Details for: LDHB

Gene ID: 3945

Symbol: LDHB

Ensembl ID: ENSG00000111716

Description: lactate dehydrogenase B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 637.1137
    Cell Significance Index: -99.1000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 286.0801
    Cell Significance Index: -117.8500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 245.2117
    Cell Significance Index: -115.7700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 244.1617
    Cell Significance Index: -61.9300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 232.9285
    Cell Significance Index: -119.8200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 173.2879
    Cell Significance Index: -116.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 90.4453
    Cell Significance Index: -111.5200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 30.2645
    Cell Significance Index: -119.4300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 27.0974
    Cell Significance Index: -72.5900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 26.9286
    Cell Significance Index: -82.7100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 14.8054
    Cell Significance Index: 118.2100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 8.9483
    Cell Significance Index: 97.2800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 7.8564
    Cell Significance Index: 100.6200
  • Cell Name: theca cell (CL0000503)
    Fold Change: 7.2834
    Cell Significance Index: 42.7900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 6.8701
    Cell Significance Index: 180.6500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 6.8119
    Cell Significance Index: 357.6500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 6.7422
    Cell Significance Index: 234.2900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 6.7212
    Cell Significance Index: 140.6900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 6.7085
    Cell Significance Index: 197.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 4.9452
    Cell Significance Index: 608.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 4.6655
    Cell Significance Index: 640.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 4.5858
    Cell Significance Index: 2504.4000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 4.3720
    Cell Significance Index: 788.1300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 4.3481
    Cell Significance Index: 40.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 3.8909
    Cell Significance Index: 1119.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.3408
    Cell Significance Index: 89.2100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 3.2631
    Cell Significance Index: 258.4400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.1742
    Cell Significance Index: 374.3300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 3.0001
    Cell Significance Index: 387.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.9968
    Cell Significance Index: 223.3500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.9124
    Cell Significance Index: 136.8800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.8976
    Cell Significance Index: 186.9400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.9450
    Cell Significance Index: 249.3400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.7867
    Cell Significance Index: 92.8200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 1.7211
    Cell Significance Index: 1261.8800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.4690
    Cell Significance Index: 238.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.4475
    Cell Significance Index: 247.1700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3344
    Cell Significance Index: 36.3200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.2121
    Cell Significance Index: 535.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9818
    Cell Significance Index: 196.9500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.9639
    Cell Significance Index: 14.2300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.8840
    Cell Significance Index: 15.1500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8535
    Cell Significance Index: 65.5000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6806
    Cell Significance Index: 129.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.5698
    Cell Significance Index: 431.3200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5367
    Cell Significance Index: 192.5000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4347
    Cell Significance Index: 12.4600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4076
    Cell Significance Index: 28.8300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3485
    Cell Significance Index: 24.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1763
    Cell Significance Index: 3.8200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1207
    Cell Significance Index: 2.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0498
    Cell Significance Index: -1.7500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0563
    Cell Significance Index: -106.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0653
    Cell Significance Index: -6.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0725
    Cell Significance Index: -53.6900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0741
    Cell Significance Index: -136.6400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0891
    Cell Significance Index: -137.2200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1022
    Cell Significance Index: -138.9400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1429
    Cell Significance Index: -89.2500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1575
    Cell Significance Index: -88.8000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1719
    Cell Significance Index: -109.1700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1826
    Cell Significance Index: -5.2600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2569
    Cell Significance Index: -116.6000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3350
    Cell Significance Index: -18.8000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3554
    Cell Significance Index: -9.0800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.3648
    Cell Significance Index: -36.0900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3679
    Cell Significance Index: -4.1800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4594
    Cell Significance Index: -12.3100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.5096
    Cell Significance Index: -101.1400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.5172
    Cell Significance Index: -108.9300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.5421
    Cell Significance Index: -33.3200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6031
    Cell Significance Index: -38.0100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6343
    Cell Significance Index: -73.9200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.7704
    Cell Significance Index: -111.9800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.8069
    Cell Significance Index: -37.6200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8249
    Cell Significance Index: -94.5100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.8824
    Cell Significance Index: -100.7300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.8995
    Cell Significance Index: -28.8100
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: -0.9535
    Cell Significance Index: -5.4200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.9765
    Cell Significance Index: -11.6400
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -1.0053
    Cell Significance Index: -17.3300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.0493
    Cell Significance Index: -47.5600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.1547
    Cell Significance Index: -120.2300
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: -1.1649
    Cell Significance Index: -6.1300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -1.1890
    Cell Significance Index: -27.4700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.3298
    Cell Significance Index: -23.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.4134
    Cell Significance Index: -39.5000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.4428
    Cell Significance Index: -38.6000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.5662
    Cell Significance Index: -96.0200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.7811
    Cell Significance Index: -119.7600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.7979
    Cell Significance Index: -38.2900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.8993
    Cell Significance Index: -48.8200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.9185
    Cell Significance Index: -19.8600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -2.0826
    Cell Significance Index: -108.4800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -2.0929
    Cell Significance Index: -17.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -2.1259
    Cell Significance Index: -94.0400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.1515
    Cell Significance Index: -63.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -2.1714
    Cell Significance Index: -54.2800
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -2.4249
    Cell Significance Index: -13.2200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -2.4839
    Cell Significance Index: -33.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LDHB is a homodimeric enzyme consisting of two identical subunits, each containing a flavin adenine dinucleotide (FAD) cofactor. The enzyme is primarily localized in the cytosol and mitochondria, where it catalyzes the conversion of pyruvate to lactate. LDHB has been shown to be highly expressed in various cell types, including hematopoietic stem cells, renal intercalated cells, and epithelial cells. The enzyme's activity is tightly regulated by factors such as pH, oxygen levels, and metabolic substrates. **Pathways and Functions:** LDHB is integral to several metabolic pathways, including: 1. **Glycolysis**: LDHB catalyzes the conversion of pyruvate to lactate, a key regulatory point in glycolysis. 2. **Lactate metabolism**: LDHB is involved in the regulation of lactate levels, which can influence energy production, redox balance, and pH homeostasis. 3. **Citric acid (TCA) cycle**: LDHB has been shown to interact with the TCA cycle, influencing the regulation of energy production and redox balance. 4. **Oxidoreductase complex**: LDHB is part of the oxidoreductase complex, which plays a crucial role in the regulation of redox balance and energy production. In addition to its metabolic functions, LDHB has been implicated in various cellular processes, including: 1. **Immune cell activation**: LDHB has been shown to be highly expressed in activated T cells and natural killer cells, suggesting a role in immune cell activation and function. 2. **Differentiation and survival**: LDHB has been implicated in the regulation of cellular differentiation and survival, particularly in hematopoietic stem cells and epithelial cells. **Clinical Significance:** LDHB has been implicated in various disease contexts, including: 1. **Cancer**: Elevated LDHB expression has been observed in various types of cancer, including breast, lung, and colon cancer, suggesting a potential role in tumorigenesis and tumor progression. 2. **Metabolic disorders**: LDHB has been implicated in metabolic disorders such as diabetes and obesity, where dysregulation of glycolysis and lactate metabolism can contribute to disease pathogenesis. 3. **Autoimmune diseases**: LDHB has been shown to be highly expressed in activated T cells in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis, suggesting a potential role in disease pathogenesis. In conclusion, LDHB is a multifaceted enzyme with a wide range of metabolic and immunological functions. Further research is needed to fully elucidate the role of LDHB in various disease contexts and to explore its potential as a therapeutic target.

Genular Protein ID: 3442828945

Symbol: LDHB_HUMAN

Name: L-lactate dehydrogenase B chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2930497

Title: Structure of the human lactate dehydrogenase B gene.

PubMed ID: 2930497

DOI: 10.1042/bj2570921

PubMed ID: 3435492

Title: The cDNA and protein sequences of human lactate dehydrogenase B.

PubMed ID: 3435492

DOI: 10.1042/bj2480933

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10508479

Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.

PubMed ID: 10508479

DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27618187

Title: Lactate metabolism is associated with mammalian mitochondria.

PubMed ID: 27618187

DOI: 10.1038/nchembio.2172

PubMed ID: 33406399

Title: An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism.

PubMed ID: 33406399

DOI: 10.1016/j.cmet.2020.12.008

PubMed ID: 33535099

Title:

PubMed ID: 33535099

DOI: 10.1016/j.cmet.2021.01.008

PubMed ID: 11276087

Title: Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase.

PubMed ID: 11276087

DOI: 10.1002/1097-0134(20010501)43:2<175::aid-prot1029>3.0.co;2-#

PubMed ID: 8314553

Title: Analysis of a genetic mutation in an electrophoretic variant of the human lactate dehydrogenase-B(H) subunit.

PubMed ID: 8314553

DOI: 10.1007/bf00217765

PubMed ID: 8462975

Title: Detection and characterization of new genetic mutations in individuals heterozygous for lactate dehydrogenase-B(H) deficiency using DNA conformation polymorphism analysis and silver staining.

PubMed ID: 8462975

DOI: 10.1007/bf00222718

PubMed ID: 1587525

Title: Molecular characterization of genetic mutations in human lactate dehydrogenase (LDH) B (H) variant.

PubMed ID: 1587525

DOI: 10.1007/bf00217116

PubMed ID: 2334429

Title: A missense mutation found in human lactate dehydrogenase-B (H) variant gene.

PubMed ID: 2334429

DOI: 10.1016/0006-291x(90)92373-8

PubMed ID: 8611651

Title: Arginine to tryptophan substitution in the active site of a human lactate dehydrogenase variant -- LDHB GUA1: postulated effects on subunit structure and catalysis.

PubMed ID: 8611651

DOI: 10.1016/0925-4439(95)00089-5

PubMed ID: 10211631

Title: A novel in-frame deletion mutation in a case of lactate dehydrogenase (LD) H subunit deficiency showing an atypical LD isoenzyme pattern in serum and erythrocytes.

PubMed ID: 10211631

DOI: 10.1016/s0009-9120(98)00097-6

PubMed ID: 10509905

Title: Genetic analyses in homozygous and heterozygous variants of lactate dehydrogenase-B (H) subunit--LD-B Matsumoto I and II (LD-B W323R).

PubMed ID: 10509905

DOI: 10.1016/s0009-8981(99)00127-8

PubMed ID: 9929983

Title: First case of missense mutation (LDH-H:R171P) in exon 4 of the lactate dehydrogenase gene detected in a Japanese patient.

PubMed ID: 9929983

DOI: 10.1007/s100380050111

PubMed ID: 11509017

Title: A novel missense mutation in human lactate dehydrogenase b-subunit gene.

PubMed ID: 11509017

DOI: 10.1006/mgme.2001.3203

Sequence Information:

  • Length: 334
  • Mass: 36638
  • Checksum: 3AD605DEED0D54A2
  • Sequence:
  • MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK 
    GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF 
    IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG 
    IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY 
    EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG 
    LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL

Genular Protein ID: 4074315222

Symbol: A0A5F9ZHM4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

Sequence Information:

  • Length: 341
  • Mass: 37406
  • Checksum: CD93C20D584617DA
  • Sequence:
  • MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK 
    GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF 
    IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG 
    IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY 
    EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG 
    LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDLXLVSSR L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.