.5100 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.8367
Cell Significance Index: -12.3500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3105867179
Symbol: ZEP2_HUMAN
Name: Transcription factor HIVEP2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2022670
Title: HIV-EP2, a new member of the gene family encoding the human immunodeficiency virus type 1 enhancer-binding protein. Comparison with HIV-EP1/PRDII-BF1/MBP-1.
PubMed ID: 2022670
PubMed ID: 1409593
Title: Structure and expression of MBP-2: a 275 kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class 1 genes.
PubMed ID: 1409593
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 2247438
Title: Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.
PubMed ID: 2247438
PubMed ID: 10207097
Title: Activation of somatostatin receptor II expression by transcription factors MIBP1 and SEF-2 in the murine brain.
PubMed ID: 10207097
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 23020937
Title: Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study.
PubMed ID: 23020937
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 26153216
Title: Loss-of-function variants in HIVEP2 are a cause of intellectual disability.
PubMed ID: 26153216
Sequence Information:
- Length: 2446
- Mass: 269053
- Checksum: 482E2C577EF9449A
- Sequence:
MDTGDTALGQ KATSRSGETD KASGRWRQEQ SAVIKMSTFG SHEGQRQPQI EPEQIGNTAS AQLFGSGKLA SPSEVVQQVA EKQYPPHRPS PYSCQHSLSF PQHSLPQGVM HSTKPHQSLE GPPWLFPGPL PSVASEDLFP FPIHGHSGGY PRKKISSLNP AYSQYSQKSI EQAEEAHKKE HKPKKPGKYI CPYCSRACAK PSVLKKHIRS HTGERPYPCI PCGFSFKTKS NLYKHRKSHA HAIKAGLVPF TESAVSKLDL EAGFIDVEAE IHSDGEQSTD TDEESSLFAE ASDKMSPGPP IPLDIASRGG YHGSLEESLG GPMKVPILII PKSGIPLPNE SSQYIGPDML PNPSLNTKAD DSHTVKQKLA LRLSEKKGQD SEPSLNLLSP HSKGSTDSGY FSRSESAEQQ ISPPNTNAKS YEEIIFGKYC RLSPRNALSV TTTSQERAAM GRKGIMEPLP HVNTRLDVKM FEDPVSQLIP SKGDVDPSQT SMLKSTKFNS ESRQPQIIPS SIRNEGKLYP ANFQGSNPVL LEAPVDSSPL IRSNSVPTSS ATNLTIPPSL RGSHSFDERM TGSDDVFYPG TVGIPPQRML RRQAAFELPS VQEGHVEVEH HGRMLKGISS SSLKEKKLSP GDRVGYDYDV CRKPYKKWED SETPKQNYRD ISCLSSLKHG GEYFMDPVVP LQGVPSMFGT TCENRKRRKE KSVGDEEDTP MICSSIVSTP VGIMASDYDP KLQMQEGVRS GFAMAGHENL SHGHTERFDP CRPQLQPGSP SLVSEESPSA IDSDKMSDLG GRKPPGNVIS VIQHTNSLSR PNSFERSESA ELVACTQDKA PSPSETCDSE ISEAPVSPEW APPGDGAESG GKPSPSQQVQ QQSYHTQPRL VRQHNIQVPE IRVTEEPDKP EKEKEAQSKE PEKPVEEFQW PQRSETLSQL PAEKLPPKKK RLRLADMEHS SGESSFESTG TGLSRSPSQE SNLSHSSSFS MSFEREETSK LSALPKQDEF GKHSEFLTVP AGSYSLSVPG HHHQKEMRRC SSEQMPCPHP AEVPEVRSKS FDYGNLSHAP VSGAAASTVS PSRERKKCFL VRQASFSGSP EISQGEVGMD QSVKQEQLEH LHAGLRSGWH HGPPAVLPPL QQEDPGKQVA GPCPPLSSGP LHLAQPQIMH MDSQESLRNP LIQPTSYMTS KHLPEQPHLF PHQETIPFSP IQNALFQFQY PTVCMVHLPA QQPPWWQAHF PHPFAQHPQK SYGKPSFQTE IHSSYPLEHV AEHTGKKPAE YAHTKEQTYP CYSGASGLHP KNLLPKFPSD QSSKSTETPS EQVLQEDFAS ANAGSLQSLP GTVVPVRIQT HVPSYGSVMY TSISQILGQN SPAIVICKVD ENMTQRTLVT NAAMQGIGFN IAQVLGQHAG LEKYPIWKAP QTLPLGLESS IPLCLPSTSD SVATLGGSKR MLSPASSLEL FMETKQQKRV KEEKMYGQIV EELSAVELTN SDIKKDLSRP QKPQLVRQGC ASEPKDGLQS GSSSFSSLSP SSSQDYPSVS PSSREPFLPS KEMLSGSRAP LPGQKSSGPS ESKESSDELD IDETASDMSM SPQSSSLPAG DGQLEEEGKG HKRPVGMLVR MASAPSGNVA DSTLLLTDMA DFQQILQFPS LRTTTTVSWC FLNYTKPNYV QQATFKSSVY ASWCISSCNP NPSGLNTKTT LALLRSKQKI TAEIYTLAAM HRPGTGKLTS SSAWKQFTQM KPDASFLFGS KLERKLVGNI LKERGKGDIH GDKDIGSKQT EPIRIKIFEG GYKSNEDYVY VRGRGRGKYI CEECGIRCKK PSMLKKHIRT HTDVRPYVCK LCNFAFKTKG NLTKHMKSKA HMKKCLELGV SMTSVDDTET EEAENLEDLH KAAEKHSMSS ISTDHQFSDA EESDGEDGDD NDDDDEDEDD FDDQGDLTPK TRSRSTSPQP PRFSSLPVNV GAVPHGVPSD SSLGHSSLIS YLVTLPSIRV TQLMTPSDSC EDTQMTEYQR LFQSKSTDSE PDKDRLDIPS CMDEECMLPS EPSSSPRDFS PSSHHSSPGY DSSPCRDNSP KRYLIPKGDL SPRRHLSPRR DLSPMRHLSP RKEAALRREM SQRDVSPRRH LSPRRPVSPG KDITARRDLS PRRERRYMTT IRAPSPRRAL YHNPPLSMGQ YLQAEPIVLG PPNLRRGLPQ VPYFSLYGDQ EGAYEHPGSS LFPEGPNDYV FSHLPLHSQQ QVRAPIPMVP VGGIQMVHSM PPALSSLHPS PTLPLPMEGF EEKKGASGES FSKDPYVLSK QHEKRGPHAL QSSGPPSTPS SPRLLMKQST SEDSLNATER EQEENIQTCT KAIASLRIAT EEAALLGPDQ PARVQEPHQN PLGSAHVSIR HFSRPEPGQP CTSATHPDLH DGEKDNFGTS QTPLAHSTFY SKSCVDDKQL DFHSSKELSS STEESKDPSS EKSQLH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.