Details for: ITIH4
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 1.74
Marker Score: 3609 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1169 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.26
Marker Score: 854 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 1.17
Marker Score: 485 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4816 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 1.04
Marker Score: 795 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71828 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48053 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 507 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30408 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 460 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5334 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.93
Marker Score: 372 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2739 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 324 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5287 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.85
Marker Score: 392 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.79
Marker Score: 7468 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1261 - Cell Name: brush cell (CL0002204)
Fold Change: 0.78
Marker Score: 708 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 395 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.75
Marker Score: 1152 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.73
Marker Score: 44648 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.72
Marker Score: 11292 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.72
Marker Score: 6169 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 176 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.62
Marker Score: 296 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.61
Marker Score: 2653 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.61
Marker Score: 3274 - Cell Name: neuron (CL0000540)
Fold Change: 0.61
Marker Score: 2466 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.58
Marker Score: 1230 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.57
Marker Score: 5932 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.57
Marker Score: 497 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.57
Marker Score: 366 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.57
Marker Score: 455 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.55
Marker Score: 20403 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.55
Marker Score: 504 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.54
Marker Score: 1776 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.54
Marker Score: 171 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.51
Marker Score: 959 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.48
Marker Score: 3084 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.47
Marker Score: 1114 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 0.43
Marker Score: 4021 - Cell Name: hepatocyte (CL0000182)
Fold Change: 0.39
Marker Score: 267 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.38
Marker Score: 1457 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 0.37
Marker Score: 5573 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.37
Marker Score: 245 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 0.37
Marker Score: 14068 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.37
Marker Score: 748 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.36
Marker Score: 149 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.35
Marker Score: 1470 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.32
Marker Score: 6275 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.32
Marker Score: 6723 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 0.3
Marker Score: 96 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 0.3
Marker Score: 2277 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.29
Marker Score: 308 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 0.29
Marker Score: 1190 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.28
Marker Score: 167 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.27
Marker Score: 72 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.27
Marker Score: 306 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.26
Marker Score: 70 - Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
Fold Change: 0.25
Marker Score: 195 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.24
Marker Score: 93 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.22
Marker Score: 62 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 0.21
Marker Score: 87 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.21
Marker Score: 755 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.21
Marker Score: 72 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: 0.21
Marker Score: 802 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.21
Marker Score: 250 - Cell Name: muscle cell (CL0000187)
Fold Change: 0.19
Marker Score: 54 - Cell Name: pro-B cell (CL0000826)
Fold Change: 0.19
Marker Score: 181 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 0.17
Marker Score: 435 - Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 0.17
Marker Score: 97 - Cell Name: renal principal cell (CL0005009)
Fold Change: 0.17
Marker Score: 132 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.17
Marker Score: 41 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.16
Marker Score: 199 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.16
Marker Score: 59 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 0.16
Marker Score: 118 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.15
Marker Score: 49 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: 0.15
Marker Score: 47 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.15
Marker Score: 79 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.15
Marker Score: 44 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.15
Marker Score: 73 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.14
Marker Score: 37 - Cell Name: interneuron (CL0000099)
Fold Change: 0.14
Marker Score: 64 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.14
Marker Score: 3548 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.14
Marker Score: 1152 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.13
Marker Score: 4308 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.13
Marker Score: 66 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 0.12
Marker Score: 31 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.12
Marker Score: 194 - Cell Name: ciliated cell (CL0000064)
Fold Change: 0.11
Marker Score: 395 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.11
Marker Score: 126 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.11
Marker Score: 50 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.11
Marker Score: 38 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.11
Marker Score: 290 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.11
Marker Score: 104 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1
Marker Score: 104 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.1
Marker Score: 189
Hover over a box to see details here...
Hover over a box to see details here...
Hover over a box to see details here...
Other Information
Genular Protein ID: 531845149
Symbol: ITIH4_HUMAN
Name: Inter-alpha-trypsin inhibitor heavy chain H4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7805892
Title: cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein.
PubMed ID: 7805892
PubMed ID: 7775381
Title: Cloning and characterization of cDNA for inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein.
PubMed ID: 7775381
PubMed ID: 8797089
Title: Isolation and characterization of the human inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene (ITIHL1).
PubMed ID: 8797089
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16271702
Title: BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4.
PubMed ID: 16271702
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 7541790
Title: Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma.
PubMed ID: 7541790
DOI: 10.1093/jb/117.2.400
PubMed ID: 7947966
Title: Purification and characterization of a novel substrate for plasma kallikrein (PK-120) in human plasma.
PubMed ID: 7947966
PubMed ID: 10486281
Title: ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells.
PubMed ID: 10486281
PubMed ID: 12754519
Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
PubMed ID: 12754519
DOI: 10.1038/nbt827
PubMed ID: 14760718
Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
PubMed ID: 14760718
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 19263524
Title: Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke.
PubMed ID: 19263524
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 21137033
Title: The absolute quantification of eight inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4)-derived peptides in serum from breast cancer patients.
PubMed ID: 21137033
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22171320
Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.
PubMed ID: 22171320
PubMed ID: 24884609
Title: Site-specific glycan microheterogeneity of inter-alpha-trypsin inhibitor heavy chain H4.
PubMed ID: 24884609
DOI: 10.1021/pr500394z
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 12147176
Title: SNP analysis of the inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene by a fluorescence-adapted SSCP method.
PubMed ID: 12147176
Sequence Information:
- Length: 930
- Mass: 103357
- Checksum: 847A9A5CB886C5A4
- Sequence:
MKPPRPVRTC SKVLVLLSLL AIHQTTTAEK NGIDIYSLTV DSRVSSRFAH TVVTSRVVNR ANTVQEATFQ MELPKKAFIT NFSMIIDGMT YPGIIKEKAE AQAQYSAAVA KGKSAGLVKA TGRNMEQFQV SVSVAPNAKI TFELVYEELL KRRLGVYELL LKVRPQQLVK HLQMDIHIFE PQGISFLETE STFMTNQLVD ALTTWQNKTK AHIRFKPTLS QQQKSPEQQE TVLDGNLIIR YDVDRAISGG SIQIENGYFV HYFAPEGLTT MPKNVVFVID KSGSMSGRKI QQTREALIKI LDDLSPRDQF NLIVFSTEAT QWRPSLVPAS AENVNKARSF AAGIQALGGT NINDAMLMAV QLLDSSNQEE RLPEGSVSLI ILLTDGDPTV GETNPRSIQN NVREAVSGRY SLFCLGFGFD VSYAFLEKLA LDNGGLARRI HEDSDSALQL QDFYQEVANP LLTAVTFEYP SNAVEEVTQN NFRLLFKGSE MVVAGKLQDR GPDVLTATVS GKLPTQNITF QTESSVAEQE AEFQSPKYIF HNFMERLWAY LTIQQLLEQT VSASDADQQA LRNQALNLSL AYSFVTPLTS MVVTKPDDQE QSQVAEKPME GESRNRNVHS GSTFFKYYLQ GAKIPKPEAS FSPRRGWNRQ AGAAGSRMNF RPGVLSSRQL GLPGPPDVPD HAAYHPFRRL AILPASAPPA TSNPDPAVSR VMNMKIEETT MTTQTPAPIQ APSAILPLPG QSVERLCVDP RHRQGPVNLL SDPEQGVEVT GQYEREKAGF SWIEVTFKNP LVWVHASPEH VVVTRNRRSS AYKWKETLFS VMPGLKMTMD KTGLLLLSDP DKVTIGLLFW DGRGEGLRLL LRDTDRFSSH VGGTLGQFYQ EVLWGSPAAS DDGRRTLRVQ GNDHSATRER RLDYQEGPPG VEISCWSVEL
Genular Protein ID: 2824971921
Symbol: B2RMS9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 930
- Mass: 103362
- Checksum: A2EFA66EAB9DFB94
- Sequence:
MKPPRPVRTC SKVLVLLSLL AIHQTTTAEK NGIDIYSLTV DSRVSSRFAH TVVTSRVVNR ANTVQEATFQ MELPKKAFIT NFSMNIDGMT YPGIIKEKAE AQAQYSAAVA KGKSAGLVKA TGRNMEQFQV SVSVAPNAKI TFELVYEELL KRRLGVYELL LKVRPQQLVK HLQMDIHIFE PQGISFLETE STFMTNQLVD ALTTWQNKTK AHIRFKPTLS QQQKSPEQQE TVLDGNLIIR YDVDRAISGG SIQIENGYFV HYFAPEGLTT MPKNVVFVID KSGSMSGRKI QQTREALIKI LDDLSPRDQF NLIVFSTEAT QWRPSLVPAS AENVNKARSF AAGIQALGGT NINDAMLMAV QLLDSSNQEE RLPEGSVSLI ILLTDGDPTV GETNPRSIQN NVREAVSGRY SLFCLGFGFD VSYAFLEKLA LDNGGLARRI HEDSDSALQL QDFYQEVANP LLTAVTFEYP SNAVEEVTQN NFRLLFKGSE MVVAGKLQDR GPDVLTATVS GKLPTQNITF QTESSVAEQE AEFQSPKYIF HNFMERLWAY LTIQQLLEQT VSASDADQQA LRNQALNLSL AYSFVTPLTS MVVTKPDDQE QSQVAEKPME GESRNRNVHS GSTFFKYYLQ GAKIPKPEAS FSPRRGWNRQ AGAAGSRMNF RPGVLSSRQL GLPGPPDVPD HAAYHPFRRL AILPASATPA TSNPDPAVSR VMNMKIEETT MTTQTPAPIQ APSAILPLPG QSVERLCVDP RHRQGPVNLL SDPEQGVEVT GQYEREKAGF SWIEVTFKNP LVWVHASPEH VVVTRNRRSS AYKWKETLFS VMPGLKMTMD KTGLLLLSDP DKVTIGLLFW DGRGEGLRLL LRDTDRFSSH VGGTLGQFYQ EVLWGSPAAS DDGRRTLRVQ GNDHSATRER RLDYQEGPPG VEISCWSVEL
Genular Protein ID: 2656310499
Symbol: B7ZKJ8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 935
- Mass: 103881
- Checksum: 88A1DEA331DB8BEB
- Sequence:
MKPPRPVRTC SKVLVLLSLL AIHQTTTAEK NGIDIYSLTV DSRVSSRFAH TVVTSRVVNR ANTVQEATFQ MELPKKAFIT NFSMIIDGMT YPGIIKEKAE AQAQYSAAVA KGKSAGLVKA TGRNMEQFQV SVSVAPNAKI TFELVYEELL KRRLGVYELL LKVRPQQLVK HLQMDIHIFE PQGISFLETE STFMTNQLVD ALTTWQNKTK AHIRFKPTLS QQQKSPEQQE TVLDGNLIIR YDVDRAISGG SIQIENGYFV HYFAPEGLTT MPKNVVFVID KSGSMSGRKI QQTREALIKI LDDLSPRDQF NLIVFSTEAT QWRPSLVPAS AENVNKARSF AAGIQALGGT NINDAMLMAV QLLDSSNQEE RLPEGSVSLI ILLTDGDPTV GETNPRSIQN NVREAVSGRY SLFCLGFGFD VSYAFLEKLA LDNGGLARRI HEDSDSALQL QDFYQEVANP LLTAVTFEYP SNAVEEVTQN NFRLLFKGSE MVVAGKLQDR GPDVLTATVS GKLPTQNITF QTESSVAEQE AEFQSPKYIF HNFMERLWAY LTIQQLLEQT VSASDADQQA LRNQALNLSL AYSFVTPLTS MVVTKPDDQE QSQVAEKPME GESRNRNVHS GSTFFKYYLQ GAKIPKPGLD HTEASFSPRR GWNRQAGAAG SRMNFRPGVL SSRQLGLPGP PDVPDHAAYH PFRRLAILPA SAPPATSNPD PAVSRVMNMK IEETTMTTQT PAPIQAPSAI LPLPGQSVER LCVDPRHRQG PVNLLSDPEQ GVEVTGQYER EKAGFSWIEV TFKNPLVWVH ASPEHVVVTR NRRSSAYKWK ETLFSVMPGL KMTMDKTGLL LLSDPDKVTI GLLFWDGRGE GLRLLLRDTD RFSSHVGGTL GQFYQEVLWG SPAASDDGRR TLRVQGNDHS ATRERRLDYQ EGPPGVEISC WSVEL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.