Details for: ITGA1
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 4.49
Marker Score: 79,683 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 3.66
Marker Score: 3,488 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 3.59
Marker Score: 6,914 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 3.38
Marker Score: 4,205 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 3.05
Marker Score: 1,696 - Cell Name: intraepithelial lymphocyte (CL0002496)
Fold Change: 2.73
Marker Score: 3,036 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.67
Marker Score: 1,445 - Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 2.66
Marker Score: 3,845 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.55
Marker Score: 1,525 - Cell Name: hepatoblast (CL0005026)
Fold Change: 2.23
Marker Score: 7,308 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.15
Marker Score: 814 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.09
Marker Score: 4,909 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 2.08
Marker Score: 1,482 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.99
Marker Score: 2,291 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 1.96
Marker Score: 4,972 - Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
Fold Change: 1.75
Marker Score: 1,267 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 1.74
Marker Score: 15,252 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.73
Marker Score: 541 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.68
Marker Score: 632 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.64
Marker Score: 8,797 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.6
Marker Score: 10,291 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.57
Marker Score: 6,772 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.55
Marker Score: 2,915 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.55
Marker Score: 1,658 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.52
Marker Score: 553 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.51
Marker Score: 2,198 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,326 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.46
Marker Score: 3,444 - Cell Name: pericyte (CL0000669)
Fold Change: 1.43
Marker Score: 837 - Cell Name: muscle cell (CL0000187)
Fold Change: 1.35
Marker Score: 383 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 1.35
Marker Score: 1,849 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.34
Marker Score: 3,707 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 1.32
Marker Score: 1,418 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 1.3
Marker Score: 856 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.27
Marker Score: 322 - Cell Name: natural T-regulatory cell (CL0000903)
Fold Change: 1.26
Marker Score: 648 - Cell Name: podocyte (CL0000653)
Fold Change: 1.25
Marker Score: 463 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.25
Marker Score: 1,065 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.22
Marker Score: 24,338 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.22
Marker Score: 2,473 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.18
Marker Score: 305 - Cell Name: neural cell (CL0002319)
Fold Change: 1.15
Marker Score: 556 - Cell Name: memory T cell (CL0000813)
Fold Change: 1.13
Marker Score: 484 - Cell Name: glomerular endothelial cell (CL0002188)
Fold Change: 1.12
Marker Score: 285 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.12
Marker Score: 674 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.09
Marker Score: 1,174 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.08
Marker Score: 721 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.08
Marker Score: 972 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.07
Marker Score: 1,503 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.07
Marker Score: 16,688 - Cell Name: fat cell (CL0000136)
Fold Change: 1.06
Marker Score: 591 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.05
Marker Score: 1,986 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251,724 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.04
Marker Score: 35,238 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.02
Marker Score: 962 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 1.01
Marker Score: 236 - Cell Name: hepatocyte (CL0000182)
Fold Change: 1.01
Marker Score: 688 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1
Marker Score: 1,212 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,748 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1
Marker Score: 315 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 47,973 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.99
Marker Score: 519 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.98
Marker Score: 2,154 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,401 - Cell Name: Schwann cell (CL0002573)
Fold Change: 0.97
Marker Score: 337 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: 0.97
Marker Score: 2,539 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.96
Marker Score: 3,982 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 493 - Cell Name: T-helper 1 cell (CL0000545)
Fold Change: 0.95
Marker Score: 371 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.95
Marker Score: 448 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,406 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 0.94
Marker Score: 291 - Cell Name: endocardial cell (CL0002350)
Fold Change: 0.92
Marker Score: 519 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 0.91
Marker Score: 1,187 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,719 - Cell Name: tracheobronchial smooth muscle cell (CL0019019)
Fold Change: 0.91
Marker Score: 266 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.9
Marker Score: 289 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.88
Marker Score: 317 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.88
Marker Score: 5,288 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.87
Marker Score: 230 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,295 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.86
Marker Score: 412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.86
Marker Score: 4,886 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.85
Marker Score: 332 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.83
Marker Score: 1,008 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.83
Marker Score: 524 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 0.82
Marker Score: 200 - Cell Name: mature T cell (CL0002419)
Fold Change: 0.82
Marker Score: 8,146 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.82
Marker Score: 399 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.82
Marker Score: 306 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.82
Marker Score: 1,630 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 0.82
Marker Score: 737 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.82
Marker Score: 475 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 0.81
Marker Score: 337 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.81
Marker Score: 401 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.81
Marker Score: 616 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.81
Marker Score: 323 - Cell Name: bronchial smooth muscle cell (CL0002598)
Fold Change: 0.8
Marker Score: 227 - Cell Name: exhausted T cell (CL0011025)
Fold Change: 0.8
Marker Score: 462 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.79
Marker Score: 453
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 389744936
Symbol: ITA1_HUMAN
Name: Integrin alpha-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8428973
Title: Expression of native and truncated forms of the human integrin alpha 1 subunit.
PubMed ID: 8428973
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 15592458
Title: Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.
PubMed ID: 15592458
DOI: 10.1038/ncb1209
PubMed ID: 16754960
Title: Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.
PubMed ID: 16754960
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 10455165
Title: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM.
PubMed ID: 10455165
PubMed ID: 14660600
Title: Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1.
PubMed ID: 14660600
Sequence Information:
- Length: 1179
- Mass: 130848
- Checksum: 1A86F30FD916C845
- Sequence:
MAPRPRARPG VAVACCWLLT VVLRCCVSFN VDVKNSMTFS GPVEDMFGYT VQQYENEEGK WVLIGSPLVG QPKNRTGDVY KCPVGRGESL PCVKLDLPVN TSIPNVTEVK ENMTFGSTLV TNPNGGFLAC GPLYAYRCGH LHYTTGICSD VSPTFQVVNS IAPVQECSTQ LDIVIVLDGS NSIYPWDSVT AFLNDLLERM DIGPKQTQVG IVQYGENVTH EFNLNKYSST EEVLVAAKKI VQRGGRQTMT ALGIDTARKE AFTEARGARR GVKKVMVIVT DGESHDNHRL KKVIQDCEDE NIQRFSIAIL GSYNRGNLST EKFVEEIKSI ASEPTEKHFF NVSDELALVT IVKTLGERIF ALEATADQSA ASFEMEMSQT GFSAHYSQDW VMLGAVGAYD WNGTVVMQKA SQIIIPRNTT FNVESTKKNE PLASYLGYTV NSATASSGDV LYIAGQPRYN HTGQVIIYRM EDGNIKILQT LSGEQIGSYF GSILTTTDID KDSNTDILLV GAPMYMGTEK EEQGKVYVYA LNQTRFEYQM SLEPIKQTCC SSRQHNSCTT ENKNEPCGAR FGTAIAAVKD LNLDGFNDIV IGAPLEDDHG GAVYIYHGSG KTIRKEYAQR IPSGGDGKTL KFFGQSIHGE MDLNGDGLTD VTIGGLGGAA LFWSRDVAVV KVTMNFEPNK VNIQKKNCHM EGKETVCINA TVCFDVKLKS KEDTIYEADL QYRVTLDSLR QISRSFFSGT QERKVQRNIT VRKSECTKHS FYMLDKHDFQ DSVRITLDFN LTDPENGPVL DDSLPNSVHE YIPFAKDCGN KEKCISDLSL HVATTEKDLL IVRSQNDKFN VSLTVKNTKD SAYNTRTIVH YSPNLVFSGI EAIQKDSCES NHNITCKVGY PFLRRGEMVT FKILFQFNTS YLMENVTIYL SATSDSEEPP ETLSDNVVNI SIPVKYEVGL QFYSSASEYH ISIAANETVP EVINSTEDIG NEINIFYLIR KSGSFPMPEL KLSISFPNMT SNGYPVLYPT GLSSSENANC RPHIFEDPFS INSGKKMTTS TDHLKRGTIL DCNTCKFATI TCNLTSSDIS QVNVSLILWK PTFIKSYFSS LNLTIRGELR SENASLVLSS SNQKRELAIQ ISKDGLPGRV PLWVILLSAF AGLLLLMLLI LALWKIGFFK RPLKKKMEK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.