Details for: NR4A1

Gene ID: 3164

Symbol: NR4A1

Ensembl ID: ENSG00000123358

Description: nuclear receptor subfamily 4 group A member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 393.9690
    Cell Significance Index: -61.2800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 226.6568
    Cell Significance Index: -57.4900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 144.6907
    Cell Significance Index: -59.6100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 128.7801
    Cell Significance Index: -60.8000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 126.4716
    Cell Significance Index: -51.3800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 116.5274
    Cell Significance Index: -59.9400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 90.1610
    Cell Significance Index: -60.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 55.8999
    Cell Significance Index: -53.3700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 49.8071
    Cell Significance Index: -61.4100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 21.1023
    Cell Significance Index: -56.5300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 15.6435
    Cell Significance Index: -61.7300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.4464
    Cell Significance Index: -41.3000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.5632
    Cell Significance Index: -20.9300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 4.7530
    Cell Significance Index: 109.8100
  • Cell Name: theca cell (CL0000503)
    Fold Change: 4.4476
    Cell Significance Index: 26.1300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 4.3495
    Cell Significance Index: 124.6800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 3.8918
    Cell Significance Index: 32.6900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 3.5904
    Cell Significance Index: 167.4000
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 2.9459
    Cell Significance Index: 11.2800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.5789
    Cell Significance Index: 330.6000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.2742
    Cell Significance Index: 103.0800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.2523
    Cell Significance Index: 60.3500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0731
    Cell Significance Index: 59.7300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.0511
    Cell Significance Index: 55.8300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.8717
    Cell Significance Index: 40.5500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.8092
    Cell Significance Index: 248.4600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.6780
    Cell Significance Index: 741.8900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.5858
    Cell Significance Index: 82.3800
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 1.5655
    Cell Significance Index: 32.6500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.4992
    Cell Significance Index: 106.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.4697
    Cell Significance Index: 112.7900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.4002
    Cell Significance Index: 20.9800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.2455
    Cell Significance Index: 17.4700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0981
    Cell Significance Index: 135.0300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0722
    Cell Significance Index: 968.1100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.8310
    Cell Significance Index: 14.6900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8226
    Cell Significance Index: 148.2900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8036
    Cell Significance Index: 79.4900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6702
    Cell Significance Index: 127.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.6640
    Cell Significance Index: 1250.2000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6357
    Cell Significance Index: 103.4000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.5857
    Cell Significance Index: 15.4000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5380
    Cell Significance Index: 293.8400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5326
    Cell Significance Index: 68.8100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4878
    Cell Significance Index: 25.4100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.4160
    Cell Significance Index: 188.8200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3480
    Cell Significance Index: 37.8500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.3346
    Cell Significance Index: 24.9400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2638
    Cell Significance Index: 9.2700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2475
    Cell Significance Index: 15.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2412
    Cell Significance Index: 48.3900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2174
    Cell Significance Index: 138.0700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1687
    Cell Significance Index: 7.9300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1436
    Cell Significance Index: 16.9300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1175
    Cell Significance Index: 2.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1167
    Cell Significance Index: 80.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1063
    Cell Significance Index: 163.7100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0456
    Cell Significance Index: 4.7500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0322
    Cell Significance Index: 23.6200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0104
    Cell Significance Index: 1.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0011
    Cell Significance Index: 0.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0041
    Cell Significance Index: -0.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0088
    Cell Significance Index: -1.5000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0107
    Cell Significance Index: -19.7600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0304
    Cell Significance Index: -22.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0325
    Cell Significance Index: -44.1300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0374
    Cell Significance Index: -23.3600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0627
    Cell Significance Index: -35.3500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0816
    Cell Significance Index: -29.2600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1016
    Cell Significance Index: -20.1600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1083
    Cell Significance Index: -22.8200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1511
    Cell Significance Index: -21.9600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1530
    Cell Significance Index: -17.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1817
    Cell Significance Index: -9.5400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1820
    Cell Significance Index: -52.3700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1950
    Cell Significance Index: -2.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2056
    Cell Significance Index: -5.4900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2118
    Cell Significance Index: -2.8900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2538
    Cell Significance Index: -3.6500
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: -0.3093
    Cell Significance Index: -0.9200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3368
    Cell Significance Index: -39.2500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3435
    Cell Significance Index: -14.0700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3655
    Cell Significance Index: -41.7200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3662
    Cell Significance Index: -5.6700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3852
    Cell Significance Index: -19.4700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.4931
    Cell Significance Index: -6.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5413
    Cell Significance Index: -13.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5483
    Cell Significance Index: -17.5600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.6807
    Cell Significance Index: -9.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6948
    Cell Significance Index: -55.0300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.6989
    Cell Significance Index: -13.6400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7410
    Cell Significance Index: -18.0800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7460
    Cell Significance Index: -50.1600
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.7596
    Cell Significance Index: -7.9300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.7665
    Cell Significance Index: -21.4200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.8128
    Cell Significance Index: -45.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.8404
    Cell Significance Index: -52.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8793
    Cell Significance Index: -53.9100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.9600
    Cell Significance Index: -8.8400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.9644
    Cell Significance Index: -16.1400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NR4A1 is a transcription factor that belongs to the nuclear receptor superfamily. It is activated by ligands such as CRH and FGF, which bind to specific DNA sequences, leading to the recruitment of co-activators and co-repressors. NR4A1 has a high degree of sequence homology with other nuclear receptors, including the NR1C2 and NR1I2 receptors. It is also highly expressed in specific cell types, including immune cells, fibroblasts, and smooth muscle cells. NR4A1 has a distinct pattern of expression, with high levels of expression in certain tissues, such as the mammary gland and the prostate. **Pathways and Functions** NR4A1 is involved in several signaling pathways, including: 1. **Apoptotic process**: NR4A1 regulates the expression of pro-apoptotic genes, such as BAX and PUMA, which are involved in the regulation of programmed cell death. 2. **Cell migration involved in sprouting angiogenesis**: NR4A1 regulates the expression of genes involved in cell migration and angiogenesis, such as VEGF and MMPs. 3. **Cellular response to corticotropin-releasing hormone stimulus**: NR4A1 is activated by CRH, which leads to the regulation of gene expression involved in stress response and inflammation. 4. **Cellular response to fibroblast growth factor stimulus**: NR4A1 regulates the expression of genes involved in cell growth and differentiation, such as FGF receptors and MAPK pathways. 5. **Chromatin remodeling**: NR4A1 regulates the expression of chromatin remodeling genes, such as HDACs and histone deacetylases. **Clinical Significance** NR4A1 has been implicated in several diseases, including: 1. **Cancer**: NR4A1 is overexpressed in several types of cancer, including breast, prostate, and lung cancer, and is associated with poor prognosis. 2. **Inflammatory disorders**: NR4A1 is involved in the regulation of inflammatory responses, and its dysregulation has been implicated in diseases such as arthritis and multiple sclerosis. 3. **Cardiovascular diseases**: NR4A1 regulates the expression of genes involved in cardiovascular disease, such as VEGF and MMPs. 4. **Neurological disorders**: NR4A1 is involved in the regulation of gene expression involved in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, NR4A1 is a transcription factor that plays a crucial role in regulating various cellular processes, including cell proliferation, differentiation, survival, and inflammation. Its dysregulation has been implicated in several diseases, including cancer, inflammatory disorders, and cardiovascular diseases. Further studies are needed to fully understand the mechanisms by which NR4A1 regulates gene expression and its role in disease pathogenesis.

Genular Protein ID: 3090185347

Symbol: NR4A1_HUMAN

Name: Nuclear receptor subfamily 4immunitygroup A member 1

UniProtKB Accession Codes:

P22736 B4DML7 Q15627 Q53Y00 Q6IBU8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EMBL 14 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 41 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 18 PDBsum 18 PIR 1 PRINTS 4 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 6 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2283997

Title: A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily.

PubMed ID: 2283997

DOI: 10.1210/mend-4-10-1438

PubMed ID: 2626032

Title: Isolation and characterization of human TR3 receptor: a member of steroid receptor superfamily.

PubMed ID: 2626032

DOI: 10.1016/0022-4731(89)90114-3

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1651101

Title: Phorbol ester, forskolin, and serum induction of a human colon nuclear hormone receptor gene related to the NUR 77/NGFI-B genes.

PubMed ID: 1651101

PubMed ID: 8121493

Title: Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas.

PubMed ID: 8121493

DOI: 10.1038/367277a0

PubMed ID: 9315652

Title: Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells.

PubMed ID: 9315652

DOI: 10.1128/mcb.17.10.5946

PubMed ID: 15509776

Title: Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting.

PubMed ID: 15509776

DOI: 10.1128/mcb.24.22.9705-9725.2004

PubMed ID: 15466594

Title: Negative cross-talk between the human orphan nuclear receptor Nur77/NAK-1/TR3 and nuclear factor-kappaB.

PubMed ID: 15466594

DOI: 10.1093/nar/gkh856

PubMed ID: 15459248

Title: CR6-interacting factor 1 interacts with orphan nuclear receptor Nur77 and inhibits its transactivation.

PubMed ID: 15459248

DOI: 10.1210/me.2004-0107

PubMed ID: 17360704

Title: RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

PubMed ID: 17360704

DOI: 10.1074/jbc.m700906200

PubMed ID: 17761950

Title: Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-alpha.

PubMed ID: 17761950

DOI: 10.1210/me.2007-0107

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18690216

Title: Cytosporone B is an agonist for nuclear orphan receptor Nur77.

PubMed ID: 18690216

DOI: 10.1038/nchembio.106

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20438716

Title: Regulation of Nur77 protein turnover through acetylation and deacetylation induced by p300 and HDAC1.

PubMed ID: 20438716

DOI: 10.1016/j.bcp.2010.04.026

PubMed ID: 22427340

Title: The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors.

PubMed ID: 22427340

DOI: 10.1161/circresaha.111.258814

PubMed ID: 37001519

Title: The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome.

PubMed ID: 37001519

DOI: 10.1016/j.immuni.2023.03.003

PubMed ID: 22983157

Title: The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK.

PubMed ID: 22983157

DOI: 10.1038/nchembio.1069

Sequence Information:

  • Length: 598
  • Mass: 64463
  • Checksum: 41DAAEA7C25FDA22
  • Sequence:
    • MPCIQAQYGT PAPSPGPRDH LASDPLTPEF IKPTMDLASP EAAPAAPTAL PSFSTFMDGY 
TGEFDTFLYQ LPGTVQPCSS ASSSASSTSS SSATSPASAS FKFEDFQVYG CYPGPLSGPV 
DEALSSSGSD YYGSPCSAPS PSTPSFQPPQ LSPWDGSFGH FSPSQTYEGL RAWTEQLPKA 
SGPPQPPAFF SFSPPTGPSP SLAQSPLKLF PSQATHQLGE GESYSMPTAF PGLAPTSPHL 
EGSGILDTPV TSTKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK 
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP SKPKQPPDAS 
PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPHFGKEDA GDVQQFYDLL SGSLEVIRKW 
AEKIPGFAEL SPADQDLLLE SAFLELFILR LAYRSKPGEG KLIFCSGLVL HRLQCARGFG 
DWIDSILAFS RSLHSLLVDV PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVA 
AVAGEPQPAS CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF

Genular Protein ID: 1707725433

Symbol: F5GXF0_HUMAN

Name: N/A

UniProtKB Accession Codes:

F5GXF0

Database IDs:

ARBA 14 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 2 GeneTree 1 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 4 PROSITE 5 PeptideAtlas 2 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

Sequence Information:

  • Length: 652
  • Mass: 70451
  • Checksum: FFA44C6BD5A9BC51
  • Sequence:
    • MTSAQYKIKI LIEGLHHGQR PGPAPPRQPG SFCWALKADG IMWLAKACWS IQSEMPCIQA 
QYGTPAPSPG PRDHLASDPL TPEFIKPTMD LASPEAAPAA PTALPSFSTF MDGYTGEFDT 
FLYQLPGTVQ PCSSASSSAS STSSSSATSP ASASFKFEDF QVYGCYPGPL SGPVDEALSS 
SGSDYYGSPC SAPSPSTPSF QPPQLSPWDG SFGHFSPSQT YEGLRAWTEQ LPKASGPPQP 
PAFFSFSPPT GPSPSLAQSP LKLFPSQATH QLGEGESYSM PTAFPGLAPT SPHLEGSGIL 
DTPVTSTKAR SGAPGGSEGR CAVCGDNASC QHYGVRTCEG CKGFFKRTVQ KNAKYICLAN 
KDCPVDKRRR NRCQFCRFQK CLAVGMVKEV VRTDSLKGRR GRLPSKPKQP PDASPANLLT 
SLVRAHLDSG PSTAKLDYSK FQELVLPHFG KEDAGDVQQF YDLLSGSLEV IRKWAEKIPG 
FAELSPADQD LLLESAFLEL FILRLAYRSK PGEGKLIFCS GLVLHRLQCA RGFGDWIDSI 
LAFSRSLHSL LVDVPAFACL SALVLITDRH GLQEPRRVEE LQNRIASCLK EHVAAVAGEP 
QPASCLSRLL GKLPELRTLC TQGLQRIFYL KLEDLVPPPP IIDKIFMDTL PF

Genular Protein ID: 499753470

Symbol: Q6ZMM6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ZMM6

Database IDs:

ARBA 14 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 4 PROSITE 5 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 652
  • Mass: 70421
  • Checksum: 0FA4496BD672D73C
  • Sequence:
    • MTSAQYKIKI LIEGLHHGQR PGPAPPRQPG SFCWALKADG IMWLAKACWS IQSEMPCIQA 
QYGTPAPSPG PRDHLASDPL TPEFIKPTMD LASPEAAPAA PTALPSFSTF MDGYTGEFDT 
FLYQLPGTVQ PCSSASSSAS STSSSSATSP ASASFKFEDF QVYGCYPGPL SGPVDEALSS 
SGSDYYGSPC SAPSPSTPSF QPPQLSPWDG SFGHFSPSQT YEGLRAWTEQ LPKASGPPQP 
PAFFSFSPPT GPSPSLAQSP LKLFPSQATH QLGEGESYSM PTAFPGLAPT SPHLEGSGIL 
DTPVTSTKAR SGAPGGSEGR CAVCGDNASC QHYGVRTCEG CKGFFKRTVQ KNAKYICLAN 
KDCPVDKRRR NRCQFCRFQK CLAVGMVKEV VRTDSLKGRR GRLPSKPKQP PDASPANLLT 
SLVRAHLDSG PSTAKLDYSK FQELVLPHFG KEDAGDVQQF YDLLSGSLEV IRKWAEKIPG 
FAELSPADQD LLLESAFLEL FILRLAYRSK PGEGKLIFCS GLVLHRLQCA RGFGDRIDSI 
LAFSRSLHSL LVDVPAFACL SALVLITDRH GLQEPRRVEE LQNRIASCLK EHVAAVAGEP 
QPASCLSRLL GKLPELRTLC TQGLQRIFYL KLEDLVPPPP IIDKIFMDTL PF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.