Details for: KIF5A

Gene ID: 3798

Symbol: KIF5A

Ensembl ID: ENSG00000155980

Description: kinesin family member 5A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 165.3538
    Cell Significance Index: -25.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 102.9398
    Cell Significance Index: -26.1100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.1119
    Cell Significance Index: -26.0300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.4430
    Cell Significance Index: 58.5900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.4051
    Cell Significance Index: 37.2100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.6880
    Cell Significance Index: 103.7500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.4811
    Cell Significance Index: 32.4300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.3869
    Cell Significance Index: 278.2200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.3624
    Cell Significance Index: 38.8800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2853
    Cell Significance Index: 461.0100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.2176
    Cell Significance Index: 10.0500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.7096
    Cell Significance Index: 12.1600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.5606
    Cell Significance Index: 5.8400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5339
    Cell Significance Index: 369.2900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4910
    Cell Significance Index: 6.5500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4708
    Cell Significance Index: 31.6600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.3931
    Cell Significance Index: 3.0300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3701
    Cell Significance Index: 16.3700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.3652
    Cell Significance Index: 4.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3416
    Cell Significance Index: 12.9400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.1935
    Cell Significance Index: 2.5100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1747
    Cell Significance Index: 9.1700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.1676
    Cell Significance Index: 2.0900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0283
    Cell Significance Index: 38.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0043
    Cell Significance Index: -6.5700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0044
    Cell Significance Index: -8.1500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0062
    Cell Significance Index: -11.7500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0195
    Cell Significance Index: -12.4100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0271
    Cell Significance Index: -19.8400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0276
    Cell Significance Index: -20.4100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0368
    Cell Significance Index: -0.7800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0372
    Cell Significance Index: -16.4400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0390
    Cell Significance Index: -21.9900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0436
    Cell Significance Index: -27.2300
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0440
    Cell Significance Index: -0.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0467
    Cell Significance Index: -21.1900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0491
    Cell Significance Index: -26.7900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0572
    Cell Significance Index: -7.8500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0610
    Cell Significance Index: -8.8700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0698
    Cell Significance Index: -20.0800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0715
    Cell Significance Index: -12.8900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0881
    Cell Significance Index: -3.8300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0916
    Cell Significance Index: -11.7400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1157
    Cell Significance Index: -22.9700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.1311
    Cell Significance Index: -1.5300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1325
    Cell Significance Index: -27.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1337
    Cell Significance Index: -7.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1539
    Cell Significance Index: -4.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1556
    Cell Significance Index: -19.1300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1600
    Cell Significance Index: -27.3200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1644
    Cell Significance Index: -3.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1760
    Cell Significance Index: -11.1000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1778
    Cell Significance Index: -22.9700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1999
    Cell Significance Index: -20.4200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2010
    Cell Significance Index: -6.5800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2069
    Cell Significance Index: -24.4000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2210
    Cell Significance Index: -7.0400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2246
    Cell Significance Index: -26.1700
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2258
    Cell Significance Index: -2.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2493
    Cell Significance Index: -28.5600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2533
    Cell Significance Index: -26.3700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2627
    Cell Significance Index: -5.6200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.2717
    Cell Significance Index: -2.9600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2804
    Cell Significance Index: -5.6300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3065
    Cell Significance Index: -22.8400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3136
    Cell Significance Index: -7.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3806
    Cell Significance Index: -29.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3849
    Cell Significance Index: -24.8300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4066
    Cell Significance Index: -21.1800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.4114
    Cell Significance Index: -5.9000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4145
    Cell Significance Index: -10.3400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4179
    Cell Significance Index: -14.6400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4286
    Cell Significance Index: -9.2600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.4383
    Cell Significance Index: -4.1700
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.4627
    Cell Significance Index: -3.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4692
    Cell Significance Index: -22.0500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5063
    Cell Significance Index: -7.2500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.5187
    Cell Significance Index: -23.5100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.5519
    Cell Significance Index: -6.6900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5532
    Cell Significance Index: -11.5500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.5701
    Cell Significance Index: -26.5800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5871
    Cell Significance Index: -20.4000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5946
    Cell Significance Index: -30.8900
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.6395
    Cell Significance Index: -8.0700
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.6594
    Cell Significance Index: -8.7900
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -0.6613
    Cell Significance Index: -5.3400
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.6740
    Cell Significance Index: -8.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7024
    Cell Significance Index: -20.6900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.7131
    Cell Significance Index: -11.4400
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.7291
    Cell Significance Index: -14.3500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.7468
    Cell Significance Index: -5.0600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7475
    Cell Significance Index: -27.4400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.7832
    Cell Significance Index: -24.7700
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.7867
    Cell Significance Index: -8.6800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.8013
    Cell Significance Index: -22.9700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8224
    Cell Significance Index: -21.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.8264
    Cell Significance Index: -29.0400
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.8385
    Cell Significance Index: -7.5800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.8570
    Cell Significance Index: -25.1700
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.8600
    Cell Significance Index: -17.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Microtubule-based motor activity:** KIF5A is a microtubule-associated motor protein that utilizes the energy from ATP hydrolysis to move along microtubules, facilitating the transport of cargo. 2. **Axonal and dendritic transport:** KIF5A is involved in the transport of vesicles, proteins, and other cargo along axons and dendrites, essential for neuronal function and development. 3. **Immune system involvement:** KIF5A is expressed in immune cells, such as dendritic cells, and is involved in the transport of MHC class II antigens, facilitating immune response. 4. **Cytoskeletal binding:** KIF5A interacts with various cytoskeletal proteins, including tubulin and dynein, to regulate its activity and cargo transport. **Pathways and Functions:** 1. **Adaptive immune system:** KIF5A is involved in the transport of MHC class II antigens, which are essential for the activation of T-cells and the initiation of the adaptive immune response. 2. **Anterograde axonal protein transport:** KIF5A facilitates the transport of proteins and vesicles from the cell body to the axon terminals, essential for neuronal function and development. 3. **Dendritic transport of neurotransmitter receptor complex:** KIF5A is involved in the transport of neurotransmitter receptors from the cell body to the dendrites, regulating synaptic transmission and neuronal plasticity. 4. **Ciliary rootlet and ciliary transport:** KIF5A interacts with ciliary proteins to regulate ciliary movement and transport of cargo. **Clinical Significance:** 1. **Neurological disorders:** Mutations in the KIF5A gene have been associated with various neurological disorders, including Charcot-Marie-Tooth disease, which is characterized by peripheral neuropathy and muscle atrophy. 2. **Immune system dysregulation:** Abnormal expression or function of KIF5A has been linked to immune system dysregulation, including autoimmune diseases such as multiple sclerosis. 3. **Cancer:** KIF5A has been implicated in the transport of proteins and vesicles involved in cancer cell migration and invasion. 4. **Neurodegenerative diseases:** KIF5A may play a role in the transport of proteins involved in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. In conclusion, the KIF5A gene is a critical component of the cytoskeleton that plays a vital role in various cellular processes, including axonal and dendritic transport, immune response, and neurological function. Understanding the functions and dysregulation of KIF5A is essential for the development of novel therapeutic strategies for neurological and immune-related disorders.

Genular Protein ID: 3659344230

Symbol: KIF5A_HUMAN

Name: Kinesin heavy chain isoform 5A

UniProtKB Accession Codes:

Q12840 A6H8M5 Q4LE26

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7514426

Title: Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.

PubMed ID: 7514426

DOI: 10.1016/0896-6273(94)90314-x

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20386726

Title: Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.

PubMed ID: 20386726

DOI: 10.1371/journal.pbio.1000350

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25898167

Title: BORC, a multisubunit complex that regulates lysosome positioning.

PubMed ID: 25898167

DOI: 10.1016/j.devcel.2015.02.011

PubMed ID: 12355402

Title: A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10).

PubMed ID: 12355402

DOI: 10.1086/344210

PubMed ID: 15452312

Title: Evidence of kinesin heavy chain (KIF5A) involvement in pure hereditary spastic paraplegia.

PubMed ID: 15452312

DOI: 10.1212/01.wnl.0000138731.60693.d2

PubMed ID: 16476820

Title: A missense mutation in the coiled-coil domain of the KIF5A gene and late-onset hereditary spastic paraplegia.

PubMed ID: 16476820

DOI: 10.1001/archneur.63.2.284

PubMed ID: 16489470

Title: Mutation in KIF5A can also cause adult-onset hereditary spastic paraplegia.

PubMed ID: 16489470

DOI: 10.1007/s10048-005-0027-8

PubMed ID: 18203753

Title: Effect of spastic paraplegia mutations in KIF5A kinesin on transport activity.

PubMed ID: 18203753

DOI: 10.1093/hmg/ddn014

PubMed ID: 18245137

Title: SPG10 is a rare cause of spastic paraplegia in European families.

PubMed ID: 18245137

DOI: 10.1136/jnnp.2007.137596

PubMed ID: 18853458

Title: Complicated forms of autosomal dominant hereditary spastic paraplegia are frequent in SPG10.

PubMed ID: 18853458

DOI: 10.1002/humu.20920

PubMed ID: 21107874

Title: A novel mutation in KIF5A gene causing hereditary spastic paraplegia with axonal neuropathy.

PubMed ID: 21107874

DOI: 10.1007/s10072-010-0445-8

PubMed ID: 24215330

Title: Targeted exome sequencing for mitochondrial disorders reveals high genetic heterogeneity.

PubMed ID: 24215330

DOI: 10.1186/1471-2350-14-118

PubMed ID: 27463701

Title: KIF5A mutations cause an infantile onset phenotype including severe myoclonus with evidence of mitochondrial dysfunction.

PubMed ID: 27463701

DOI: 10.1002/ana.24744

PubMed ID: 27414745

Title: KIF5A de novo mutation associated with myoclonic seizures and neonatal onset progressive leukoencephalopathy.

PubMed ID: 27414745

DOI: 10.1111/cge.12831

PubMed ID: 29342275

Title: Hot-spot KIF5A mutations cause familial ALS.

PubMed ID: 29342275

DOI: 10.1093/brain/awx370

PubMed ID: 29566793

Title: Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

PubMed ID: 29566793

DOI: 10.1016/j.neuron.2018.02.027

Sequence Information:

  • Length: 1032
  • Mass: 117378
  • Checksum: C4C6C12342040796
  • Sequence:
    • MAETNNECSI KVLCRFRPLN QAEILRGDKF IPIFQGDDSV VIGGKPYVFD RVFPPNTTQE 
QVYHACAMQI VKDVLAGYNG TIFAYGQTSS GKTHTMEGKL HDPQLMGIIP RIARDIFNHI 
YSMDENLEFH IKVSYFEIYL DKIRDLLDVT KTNLSVHEDK NRVPFVKGCT ERFVSSPEEI 
LDVIDEGKSN RHVAVTNMNE HSSRSHSIFL INIKQENMET EQKLSGKLYL VDLAGSEKVS 
KTGAEGAVLD EAKNINKSLS ALGNVISALA EGTKSYVPYR DSKMTRILQD SLGGNCRTTM 
FICCSPSSYN DAETKSTLMF GQRAKTIKNT ASVNLELTAE QWKKKYEKEK EKTKAQKETI 
AKLEAELSRW RNGENVPETE RLAGEEAALG AELCEETPVN DNSSIVVRIA PEERQKYEEE 
IRRLYKQLDD KDDEINQQSQ LIEKLKQQML DQEELLVSTR GDNEKVQREL SHLQSENDAA 
KDEVKEVLQA LEELAVNYDQ KSQEVEEKSQ QNQLLVDELS QKVATMLSLE SELQRLQEVS 
GHQRKRIAEV LNGLMKDLSE FSVIVGNGEI KLPVEISGAI EEEFTVARLY ISKIKSEVKS 
VVKRCRQLEN LQVECHRKME VTGRELSSCQ LLISQHEAKI RSLTEYMQSV ELKKRHLEES 
YDSLSDELAK LQAQETVHEV ALKDKEPDTQ DADEVKKALE LQMESHREAH HRQLARLRDE 
INEKQKTIDE LKDLNQKLQL ELEKLQADYE KLKSEEHEKS TKLQELTFLY ERHEQSKQDL 
KGLEETVARE LQTLHNLRKL FVQDVTTRVK KSAEMEPEDS GGIHSQKQKI SFLENNLEQL 
TKVHKQLVRD NADLRCELPK LEKRLRATAE RVKALEGALK EAKEGAMKDK RRYQQEVDRI 
KEAVRYKSSG KRGHSAQIAK PVRPGHYPAS SPTNPYGTRS PECISYTNSL FQNYQNLYLQ 
ATPSSTSDMY FANSCTSSGA TSSGGPLASY QKANMDNGNA TDINDNRSDL PCGYEAEDQA 
KLFPLHQETA AS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.