Details for: IGFBP2

Gene ID: 3485

Symbol: IGFBP2

Ensembl ID: ENSG00000115457

Description: insulin like growth factor binding protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 425.1497
    Cell Significance Index: -66.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 262.1003
    Cell Significance Index: -66.4800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 97.5825
    Cell Significance Index: -65.4800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 53.6516
    Cell Significance Index: -66.1500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 24.2342
    Cell Significance Index: -64.9200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.5533
    Cell Significance Index: -65.3200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 7.6815
    Cell Significance Index: 98.3800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 7.3956
    Cell Significance Index: 80.4000
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 5.9653
    Cell Significance Index: 29.7600
  • Cell Name: peg cell (CL4033014)
    Fold Change: 4.7339
    Cell Significance Index: 109.3700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 4.7040
    Cell Significance Index: 123.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.6611
    Cell Significance Index: 2545.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 4.6420
    Cell Significance Index: 241.1400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 4.2206
    Cell Significance Index: 518.9600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 3.9083
    Cell Significance Index: 65.8400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.8521
    Cell Significance Index: 104.8500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.7059
    Cell Significance Index: 508.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 2.5960
    Cell Significance Index: 443.2900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.4473
    Cell Significance Index: 441.1800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 2.1258
    Cell Significance Index: 24.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.0543
    Cell Significance Index: 263.3500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.7505
    Cell Significance Index: 36.6400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.4048
    Cell Significance Index: 24.8300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2780
    Cell Significance Index: 253.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.9230
    Cell Significance Index: 68.7900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.8086
    Cell Significance Index: 28.1000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5934
    Cell Significance Index: 41.0400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5445
    Cell Significance Index: 491.6600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5445
    Cell Significance Index: 24.6800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5430
    Cell Significance Index: 88.3100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4608
    Cell Significance Index: 87.7000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3368
    Cell Significance Index: 18.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3317
    Cell Significance Index: 32.8100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.1992
    Cell Significance Index: 2.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1944
    Cell Significance Index: 85.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1334
    Cell Significance Index: 97.8300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1170
    Cell Significance Index: 3.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0655
    Cell Significance Index: 2.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0209
    Cell Significance Index: -15.4800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0296
    Cell Significance Index: -5.9500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0307
    Cell Significance Index: -0.8900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0334
    Cell Significance Index: -62.9600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0394
    Cell Significance Index: -0.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0530
    Cell Significance Index: -97.7000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0634
    Cell Significance Index: -48.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0636
    Cell Significance Index: -97.9200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0639
    Cell Significance Index: -44.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0686
    Cell Significance Index: -42.8200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0717
    Cell Significance Index: -97.4800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0774
    Cell Significance Index: -5.4800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0784
    Cell Significance Index: -49.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1064
    Cell Significance Index: -60.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1083
    Cell Significance Index: -49.1600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.1473
    Cell Significance Index: -52.8500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1890
    Cell Significance Index: -54.3800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.2045
    Cell Significance Index: -2.8700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2160
    Cell Significance Index: -25.1700
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.2265
    Cell Significance Index: -1.7100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2287
    Cell Significance Index: -3.1200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2998
    Cell Significance Index: -18.4300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3043
    Cell Significance Index: -9.7500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3086
    Cell Significance Index: -3.2000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3305
    Cell Significance Index: -69.6100
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3372
    Cell Significance Index: -3.1100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3803
    Cell Significance Index: -49.1300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4338
    Cell Significance Index: -44.3100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4381
    Cell Significance Index: -63.6900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5015
    Cell Significance Index: -12.8900
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: -0.5084
    Cell Significance Index: -2.8900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5325
    Cell Significance Index: -62.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5387
    Cell Significance Index: -61.7200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5607
    Cell Significance Index: -64.0000
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: -0.5974
    Cell Significance Index: -3.5800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6085
    Cell Significance Index: -63.3600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6361
    Cell Significance Index: -50.3800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6405
    Cell Significance Index: -13.6400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6748
    Cell Significance Index: -18.0500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6934
    Cell Significance Index: -10.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7202
    Cell Significance Index: -46.4700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.7381
    Cell Significance Index: -56.6400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.7706
    Cell Significance Index: -46.2700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.7940
    Cell Significance Index: -22.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.8504
    Cell Significance Index: -39.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9155
    Cell Significance Index: -56.1300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.0143
    Cell Significance Index: -68.2000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.0205
    Cell Significance Index: -25.5100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.0678
    Cell Significance Index: -67.3000
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -1.1559
    Cell Significance Index: -9.5600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.1953
    Cell Significance Index: -24.8000
  • Cell Name: glioblast (CL0000030)
    Fold Change: -1.3791
    Cell Significance Index: -8.6600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.4752
    Cell Significance Index: -65.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.5338
    Cell Significance Index: -80.5300
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -1.6740
    Cell Significance Index: -14.4800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.6789
    Cell Significance Index: -58.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.6941
    Cell Significance Index: -45.4000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.7089
    Cell Significance Index: -64.7100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.7099
    Cell Significance Index: -62.7700
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -1.7719
    Cell Significance Index: -10.5200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -1.8143
    Cell Significance Index: -15.2400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.8892
    Cell Significance Index: -95.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IGFBP2 shares structural homology with other IGFBPs, but exhibits distinct differences in its expression pattern and function. It is a secreted protein that is produced in high quantities in the ovary and prostate, suggesting its involvement in reproductive and glandular functions. IGFBP2 is also expressed in thymocytes, where it may play a role in regulating T-cell development and function. **Pathways and Functions** IGFBP2 is involved in multiple signaling pathways, including: 1. **Regulation of IGF transport and uptake**: IGFBP2 binds to IGFs, modulating their activity and facilitating their transport and uptake by cells. 2. **Negative regulation of canonical Wnt signaling pathway**: IGFBP2 inhibits the Wnt/β-catenin signaling pathway, which is involved in cell proliferation, differentiation, and survival. 3. **Positive regulation of activated T-cell proliferation**: IGFBP2 promotes the proliferation of activated T cells, suggesting its involvement in immune responses. 4. **Regulation of insulin-like growth factor receptor signaling pathway**: IGFBP2 modulates the activity of the IGF receptor, influencing cell growth and differentiation. **Clinical Significance** IGFBP2 has been implicated in various diseases and conditions, including: 1. **Cancer**: IGFBP2 is overexpressed in several types of cancer, including prostate cancer, breast cancer, and colon cancer, suggesting its potential role as a tumor suppressor. 2. **Autoimmune diseases**: IGFBP2 has been linked to autoimmune diseases, such as rheumatoid arthritis and lupus, where it may play a role in regulating immune responses. 3. **Reproductive disorders**: IGFBP2 is involved in reproductive functions, including ovulation and fetal development, suggesting its potential role in infertility and pregnancy complications. 4. **Neurological disorders**: IGFBP2 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may play a role in modulating neuroinflammation and neuronal survival. In conclusion, IGFBP2 is a multifaceted gene that plays a crucial role in regulating IGF signaling pathways and beyond. Its involvement in various physiological and pathological processes makes it an attractive target for therapeutic interventions. Further research is needed to fully elucidate the functions of IGFBP2 and its potential applications in human disease.

Genular Protein ID: 4155540003

Symbol: IBP2_HUMAN

Name: Insulin-like growth factor-binding protein 2

UniProtKB Accession Codes:

P18065 Q14619 Q9UCL3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 18 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2479552

Title: Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2).

PubMed ID: 2479552

DOI: 10.1002/j.1460-2075.1989.tb08386.x

PubMed ID: 1697583

Title: Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.

PubMed ID: 1697583

DOI: 10.1016/s0021-9258(18)77200-1

PubMed ID: 1710112

Title: Structure and localization of the human insulin-like growth factor-binding protein 2 gene.

PubMed ID: 1710112

DOI: 10.1016/0006-291x(91)90420-c

PubMed ID: 1712312

Title: Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2).

PubMed ID: 1712312

DOI: 10.1016/0014-4835(91)90056-k

PubMed ID: 1376411

Title: Structure of the human insulin-like growth factor binding protein-2 gene.

PubMed ID: 1376411

DOI: 10.1210/mend.6.5.1376411

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1726837

Title: Purification from human cerebrospinal fluid of insulin-like growth factor binding proteins (IGFBPs). Isolation of IGFBP-2, an altered form of IGFBP-3 and a new IGFBP species.

PubMed ID: 1726837

PubMed ID: 19081843

Title: Duplication of the IGFBP-2 gene in teleost fish: protein structure and functionality conservation and gene expression divergence.

PubMed ID: 19081843

DOI: 10.1371/journal.pone.0003926

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17020769

Title: Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2).

PubMed ID: 17020769

DOI: 10.1016/j.jmb.2006.09.006

Sequence Information:

  • Length: 325
  • Mass: 34814
  • Checksum: 9E1436DBCCC6EA2A
  • Sequence:
    • MLPRVGCPAL PLPPPPLLPL LLLLLGASGG GGGARAEVLF RCPPCTPERL AACGPPPVAP 
PAAVAAVAGG ARMPCAELVR EPGCGCCSVC ARLEGEACGV YTPRCGQGLR CYPHPGSELP 
LQALVMGEGT CEKRRDAEYG ASPEQVADNG DDHSEGGLVE NHVDSTMNML GGGGSAGRKP 
LKSGMKELAV FREKVTEQHR QMGKGGKHHL GLEEPKKLRP PPARTPCQQE LDQVLERIST 
MRLPDERGPL EHLYSLHIPN CDKHGLYNLK QCKMSLNGQR GECWCVNPNT GKLIQGAPTI 
RGDPECHLFY NEQQEARGVH TQRMQ

Genular Protein ID: 3348336959

Symbol: C9JMY1_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9JMY1

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 181
  • Mass: 20281
  • Checksum: 7978686EE4472E92
  • Sequence:
    • MPCNNGDDHS EGGLVENHVD STMNMLGGGG SAGRKPLKSG MKELAVFREK VTEQHRQMGK 
GGKHHLGLEE PKKLRPPPAR TPCQQELDQV LERISTMRLP DERGPLEHLY SLHIPNCDKH 
GLYNLKQCKM SLNGQRGECW CVNPNTGKLI QGAPTIRGDP ECHLFYNEQQ EARGVHTQRM 
Q

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.