Details for: JARID2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.88
Marker Score: 61,393 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.86
Marker Score: 906 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.5
Marker Score: 10,470 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.38
Marker Score: 80,525 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.35
Marker Score: 2,661 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 2.33
Marker Score: 1,911 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.3
Marker Score: 5,051 - Cell Name: stellate neuron (CL0000122)
Fold Change: 2.22
Marker Score: 11,912 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.21
Marker Score: 43,931 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.19
Marker Score: 9,085 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.19
Marker Score: 80,729 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.17
Marker Score: 5,428 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.13
Marker Score: 11,199 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.12
Marker Score: 2,341 - Cell Name: renal principal cell (CL0005009)
Fold Change: 2.1
Marker Score: 1,621 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.1
Marker Score: 614 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 2.06
Marker Score: 1,358 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.99
Marker Score: 75,385 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.98
Marker Score: 3,809 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.94
Marker Score: 1,023 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.92
Marker Score: 1,657 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.91
Marker Score: 2,202 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.91
Marker Score: 6,403 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.89
Marker Score: 116,522 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.88
Marker Score: 786 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.87
Marker Score: 33,256 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 1.82
Marker Score: 17,100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.81
Marker Score: 1,060 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.81
Marker Score: 18,710 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.76
Marker Score: 1,021 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.76
Marker Score: 1,521 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.75
Marker Score: 16,637 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.75
Marker Score: 548 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.73
Marker Score: 2,901 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 1.73
Marker Score: 38,556 - Cell Name: mesangial cell (CL0000650)
Fold Change: 1.71
Marker Score: 2,061 - Cell Name: neuron (CL0000540)
Fold Change: 1.7
Marker Score: 6,923 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 1.69
Marker Score: 7,809 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.69
Marker Score: 4,814 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 1.68
Marker Score: 12,865 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.67
Marker Score: 14,387 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 1.67
Marker Score: 539 - Cell Name: podocyte (CL0000653)
Fold Change: 1.66
Marker Score: 613 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.65
Marker Score: 5,866 - Cell Name: endocrine cell (CL0000163)
Fold Change: 1.64
Marker Score: 848 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.64
Marker Score: 6,331 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.63
Marker Score: 949 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.63
Marker Score: 3,893 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.62
Marker Score: 1,956 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.6
Marker Score: 898 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.6
Marker Score: 3,765 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.6
Marker Score: 54,268 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.59
Marker Score: 1,665 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.58
Marker Score: 943 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.55
Marker Score: 6,481 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.54
Marker Score: 1,903 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.52
Marker Score: 2,047 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.52
Marker Score: 2,344 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.52
Marker Score: 583 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.51
Marker Score: 1,627 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.5
Marker Score: 744 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.49
Marker Score: 408 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.41
Marker Score: 679 - Cell Name: male germ cell (CL0000015)
Fold Change: 1.4
Marker Score: 403 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 1.35
Marker Score: 1,688 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.35
Marker Score: 813 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.35
Marker Score: 75,636 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 1.35
Marker Score: 852 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.34
Marker Score: 20,976 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.34
Marker Score: 744 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 1.34
Marker Score: 1,882 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 1.34
Marker Score: 455 - Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 1.33
Marker Score: 478 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.32
Marker Score: 992 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.3
Marker Score: 13,153 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.28
Marker Score: 1,816 - Cell Name: proerythroblast (CL0000547)
Fold Change: 1.28
Marker Score: 865 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.26
Marker Score: 624 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.26
Marker Score: 610 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 1.24
Marker Score: 418 - Cell Name: CD38-negative naive B cell (CL0002102)
Fold Change: 1.23
Marker Score: 2,577 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 1.22
Marker Score: 833 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.21
Marker Score: 1,278 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.21
Marker Score: 1,195 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.21
Marker Score: 1,717 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.21
Marker Score: 1,150 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 1.2
Marker Score: 1,452 - Cell Name: fat cell (CL0000136)
Fold Change: 1.2
Marker Score: 672 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.2
Marker Score: 486 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.2
Marker Score: 1,269 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.19
Marker Score: 344 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 1.19
Marker Score: 17,802 - Cell Name: macroglial cell (CL0000126)
Fold Change: 1.19
Marker Score: 2,734 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.19
Marker Score: 676 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.18
Marker Score: 19,001 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.18
Marker Score: 1,322 - Cell Name: erythroblast (CL0000765)
Fold Change: 1.18
Marker Score: 734 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.16
Marker Score: 1,244 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 1.16
Marker Score: 4,830 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 1.16
Marker Score: 2,844
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3091748211
Symbol: JARD2_HUMAN
Name: Protein Jumonji
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8894700
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20075857
Title: JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.
PubMed ID: 20075857
DOI: 10.1038/nature08788
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 35887345
Title: DNA Methylation Signature for JARID2-Neurodevelopmental Syndrome.
PubMed ID: 35887345
DOI: 10.3390/ijms23148001
PubMed ID: 29499137
Title: Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
PubMed ID: 29499137
PubMed ID: 31959557
Title: A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.
PubMed ID: 31959557
Sequence Information:
- Length: 1246
- Mass: 138734
- Checksum: E4929984259110DB
- Sequence:
MSKERPKRNI IQKKYDDSDG IPWSEERVVR KVLYLSLKEF KNSQKRQHAE GIAGSLKTVN GLLGNDQSKG LGPASEQSEN EKDDASQVSS TSNDVSSSDF EEGPSRKRPR LQAQRKFAQS QPNSPSTTPV KIVEPLLPPP ATQISDLSKR KPKTEDFLTF LCLRGSPALP NSMVYFGSSQ DEEEVEEEDD ETEDVKTATN NASSSCQSTP RKGKTHKHVH NGHVFNGSSR STREKEPVQK HKSKEATPAK EKHSDHRADS RREQASANHP AAAPSTGSSA KGLAATHHHP PLHRSAQDLR KQVSKVNGVT RMSSLGAGVT SAKKMREVRP SPSKTVKYTA TVTKGAVTYT KAKRELVKDT KPNHHKPSSA VNHTISGKTE SSNAKTRKQV LSLGGASKST GPAVNGLKVS GRLNPKSCTK EVGGRQLREG LQLREGLRNS KRRLEEAHQA EKPQSPPKKM KGAAGPAEGP GKKAPAERGL LNGHVKKEVP ERSLERNRPK RATAGKSTPG RQAHGKADSA SCENRSTSQP ESVHKPQDSG KAEKGGGKAG WAAMDEIPVL RPSAKEFHDP LIYIESVRAQ VEKFGMCRVI PPPDWRPECK LNDEMRFVTQ IQHIHKLGRR WGPNVQRLAC IKKHLKSQGI TMDELPLIGG CELDLACFFR LINEMGGMQQ VTDLKKWNKL ADMLRIPRTA QDRLAKLQEA YCQYLLSYDS LSPEEHRRLE KEVLMEKEIL EKRKGPLEGH TENDHHKFHP LPRFEPKNGL IHGVAPRNGF RSKLKEVGQA QLKTGRRRLF AQEKEVVKEE EEDKGVLNDF HKCIYKGRSV SLTTFYRTAR NIMSMCFSKE PAPAEIEQEY WRLVEEKDCH VAVHCGKVDT NTHGSGFPVG KSEPFSRHGW NLTVLPNNTG SILRHLGAVP GVTIPWLNIG MVFSTSCWSR DQNHLPYIDY LHTGADCIWY CIPAEEENKL EDVVHTLLQA NGTPGLQMLE SNVMISPEVL CKEGIKVHRT VQQSGQFVVC FPGSFVSKVC CGYSVSETVH FATTQWTSMG FETAKEMKRR HIAKPFSMEK LLYQIAQAEA KKENGPTLST ISALLDELRD TELRQRRQLF EAGLHSSARY GSHDGSSTVA DGKKKPRKWL QLETSERRCQ ICQHLCYLSM VVQENENVVF CLECALRHVE KQKSCRGLKL MYRYDEEQII SLVNQICGKV SGKNGSIENC LSKPTPKRGP RKRATVDVPP SRLSASSSSK SASSSS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.