Details for: ITIH4

Gene ID: 3700

Symbol: ITIH4

Ensembl ID: ENSG00000055955

Description: inter-alpha-trypsin inhibitor heavy chain 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 31.1164
    Cell Significance Index: -4.8400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 17.9780
    Cell Significance Index: -4.5600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 3.9174
    Cell Significance Index: -4.8300
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 1.3116
    Cell Significance Index: 3.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.4721
    Cell Significance Index: 15.1200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4501
    Cell Significance Index: 9.8600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4173
    Cell Significance Index: 83.7100
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.4143
    Cell Significance Index: 6.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3671
    Cell Significance Index: 13.9000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3606
    Cell Significance Index: 15.9500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.2918
    Cell Significance Index: 7.1200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2915
    Cell Significance Index: 3.6200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2861
    Cell Significance Index: 4.8200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2688
    Cell Significance Index: 2.4800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2430
    Cell Significance Index: 46.2400
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.1931
    Cell Significance Index: 2.7100
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.1875
    Cell Significance Index: 2.1600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1726
    Cell Significance Index: 4.6300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1464
    Cell Significance Index: 52.5000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1373
    Cell Significance Index: 3.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1357
    Cell Significance Index: 13.4300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.1264
    Cell Significance Index: 1.8700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1242
    Cell Significance Index: 112.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0851
    Cell Significance Index: 4.4200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0658
    Cell Significance Index: 10.7100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0618
    Cell Significance Index: 1.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0613
    Cell Significance Index: 4.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0590
    Cell Significance Index: 6.4200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0552
    Cell Significance Index: 10.9500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0446
    Cell Significance Index: 0.7500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0419
    Cell Significance Index: 0.6900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0376
    Cell Significance Index: 2.2600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0297
    Cell Significance Index: 1.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0238
    Cell Significance Index: 4.2900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0162
    Cell Significance Index: 0.3500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0120
    Cell Significance Index: 0.3000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0107
    Cell Significance Index: 0.7400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0101
    Cell Significance Index: 7.0100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0014
    Cell Significance Index: 0.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0014
    Cell Significance Index: 0.6000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0007
    Cell Significance Index: 1.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0004
    Cell Significance Index: -0.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0010
    Cell Significance Index: -1.8500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0015
    Cell Significance Index: -2.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0018
    Cell Significance Index: -0.3100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0033
    Cell Significance Index: -1.5000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0040
    Cell Significance Index: -2.5100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0041
    Cell Significance Index: -0.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0046
    Cell Significance Index: -2.4900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0048
    Cell Significance Index: -0.6600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0054
    Cell Significance Index: -3.9300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0054
    Cell Significance Index: -4.0000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0066
    Cell Significance Index: -5.0000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0073
    Cell Significance Index: -4.1400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0098
    Cell Significance Index: -2.8200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0099
    Cell Significance Index: -0.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0104
    Cell Significance Index: -0.4700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0105
    Cell Significance Index: -1.3400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0107
    Cell Significance Index: -1.5500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0109
    Cell Significance Index: -0.7300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0135
    Cell Significance Index: -1.5700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0146
    Cell Significance Index: -0.3100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0154
    Cell Significance Index: -0.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0222
    Cell Significance Index: -0.4800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0235
    Cell Significance Index: -4.9500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0265
    Cell Significance Index: -2.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0287
    Cell Significance Index: -3.2900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0293
    Cell Significance Index: -0.4200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0324
    Cell Significance Index: -1.5100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0341
    Cell Significance Index: -1.7900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0351
    Cell Significance Index: -4.5400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0352
    Cell Significance Index: -0.5300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0369
    Cell Significance Index: -4.3600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0372
    Cell Significance Index: -2.0900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0399
    Cell Significance Index: -2.0100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0401
    Cell Significance Index: -2.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0457
    Cell Significance Index: -4.7600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0516
    Cell Significance Index: -1.0700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0518
    Cell Significance Index: -1.6500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0525
    Cell Significance Index: -3.7100
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.0528
    Cell Significance Index: -0.7900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0556
    Cell Significance Index: -1.1000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0567
    Cell Significance Index: -0.9800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0568
    Cell Significance Index: -4.2300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0579
    Cell Significance Index: -2.5200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0583
    Cell Significance Index: -1.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0589
    Cell Significance Index: -2.7700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0604
    Cell Significance Index: -4.7800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0611
    Cell Significance Index: -1.3200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0621
    Cell Significance Index: -1.4900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0626
    Cell Significance Index: -2.0500
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.0679
    Cell Significance Index: -0.5700
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0688
    Cell Significance Index: -0.9000
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: -0.0721
    Cell Significance Index: -0.4200
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.0730
    Cell Significance Index: -0.2800
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0744
    Cell Significance Index: -1.2000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0783
    Cell Significance Index: -4.0800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0791
    Cell Significance Index: -2.7700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0820
    Cell Significance Index: -2.3400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0938
    Cell Significance Index: -1.1700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ITIH4 is a member of the inter-alpha-trypsin inhibitor family, characterized by its ability to inhibit serine-type endopeptidases. The heavy chain of ITIH4 (ITIH4_HUMAN) is the primary functional unit, interacting with the light chain to form a heterodimeric complex. This complex exhibits anti-inflammatory properties by regulating the activity of proteases involved in inflammation and tissue remodeling. ITIH4 is highly expressed in cells involved in immune responses, including epithelial cells, stem cells, and immune cells such as early T lineage precursors. **Pathways and Functions:** ITIH4 is involved in several key pathways, including: 1. **Acute-phase response:** ITIH4 regulates the expression of acute-phase proteins, modulating the inflammatory response to tissue damage or infection. 2. **Hemostasis:** ITIH4 inhibits proteases involved in blood coagulation, maintaining the balance between clotting and bleeding. 3. **Cell signaling:** ITIH4 interacts with various signaling molecules, modulating cell proliferation, differentiation, and survival. 4. **Extracellular matrix remodeling:** ITIH4 regulates the activity of proteases involved in matrix remodeling, influencing tissue repair and fibrosis. **Clinical Significance:** ITIH4 dysregulation has been implicated in various diseases, including: 1. **Inflammatory disorders:** ITIH4 deficiency or dysfunction has been linked to increased inflammation and tissue damage in conditions such as arthritis, atherosclerosis, and inflammatory bowel disease. 2. **Cancer:** ITIH4 expression is altered in various cancers, including colon, breast, and lung cancer, suggesting its role in tumorigenesis and metastasis. 3. **Neurological disorders:** ITIH4 has been implicated in neurological diseases, such as multiple sclerosis, where dysregulation of ITIH4 contributes to inflammation and demyelination. In conclusion, ITIH4 plays a critical role in regulating immune function, inflammation, and tissue repair. Understanding the complex interplay of ITIH4 in these processes has significant implications for the treatment and management of various diseases, including inflammatory disorders, cancer, and neurological disorders. Further research is necessary to fully elucidate the mechanisms by which ITIH4 regulates immune responses and to explore its therapeutic potential.

Genular Protein ID: 531845149

Symbol: ITIH4_HUMAN

Name: Inter-alpha-trypsin inhibitor heavy chain H4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7805892

Title: cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein.

PubMed ID: 7805892

DOI: 10.1016/0014-5793(94)01364-7

PubMed ID: 7775381

Title: Cloning and characterization of cDNA for inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein.

PubMed ID: 7775381

DOI: 10.1093/oxfordjournals.jbchem.a124701

PubMed ID: 8797089

Title: Isolation and characterization of the human inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene (ITIHL1).

PubMed ID: 8797089

DOI: 10.1093/oxfordjournals.jbchem.a021327

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16271702

Title: BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4.

PubMed ID: 16271702

DOI: 10.1016/j.bbrc.2005.10.101

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 7541790

Title: Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma.

PubMed ID: 7541790

DOI: 10.1093/jb/117.2.400

PubMed ID: 7947966

Title: Purification and characterization of a novel substrate for plasma kallikrein (PK-120) in human plasma.

PubMed ID: 7947966

DOI: 10.1016/0167-4838(94)90122-8

PubMed ID: 10486281

Title: ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells.

PubMed ID: 10486281

DOI: 10.1006/bbrc.1999.1349

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19263524

Title: Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke.

PubMed ID: 19263524

DOI: 10.1016/j.cca.2009.01.009

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21137033

Title: The absolute quantification of eight inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4)-derived peptides in serum from breast cancer patients.

PubMed ID: 21137033

DOI: 10.1002/prca.201000035

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22171320

Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.

PubMed ID: 22171320

DOI: 10.1074/mcp.m111.013649

PubMed ID: 24884609

Title: Site-specific glycan microheterogeneity of inter-alpha-trypsin inhibitor heavy chain H4.

PubMed ID: 24884609

DOI: 10.1021/pr500394z

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12147176

Title: SNP analysis of the inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene by a fluorescence-adapted SSCP method.

PubMed ID: 12147176

DOI: 10.1186/1471-2350-3-6

Sequence Information:

  • Length: 930
  • Mass: 103357
  • Checksum: 847A9A5CB886C5A4
  • Sequence:
  • MKPPRPVRTC SKVLVLLSLL AIHQTTTAEK NGIDIYSLTV DSRVSSRFAH TVVTSRVVNR 
    ANTVQEATFQ MELPKKAFIT NFSMIIDGMT YPGIIKEKAE AQAQYSAAVA KGKSAGLVKA 
    TGRNMEQFQV SVSVAPNAKI TFELVYEELL KRRLGVYELL LKVRPQQLVK HLQMDIHIFE 
    PQGISFLETE STFMTNQLVD ALTTWQNKTK AHIRFKPTLS QQQKSPEQQE TVLDGNLIIR 
    YDVDRAISGG SIQIENGYFV HYFAPEGLTT MPKNVVFVID KSGSMSGRKI QQTREALIKI 
    LDDLSPRDQF NLIVFSTEAT QWRPSLVPAS AENVNKARSF AAGIQALGGT NINDAMLMAV 
    QLLDSSNQEE RLPEGSVSLI ILLTDGDPTV GETNPRSIQN NVREAVSGRY SLFCLGFGFD 
    VSYAFLEKLA LDNGGLARRI HEDSDSALQL QDFYQEVANP LLTAVTFEYP SNAVEEVTQN 
    NFRLLFKGSE MVVAGKLQDR GPDVLTATVS GKLPTQNITF QTESSVAEQE AEFQSPKYIF 
    HNFMERLWAY LTIQQLLEQT VSASDADQQA LRNQALNLSL AYSFVTPLTS MVVTKPDDQE 
    QSQVAEKPME GESRNRNVHS GSTFFKYYLQ GAKIPKPEAS FSPRRGWNRQ AGAAGSRMNF 
    RPGVLSSRQL GLPGPPDVPD HAAYHPFRRL AILPASAPPA TSNPDPAVSR VMNMKIEETT 
    MTTQTPAPIQ APSAILPLPG QSVERLCVDP RHRQGPVNLL SDPEQGVEVT GQYEREKAGF 
    SWIEVTFKNP LVWVHASPEH VVVTRNRRSS AYKWKETLFS VMPGLKMTMD KTGLLLLSDP 
    DKVTIGLLFW DGRGEGLRLL LRDTDRFSSH VGGTLGQFYQ EVLWGSPAAS DDGRRTLRVQ 
    GNDHSATRER RLDYQEGPPG VEISCWSVEL

Genular Protein ID: 2656310499

Symbol: B7ZKJ8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 935
  • Mass: 103881
  • Checksum: 88A1DEA331DB8BEB
  • Sequence:
  • MKPPRPVRTC SKVLVLLSLL AIHQTTTAEK NGIDIYSLTV DSRVSSRFAH TVVTSRVVNR 
    ANTVQEATFQ MELPKKAFIT NFSMIIDGMT YPGIIKEKAE AQAQYSAAVA KGKSAGLVKA 
    TGRNMEQFQV SVSVAPNAKI TFELVYEELL KRRLGVYELL LKVRPQQLVK HLQMDIHIFE 
    PQGISFLETE STFMTNQLVD ALTTWQNKTK AHIRFKPTLS QQQKSPEQQE TVLDGNLIIR 
    YDVDRAISGG SIQIENGYFV HYFAPEGLTT MPKNVVFVID KSGSMSGRKI QQTREALIKI 
    LDDLSPRDQF NLIVFSTEAT QWRPSLVPAS AENVNKARSF AAGIQALGGT NINDAMLMAV 
    QLLDSSNQEE RLPEGSVSLI ILLTDGDPTV GETNPRSIQN NVREAVSGRY SLFCLGFGFD 
    VSYAFLEKLA LDNGGLARRI HEDSDSALQL QDFYQEVANP LLTAVTFEYP SNAVEEVTQN 
    NFRLLFKGSE MVVAGKLQDR GPDVLTATVS GKLPTQNITF QTESSVAEQE AEFQSPKYIF 
    HNFMERLWAY LTIQQLLEQT VSASDADQQA LRNQALNLSL AYSFVTPLTS MVVTKPDDQE 
    QSQVAEKPME GESRNRNVHS GSTFFKYYLQ GAKIPKPGLD HTEASFSPRR GWNRQAGAAG 
    SRMNFRPGVL SSRQLGLPGP PDVPDHAAYH PFRRLAILPA SAPPATSNPD PAVSRVMNMK 
    IEETTMTTQT PAPIQAPSAI LPLPGQSVER LCVDPRHRQG PVNLLSDPEQ GVEVTGQYER 
    EKAGFSWIEV TFKNPLVWVH ASPEHVVVTR NRRSSAYKWK ETLFSVMPGL KMTMDKTGLL 
    LLSDPDKVTI GLLFWDGRGE GLRLLLRDTD RFSSHVGGTL GQFYQEVLWG SPAASDDGRR 
    TLRVQGNDHS ATRERRLDYQ EGPPGVEISC WSVEL

Genular Protein ID: 2824971921

Symbol: B2RMS9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 930
  • Mass: 103362
  • Checksum: A2EFA66EAB9DFB94
  • Sequence:
  • MKPPRPVRTC SKVLVLLSLL AIHQTTTAEK NGIDIYSLTV DSRVSSRFAH TVVTSRVVNR 
    ANTVQEATFQ MELPKKAFIT NFSMNIDGMT YPGIIKEKAE AQAQYSAAVA KGKSAGLVKA 
    TGRNMEQFQV SVSVAPNAKI TFELVYEELL KRRLGVYELL LKVRPQQLVK HLQMDIHIFE 
    PQGISFLETE STFMTNQLVD ALTTWQNKTK AHIRFKPTLS QQQKSPEQQE TVLDGNLIIR 
    YDVDRAISGG SIQIENGYFV HYFAPEGLTT MPKNVVFVID KSGSMSGRKI QQTREALIKI 
    LDDLSPRDQF NLIVFSTEAT QWRPSLVPAS AENVNKARSF AAGIQALGGT NINDAMLMAV 
    QLLDSSNQEE RLPEGSVSLI ILLTDGDPTV GETNPRSIQN NVREAVSGRY SLFCLGFGFD 
    VSYAFLEKLA LDNGGLARRI HEDSDSALQL QDFYQEVANP LLTAVTFEYP SNAVEEVTQN 
    NFRLLFKGSE MVVAGKLQDR GPDVLTATVS GKLPTQNITF QTESSVAEQE AEFQSPKYIF 
    HNFMERLWAY LTIQQLLEQT VSASDADQQA LRNQALNLSL AYSFVTPLTS MVVTKPDDQE 
    QSQVAEKPME GESRNRNVHS GSTFFKYYLQ GAKIPKPEAS FSPRRGWNRQ AGAAGSRMNF 
    RPGVLSSRQL GLPGPPDVPD HAAYHPFRRL AILPASATPA TSNPDPAVSR VMNMKIEETT 
    MTTQTPAPIQ APSAILPLPG QSVERLCVDP RHRQGPVNLL SDPEQGVEVT GQYEREKAGF 
    SWIEVTFKNP LVWVHASPEH VVVTRNRRSS AYKWKETLFS VMPGLKMTMD KTGLLLLSDP 
    DKVTIGLLFW DGRGEGLRLL LRDTDRFSSH VGGTLGQFYQ EVLWGSPAAS DDGRRTLRVQ 
    GNDHSATRER RLDYQEGPPG VEISCWSVEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.