Details for: KIF5B
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 596.3539
Cell Significance Index: -92.7600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 353.5279
Cell Significance Index: -89.6700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 255.8821
Cell Significance Index: -105.4100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 215.9608
Cell Significance Index: -101.9600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 203.3687
Cell Significance Index: -82.6200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 186.8638
Cell Significance Index: -96.1200 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 152.2603
Cell Significance Index: -102.1700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 87.4581
Cell Significance Index: -83.5000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 80.6314
Cell Significance Index: -99.4200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 30.6324
Cell Significance Index: -82.0600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 25.6586
Cell Significance Index: -101.2500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 22.6766
Cell Significance Index: -69.6500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 18.0367
Cell Significance Index: -39.4800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 3.4557
Cell Significance Index: 180.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.2337
Cell Significance Index: 402.6700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 2.2219
Cell Significance Index: 77.2100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.2202
Cell Significance Index: 272.9900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.0785
Cell Significance Index: 55.5000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.9560
Cell Significance Index: 91.2000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.8590
Cell Significance Index: 87.3700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.7333
Cell Significance Index: 1565.0800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.6095
Cell Significance Index: 43.8100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.5537
Cell Significance Index: 848.4900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.5403
Cell Significance Index: 211.5300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.5142
Cell Significance Index: 300.5100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.2652
Cell Significance Index: 253.8000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.2569
Cell Significance Index: 75.4600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.2010
Cell Significance Index: 77.4900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.1817
Cell Significance Index: 116.9000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.1372
Cell Significance Index: 502.7800 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.1195
Cell Significance Index: 144.6300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.0361
Cell Significance Index: 77.2200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.9151
Cell Significance Index: 117.3100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.8728
Cell Significance Index: 18.2700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.8454
Cell Significance Index: 22.2300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.8400
Cell Significance Index: 7.7400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8259
Cell Significance Index: 23.8000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.8053
Cell Significance Index: 288.8600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.7321
Cell Significance Index: 41.0800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.6741
Cell Significance Index: 35.0200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.5885
Cell Significance Index: 41.6200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.5301
Cell Significance Index: 62.5200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5202
Cell Significance Index: 39.9200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3236
Cell Significance Index: 223.8000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2641
Cell Significance Index: 45.1000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2588
Cell Significance Index: 13.5900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2439
Cell Significance Index: 46.4200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2274
Cell Significance Index: 13.9800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1453
Cell Significance Index: 15.8000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.0960
Cell Significance Index: 0.5800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0846
Cell Significance Index: 159.3800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0394
Cell Significance Index: 28.9100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0310
Cell Significance Index: 47.8000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0305
Cell Significance Index: 19.3500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0179
Cell Significance Index: 32.9200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0021
Cell Significance Index: -2.8800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0071
Cell Significance Index: -0.0900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0095
Cell Significance Index: -4.2900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0150
Cell Significance Index: -11.3300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0171
Cell Significance Index: -12.6900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0318
Cell Significance Index: -2.0100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0603
Cell Significance Index: -1.0100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0808
Cell Significance Index: -50.4300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0906
Cell Significance Index: -10.3400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0942
Cell Significance Index: -4.2700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0972
Cell Significance Index: -9.9300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1101
Cell Significance Index: -62.1100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1891
Cell Significance Index: -5.4200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2090
Cell Significance Index: -44.0200 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2783
Cell Significance Index: -6.4300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3013
Cell Significance Index: -86.7000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.3443
Cell Significance Index: -50.0500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.3933
Cell Significance Index: -11.5500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.4415
Cell Significance Index: -3.6000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.4535
Cell Significance Index: -52.8500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.4680
Cell Significance Index: -13.0800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4828
Cell Significance Index: -55.3100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.5585
Cell Significance Index: -7.6200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.6374
Cell Significance Index: -42.8600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.6549
Cell Significance Index: -7.1200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.6598
Cell Significance Index: -17.6800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.7328
Cell Significance Index: -13.5500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7350
Cell Significance Index: -23.5400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.8222
Cell Significance Index: -85.6100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.9723
Cell Significance Index: -77.0100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.0287
Cell Significance Index: -25.7200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -1.2256
Cell Significance Index: -23.9200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.2610
Cell Significance Index: -27.3200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.3142
Cell Significance Index: -33.7800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.3462
Cell Significance Index: -36.0100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.3572
Cell Significance Index: -60.0300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -1.4077
Cell Significance Index: -24.8800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -1.4090
Cell Significance Index: -36.0000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.6321
Cell Significance Index: -100.0600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -1.6715
Cell Significance Index: -63.3000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -1.6804
Cell Significance Index: -19.0900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -1.7080
Cell Significance Index: -29.2700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.8517
Cell Significance Index: -93.5800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -1.9139
Cell Significance Index: -45.9000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -1.9894
Cell Significance Index: -29.3700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2214444549
Symbol: KINH_HUMAN
Name: Conventional kinesin heavy chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1607388
Title: Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells.
PubMed ID: 1607388
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15459722
Title: Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons.
PubMed ID: 15459722
DOI: 10.1038/ncb1169
PubMed ID: 15905402
Title: The intracellular fate of Salmonella depends on the recruitment of kinesin.
PubMed ID: 15905402
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17532644
Title: Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport.
PubMed ID: 17532644
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 20682791
Title: A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.
PubMed ID: 20682791
PubMed ID: 20386726
Title: Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.
PubMed ID: 20386726
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22172677
Title: Arl8 and SKIP act together to link lysosomes to kinesin-1.
PubMed ID: 22172677
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 23011729
Title: Quantitative measurements and modeling of cargo-motor interactions during fast transport in the living axon.
PubMed ID: 23011729
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 24088571
Title: Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity.
PubMed ID: 24088571
PubMed ID: 24995978
Title: Glucose regulates mitochondrial motility via Milton modification by O-GlcNAc transferase.
PubMed ID: 24995978
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 8606779
Title: Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.
PubMed ID: 8606779
DOI: 10.1038/380550a0
PubMed ID: 12368902
Title: Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
PubMed ID: 12368902
DOI: 10.1038/nsb852
PubMed ID: 17470637
Title: The beginning of kinesin's force-generating cycle visualized at 9-A resolution.
PubMed ID: 17470637
Sequence Information:
- Length: 963
- Mass: 109685
- Checksum: A1FE5760C3250C8B
- Sequence:
MADLAECNIK VMCRFRPLNE SEVNRGDKYI AKFQGEDTVV IASKPYAFDR VFQSSTSQEQ VYNDCAKKIV KDVLEGYNGT IFAYGQTSSG KTHTMEGKLH DPEGMGIIPR IVQDIFNYIY SMDENLEFHI KVSYFEIYLD KIRDLLDVSK TNLSVHEDKN RVPYVKGCTE RFVCSPDEVM DTIDEGKSNR HVAVTNMNEH SSRSHSIFLI NVKQENTQTE QKLSGKLYLV DLAGSEKVSK TGAEGAVLDE AKNINKSLSA LGNVISALAE GSTYVPYRDS KMTRILQDSL GGNCRTTIVI CCSPSSYNES ETKSTLLFGQ RAKTIKNTVC VNVELTAEQW KKKYEKEKEK NKILRNTIQW LENELNRWRN GETVPIDEQF DKEKANLEAF TVDKDITLTN DKPATAIGVI GNFTDAERRK CEEEIAKLYK QLDDKDEEIN QQSQLVEKLK TQMLDQEELL ASTRRDQDNM QAELNRLQAE NDASKEEVKE VLQALEELAV NYDQKSQEVE DKTKEYELLS DELNQKSATL ASIDAELQKL KEMTNHQKKR AAEMMASLLK DLAEIGIAVG NNDVKQPEGT GMIDEEFTVA RLYISKMKSE VKTMVKRCKQ LESTQTESNK KMEENEKELA ACQLRISQHE AKIKSLTEYL QNVEQKKRQL EESVDALSEE LVQLRAQEKV HEMEKEHLNK VQTANEVKQA VEQQIQSHRE THQKQISSLR DEVEAKAKLI TDLQDQNQKM MLEQERLRVE HEKLKATDQE KSRKLHELTV MQDRREQARQ DLKGLEETVA KELQTLHNLR KLFVQDLATR VKKSAEIDSD DTGGSAAQKQ KISFLENNLE QLTKVHKQLV RDNADLRCEL PKLEKRLRAT AERVKALESA LKEAKENASR DRKRYQQEVD RIKEAVRSKN MARRGHSAQI AKPIRPGQHP AASPTHPSAI RGGGAFVQNS QPVAVRGGGG KQV
Genular Protein ID: 1158913178
Symbol: Q6P164_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 345
- Mass: 38716
- Checksum: 133721DA5C8697BE
- Sequence:
MADLAECNIK VMCRFRPLNE SEVNRGDKYI AKFQGEDTVV IASKPYAFDR VFQSSTSQEQ VYNDCAKKIV KDVLEGYNGT IFAYGQTSSG KTHTMEGKLH DPEGMGIIPR IVQDIFNYIY SMDENLEFHI KVSYFEIYLD KIRDLLDVSK TNLSVHEDKN RVPYVKGCTE RFVCSPDEVM DTIDEGKSNR HVAVTNMNEH SSRSHSIFLI NVKQENTQTE QKLSGKLYLV DLAGSEKVSK TGAEGAVLDE AKNINKSLSA LGNVISALAE GSTYVPYRDS KMTRILQDSL GGNCRTTIVI CCSPSSYNES ETKSTLLFGQ RAKTIKNTVC VNVELTAEQW KKKKK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.