Details for: IRF7

Gene ID: 3665

Symbol: IRF7

Ensembl ID: ENSG00000185507

Description: interferon regulatory factor 7

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.91
    Marker Score: 107079
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.78
    Marker Score: 3468
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 1.77
    Marker Score: 4878
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.55
    Marker Score: 17964.5
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 1.39
    Marker Score: 485
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.38
    Marker Score: 13949
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 1.31
    Marker Score: 298
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 1.28
    Marker Score: 1204
  • Cell Name: plasmacytoid dendritic cell, human (CL0001058)
    Fold Change: 1.24
    Marker Score: 327
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.21
    Marker Score: 12012.5
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.19
    Marker Score: 1951
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.14
    Marker Score: 1932
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 1.13
    Marker Score: 469
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.12
    Marker Score: 1958
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 1.07
    Marker Score: 1284
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 1.07
    Marker Score: 56382
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.04
    Marker Score: 1062
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251662
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 1.03
    Marker Score: 2481
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.02
    Marker Score: 3233
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71682
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47910
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.99
    Marker Score: 677
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 0.99
    Marker Score: 228
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.98
    Marker Score: 13227
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 0.98
    Marker Score: 1445
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30391
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 0.98
    Marker Score: 857
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2393
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.94
    Marker Score: 941
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 0.94
    Marker Score: 798
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 0.94
    Marker Score: 836
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 0.93
    Marker Score: 617
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.93
    Marker Score: 678
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 0.93
    Marker Score: 673
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 475
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 431
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.9
    Marker Score: 1198
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.9
    Marker Score: 350
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.9
    Marker Score: 1570
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2690
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 0.88
    Marker Score: 531
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.88
    Marker Score: 588
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.87
    Marker Score: 551
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.86
    Marker Score: 5221
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 309
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 0.86
    Marker Score: 649
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.86
    Marker Score: 21917
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.85
    Marker Score: 583
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.84
    Marker Score: 4770
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.83
    Marker Score: 446
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.83
    Marker Score: 2061
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 0.82
    Marker Score: 670.5
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 0.81
    Marker Score: 330
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.79
    Marker Score: 956.5
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: 0.79
    Marker Score: 344
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.79
    Marker Score: 539
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.78
    Marker Score: 623
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1263
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.77
    Marker Score: 1904
  • Cell Name: ILC1, human (CL0001077)
    Fold Change: 0.77
    Marker Score: 196
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 0.77
    Marker Score: 452
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.77
    Marker Score: 1134
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.77
    Marker Score: 1988
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 581
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 0.76
    Marker Score: 555
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.76
    Marker Score: 440
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 0.76
    Marker Score: 261
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.75
    Marker Score: 432
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.75
    Marker Score: 3582
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.75
    Marker Score: 299
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: 0.74
    Marker Score: 197
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.74
    Marker Score: 569
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.73
    Marker Score: 2809
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.73
    Marker Score: 356
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 0.73
    Marker Score: 446
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.73
    Marker Score: 2279
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 0.72
    Marker Score: 700
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 0.72
    Marker Score: 623
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.72
    Marker Score: 614
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 373
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.72
    Marker Score: 725
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.72
    Marker Score: 1958
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.72
    Marker Score: 932
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 0.71
    Marker Score: 187
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.71
    Marker Score: 251
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 0.71
    Marker Score: 697
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 0.71
    Marker Score: 1796
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 0.7
    Marker Score: 153
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.7
    Marker Score: 6143
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.7
    Marker Score: 626
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.7
    Marker Score: 23740
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7
    Marker Score: 2919
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 0.7
    Marker Score: 2982
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.69
    Marker Score: 460.5
  • Cell Name: T follicular helper cell (CL0002038)
    Fold Change: 0.69
    Marker Score: 575
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.69
    Marker Score: 613
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.68
    Marker Score: 334
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 175
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 0.68
    Marker Score: 490

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Other Information

**Key characteristics:** * IRF7 is a protein of the interferon regulatory factor 7 (IRF) family. * It is a key regulator of type I interferon production. * It is expressed in a variety of immune cells, including monocytes, dendritic cells, and macrophages. * It is involved in the regulation of inflammation, cell differentiation, and apoptosis. **Pathways and functions:** * IRF7 is a key regulator of type I interferon production. * It binds to the Toll-like receptor 3 (tlr3) and Toll-like receptor 4 (tlr4) receptors, which are expressed on various immune cells. * Upon binding to these receptors, IRF7 triggers the activation of the innate immune system. * IRF7 also binds to the TLR7/8 receptor, which is expressed on dendritic cells and macrophages. * Activation of IRF7 by TLR7/8 leads to the production of type I interferons, which have anti-inflammatory effects. **Clinical significance:** * Mutations in the IRF7 gene have been linked to several human diseases, including rheumatoid arthritis, lupus, and tuberculosis. * IRF7 is a potential therapeutic target for these diseases. **Conclusion:** IRF7 is a key regulator of the immune response by modulating the production of type I interferons. Its expression and activity are tightly controlled by various factors, including cytokines, hormones, and cellular signals. Dysregulation of IRF7 signaling has been linked to several human diseases, suggesting that it may be a promising target for therapeutic intervention.

Genular Protein ID: 3100312569

Symbol: IRF7_HUMAN

Name: Interferon regulatory factor 7

UniProtKB Accession Codes:

Q92985 B9EGL3 O00331 O00332 O00333 O75924 Q9UE79

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EPD 1 Ensembl 12 ExpressionAtlas 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 9 RefSeq 5 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9315633

Title: IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency.

PubMed ID: 9315633

DOI: 10.1128/mcb.17.10.5748

PubMed ID: 9786932

Title: Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes.

PubMed ID: 9786932

DOI: 10.1074/jbc.273.44.29210

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11073981

Title: Phosphorylation-induced dimerization of interferon regulatory factor 7 unmasks DNA binding and a bipartite transactivation domain.

PubMed ID: 11073981

DOI: 10.1128/mcb.20.23.8803-8814.2000

PubMed ID: 11124948

Title: IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein.

PubMed ID: 11124948

DOI: 10.1074/jbc.m008717200

PubMed ID: 11314014

Title: HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators.

PubMed ID: 11314014

DOI: 10.1038/sj.onc.1204163

PubMed ID: 12374802

Title: Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding.

PubMed ID: 12374802

DOI: 10.1074/jbc.m207484200

PubMed ID: 11846980

Title: Structure and function of IRF-7.

PubMed ID: 11846980

DOI: 10.1089/107999002753452700

PubMed ID: 11943871

Title: A Kaposi's sarcoma-associated herpesviral protein inhibits virus-mediated induction of type I interferon by blocking IRF-7 phosphorylation and nuclear accumulation.

PubMed ID: 11943871

DOI: 10.1073/pnas.082420599

PubMed ID: 14517278

Title: LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

PubMed ID: 14517278

DOI: 10.1084/jem.20031023

PubMed ID: 14739303

Title: Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways.

PubMed ID: 14739303

DOI: 10.1074/jbc.m311629200

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 15367631

Title: Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.

PubMed ID: 15367631

DOI: 10.1128/jvi.78.19.10636-10649.2004

PubMed ID: 15492225

Title: Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.

PubMed ID: 15492225

DOI: 10.1073/pnas.0406933101

PubMed ID: 15361868

Title: Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6.

PubMed ID: 15361868

DOI: 10.1038/ni1118

PubMed ID: 15767370

Title: Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

PubMed ID: 15767370

DOI: 10.1084/jem.20042372

PubMed ID: 16846591

Title: Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages.

PubMed ID: 16846591

DOI: 10.1016/j.bcp.2006.06.002

PubMed ID: 16979567

Title: Type I interferon gene induction by the interferon regulatory factor family of transcription factors.

PubMed ID: 16979567

DOI: 10.1016/j.immuni.2006.08.009

PubMed ID: 17404045

Title: IRF-7: new role in the regulation of genes involved in adaptive immunity.

PubMed ID: 17404045

DOI: 10.1196/annals.1397.036

PubMed ID: 17301153

Title: Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7.

PubMed ID: 17301153

DOI: 10.1128/jvi.02498-06

PubMed ID: 19017798

Title: IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3.

PubMed ID: 19017798

DOI: 10.1073/pnas.0809933105

PubMed ID: 18987133

Title: Epstein-Barr virus LF2: an antagonist to type I interferon.

PubMed ID: 18987133

DOI: 10.1128/jvi.00602-08

PubMed ID: 19557165

Title: Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery.

PubMed ID: 19557165

DOI: 10.1371/journal.ppat.1000493

PubMed ID: 20049431

Title: Regulation of immunity and oncogenesis by the IRF transcription factor family.

PubMed ID: 20049431

DOI: 10.1007/s00262-009-0804-6

PubMed ID: 21167755

Title: The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3.

PubMed ID: 21167755

DOI: 10.1016/j.immuni.2010.11.027

PubMed ID: 21490621

Title: IRF7: activation, regulation, modification and function.

PubMed ID: 21490621

DOI: 10.1038/gene.2011.21

PubMed ID: 21940674

Title: Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.

PubMed ID: 21940674

DOI: 10.4049/jimmunol.1101704

PubMed ID: 25907537

Title: TRIM35 negatively regulates TLR7- and TLR9-mediated type I interferon production by targeting IRF7.

PubMed ID: 25907537

DOI: 10.1016/j.febslet.2015.04.019

PubMed ID: 26608321

Title: 3C Protease of Enterovirus D68 Inhibits Cellular Defense Mediated by Interferon Regulatory Factor 7.

PubMed ID: 26608321

DOI: 10.1128/jvi.02395-15

PubMed ID: 28768861

Title: Positive and Negative Regulation of Type I Interferons by the Human T Cell Leukemia Virus Antisense Protein HBZ.

PubMed ID: 28768861

DOI: 10.1128/jvi.00853-17

PubMed ID: 28768858

Title: Human Metapneumovirus M2-2 Protein Acts as a Negative Regulator of Alpha Interferon Production by Plasmacytoid Dendritic Cells.

PubMed ID: 28768858

DOI: 10.1128/jvi.00579-17

PubMed ID: 23175366

Title: Cleavage of interferon regulatory factor 7 by enterovirus 71 3C suppresses cellular responses.

PubMed ID: 23175366

DOI: 10.1128/jvi.01855-12

PubMed ID: 28342865

Title: KSHV-encoded viral interferon regulatory factor 4 (vIRF4) interacts with IRF7 and inhibits interferon alpha production.

PubMed ID: 28342865

DOI: 10.1016/j.bbrc.2017.03.101

PubMed ID: 29427864

Title: Seneca Valley Virus 3Cpro abrogates the IRF3- and IRF7-mediated innate immune response by degrading IRF3 and IRF7.

PubMed ID: 29427864

DOI: 10.1016/j.virol.2018.01.028

PubMed ID: 30598516

Title: Suppression of the IFN-alpha and -beta Induction through Sequestering IRF7 into Viral Inclusion Bodies by Nonstructural Protein NSs in Severe Fever with Thrombocytopenia Syndrome Bunyavirus Infection.

PubMed ID: 30598516

DOI: 10.4049/jimmunol.1800576

PubMed ID: 35792897

Title: E3 ubiquitin ligase NEURL3 promotes innate antiviral response through catalyzing K63-linked ubiquitination of IRF7.

PubMed ID: 35792897

DOI: 10.1096/fj.202200316r

PubMed ID: 17574024

Title: An atomic model of the interferon-beta enhanceosome.

PubMed ID: 17574024

DOI: 10.1016/j.cell.2007.05.019

PubMed ID: 25814066

Title: Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency.

PubMed ID: 25814066

DOI: 10.1126/science.aaa1578

PubMed ID: 32972995

Title: Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

PubMed ID: 32972995

DOI: 10.1126/science.abd4570

Sequence Information:

  • Length: 503
  • Mass: 54278
  • Checksum: 9863C147514652DE
  • Sequence:
    • MALAPERAAP RVLFGEWLLG EISSGCYEGL QWLDEARTCF RVPWKHFARK DLSEADARIF 
KAWAVARGRW PPSSRGGGPP PEAETAERAG WKTNFRCALR STRRFVMLRD NSGDPADPHK 
VYALSRELCW REGPGTDQTE AEAPAAVPPP QGGPPGPFLA HTHAGLQAPG PLPAPAGDKG 
DLLLQAVQQS CLADHLLTAS WGADPVPTKA PGEGQEGLPL TGACAGGPGL PAGELYGWAV 
ETTPSPGPQP AALTTGEAAA PESPHQAEPY LSPSPSACTA VQEPSPGALD VTIMYKGRTV 
LQKVVGHPSC TFLYGPPDPA VRATDPQQVA FPSPAELPDQ KQLRYTEELL RHVAPGLHLE 
LRGPQLWARR MGKCKVYWEV GGPPGSASPS TPACLLPRNC DTPIFDFRVF FQELVEFRAR 
QRRGSPRYTI YLGFGQDLSA GRPKEKSLVL VKLEPWLCRV HLEGTQREGV SSLDSSSLSL 
CLSSANSLYD DIECFLMELE QPA

Genular Protein ID: 3890565348

Symbol: M9RSF4_HUMAN

Name: N/A

UniProtKB Accession Codes:

M9RSF4

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 EPD 1 Ensembl 3 GO 5 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 487
  • Mass: 52817
  • Checksum: 10E6D498EC01F43C
  • Sequence:
    • MPVPERPAAG PDSPRPGTRR AAPRVLFGEW LLGEISSGCY EGLQWLDEAR TCFRVPWKHF 
ARKDLSEADA RIFKAWAVAR GRWPPSSRGG GPPPEAETAE RAGWKTNFRC ALRSTRRFVM 
LRDNSGDPAD PHKVYALSRE LCWREGPGTD QTEAEAPAAV PPPQGGPPGP FLAHTHAGLQ 
APGPLPAPAG DKGDLLLQAV QQSCLADHLL TASWGADPVP TKAPGEGQEG LPLTGACAGG 
EAAAPESPHQ AEPYLSPSPS ACTAVQEPSP GALDVTIMYK GRTVLQKVVG HPSCTFLYGP 
PDPAVRATDP QQVAFPSPAE LPDQKQLRYT EELLRHVAPG LHLELRGPQL WARRMGKCKV 
YWEVGGPPGS ASPSTPACLL PRNCDTPIFD FRVFFQELVE FRARQRRGSP RYTIYLGFGQ 
DLSAGRPKEK SLVLVKLEPW LCRVHLEGTQ REGVSSLDSS SLSLCLSSAN SLYDDIECFL 
MELEQPA

Genular Protein ID: 1506306157

Symbol: B4E1B1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E1B1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 3 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 1 SMART 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 210
  • Mass: 23592
  • Checksum: 45895671CEAA18F5
  • Sequence:
    • MYKGRTVLQK VVGHPSCTFL YGPPDPAVRA TDPQQVAFPS PAELPDQKQL RYTEELLRHV 
APGLHLELRG PQLWARRMGK CKVYWEVGGP PGSASPSTPA CLLPRNCDTP IFDFRVFFQE 
LVEFRARQRR GSPRYTIYLG FGQDLSAGRP KEKSLVLVKL EPWLCRVHLE GTQREGVSSL 
DSSSLSLCLS SANSLYDDIE CFLMELEQPA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.