Details for: IMPDH1

Gene ID: 3614

Symbol: IMPDH1

Ensembl ID: ENSG00000106348

Description: inosine monophosphate dehydrogenase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 142.4023
    Cell Significance Index: -22.1500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 80.2308
    Cell Significance Index: -20.3500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 44.5777
    Cell Significance Index: -18.1100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 39.6201
    Cell Significance Index: -20.3800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.3056
    Cell Significance Index: -22.5700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.9759
    Cell Significance Index: -18.6900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.8337
    Cell Significance Index: -23.0200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.7149
    Cell Significance Index: -11.4100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.9791
    Cell Significance Index: -6.5200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 2.0448
    Cell Significance Index: 128.8800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.1926
    Cell Significance Index: 25.4000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.1054
    Cell Significance Index: 20.4300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8415
    Cell Significance Index: 759.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6734
    Cell Significance Index: 109.5300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6174
    Cell Significance Index: 67.1600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5615
    Cell Significance Index: 26.1800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5024
    Cell Significance Index: 32.4200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.4859
    Cell Significance Index: 7.8000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.4604
    Cell Significance Index: 13.5200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4514
    Cell Significance Index: 27.1000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4503
    Cell Significance Index: 23.6500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4045
    Cell Significance Index: 10.8200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2882
    Cell Significance Index: 57.8100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2673
    Cell Significance Index: 7.4700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2646
    Cell Significance Index: 18.3000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2385
    Cell Significance Index: 45.3900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1957
    Cell Significance Index: 35.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1863
    Cell Significance Index: 66.8200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1765
    Cell Significance Index: 24.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1636
    Cell Significance Index: 20.1100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1599
    Cell Significance Index: 87.3400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1408
    Cell Significance Index: 16.6100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1175
    Cell Significance Index: 51.9600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0928
    Cell Significance Index: 2.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0903
    Cell Significance Index: 6.7300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0732
    Cell Significance Index: 5.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0699
    Cell Significance Index: 6.9100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0406
    Cell Significance Index: 2.1100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0394
    Cell Significance Index: 0.4700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0393
    Cell Significance Index: 1.7800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0386
    Cell Significance Index: 4.9900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0372
    Cell Significance Index: 0.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0309
    Cell Significance Index: 0.8900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0309
    Cell Significance Index: 3.9600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0255
    Cell Significance Index: 5.0600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0236
    Cell Significance Index: 32.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0085
    Cell Significance Index: 1.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0023
    Cell Significance Index: 3.5900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -0.9900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0017
    Cell Significance Index: -3.1700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0116
    Cell Significance Index: -8.8100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0194
    Cell Significance Index: -12.3300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0219
    Cell Significance Index: -0.7700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0231
    Cell Significance Index: -16.9500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0239
    Cell Significance Index: -0.4000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0305
    Cell Significance Index: -22.6200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0370
    Cell Significance Index: -20.8900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0371
    Cell Significance Index: -16.8400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0410
    Cell Significance Index: -4.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0425
    Cell Significance Index: -26.5600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0436
    Cell Significance Index: -1.0900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0465
    Cell Significance Index: -1.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0485
    Cell Significance Index: -2.2800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0586
    Cell Significance Index: -16.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0667
    Cell Significance Index: -9.6900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0879
    Cell Significance Index: -1.8400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1021
    Cell Significance Index: -11.9000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1250
    Cell Significance Index: -26.3300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1352
    Cell Significance Index: -15.4900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1389
    Cell Significance Index: -1.5100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1815
    Cell Significance Index: -4.9400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1836
    Cell Significance Index: -4.6900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1842
    Cell Significance Index: -11.3200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1938
    Cell Significance Index: -13.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1952
    Cell Significance Index: -11.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2092
    Cell Significance Index: -21.7900
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.2137
    Cell Significance Index: -2.5900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2237
    Cell Significance Index: -4.6400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2280
    Cell Significance Index: -2.5900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2347
    Cell Significance Index: -18.0100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2444
    Cell Significance Index: -19.3600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2678
    Cell Significance Index: -4.5900
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.2996
    Cell Significance Index: -3.3900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3232
    Cell Significance Index: -18.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3316
    Cell Significance Index: -17.2700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3682
    Cell Significance Index: -7.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3794
    Cell Significance Index: -16.7800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4042
    Cell Significance Index: -10.3900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4419
    Cell Significance Index: -12.6100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4587
    Cell Significance Index: -15.9400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4611
    Cell Significance Index: -17.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4711
    Cell Significance Index: -15.0900
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.4761
    Cell Significance Index: -6.7700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.5043
    Cell Significance Index: -7.6000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5181
    Cell Significance Index: -19.0200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5205
    Cell Significance Index: -14.9200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.5419
    Cell Significance Index: -14.4700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5531
    Cell Significance Index: -16.2900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5817
    Cell Significance Index: -8.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzyme Function:** IMPDH1 is a dehydrogenase enzyme that catalyzes the conversion of inosine monophosphate (IMP) to xanthosine-5'-monophosphate (XMP), a key step in the purine biosynthesis pathway. 2. **Subcellular Location:** IMPDH1 is primarily localized in the cytosol and nucleus of immune cells. 3. **Expression Pattern:** IMPDH1 is highly expressed in various immune cells, including CD14-positive and CD16-positive monocytes, macrophages, dendritic cells, and neutrophils. **Pathways and Functions:** 1. **Purine Biosynthesis:** IMPDH1 is essential for the production of GMP and GTP, which are crucial energy currencies for various cellular processes, including immune cell activation and function. 2. **Immune Cell Activation:** IMPDH1 is involved in the activation of immune cells, including macrophages and dendritic cells, which is critical for the initiation of immune responses. 3. **Antiviral Defense:** IMPDH1 has been implicated in the antiviral defense against SARS-CoV and other viral infections, highlighting its importance in the innate immune response. 4. **Cancer Immune Evasion:** IMPDH1 has been shown to be overexpressed in various types of cancer, suggesting its potential role in cancer immune evasion. **Clinical Significance:** 1. **Infectious Diseases:** IMPDH1 has been implicated in the pathogenesis of various infectious diseases, including SARS-CoV and other viral infections. 2. **Cancer:** IMPDH1 overexpression has been linked to cancer immune evasion and poor prognosis in various types of cancer. 3. **Autoimmune Diseases:** IMPDH1 has been implicated in the pathogenesis of autoimmune diseases, including rheumatoid arthritis and lupus. 4. **Therapeutic Target:** IMPDH1 has been identified as a potential therapeutic target for the treatment of various diseases, including cancer and infectious diseases. In conclusion, IMPDH1 is a crucial enzyme that plays a pivotal role in the immune system, particularly in the purine biosynthesis pathway and immune cell activation. Its dysregulation has been implicated in various diseases, including infectious diseases, cancer, and autoimmune diseases. Further research is needed to fully understand the role of IMPDH1 in human health and disease.

Genular Protein ID: 3649824902

Symbol: IMDH1_HUMAN

Name: IMPDH-I

UniProtKB Accession Codes:

P20839 A4D0Z6 A4D0Z7 A6NDW5 A6NNI6 B3KNP7 B3KVM8 B4DE09 C9JV30 J3KNX8 Q8N194 Q96NU2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CDD 2 CTD 1 ChEBI 20 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 9 DrugCentral 1 EC 1 EMBL 11 EMDB 13 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 18 PDBsum 18 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 4 RefSeq 9 Rhea 1 SABIO-RK 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1969416

Title: Two distinct cDNAs for human IMP dehydrogenase.

PubMed ID: 1969416

DOI: 10.1016/s0021-9258(19)34120-1

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7903306

Title: Characterization of human type I and type II IMP dehydrogenases.

PubMed ID: 7903306

DOI: 10.1016/s0021-9258(19)74247-1

PubMed ID: 15028279

Title: PCR isolation and cloning of novel splice variant mRNAs from known drug target genes.

PubMed ID: 15028279

DOI: 10.1016/j.ygeno.2003.09.023

PubMed ID: 7763314

Title: Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.

PubMed ID: 7763314

DOI: 10.1016/0006-2952(95)00026-v

PubMed ID: 14766016

Title: Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo.

PubMed ID: 14766016

DOI: 10.1042/bj20031585

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 11875049

Title: Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho(-/-) mice.

PubMed ID: 11875049

DOI: 10.1093/hmg/11.5.547

PubMed ID: 11875050

Title: Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa.

PubMed ID: 11875050

DOI: 10.1093/hmg/11.5.559

PubMed ID: 16384941

Title: Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and Leber congenital amaurosis.

PubMed ID: 16384941

DOI: 10.1167/iovs.05-0868

Sequence Information:

  • Length: 514
  • Mass: 55406
  • Checksum: ABAC654A9091BE62
  • Sequence:
    • MADYLISGGT GYVPEDGLTA QQLFASADGL TYNDFLILPG FIDFIADEVD LTSALTRKIT 
LKTPLISSPM DTVTEADMAI AMALMGGIGF IHHNCTPEFQ ANEVRKVKKF EQGFITDPVV 
LSPSHTVGDV LEAKMRHGFS GIPITETGTM GSKLVGIVTS RDIDFLAEKD HTTLLSEVMT 
PRIELVVAPA GVTLKEANEI LQRSKKGKLP IVNDCDELVA IIARTDLKKN RDYPLASKDS 
QKQLLCGAAV GTREDDKYRL DLLTQAGVDV IVLDSSQGNS VYQIAMVHYI KQKYPHLQVI 
GGNVVTAAQA KNLIDAGVDG LRVGMGCGSI CITQEVMACG RPQGTAVYKV AEYARRFGVP 
IIADGGIQTV GHVVKALALG ASTVMMGSLL AATTEAPGEY FFSDGVRLKK YRGMGSLDAM 
EKSSSSQKRY FSEGDKVKIA QGVSGSIQDK GSIQKFVPYL IAGIQHGCQD IGARSLSVLR 
SMMYSGELKF EKRTMSAQIE GGVHGLHSYE KRLY

Genular Protein ID: 876879802

Symbol: B3KRZ3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KRZ3

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 18 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 7 Gene3D 1 HAMAP 1 HAMAP-Rule 1 InterPro 5 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 Rhea 1 RuleBase 2 SMART 2 SUPFAM 1 UniPathway 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 522
  • Mass: 56366
  • Checksum: 539CB029594FA082
  • Sequence:
    • MDRLRRASMA DYLISGGTGY VPEDGLTAQQ LFASADGLTY NDFLILPGFI DFIADEVDLT 
SALTRKITLK TPLISSPMDT VTEADMAIAM ALMGGIGFIH HNCTPEFQAN EVRKVKKFEQ 
GFITDPVVLS PSHTVGDVLE AKMRHGFSGI PITETGTMGS KLVGIVTSRD IDFLAEKDHT 
TLLSEVMTPR IELVVAPAGV TLKEANEILQ RSKKGKLPIV NDCDELVAII ARTDLKKNRD 
YPLASKDSQK QLLCGAAVGT REDDKYRLDL LTQAGVDVIV LDSSQGNSVY QIAMVHYIKQ 
KYPHLQVIGG NVVTAAQAKN LIDAGVDGLR VGMGCGSICI TQEVMACGRP QGTAVYKVAE 
YARRFGVPII ADGGIQTVGH VVKALALGAS TVMMGSLLAA TTEAPGEYFF SDGVRLKKYR 
GMGSLDAMEK SSSSQKRYFS EGDKVKIAQG VSGSIQDKGS IQKFVPHLIA GIQHGCQDIG 
ARSLSVLRSM MYSGELKFEK RTMSAQIEGG VHGLHSYEKR LY

Genular Protein ID: 674284723

Symbol: Q6ZNB1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ZNB1

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 18 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 7 Gene3D 1 HAMAP 1 HAMAP-Rule 1 InterPro 5 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PROSITE 3 PROSITE-ProRule 1 Pfam 2 RefSeq 1 Rhea 1 RuleBase 2 SAM 1 SMART 2 SUPFAM 1 UniPathway 1

Sequence Information:

  • Length: 530
  • Mass: 57050
  • Checksum: F4517075D4DF140E
  • Sequence:
    • MEGPLTPPPL QGGGAAAVPE PGARQHPGHE TAAQRYSARL LQAGYEPESD FLILPGFIDF 
IADEVDLTSA LTRKITLKTP LISSPMDTVT EADMAFAMAL MGGIGFIHHN CTPEFQANEV 
RKVKKFEQGF ITDPVVLSPS HTVGDVLEAK MRHGFSGIPI TETGTMGSKL VGIVTSRDID 
FLAEKDHTTL LSEVMTPRIE LVVAPAGVTL KEANEILQRS KKGKLPIVND CDELVAIIAR 
TDLKKNRDYP LASKDSQKQL LCGAAVGTRE DDKYRLDLLT QAGVDVIVLD SSQGNSVYQI 
AMVHYIKQKY PHLQVIGGNV VTAAQAKNLI DAGVDGLRVG MGCGSICITQ EVMACGRPQG 
TAVYKVAEYA RRFGVPIIAD GGIQTVGHVV KALALGASTV MMGSLLAATT EAPGEYFFSD 
GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI 
QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.