Details for: KIF11

Gene ID: 3832

Symbol: KIF11

Ensembl ID: ENSG00000138160

Description: kinesin family member 11

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 34.0241
    Cell Significance Index: -8.6300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 19.5320
    Cell Significance Index: -7.9400
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 11.3984
    Cell Significance Index: 187.8300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 8.3478
    Cell Significance Index: -7.9700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.8940
    Cell Significance Index: -8.5000
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 5.0146
    Cell Significance Index: -0.7800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.5724
    Cell Significance Index: -9.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0435
    Cell Significance Index: 198.5900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9990
    Cell Significance Index: 98.8300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8725
    Cell Significance Index: 94.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.8684
    Cell Significance Index: 48.7300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.7014
    Cell Significance Index: -1.5400
  • Cell Name: salivary gland cell (CL0009005)
    Fold Change: 0.6628
    Cell Significance Index: 8.2300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5663
    Cell Significance Index: 66.7800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5520
    Cell Significance Index: 109.5400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5260
    Cell Significance Index: 14.7000
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: 0.5005
    Cell Significance Index: 2.8500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.4942
    Cell Significance Index: 13.2200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4888
    Cell Significance Index: 441.3900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.4673
    Cell Significance Index: 5.0800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4280
    Cell Significance Index: 49.8800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3464
    Cell Significance Index: 23.9600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.2955
    Cell Significance Index: 8.7000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2814
    Cell Significance Index: 7.5400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2400
    Cell Significance Index: 14.4100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2263
    Cell Significance Index: 6.5200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2109
    Cell Significance Index: 3.0200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2070
    Cell Significance Index: 33.6700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1945
    Cell Significance Index: 6.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1584
    Cell Significance Index: 86.5200
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.1450
    Cell Significance Index: 1.1000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1395
    Cell Significance Index: 2.9200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1326
    Cell Significance Index: 6.8900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1148
    Cell Significance Index: 2.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0987
    Cell Significance Index: 19.7900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0965
    Cell Significance Index: 2.0900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0653
    Cell Significance Index: 45.1800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0574
    Cell Significance Index: 2.6000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0492
    Cell Significance Index: 21.7600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0453
    Cell Significance Index: 1.4500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0393
    Cell Significance Index: 1.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0388
    Cell Significance Index: 13.9300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0371
    Cell Significance Index: 0.7900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0172
    Cell Significance Index: 2.1100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0112
    Cell Significance Index: 0.3000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0047
    Cell Significance Index: 0.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0005
    Cell Significance Index: 0.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0002
    Cell Significance Index: -0.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0002
    Cell Significance Index: -0.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0006
    Cell Significance Index: -1.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0043
    Cell Significance Index: -5.7900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0103
    Cell Significance Index: -6.5400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0104
    Cell Significance Index: -7.6100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0110
    Cell Significance Index: -0.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0121
    Cell Significance Index: -9.1600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0137
    Cell Significance Index: -10.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0143
    Cell Significance Index: -0.2400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0143
    Cell Significance Index: -6.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0157
    Cell Significance Index: -9.8300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0160
    Cell Significance Index: -4.6000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0167
    Cell Significance Index: -2.3000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0173
    Cell Significance Index: -9.7700
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0191
    Cell Significance Index: -0.1200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0368
    Cell Significance Index: -0.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0387
    Cell Significance Index: -5.6200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0405
    Cell Significance Index: -5.1900
  • Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
    Fold Change: -0.0418
    Cell Significance Index: -0.3800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0443
    Cell Significance Index: -4.5300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0462
    Cell Significance Index: -2.8300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0463
    Cell Significance Index: -7.9100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0495
    Cell Significance Index: -10.4300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0496
    Cell Significance Index: -3.1300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0549
    Cell Significance Index: -0.9400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0564
    Cell Significance Index: -0.7700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0584
    Cell Significance Index: -4.1300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0648
    Cell Significance Index: -4.1800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0707
    Cell Significance Index: -9.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0742
    Cell Significance Index: -8.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0758
    Cell Significance Index: -4.6600
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.0803
    Cell Significance Index: -0.6900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0817
    Cell Significance Index: -8.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0907
    Cell Significance Index: -4.0100
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.0935
    Cell Significance Index: -0.6800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0989
    Cell Significance Index: -7.5900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1046
    Cell Significance Index: -1.7600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1050
    Cell Significance Index: -5.4700
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.1065
    Cell Significance Index: -0.2400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1092
    Cell Significance Index: -8.6500
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.1180
    Cell Significance Index: -0.7000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1186
    Cell Significance Index: -2.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1209
    Cell Significance Index: -4.5800
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: -0.1211
    Cell Significance Index: -1.0000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1240
    Cell Significance Index: -8.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1256
    Cell Significance Index: -9.3600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1274
    Cell Significance Index: -1.9200
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.1298
    Cell Significance Index: -1.8200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1340
    Cell Significance Index: -6.3000
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.1358
    Cell Significance Index: -1.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1473
    Cell Significance Index: -6.8700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1657
    Cell Significance Index: -1.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Kinesin-like protein:** KIF11 belongs to the kinesin superfamily, a group of motor proteins that utilize microtubule-based movement to transport cargo along microtubules. 2. **Microtubule motor activity:** KIF11 exhibits plus-end-directed microtubule motor activity, which enables it to move cargo along microtubules towards the plus end. 3. **Cell division:** KIF11 is involved in the regulation of mitotic cell cycle, mitotic centrosome separation, and spindle organization, highlighting its role in cell division and chromosomal segregation. 4. **Immune system regulation:** KIF11 is significantly expressed in immune cells, such as innate lymphoid cells and antigen-presenting cells, suggesting its involvement in immune system regulation and immune cell development. 5. **Golgi-to-ER retrograde transport:** KIF11 is also involved in the regulation of Golgi-to-ER retrograde traffic, highlighting its role in protein trafficking and secretion. **Pathways and Functions:** 1. **Adaptive immune system:** KIF11 is involved in the regulation of immune cell development, differentiation, and function, particularly in the context of innate lymphoid cells and antigen-presenting cells. 2. **Cell division:** KIF11 regulates the mitotic cell cycle, mitotic centrosome separation, and spindle organization, ensuring accurate chromosomal segregation and proper cell division. 3. **Microtubule dynamics:** KIF11 exhibits plus-end-directed microtubule motor activity, enabling it to move cargo along microtubules towards the plus end, which is crucial for various cellular processes, including protein trafficking and secretion. 4. **Golgi-to-ER retrograde transport:** KIF11 regulates the transport of proteins and lipids from the Golgi apparatus to the endoplasmic reticulum, which is essential for protein folding, modification, and secretion. 5. **Spindle organization:** KIF11 is involved in the organization of the mitotic spindle, ensuring proper chromosome alignment and segregation during cell division. **Clinical Significance:** 1. **Immunodeficiency disorders:** Dysregulation of KIF11 has been implicated in immunodeficiency disorders, such as severe combined immunodeficiency (SCID), highlighting its importance in immune system development and function. 2. **Cancer:** Alterations in KIF11 expression have been observed in various types of cancer, including leukemia and lymphoma, suggesting its potential role in tumorigenesis and cancer progression. 3. **Neurological disorders:** KIF11 has been implicated in various neurological disorders, including autism spectrum disorder and schizophrenia, highlighting its potential role in neural development and function. 4. **Neurodegenerative diseases:** Dysregulation of KIF11 has been observed in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, suggesting its potential role in disease pathogenesis. In conclusion, KIF11 is a multifunctional protein that plays a crucial role in various cellular processes, including immune system regulation, cell division, and microtubule dynamics. Its dysregulation has been implicated in various diseases, highlighting its importance as a potential therapeutic target for the treatment of immunodeficiency disorders, cancer, neurological disorders, and neurodegenerative diseases.

Genular Protein ID: 593690850

Symbol: KIF11_HUMAN

Name: Kinesin-like protein KIF11

UniProtKB Accession Codes:

P52732 A0AV49 B2RMV3 Q15716 Q5VWX0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 12 DrugCentral 1 EMBL 7 EMDB 14 Ensembl 1 EvolutionaryTrace 1 GO 23 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 62 PDBsum 62 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8548803

Title: Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo.

PubMed ID: 8548803

DOI: 10.1016/0092-8674(95)90142-6

PubMed ID: 9701554

Title: Expanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle.

PubMed ID: 9701554

DOI: 10.1242/jcs.111.17.2551

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7776974

Title: Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

PubMed ID: 7776974

DOI: 10.1210/mend.9.2.7776974

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19001501

Title: The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation.

PubMed ID: 19001501

DOI: 10.1242/jcs.035360

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21303978

Title: Tumor suppressor RARRES1 interacts with cytoplasmic carboxypeptidase AGBL2 to regulate the alpha-tubulin tyrosination cycle.

PubMed ID: 21303978

DOI: 10.1158/0008-5472.can-10-2294

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23857769

Title: Kinesin-5/Eg5 is important for transport of CARTS from the trans-Golgi network to the cell surface.

PubMed ID: 23857769

DOI: 10.1083/jcb.201303163

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 37728657

Title: UHRF1 promotes spindle assembly and chromosome congression by catalyzing EG5 polyubiquitination.

PubMed ID: 37728657

DOI: 10.1083/jcb.202210093

PubMed ID: 11328809

Title: Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker.

PubMed ID: 11328809

DOI: 10.1074/jbc.m100395200

PubMed ID: 17707232

Title: A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.

PubMed ID: 17707232

DOI: 10.1016/j.molcel.2007.07.024

PubMed ID: 22284827

Title: Mutations in KIF11 cause autosomal-dominant microcephaly variably associated with congenital lymphedema and chorioretinopathy.

PubMed ID: 22284827

DOI: 10.1016/j.ajhg.2011.12.018

Sequence Information:

  • Length: 1056
  • Mass: 119159
  • Checksum: C7F2606FE68DA8EA
  • Sequence:
    • MASQPNSSAK KKEEKGKNIQ VVVRCRPFNL AERKASAHSI VECDPVRKEV SVRTGGLADK 
SSRKTYTFDM VFGASTKQID VYRSVVCPIL DEVIMGYNCT IFAYGQTGTG KTFTMEGERS 
PNEEYTWEED PLAGIIPRTL HQIFEKLTDN GTEFSVKVSL LEIYNEELFD LLNPSSDVSE 
RLQMFDDPRN KRGVIIKGLE EITVHNKDEV YQILEKGAAK RTTAATLMNA YSSRSHSVFS 
VTIHMKETTI DGEELVKIGK LNLVDLAGSE NIGRSGAVDK RAREAGNINQ SLLTLGRVIT 
ALVERTPHVP YRESKLTRIL QDSLGGRTRT SIIATISPAS LNLEETLSTL EYAHRAKNIL 
NKPEVNQKLT KKALIKEYTE EIERLKRDLA AAREKNGVYI SEENFRVMSG KLTVQEEQIV 
ELIEKIGAVE EELNRVTELF MDNKNELDQC KSDLQNKTQE LETTQKHLQE TKLQLVKEEY 
ITSALESTEE KLHDAASKLL NTVEETTKDV SGLHSKLDRK KAVDQHNAEA QDIFGKNLNS 
LFNNMEELIK DGSSKQKAML EVHKTLFGNL LSSSVSALDT ITTVALGSLT SIPENVSTHV 
SQIFNMILKE QSLAAESKTV LQELINVLKT DLLSSLEMIL SPTVVSILKI NSQLKHIFKT 
SLTVADKIED QKKELDGFLS ILCNNLHELQ ENTICSLVES QKQCGNLTED LKTIKQTHSQ 
ELCKLMNLWT ERFCALEEKC ENIQKPLSSV QENIQQKSKD IVNKMTFHSQ KFCADSDGFS 
QELRNFNQEG TKLVEESVKH SDKLNGNLEK ISQETEQRCE SLNTRTVYFS EQWVSSLNER 
EQELHNLLEV VSQCCEASSS DITEKSDGRK AAHEKQHNIF LDQMTIDEDK LIAQNLELNE 
TIKIGLTKLN CFLEQDLKLD IPTGTTPQRK SYLYPSTLVR TEPREHLLDQ LKRKQPELLM 
MLNCSENNKE ETIPDVDVEE AVLGQYTEEP LSQEPSVDAG VDCSSIGGVP FFQHKKSHGK 
DKENRGINTL ERSKVEETTE HLVTKSRLPL RAQINL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.