Details for: RPSA

Gene ID: 3921

Symbol: RPSA

Ensembl ID: ENSG00000168028

Description: ribosomal protein SA

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 556.3693
    Cell Significance Index: -229.2000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 471.8689
    Cell Significance Index: -222.7800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 450.1879
    Cell Significance Index: -231.5700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 332.9696
    Cell Significance Index: -223.4300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 36.1460
    Cell Significance Index: -96.8300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 18.7593
    Cell Significance Index: 479.2400
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 17.6839
    Cell Significance Index: 268.5800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 13.4166
    Cell Significance Index: 358.8900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 10.0508
    Cell Significance Index: 210.3800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 9.7252
    Cell Significance Index: 337.9500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 9.4653
    Cell Significance Index: 102.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 9.3596
    Cell Significance Index: 956.0900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 9.0297
    Cell Significance Index: 115.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 8.9453
    Cell Significance Index: 420.4200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 8.1927
    Cell Significance Index: 240.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 8.0928
    Cell Significance Index: 212.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 8.0295
    Cell Significance Index: 987.3000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 7.8631
    Cell Significance Index: 556.1100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 7.6049
    Cell Significance Index: 982.5000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 7.5714
    Cell Significance Index: 1364.8800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 7.5460
    Cell Significance Index: 1036.2800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 7.2619
    Cell Significance Index: 167.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 6.9064
    Cell Significance Index: 814.4800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 6.4952
    Cell Significance Index: 302.8400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 6.4876
    Cell Significance Index: 2868.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 6.4152
    Cell Significance Index: 3503.5100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 6.3844
    Cell Significance Index: 411.8900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 6.1589
    Cell Significance Index: 176.5500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 5.4989
    Cell Significance Index: 62.4700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 5.3950
    Cell Significance Index: 402.0900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 4.9080
    Cell Significance Index: 86.7300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 4.6418
    Cell Significance Index: 42.7500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.5821
    Cell Significance Index: 36.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.4270
    Cell Significance Index: 120.5000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 4.0171
    Cell Significance Index: 685.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 3.2414
    Cell Significance Index: 2926.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.7894
    Cell Significance Index: 74.4800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 2.5486
    Cell Significance Index: 1929.0700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.4047
    Cell Significance Index: 308.2700
  • Cell Name: theca cell (CL0000503)
    Fold Change: 2.1277
    Cell Significance Index: 12.5000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.0706
    Cell Significance Index: 410.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.0577
    Cell Significance Index: 108.0400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6527
    Cell Significance Index: 163.4900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8077
    Cell Significance Index: 41.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7175
    Cell Significance Index: 136.5500
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.4821
    Cell Significance Index: 3.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.4169
    Cell Significance Index: 305.6600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2856
    Cell Significance Index: 57.3000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.1473
    Cell Significance Index: 42.4000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1452
    Cell Significance Index: 2.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0398
    Cell Significance Index: 6.4800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0046
    Cell Significance Index: 0.2600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0086
    Cell Significance Index: -3.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0532
    Cell Significance Index: -100.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0787
    Cell Significance Index: -58.2900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.1144
    Cell Significance Index: -211.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1289
    Cell Significance Index: -72.7000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.1469
    Cell Significance Index: -226.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1946
    Cell Significance Index: -264.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.2840
    Cell Significance Index: -180.3900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2851
    Cell Significance Index: -178.0600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3912
    Cell Significance Index: -7.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4017
    Cell Significance Index: -24.6900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.4414
    Cell Significance Index: -200.3300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.5115
    Cell Significance Index: -107.7300
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.5353
    Cell Significance Index: -4.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7465
    Cell Significance Index: -23.9100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8228
    Cell Significance Index: -94.2600
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.0285
    Cell Significance Index: -17.7300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.0607
    Cell Significance Index: -66.8500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.2148
    Cell Significance Index: -96.2100
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -1.3454
    Cell Significance Index: -8.2800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -1.3623
    Cell Significance Index: -198.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.7659
    Cell Significance Index: -62.0500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.8848
    Cell Significance Index: -215.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.9654
    Cell Significance Index: -49.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -2.0962
    Cell Significance Index: -144.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -2.1599
    Cell Significance Index: -224.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -2.2735
    Cell Significance Index: -103.0500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -2.6382
    Cell Significance Index: -202.4600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -3.0531
    Cell Significance Index: -205.2900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -3.1146
    Cell Significance Index: -190.9600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -3.2154
    Cell Significance Index: -69.6600
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: -3.3820
    Cell Significance Index: -9.0600
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -3.4331
    Cell Significance Index: -18.7200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -3.4382
    Cell Significance Index: -46.9100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -3.7172
    Cell Significance Index: -107.1000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -3.7207
    Cell Significance Index: -22.4800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -4.2035
    Cell Significance Index: -123.8100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -4.7523
    Cell Significance Index: -56.6500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -4.8427
    Cell Significance Index: -124.4800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -4.9492
    Cell Significance Index: -181.6800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -5.1067
    Cell Significance Index: -31.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -5.1989
    Cell Significance Index: -229.9600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -5.2144
    Cell Significance Index: -43.8000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -5.4558
    Cell Significance Index: -81.7500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -5.8332
    Cell Significance Index: -190.9800
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -6.0391
    Cell Significance Index: -125.9500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -6.1081
    Cell Significance Index: -213.9800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -6.1409
    Cell Significance Index: -232.5400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RPSA is a small, acidic protein (44 kDa) that is part of the 40S ribosomal subunit, which is responsible for the initiation of protein synthesis in eukaryotic cells. It is highly conserved across species and is essential for the accurate translation of mRNAs. RPSA is specifically involved in the binding of the cap-binding complex and eIFs to mRNA, allowing for the recruitment of the 40S subunit to the mRNA and the initiation of translation. **Pathways and Functions** RPSA is involved in several key pathways, including: 1. **Translation Initiation**: RPSA plays a crucial role in the binding of the cap-binding complex and eIFs to mRNA, allowing for the recruitment of the 40S subunit and the initiation of translation. 2. **Cell Adhesion**: RPSA has been shown to interact with laminin, a protein involved in cell adhesion, and regulate cell adhesion and migration. 3. **Response to Stress**: RPSA has been implicated in the response to stress, including amino acid starvation and viral infections. 4. **Cytoplasmic Translation**: RPSA is involved in the regulation of cytoplasmic translation, including the assembly of the 40S subunit and the recruitment of ribosomes to mRNA. **Clinical Significance** Dysregulation of RPSA has been implicated in various diseases, including: 1. **Cancer**: RPSA has been shown to be overexpressed in several types of cancer, including breast and lung cancer. 2. **Infectious Diseases**: RPSA has been implicated in the translation of viral mRNAs, including those of influenza and SARS-CoV-2. 3. **Neurological Disorders**: RPSA has been implicated in the regulation of protein synthesis in the nervous system, and its dysregulation has been linked to neurological disorders such as Alzheimer's disease and Parkinson's disease. In conclusion, RPSA is a critical component of the 40S ribosomal subunit, playing a vital role in the initiation and elongation of protein synthesis in eukaryotic cells. Its dysregulation has been implicated in various diseases, highlighting its importance as a potential therapeutic target.

Genular Protein ID: 316930295

Symbol: RSSA_HUMAN

Name: 40S ribosomal protein SA

UniProtKB Accession Codes:

P08865 P11085 P12030 Q16471 Q6IPD1 Q6IPD2 Q6NSD1 Q6NXQ8 Q86VC0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 27 EMDB 76 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HAMAP 2 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 94 PDBsum 94 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 18 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2970639

Title: Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein.

PubMed ID: 2970639

DOI: 10.1073/pnas.85.17.6394

PubMed ID: 2543954

Title: Characteristics of a multicopy gene family predominantly consisting of processed pseudogenes.

PubMed ID: 2543954

DOI: 10.1093/nar/17.10.3829

PubMed ID: 1534510

Title: Cloning of 67-kDa laminin receptor cDNA and gene expression in normal and malignant cell lines of the human lung.

PubMed ID: 1534510

DOI: 10.1016/0304-3835(92)90096-e

PubMed ID: 8760291

Title: Isolation from a multigene family of the active human gene of the metastasis-associated multifunctional protein 37LRP/p40 at chromosome 3p21.3.

PubMed ID: 8760291

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8706699

Title: Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry.

PubMed ID: 8706699

DOI: 10.1111/j.1432-1033.1996.0144u.x

PubMed ID: 8586453

Title: The gene for human E2 small nucleolar RNA resides in an intron of a laminin-binding protein gene.

PubMed ID: 8586453

PubMed ID: 2429301

Title: Altered levels of laminin receptor mRNA in various human carcinoma cells that have different abilities to bind laminin.

PubMed ID: 2429301

DOI: 10.1073/pnas.83.19.7137

PubMed ID: 9582194

Title: A map of 75 human ribosomal protein genes.

PubMed ID: 9582194

DOI: 10.1101/gr.8.5.509

PubMed ID: 6300843

Title: Laminin receptor on human breast carcinoma cells.

PubMed ID: 6300843

DOI: 10.1073/pnas.80.2.444

PubMed ID: 1834645

Title: Functional domains of the 67-kDa laminin receptor precursor.

PubMed ID: 1834645

DOI: 10.1016/s0021-9258(18)54943-7

PubMed ID: 1385835

Title: High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells.

PubMed ID: 1385835

DOI: 10.1128/jvi.66.8.4992-5001.1992

PubMed ID: 8433567

Title: Interaction between the 67 kilodalton metastasis-associated laminin receptor and laminin.

PubMed ID: 8433567

DOI: 10.1038/ki.1993.7

PubMed ID: 8764073

Title: A putative receptor for Venezuelan equine encephalitis virus from mosquito cells.

PubMed ID: 8764073

DOI: 10.1128/jvi.70.8.5592-5599.1996

PubMed ID: 9396609

Title: The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells.

PubMed ID: 9396609

DOI: 10.1038/nm1297-1383

PubMed ID: 9581863

Title: Formation of the 67-kDa laminin receptor by acylation of the precursor.

PubMed ID: 9581863

DOI: 10.1002/(sici)1097-4644(19980601)69:3<244::aid-jcb2>3.0.co;2-r

PubMed ID: 9718729

Title: The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution.

PubMed ID: 9718729

DOI: 10.1093/oxfordjournals.molbev.a026000

PubMed ID: 10079194

Title: Ribosome-associated protein LBP/p40 binds to S21 protein of 40S ribosome: analysis using a yeast two-hybrid system.

PubMed ID: 10079194

DOI: 10.1006/bbrc.1999.0343

PubMed ID: 10772861

Title: Phage display mapping for peptide 11 sensitive sequences binding to laminin-1.

PubMed ID: 10772861

DOI: 10.1006/jmbi.2000.3680

PubMed ID: 11689427

Title: The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein.

PubMed ID: 11689427

DOI: 10.1093/emboj/20.21.5863

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15507651

Title: Serotype-specific entry of dengue virus into liver cells: identification of the 37-kilodalton/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor.

PubMed ID: 15507651

DOI: 10.1128/jvi.78.22.12647-12656.2004

PubMed ID: 16263087

Title: The protein phosphatase-1 targeting subunit TIMAP regulates LAMR1 phosphorylation.

PubMed ID: 16263087

DOI: 10.1016/j.bbrc.2005.10.089

PubMed ID: 15516338

Title: 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells.

PubMed ID: 15516338

DOI: 10.1074/jbc.m410176200

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16973587

Title: The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9.

PubMed ID: 16973587

DOI: 10.1128/jvi.00878-06

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23579497

Title: Ribosomal protein SA haploinsufficiency in humans with isolated congenital asplenia.

PubMed ID: 23579497

DOI: 10.1126/science.1234864

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 18063583

Title: Crystal structure of the human laminin receptor precursor.

PubMed ID: 18063583

DOI: 10.1074/jbc.c700206200

Sequence Information:

  • Length: 295
  • Mass: 32854
  • Checksum: C68DDB16B759E79E
  • Sequence:
    • MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL 
AARAIVAIEN PADVSVISSR NTGQRAVLKF AAATGATPIA GRFTPGTFTN QIQAAFREPR 
LLVVTDPRAD HQPLTEASYV NLPTIALCNT DSPLRYVDIA IPCNNKGAHS VGLMWWMLAR 
EVLRMRGTIS REHPWEVMPD LYFYRDPEEI EKEEQAAAEK AVTKEEFQGE WTAPAPEFTA 
TQPEVADWSE GVQVPSVPIQ QFPTEDWSAQ PATEDWSAAP TAQATEWVGA TTDWS

Genular Protein ID: 3439189801

Symbol: A0A0C4DG17_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DG17

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 8 GeneTree 1 HAMAP 2 HAMAP-Rule 1 HGNC 1 IntAct 1 InterPro 7 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 300
  • Mass: 33314
  • Checksum: 65E68AA2EE32128E
  • Sequence:
    • MSGALDVLQM KEEDVLKFLA AGTHLGGTNL DFQMEQYIYK RKSDGIYIIN LKRTWEKLLL 
AARAIVAIEN PADVSVISSR NTGQVCGTVR AVLKFAAATG ATPIAGRFTP GTFTNQIQAA 
FREPRLLVVT DPRADHQPLT EASYVNLPTI ALCNTDSPLR YVDIAIPCNN KGAHSVGLMW 
WMLAREVLRM RGTISREHPW EVMPDLYFYR DPEEIEKEEQ AAAEKAVTKE EFQGEWTAPA 
PEFTATQPEV ADWSEGVQVP SVPIQQFPTE DWSAQPATED WSAAPTAQAT EWVGATTDWS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.