Details for: IRF5

Gene ID: 3663

Symbol: IRF5

Ensembl ID: ENSG00000128604

Description: interferon regulatory factor 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 37.1596
    Cell Significance Index: -5.7800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 14.7690
    Cell Significance Index: -6.0000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 12.6170
    Cell Significance Index: -6.4900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 10.0929
    Cell Significance Index: -2.5600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 6.3054
    Cell Significance Index: -6.0200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.6920
    Cell Significance Index: -5.7900
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.9302
    Cell Significance Index: 12.8100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.6829
    Cell Significance Index: 31.1100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.4977
    Cell Significance Index: -5.9100
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 1.2469
    Cell Significance Index: 7.9600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.0408
    Cell Significance Index: 26.5900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.9915
    Cell Significance Index: -2.1700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6521
    Cell Significance Index: 124.1000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.5540
    Cell Significance Index: 14.8200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4168
    Cell Significance Index: 41.2400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3733
    Cell Significance Index: 7.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3414
    Cell Significance Index: 308.2700
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.3381
    Cell Significance Index: 3.9300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.3062
    Cell Significance Index: 2.8200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2319
    Cell Significance Index: 6.8100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2274
    Cell Significance Index: 24.7300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2191
    Cell Significance Index: 35.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2080
    Cell Significance Index: 24.5300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2001
    Cell Significance Index: 12.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1708
    Cell Significance Index: 8.8700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1473
    Cell Significance Index: 2.0100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1353
    Cell Significance Index: 24.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1198
    Cell Significance Index: 8.2900
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.1167
    Cell Significance Index: 0.9500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1088
    Cell Significance Index: 7.0200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0886
    Cell Significance Index: 1.9400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0738
    Cell Significance Index: 9.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0592
    Cell Significance Index: 32.3200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0361
    Cell Significance Index: 1.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0346
    Cell Significance Index: 0.7500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0146
    Cell Significance Index: 0.6800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0096
    Cell Significance Index: 1.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0070
    Cell Significance Index: 0.7200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0040
    Cell Significance Index: 1.7700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0034
    Cell Significance Index: 0.1200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0020
    Cell Significance Index: 0.0300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0020
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0018
    Cell Significance Index: -3.3600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0022
    Cell Significance Index: -0.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0035
    Cell Significance Index: -6.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0041
    Cell Significance Index: -6.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0046
    Cell Significance Index: -1.6600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0048
    Cell Significance Index: -6.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0050
    Cell Significance Index: -0.7200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0061
    Cell Significance Index: -1.2200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0063
    Cell Significance Index: -4.0300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0071
    Cell Significance Index: -5.4000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0073
    Cell Significance Index: -1.2500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0078
    Cell Significance Index: -5.7300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0078
    Cell Significance Index: -5.7800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0098
    Cell Significance Index: -6.1400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0102
    Cell Significance Index: -5.7600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0129
    Cell Significance Index: -0.3600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0131
    Cell Significance Index: -5.9500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0150
    Cell Significance Index: -4.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0213
    Cell Significance Index: -1.0800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0238
    Cell Significance Index: -2.7700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0244
    Cell Significance Index: -2.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0253
    Cell Significance Index: -3.2400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0297
    Cell Significance Index: -6.2600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0365
    Cell Significance Index: -5.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0373
    Cell Significance Index: -4.8200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0387
    Cell Significance Index: -2.3700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0439
    Cell Significance Index: -0.9100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0471
    Cell Significance Index: -1.9300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0529
    Cell Significance Index: -3.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0626
    Cell Significance Index: -2.9400
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.0708
    Cell Significance Index: -0.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0710
    Cell Significance Index: -5.2900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0720
    Cell Significance Index: -5.5200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0783
    Cell Significance Index: -6.2000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0850
    Cell Significance Index: -5.3600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0879
    Cell Significance Index: -5.9100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0892
    Cell Significance Index: -1.2700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0906
    Cell Significance Index: -1.3300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0926
    Cell Significance Index: -2.5200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0954
    Cell Significance Index: -4.1500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0998
    Cell Significance Index: -5.2000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1017
    Cell Significance Index: -6.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1049
    Cell Significance Index: -3.3600
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1054
    Cell Significance Index: -1.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1080
    Cell Significance Index: -6.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1108
    Cell Significance Index: -5.8200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1128
    Cell Significance Index: -0.9200
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.1254
    Cell Significance Index: -1.7400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1261
    Cell Significance Index: -2.4700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1273
    Cell Significance Index: -3.7500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1320
    Cell Significance Index: -1.8900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1354
    Cell Significance Index: -4.9700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1364
    Cell Significance Index: -4.7800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1366
    Cell Significance Index: -6.0400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1532
    Cell Significance Index: -4.8800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1592
    Cell Significance Index: -6.0300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1595
    Cell Significance Index: -5.2200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1597
    Cell Significance Index: -4.2800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IRF5 is a transcription factor that belongs to the interferon regulatory factor family. It is characterized by its ability to bind to specific DNA sequences and regulate the expression of target genes involved in immune responses. Key features of IRF5 include: 1. **DNA-binding specificity**: IRF5 exhibits a high degree of specificity for binding to GC-rich motifs, which are commonly found in promoters of interferon and cytokine genes. 2. **Transcriptional activation**: IRF5 acts as a transcriptional activator, promoting the expression of target genes involved in immune responses. 3. **Interferon signaling**: IRF5 is a key mediator of interferon signaling, regulating the production of type I and type II IFNs, which are essential for antiviral and immunomodulatory responses. 4. **Cytokine regulation**: IRF5 also regulates the production of cytokines, including IL-12, which is critical for the induction of Th1 responses. **Pathways and Functions** IRF5 is involved in several key pathways and processes, including: 1. **Interferon signaling pathway**: IRF5 mediates the transcription of interferons, which induce antiviral and immunomodulatory effects. 2. **Cytokine-mediated signaling pathway**: IRF5 regulates the production of cytokines, including IL-12, which is critical for the induction of Th1 responses. 3. **Innate immune response**: IRF5 plays a crucial role in the regulation of innate immune responses, including the production of type I and type II IFNs. 4. **Adaptive immune response**: IRF5 also regulates the production of cytokines involved in the adaptive immune response, including IL-12. **Clinical Significance** Dysregulation of IRF5 has been implicated in several autoimmune and inflammatory disorders, including: 1. **Systemic lupus erythematosus (SLE)**: IRF5 has been shown to be overexpressed in patients with SLE, and its dysregulation contributes to the development of autoimmune responses. 2. **Rheumatoid arthritis (RA)**: IRF5 has been implicated in the regulation of cytokine production and immune responses in RA, highlighting its potential as a therapeutic target. 3. **Infectious diseases**: IRF5 plays a crucial role in the regulation of innate immune responses, and its dysregulation can contribute to the development of infectious diseases, such as viral infections and sepsis. 4. **Cancer**: IRF5 has been shown to have a role in the regulation of immune responses in cancer, and its dysregulation can contribute to the development of immunosuppression and tumor progression. In conclusion, IRF5 is a critical transcription factor that plays a pivotal role in regulating immune responses, particularly in the context of viral infections. Its dysregulation has been implicated in several autoimmune and inflammatory disorders, highlighting its potential as a therapeutic target. Further research is needed to fully understand the mechanisms by which IRF5 regulates immune responses and to explore its therapeutic potential.

Genular Protein ID: 2408877754

Symbol: IRF5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11303025

Title: Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes.

PubMed ID: 11303025

DOI: 10.1074/jbc.m101216200

PubMed ID: 15695821

Title: The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.

PubMed ID: 15695821

DOI: 10.1074/jbc.m412584200

PubMed ID: 15805103

Title: Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function.

PubMed ID: 15805103

DOI: 10.1074/jbc.m500543200

PubMed ID: 16642019

Title: A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.

PubMed ID: 16642019

DOI: 10.1038/ng1782

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12138184

Title: Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes.

PubMed ID: 12138184

DOI: 10.1128/mcb.22.16.5721-5740.2002

PubMed ID: 15657875

Title: Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.

PubMed ID: 15657875

DOI: 10.1086/428480

PubMed ID: 15556946

Title: A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.

PubMed ID: 15556946

DOI: 10.1074/jbc.m408452200

PubMed ID: 17599733

Title: Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis.

PubMed ID: 17599733

DOI: 10.1002/art.22704

PubMed ID: 17881657

Title: An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases.

PubMed ID: 17881657

DOI: 10.1093/hmg/ddm259

PubMed ID: 18824541

Title: Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.

PubMed ID: 18824541

DOI: 10.1128/mcb.00662-08

PubMed ID: 22412986

Title: Activation of interferon regulatory factor 5 by site specific phosphorylation.

PubMed ID: 22412986

DOI: 10.1371/journal.pone.0033098

PubMed ID: 25326418

Title: Protein kinase IKKbeta-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.

PubMed ID: 25326418

DOI: 10.1073/pnas.1418399111

PubMed ID: 32433612

Title: TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.

PubMed ID: 32433612

DOI: 10.1038/s41586-020-2282-0

PubMed ID: 33440148

Title: MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells.

PubMed ID: 33440148

DOI: 10.1016/j.celrep.2020.108628

PubMed ID: 18836453

Title: Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.

PubMed ID: 18836453

DOI: 10.1038/nsmb.1496

Sequence Information:

  • Length: 498
  • Mass: 56044
  • Checksum: 01B2ED95C28384E8
  • Sequence:
  • MNQSIPVAPT PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFCIPWRHA TRHGPSQDGD 
    NTIFKAWAKE TGKYTEGVDE ADPAKWKANL RCALNKSRDF RLIYDGPRDM PPQPYKIYEV 
    CSNGPAPTDS QPPEDYSFGA GEEEEEEEEL QRMLPSLSLT EDVKWPPTLQ PPTLRPPTLQ 
    PPTLQPPVVL GPPAPDPSPL APPPGNPAGF RELLSEVLEP GPLPASLPPA GEQLLPDLLI 
    SPHMLPLTDL EIKFQYRGRP PRALTISNPH GCRLFYSQLE ATQEQVELFG PISLEQVRFP 
    SPEDIPSDKQ RFYTNQLLDV LDRGLILQLQ GQDLYAIRLC QCKVFWSGPC ASAHDSCPNP 
    IQREVKTKLF SLEHFLNELI LFQKGQTNTP PPFEIFFCFG EEWPDRKPRE KKLITVQVVP 
    VAARLLLEMF SGELSWSADS IRLQISNPDL KDRMVEQFKE LHHIWQSQQR LQPVAQAPPG 
    AGLGVGQGPW PMHPAGMQ

Genular Protein ID: 58802160

Symbol: A0A0G2USB5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 417
  • Mass: 46816
  • Checksum: 85B233DF3782AD4E
  • Sequence:
  • MNQSIPVAPT PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFCIPWRHA TRHGPSQDGD 
    NTIFKAWAKE TGKYTEGVDE ADPAKWKANL RCALNKSRDF RLIYDGPRDM PPQPYKIYEV 
    CSNGPAPTDS QPPEDYSFGA GEEEEEEEEL QRMLPSLSLT DAVQSGPHMT PYSLLKEDVK 
    WPPTLQPPTL RPPTLQPPTL QPPVVLGPPA PDPSPLAPPP GNPAGFRELL SEVLEPGPLP 
    ASLPPAGEQL LPDLLISPHM LPLTDLEIKF QYRGRPPRAL TISNPHGCRL FYSQLEATQE 
    QVELFGPISL EQVRFPSPED IPSDKQRFYT NQLLDVLDRG LILQLQGQDL YAIRLCQCKV 
    FWSGPCASAH DSCPNPIQRE VKTKLFSLEH FLNELILFQK GQTNTPPPFE IFFCFGE

Genular Protein ID: 2034621736

Symbol: B7Z1M2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 140
  • Mass: 16367
  • Checksum: A94DEF487C1D40DC
  • Sequence:
  • MNQSIPVAPT PPRRVRLKPW LVAQVNSCQY PGLQWVNGEK KLFCIPWRHA TRHGPSQDGD 
    NTIFKAWAKE TGKYTEGVDE ADPAKWKANL RCALNKSRDF RLIYDGPRDM PPQPYKIYET 
    PSPLRITLLV QERRRKKRKR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.