Details for: LDHB
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: cord blood hematopoietic stem cell (CL2000095)
Fold Change: 8.6
Marker Score: 6492.5 - Cell Name: renal intercalated cell (CL0005010)
Fold Change: 4.49
Marker Score: 2393 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 4.37
Marker Score: 11724.5 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 4.32
Marker Score: 4506 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: 4.26
Marker Score: 225244 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 4.01
Marker Score: 14222 - Cell Name: mature T cell (CL0002419)
Fold Change: 4
Marker Score: 39632 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 3.97
Marker Score: 52382 - Cell Name: naive T cell (CL0000898)
Fold Change: 3.87
Marker Score: 2496 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 3.87
Marker Score: 16592 - Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
Fold Change: 3.84
Marker Score: 6586 - Cell Name: radial glial cell (CL0000681)
Fold Change: 3.82
Marker Score: 1408 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 3.71
Marker Score: 5708 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 3.59
Marker Score: 9060 - Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
Fold Change: 3.55
Marker Score: 6339 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.55
Marker Score: 4285 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.48
Marker Score: 22668 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 3.48
Marker Score: 2724 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 3.43
Marker Score: 1097 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 3.39
Marker Score: 25232 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 3.36
Marker Score: 1107 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.33
Marker Score: 8142 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 3.32
Marker Score: 3131 - Cell Name: theca cell (CL0000503)
Fold Change: 3.31
Marker Score: 2374 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 3.26
Marker Score: 5400 - Cell Name: ventricular cardiac muscle cell (CL2000046)
Fold Change: 3.24
Marker Score: 1346 - Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 3.23
Marker Score: 4575 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 3.18
Marker Score: 1589 - Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
Fold Change: 3.18
Marker Score: 7758 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 3.15
Marker Score: 20533 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 3.15
Marker Score: 1977 - Cell Name: cell in vitro (CL0001034)
Fold Change: 3.14
Marker Score: 108846 - Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
Fold Change: 3.12
Marker Score: 2255 - Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
Fold Change: 3.04
Marker Score: 2848 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 3.03
Marker Score: 3210 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 3
Marker Score: 3046 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 3
Marker Score: 2554 - Cell Name: memory regulatory T cell (CL0002678)
Fold Change: 3
Marker Score: 1045 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 2.99
Marker Score: 4235 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 2.96
Marker Score: 3562 - Cell Name: supporting cell (CL0000630)
Fold Change: 2.96
Marker Score: 5559 - Cell Name: mature gamma-delta T cell (CL0000800)
Fold Change: 2.92
Marker Score: 9227 - Cell Name: chondrocyte (CL0000138)
Fold Change: 2.89
Marker Score: 1301 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.89
Marker Score: 3081.5 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 2.88
Marker Score: 18397 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: 2.87
Marker Score: 1684 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.86
Marker Score: 5821 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.85
Marker Score: 5958 - Cell Name: motor neuron (CL0000100)
Fold Change: 2.84
Marker Score: 1685 - Cell Name: late pro-B cell (CL0002048)
Fold Change: 2.83
Marker Score: 3344 - Cell Name: pro-T cell (CL0000827)
Fold Change: 2.83
Marker Score: 11591 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 2.8
Marker Score: 24331 - Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
Fold Change: 2.8
Marker Score: 2048 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.78
Marker Score: 4560 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 2.78
Marker Score: 16490 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 2.78
Marker Score: 2613 - Cell Name: pneumocyte (CL0000322)
Fold Change: 2.77
Marker Score: 4447 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 2.77
Marker Score: 3602 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: 2.76
Marker Score: 7744.5 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 2.73
Marker Score: 7434 - Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 2.72
Marker Score: 1969 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.71
Marker Score: 1025.5 - Cell Name: neural crest cell (CL0011012)
Fold Change: 2.7
Marker Score: 2887 - Cell Name: naive regulatory T cell (CL0002677)
Fold Change: 2.7
Marker Score: 820 - Cell Name: type I NK T cell (CL0000921)
Fold Change: 2.7
Marker Score: 2115 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 2.69
Marker Score: 3025 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.69
Marker Score: 27083 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 2.68
Marker Score: 1267 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.68
Marker Score: 11562.5 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.68
Marker Score: 10330 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.67
Marker Score: 30102 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2.67
Marker Score: 4542.5 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.64
Marker Score: 6218 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 2.64
Marker Score: 2847 - Cell Name: basophil (CL0000767)
Fold Change: 2.64
Marker Score: 1253 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 2.63
Marker Score: 7274 - Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
Fold Change: 2.63
Marker Score: 2211 - Cell Name: malignant cell (CL0001064)
Fold Change: 2.62
Marker Score: 35254 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.62
Marker Score: 89210 - Cell Name: B-1 B cell (CL0000819)
Fold Change: 2.62
Marker Score: 4559 - Cell Name: Unknown (CL0000548)
Fold Change: 2.6
Marker Score: 1892 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.59
Marker Score: 7683 - Cell Name: secretory cell (CL0000151)
Fold Change: 2.58
Marker Score: 4711 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.55
Marker Score: 1702 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 2.55
Marker Score: 2568 - Cell Name: germinal center B cell (CL0000844)
Fold Change: 2.55
Marker Score: 1550 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 2.54
Marker Score: 1056 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 2.53
Marker Score: 1200.5 - Cell Name: CD4-positive, CD25-positive, alpha-beta regulatory T cell (CL0000792)
Fold Change: 2.52
Marker Score: 669.5 - Cell Name: regulatory T cell (CL0000815)
Fold Change: 2.52
Marker Score: 2787 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 2.51
Marker Score: 805 - Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
Fold Change: 2.5
Marker Score: 2696 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.49
Marker Score: 596 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 2.49
Marker Score: 1773 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.49
Marker Score: 25223 - Cell Name: alternatively activated macrophage (CL0000890)
Fold Change: 2.49
Marker Score: 1036 - Cell Name: club cell (CL0000158)
Fold Change: 2.47
Marker Score: 2887 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 2.47
Marker Score: 830 - Cell Name: memory B cell (CL0000787)
Fold Change: 2.46
Marker Score: 1864 - Cell Name: granulocyte (CL0000094)
Fold Change: 2.44
Marker Score: 1094
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Other Information
Genular Protein ID: 3442828945
Symbol: LDHB_HUMAN
Name: L-lactate dehydrogenase B chain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2930497
Title: Structure of the human lactate dehydrogenase B gene.
PubMed ID: 2930497
DOI: 10.1042/bj2570921
PubMed ID: 3435492
Title: The cDNA and protein sequences of human lactate dehydrogenase B.
PubMed ID: 3435492
DOI: 10.1042/bj2480933
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10508479
Title: Antigens recognized by autologous antibody in patients with renal-cell carcinoma.
PubMed ID: 10508479
DOI: 10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5
PubMed ID: 15592455
Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.
PubMed ID: 15592455
DOI: 10.1038/nbt1046
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 27618187
Title: Lactate metabolism is associated with mammalian mitochondria.
PubMed ID: 27618187
PubMed ID: 33406399
Title: An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism.
PubMed ID: 33406399
PubMed ID: 33535099
PubMed ID: 11276087
Title: Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase.
PubMed ID: 11276087
DOI: 10.1002/1097-0134(20010501)43:2<175::aid-prot1029>3.0.co;2-#
PubMed ID: 8314553
Title: Analysis of a genetic mutation in an electrophoretic variant of the human lactate dehydrogenase-B(H) subunit.
PubMed ID: 8314553
DOI: 10.1007/bf00217765
PubMed ID: 8462975
Title: Detection and characterization of new genetic mutations in individuals heterozygous for lactate dehydrogenase-B(H) deficiency using DNA conformation polymorphism analysis and silver staining.
PubMed ID: 8462975
DOI: 10.1007/bf00222718
PubMed ID: 1587525
Title: Molecular characterization of genetic mutations in human lactate dehydrogenase (LDH) B (H) variant.
PubMed ID: 1587525
DOI: 10.1007/bf00217116
PubMed ID: 2334429
Title: A missense mutation found in human lactate dehydrogenase-B (H) variant gene.
PubMed ID: 2334429
PubMed ID: 8611651
Title: Arginine to tryptophan substitution in the active site of a human lactate dehydrogenase variant -- LDHB GUA1: postulated effects on subunit structure and catalysis.
PubMed ID: 8611651
PubMed ID: 10211631
Title: A novel in-frame deletion mutation in a case of lactate dehydrogenase (LD) H subunit deficiency showing an atypical LD isoenzyme pattern in serum and erythrocytes.
PubMed ID: 10211631
PubMed ID: 9929983
Title: First case of missense mutation (LDH-H:R171P) in exon 4 of the lactate dehydrogenase gene detected in a Japanese patient.
PubMed ID: 9929983
PubMed ID: 11509017
Title: A novel missense mutation in human lactate dehydrogenase b-subunit gene.
PubMed ID: 11509017
Sequence Information:
- Length: 334
- Mass: 36638
- Checksum: 3AD605DEED0D54A2
- Sequence:
MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL
Genular Protein ID: 4074315222
Symbol: A0A5F9ZHM4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
Sequence Information:
- Length: 341
- Mass: 37406
- Checksum: CD93C20D584617DA
- Sequence:
MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDLXLVSSR L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.