Details for: IL16
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: retina horizontal cell (CL0000745)
Fold Change: 4.71
Marker Score: 4517 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 4.56
Marker Score: 13522 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 3.27
Marker Score: 27653.5 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.06
Marker Score: 1143 - Cell Name: double negative T regulatory cell (CL0011024)
Fold Change: 1.93
Marker Score: 1866 - Cell Name: mature T cell (CL0002419)
Fold Change: 1.81
Marker Score: 17914 - Cell Name: naive B cell (CL0000788)
Fold Change: 1.8
Marker Score: 1611 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 1.75
Marker Score: 3059 - Cell Name: memory B cell (CL0000787)
Fold Change: 1.75
Marker Score: 1321 - Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 1.74
Marker Score: 2985.5 - Cell Name: class switched memory B cell (CL0000972)
Fold Change: 1.74
Marker Score: 1632 - Cell Name: centroblast (CL0009112)
Fold Change: 1.7
Marker Score: 840 - Cell Name: blood cell (CL0000081)
Fold Change: 1.69
Marker Score: 19646.5 - Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 1.68
Marker Score: 3288 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 1.66
Marker Score: 87734 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 1.62
Marker Score: 2897 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 1.61
Marker Score: 4525 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.61
Marker Score: 2277 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.56
Marker Score: 1132 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.55
Marker Score: 4603 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 1.54
Marker Score: 3766 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 1.52
Marker Score: 916 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.51
Marker Score: 1489 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 1.5
Marker Score: 6444 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 1.48
Marker Score: 4680 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 1.48
Marker Score: 3096.5 - Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
Fold Change: 1.43
Marker Score: 4176.5 - Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 1.4
Marker Score: 1556 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.39
Marker Score: 449 - Cell Name: B-1b B cell (CL0000821)
Fold Change: 1.39
Marker Score: 320 - Cell Name: germinal center B cell (CL0000844)
Fold Change: 1.38
Marker Score: 841 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: 1.37
Marker Score: 486.5 - Cell Name: mucosal invariant T cell (CL0000940)
Fold Change: 1.36
Marker Score: 1207 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.35
Marker Score: 603.5 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 1.29
Marker Score: 1547.5 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 1.28
Marker Score: 752 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.28
Marker Score: 332 - Cell Name: T follicular helper cell (CL0002038)
Fold Change: 1.26
Marker Score: 1048 - Cell Name: naive T cell (CL0000898)
Fold Change: 1.25
Marker Score: 803 - Cell Name: fat cell (CL0000136)
Fold Change: 1.24
Marker Score: 694 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 1.24
Marker Score: 1156 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.23
Marker Score: 812 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.22
Marker Score: 827 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 1.22
Marker Score: 7803.5 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 1.22
Marker Score: 370 - Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.21
Marker Score: 522 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 1.18
Marker Score: 588 - Cell Name: dendritic cell, human (CL0001056)
Fold Change: 1.17
Marker Score: 1193 - Cell Name: regulatory T cell (CL0000815)
Fold Change: 1.16
Marker Score: 1279 - Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
Fold Change: 1.15
Marker Score: 1700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.13
Marker Score: 4742 - Cell Name: centrocyte (CL0009111)
Fold Change: 1.13
Marker Score: 268 - Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
Fold Change: 1.1
Marker Score: 358 - Cell Name: follicular B cell (CL0000843)
Fold Change: 1.1
Marker Score: 1190 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 1.09
Marker Score: 801 - Cell Name: ILC1, human (CL0001077)
Fold Change: 1.08
Marker Score: 275 - Cell Name: Unknown (CL0000548)
Fold Change: 1.08
Marker Score: 787.5 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 1.08
Marker Score: 908 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.08
Marker Score: 2980 - Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
Fold Change: 1.06
Marker Score: 234 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.04
Marker Score: 2591.5 - Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
Fold Change: 1.02
Marker Score: 900 - Cell Name: memory regulatory T cell (CL0002678)
Fold Change: 1.02
Marker Score: 357 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.02
Marker Score: 422 - Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.02
Marker Score: 2762.5 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.02
Marker Score: 610 - Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
Fold Change: 1.01
Marker Score: 824 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 1.01
Marker Score: 6044 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71718 - Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
Fold Change: 1
Marker Score: 846 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47943 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 0.98
Marker Score: 1061 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30395 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.95
Marker Score: 492 - Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
Fold Change: 0.95
Marker Score: 587 - Cell Name: CD4-positive, CD25-positive, alpha-beta regulatory T cell (CL0000792)
Fold Change: 0.95
Marker Score: 253 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 0.95
Marker Score: 688 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.95
Marker Score: 447 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2403 - Cell Name: unswitched memory B cell (CL0000970)
Fold Change: 0.94
Marker Score: 553 - Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
Fold Change: 0.94
Marker Score: 309 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.94
Marker Score: 431 - Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: 0.93
Marker Score: 515 - Cell Name: B-1a B cell (CL0000820)
Fold Change: 0.92
Marker Score: 220 - Cell Name: conventional dendritic cell (CL0000990)
Fold Change: 0.91
Marker Score: 630 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2715 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.9
Marker Score: 362 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.89
Marker Score: 1736 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.88
Marker Score: 274 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.88
Marker Score: 316 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 0.88
Marker Score: 1034 - Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
Fold Change: 0.88
Marker Score: 198 - Cell Name: gamma-delta T cell (CL0000798)
Fold Change: 0.87
Marker Score: 588 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5252 - Cell Name: double negative thymocyte (CL0002489)
Fold Change: 0.86
Marker Score: 1192 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.85
Marker Score: 4843 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.84
Marker Score: 3454 - Cell Name: alpha-beta T cell (CL0000789)
Fold Change: 0.84
Marker Score: 635 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.84
Marker Score: 843 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 0.84
Marker Score: 607
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Other Information
Genular Protein ID: 1360267611
Symbol: IL16_HUMAN
Name: Pro-interleukin-16
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12923170
Title: PDZ domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits.
PubMed ID: 12923170
PubMed ID: 19906316
Title: Discovery of novel human transcript variants by analysis of intronic single-block EST with polyadenylation site.
PubMed ID: 19906316
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9990060
Title: GA-binding protein factors, in concert with the coactivator CREB binding protein/p300, control the induction of the interleukin 16 promoter in T lymphocytes.
PubMed ID: 9990060
PubMed ID: 8609984
PubMed ID: 7910967
Title: Molecular and functional analysis of a lymphocyte chemoattractant factor: association of biologic function with CD4 expression.
PubMed ID: 7910967
PubMed ID: 9422780
Title: Processing and activation of pro-interleukin-16 by caspase-3.
PubMed ID: 9422780
PubMed ID: 11032842
Title: Nuclear translocation of the N-terminal prodomain of interleukin-16.
PubMed ID: 11032842
PubMed ID: 11276202
Title: Gene regulation mediated by calcium signals in T lymphocytes.
PubMed ID: 11276202
DOI: 10.1038/86318
PubMed ID: 12450396
Title: Prointerleukin-16 contains a functional CcN motif that regulates nuclear localization.
PubMed ID: 12450396
DOI: 10.1021/bi020163v
PubMed ID: 12620798
Title: Binding of HTLV-1 tax oncoprotein to the precursor of interleukin-16, a T cell PDZ domain-containing protein.
PubMed ID: 12620798
PubMed ID: 14734747
Title: Nuclear pro-IL-16 regulation of T cell proliferation: p27(KIP1)-dependent G0/G1 arrest mediated by inhibition of Skp2 transcription.
PubMed ID: 14734747
PubMed ID: 18097041
Title: Pro-IL-16 recruits histone deacetylase 3 to the Skp2 core promoter through interaction with transcription factor GABP.
PubMed ID: 18097041
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 9699630
Title: Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site.
PubMed ID: 9699630
DOI: 10.1038/1376
Sequence Information:
- Length: 1332
- Mass: 141752
- Checksum: EDF68567B2AF120C
- Sequence:
MESHSRAGKS RKSAKFRSIS RSLMLCNAKT SDDGSSPDEK YPDPFEISLA QGKEGIFHSS VQLADTSEAG PSSVPDLALA SEAAQLQAAG NDRGKTCRRI FFMKESSTAS SREKPGKLEA QSSNFLFPKA CHQRARSNST SVNPYCTREI DFPMTKKSAA PTDRQPYSLC SNRKSLSQQL DCPAGKAAGT SRPTRSLSTA QLVQPSGGLQ ASVISNIVLM KGQAKGLGFS IVGGKDSIYG PIGIYVKTIF AGGAAAADGR LQEGDEILEL NGESMAGLTH QDALQKFKQA KKGLLTLTVR TRLTAPPSLC SHLSPPLCRS LSSSTCITKD SSSFALESPS APISTAKPNY RIMVEVSLQK EAGVGLGIGL CSVPYFQCIS GIFVHTLSPG SVAHLDGRLR CGDEIVEISD SPVHCLTLNE VYTILSHCDP GPVPIIVSRH PDPQVSEQQL KEAVAQAVEN TKFGKERHQW SLEGVKRLES SWHGRPTLEK EREKNSAPPH RRAQKVMIRS SSDSSYMSGS PGGSPGSGSA EKPSSDVDIS THSPSLPLAR EPVVLSIASS RLPQESPPLP ESRDSHPPLR LKKSFEILVR KPMSSKPKPP PRKYFKSDSD PQKSLEEREN SSCSSGHTPP TCGQEARELL PLLLPQEDTA GRSPSASAGC PGPGIGPQTK SSTEGEPGWR RASPVTQTSP IKHPLLKRQA RMDYSFDTTA EDPWVRISDC IKNLFSPIMS ENHGHMPLQP NASLNEEEGT QGHPDGTPPK LDTANGTPKV YKSADSSTVK KGPPVAPKPA WFRQSLKGLR NRASDPRGLP DPALSTQPAP ASREHLGSHI RASSSSSSIR QRISSFETFG SSQLPDKGAQ RLSLQPSSGE AAKPLGKHEE GRFSGLLGRG AAPTLVPQQP EQVLSSGSPA ASEARDPGVS ESPPPGRQPN QKTLPPGPDP LLRLLSTQAE ESQGPVLKMP SQRARSFPLT RSQSCETKLL DEKTSKLYSI SSQVSSAVMK SLLCLPSSIS CAQTPCIPKE GASPTSSSNE DSAANGSAET SALDTGFSLN LSELREYTEG LTEAKEDDDG DHSSLQSGQS VISLLSSEEL KKLIEEVKVL DEATLKQLDG IHVTILHKEE GAGLGFSLAG GADLENKVIT VHRVFPNGLA SQEGTIQKGN EVLSINGKSL KGTTHHDALA ILRQAREPRQ AVIVTRKLTP EAMPDLNSST DSAASASAAS DVSVESTAEA TVCTVTLEKM SAGLGFSLEG GKGSLHGDKP LTINRIFKGA ASEQSETVQP GDEILQLGGT AMQGLTRFEA WNIIKALPDG PVTIVIRRKS LQSKETTAAG DS
Genular Protein ID: 117545354
Symbol: Q9UME6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9144227
Title: Molecular cloning, sequence, expression, and processing of the interleukin 16 precursor.
PubMed ID: 9144227
Sequence Information:
- Length: 631
- Mass: 66746
- Checksum: 7E5055E5C12147AA
- Sequence:
MDYSFDTTAE DPWVRISDCI KNLFSPIMSE NHGHMPLQPN ASLNEEEGTQ GHPDGTPPKL DTANGTPKVY KSADSSTVKK GPPVAPKPAW FRQSLKGLRN RASDPRGLPD PALSTQPAPA SREHLGSHIR ASSSSSSIRQ RISSFETFGS SQLPDKGAQR LSLQPSSGEA AKPLGKHEEG RFSGLLGRGA APTLVPQQPE QVLSSGSPAA SEARDPGVSE SPPPRRQPNQ KTLPPGPDPL LRLLSTQAEE SQGPVLKMPS QRARSFPLTR SQSCETKLLD EKTSKLYSIS SQVSSAVMKS LLCLPSSISC AQTPCIPKEG ASPTSSSNED SAANGSAETS ALDTGFSLNL SELREYTEGL TEAKEDDDGD HSSLQSGQSV ISLLSSEELK KLIEEVKVLD EATLKQLDGI HVTILHKEEG AGLGFSLAGG ADLENKVITV HRVFPNGLAS QEGTIQKGNE VLSINGKSLK GTTHHDALAI LRQAREPRQA VIVTRKLTPE AMPDLNSSTD SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.