Details for: NR4A1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.78
Marker Score: 94470.5 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.78
Marker Score: 2965 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 2.65
Marker Score: 2256 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 2.61
Marker Score: 1064 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.53
Marker Score: 5758.5 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.49
Marker Score: 943 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 2.43
Marker Score: 3160 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 2.41
Marker Score: 4206 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.2
Marker Score: 3234 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 2.18
Marker Score: 1872 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.08
Marker Score: 656 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 2.07
Marker Score: 966 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.07
Marker Score: 2366 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 2.02
Marker Score: 4585.5 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 2.02
Marker Score: 1932 - Cell Name: theca cell (CL0000503)
Fold Change: 2.01
Marker Score: 1438 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 1.99
Marker Score: 675 - Cell Name: IgA plasma cell (CL0000987)
Fold Change: 1.97
Marker Score: 1677 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.96
Marker Score: 7255 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.96
Marker Score: 486 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.95
Marker Score: 611 - Cell Name: inflammatory cell (CL0009002)
Fold Change: 1.94
Marker Score: 835 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.94
Marker Score: 8367 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 1.93
Marker Score: 558 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.92
Marker Score: 1915 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.91
Marker Score: 5289 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.9
Marker Score: 7931.5 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.89
Marker Score: 788.5 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.88
Marker Score: 1471.5 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.88
Marker Score: 4117.5 - Cell Name: epithelial cell (CL0000066)
Fold Change: 1.86
Marker Score: 2954 - Cell Name: fibroblast (CL0000057)
Fold Change: 1.83
Marker Score: 1770 - Cell Name: B-1b B cell (CL0000821)
Fold Change: 1.83
Marker Score: 420.5 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.82
Marker Score: 2989.5 - Cell Name: reticular cell (CL0000432)
Fold Change: 1.81
Marker Score: 661 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 1.77
Marker Score: 1162 - Cell Name: stromal cell (CL0000499)
Fold Change: 1.75
Marker Score: 2050 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 1.75
Marker Score: 4222 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 1.75
Marker Score: 10365 - Cell Name: chondrocyte (CL0000138)
Fold Change: 1.71
Marker Score: 771 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.67
Marker Score: 3144 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 1.67
Marker Score: 4367 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 1.66
Marker Score: 10806 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 1.64
Marker Score: 1642 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.64
Marker Score: 470 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.61
Marker Score: 1696 - Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
Fold Change: 1.6
Marker Score: 4151 - Cell Name: muscle cell (CL0000187)
Fold Change: 1.6
Marker Score: 453 - Cell Name: club cell (CL0000158)
Fold Change: 1.59
Marker Score: 1861 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 1.59
Marker Score: 8377 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 1.56
Marker Score: 646 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 1.56
Marker Score: 537 - Cell Name: renal principal cell (CL0005009)
Fold Change: 1.54
Marker Score: 1188 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 1.53
Marker Score: 3884 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 1.52
Marker Score: 752 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.51
Marker Score: 486 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.5
Marker Score: 381.5 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.48
Marker Score: 4027 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 1.47
Marker Score: 342 - Cell Name: paneth cell (CL0000510)
Fold Change: 1.47
Marker Score: 1023 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.46
Marker Score: 588 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 1.45
Marker Score: 753 - Cell Name: mural cell (CL0008034)
Fold Change: 1.45
Marker Score: 166160 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.44
Marker Score: 332 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 1.44
Marker Score: 2086 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.43
Marker Score: 2849 - Cell Name: pericyte (CL0000669)
Fold Change: 1.42
Marker Score: 827 - Cell Name: adventitial cell (CL0002503)
Fold Change: 1.42
Marker Score: 349.5 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.41
Marker Score: 525 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.4
Marker Score: 15734 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.39
Marker Score: 24741 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.39
Marker Score: 13941 - Cell Name: secretory cell (CL0000151)
Fold Change: 1.38
Marker Score: 2527 - Cell Name: kidney loop of Henle epithelial cell (CL1000909)
Fold Change: 1.38
Marker Score: 864 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 1.38
Marker Score: 709 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 1.37
Marker Score: 1226 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.37
Marker Score: 1230 - Cell Name: group 3 innate lymphoid cell (CL0001071)
Fold Change: 1.35
Marker Score: 569 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.35
Marker Score: 2079 - Cell Name: Mueller cell (CL0000636)
Fold Change: 1.35
Marker Score: 1871.5 - Cell Name: fibroblast of connective tissue of prostate (CL1000299)
Fold Change: 1.34
Marker Score: 333 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.34
Marker Score: 943 - Cell Name: vascular associated smooth muscle cell (CL0000359)
Fold Change: 1.34
Marker Score: 613 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 1.33
Marker Score: 1011 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 1.33
Marker Score: 333 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 1.32
Marker Score: 1635.5 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 1.31
Marker Score: 334 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.31
Marker Score: 760 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.3
Marker Score: 1243 - Cell Name: dendritic cell (CL0000451)
Fold Change: 1.3
Marker Score: 891 - Cell Name: leukocyte (CL0000738)
Fold Change: 1.3
Marker Score: 745 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.3
Marker Score: 20280 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.28
Marker Score: 1411 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.27
Marker Score: 724 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.27
Marker Score: 1795 - Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
Fold Change: 1.26
Marker Score: 287 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 1.26
Marker Score: 7684 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.26
Marker Score: 8206 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 1.26
Marker Score: 273 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.25
Marker Score: 2939
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Other Information
Genular Protein ID: 3090185347
Symbol: NR4A1_HUMAN
Name: Nuclear receptor subfamily 4immunitygroup A member 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2283997
Title: A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily.
PubMed ID: 2283997
PubMed ID: 2626032
Title: Isolation and characterization of human TR3 receptor: a member of steroid receptor superfamily.
PubMed ID: 2626032
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1651101
Title: Phorbol ester, forskolin, and serum induction of a human colon nuclear hormone receptor gene related to the NUR 77/NGFI-B genes.
PubMed ID: 1651101
PubMed ID: 8121493
Title: Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas.
PubMed ID: 8121493
DOI: 10.1038/367277a0
PubMed ID: 9315652
Title: Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells.
PubMed ID: 9315652
PubMed ID: 15509776
Title: Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting.
PubMed ID: 15509776
PubMed ID: 15466594
Title: Negative cross-talk between the human orphan nuclear receptor Nur77/NAK-1/TR3 and nuclear factor-kappaB.
PubMed ID: 15466594
DOI: 10.1093/nar/gkh856
PubMed ID: 15459248
Title: CR6-interacting factor 1 interacts with orphan nuclear receptor Nur77 and inhibits its transactivation.
PubMed ID: 15459248
DOI: 10.1210/me.2004-0107
PubMed ID: 17360704
Title: RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.
PubMed ID: 17360704
PubMed ID: 17761950
Title: Orphan receptor TR3 attenuates the p300-induced acetylation of retinoid X receptor-alpha.
PubMed ID: 17761950
DOI: 10.1210/me.2007-0107
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18690216
Title: Cytosporone B is an agonist for nuclear orphan receptor Nur77.
PubMed ID: 18690216
DOI: 10.1038/nchembio.106
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20438716
Title: Regulation of Nur77 protein turnover through acetylation and deacetylation induced by p300 and HDAC1.
PubMed ID: 20438716
PubMed ID: 22427340
Title: The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors.
PubMed ID: 22427340
PubMed ID: 37001519
Title: The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome.
PubMed ID: 37001519
PubMed ID: 22983157
Title: The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK.
PubMed ID: 22983157
Sequence Information:
- Length: 598
- Mass: 64463
- Checksum: 41DAAEA7C25FDA22
- Sequence:
MPCIQAQYGT PAPSPGPRDH LASDPLTPEF IKPTMDLASP EAAPAAPTAL PSFSTFMDGY TGEFDTFLYQ LPGTVQPCSS ASSSASSTSS SSATSPASAS FKFEDFQVYG CYPGPLSGPV DEALSSSGSD YYGSPCSAPS PSTPSFQPPQ LSPWDGSFGH FSPSQTYEGL RAWTEQLPKA SGPPQPPAFF SFSPPTGPSP SLAQSPLKLF PSQATHQLGE GESYSMPTAF PGLAPTSPHL EGSGILDTPV TSTKARSGAP GGSEGRCAVC GDNASCQHYG VRTCEGCKGF FKRTVQKNAK YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP SKPKQPPDAS PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPHFGKEDA GDVQQFYDLL SGSLEVIRKW AEKIPGFAEL SPADQDLLLE SAFLELFILR LAYRSKPGEG KLIFCSGLVL HRLQCARGFG DWIDSILAFS RSLHSLLVDV PAFACLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVA AVAGEPQPAS CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF
Genular Protein ID: 499753470
Symbol: Q6ZMM6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 652
- Mass: 70421
- Checksum: 0FA4496BD672D73C
- Sequence:
MTSAQYKIKI LIEGLHHGQR PGPAPPRQPG SFCWALKADG IMWLAKACWS IQSEMPCIQA QYGTPAPSPG PRDHLASDPL TPEFIKPTMD LASPEAAPAA PTALPSFSTF MDGYTGEFDT FLYQLPGTVQ PCSSASSSAS STSSSSATSP ASASFKFEDF QVYGCYPGPL SGPVDEALSS SGSDYYGSPC SAPSPSTPSF QPPQLSPWDG SFGHFSPSQT YEGLRAWTEQ LPKASGPPQP PAFFSFSPPT GPSPSLAQSP LKLFPSQATH QLGEGESYSM PTAFPGLAPT SPHLEGSGIL DTPVTSTKAR SGAPGGSEGR CAVCGDNASC QHYGVRTCEG CKGFFKRTVQ KNAKYICLAN KDCPVDKRRR NRCQFCRFQK CLAVGMVKEV VRTDSLKGRR GRLPSKPKQP PDASPANLLT SLVRAHLDSG PSTAKLDYSK FQELVLPHFG KEDAGDVQQF YDLLSGSLEV IRKWAEKIPG FAELSPADQD LLLESAFLEL FILRLAYRSK PGEGKLIFCS GLVLHRLQCA RGFGDRIDSI LAFSRSLHSL LVDVPAFACL SALVLITDRH GLQEPRRVEE LQNRIASCLK EHVAAVAGEP QPASCLSRLL GKLPELRTLC TQGLQRIFYL KLEDLVPPPP IIDKIFMDTL PF
Genular Protein ID: 1707725433
Symbol: F5GXF0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
Sequence Information:
- Length: 652
- Mass: 70451
- Checksum: FFA44C6BD5A9BC51
- Sequence:
MTSAQYKIKI LIEGLHHGQR PGPAPPRQPG SFCWALKADG IMWLAKACWS IQSEMPCIQA QYGTPAPSPG PRDHLASDPL TPEFIKPTMD LASPEAAPAA PTALPSFSTF MDGYTGEFDT FLYQLPGTVQ PCSSASSSAS STSSSSATSP ASASFKFEDF QVYGCYPGPL SGPVDEALSS SGSDYYGSPC SAPSPSTPSF QPPQLSPWDG SFGHFSPSQT YEGLRAWTEQ LPKASGPPQP PAFFSFSPPT GPSPSLAQSP LKLFPSQATH QLGEGESYSM PTAFPGLAPT SPHLEGSGIL DTPVTSTKAR SGAPGGSEGR CAVCGDNASC QHYGVRTCEG CKGFFKRTVQ KNAKYICLAN KDCPVDKRRR NRCQFCRFQK CLAVGMVKEV VRTDSLKGRR GRLPSKPKQP PDASPANLLT SLVRAHLDSG PSTAKLDYSK FQELVLPHFG KEDAGDVQQF YDLLSGSLEV IRKWAEKIPG FAELSPADQD LLLESAFLEL FILRLAYRSK PGEGKLIFCS GLVLHRLQCA RGFGDWIDSI LAFSRSLHSL LVDVPAFACL SALVLITDRH GLQEPRRVEE LQNRIASCLK EHVAAVAGEP QPASCLSRLL GKLPELRTLC TQGLQRIFYL KLEDLVPPPP IIDKIFMDTL PF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.