Details for: LNPEP
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 311.0671
Cell Significance Index: -48.3900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 183.0917
Cell Significance Index: -46.4400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 111.4688
Cell Significance Index: -45.2900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 108.4888
Cell Significance Index: -51.2200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 96.5813
Cell Significance Index: -49.6800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 47.5625
Cell Significance Index: -45.4100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 40.4759
Cell Significance Index: -49.9100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.6301
Cell Significance Index: -54.1500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 17.5224
Cell Significance Index: -46.9400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 12.7773
Cell Significance Index: -50.4200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.5678
Cell Significance Index: -20.9400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.6550
Cell Significance Index: 183.6100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.8498
Cell Significance Index: 141.9500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.4940
Cell Significance Index: 96.3900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.4729
Cell Significance Index: 160.2100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4604
Cell Significance Index: 289.8200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.4052
Cell Significance Index: 228.5400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.3692
Cell Significance Index: 274.6600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.3222
Cell Significance Index: 18.0400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.2440
Cell Significance Index: 146.7100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.2372
Cell Significance Index: 74.2800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.1722
Cell Significance Index: 30.1300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.1362
Cell Significance Index: 407.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.0298
Cell Significance Index: 126.6300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.9317
Cell Significance Index: 167.9600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.9048
Cell Significance Index: 50.7700 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.6453
Cell Significance Index: 12.6000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5873
Cell Significance Index: 406.1800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.5786
Cell Significance Index: 16.1700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5583
Cell Significance Index: 504.1500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.4318
Cell Significance Index: 190.9300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.4299
Cell Significance Index: 9.1900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3939
Cell Significance Index: 215.1100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3901
Cell Significance Index: 23.9800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.3799
Cell Significance Index: 9.2700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.3751
Cell Significance Index: 5.5400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.3228
Cell Significance Index: 44.3300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2416
Cell Significance Index: 4.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1829
Cell Significance Index: 34.8000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1795
Cell Significance Index: 12.7000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1691
Cell Significance Index: 16.7300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1645
Cell Significance Index: 309.8200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1610
Cell Significance Index: 4.6400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1554
Cell Significance Index: 98.7200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0581
Cell Significance Index: 26.3600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0503
Cell Significance Index: 3.3800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0429
Cell Significance Index: 79.1300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0415
Cell Significance Index: 63.8800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0399
Cell Significance Index: 1.8100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0093
Cell Significance Index: 6.8400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0074
Cell Significance Index: 0.9500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0003
Cell Significance Index: -0.4500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0389
Cell Significance Index: -1.7200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0453
Cell Significance Index: -6.5800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0484
Cell Significance Index: -35.8300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0548
Cell Significance Index: -41.5100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0614
Cell Significance Index: -1.6400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0862
Cell Significance Index: -48.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0952
Cell Significance Index: -59.4200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0968
Cell Significance Index: -9.8900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1068
Cell Significance Index: -4.0500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1138
Cell Significance Index: -5.9100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1378
Cell Significance Index: -23.5300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1395
Cell Significance Index: -6.5600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1417
Cell Significance Index: -3.0700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1510
Cell Significance Index: -43.4600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1654
Cell Significance Index: -7.7100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1778
Cell Significance Index: -20.7200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2306
Cell Significance Index: -5.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2618
Cell Significance Index: -33.8200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2627
Cell Significance Index: -55.3300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2658
Cell Significance Index: -16.7500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2951
Cell Significance Index: -30.7300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3232
Cell Significance Index: -37.0300 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -0.3555
Cell Significance Index: -2.7400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3830
Cell Significance Index: -10.4300 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4189
Cell Significance Index: -11.2100 - Cell Name: peg cell (CL4033014)
Fold Change: -0.4354
Cell Significance Index: -10.0600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.4413
Cell Significance Index: -12.9600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4478
Cell Significance Index: -12.7800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4677
Cell Significance Index: -9.9600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5030
Cell Significance Index: -37.4900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5361
Cell Significance Index: -17.1700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.5755
Cell Significance Index: -15.4200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5780
Cell Significance Index: -45.7800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5985
Cell Significance Index: -31.1800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.6556
Cell Significance Index: -34.4200 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -0.6685
Cell Significance Index: -2.9100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7045
Cell Significance Index: -43.1900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.7396
Cell Significance Index: -13.6700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.7827
Cell Significance Index: -9.3300 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.8140
Cell Significance Index: -10.1500 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.9014
Cell Significance Index: -11.3500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.9131
Cell Significance Index: -13.7600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.9490
Cell Significance Index: -31.0700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.9758
Cell Significance Index: -20.7100 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.9888
Cell Significance Index: -12.4800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.0128
Cell Significance Index: -16.9500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.0401
Cell Significance Index: -33.1300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.0515
Cell Significance Index: -36.5400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3223605661
Symbol: LCAP_HUMAN
Name: Leucyl-cystinyl aminopeptidase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8550619
Title: Human placental leucine aminopeptidase/oxytocinase. A new member of type II membrane-spanning zinc metallopeptidase family.
PubMed ID: 8550619
DOI: 10.1074/jbc.271.1.56
PubMed ID: 9177475
Title: The complete amino acid sequence of human placental oxytocinase.
PubMed ID: 9177475
PubMed ID: 10759854
Title: Structure of the human oxytocinase/insulin-regulated aminopeptidase gene and localization to chromosome 5q21.
PubMed ID: 10759854
PubMed ID: 11389728
Title: Expression of placental leucine aminopeptidase/oxytocinase in neuronal cells and its action on neuronal peptides.
PubMed ID: 11389728
PubMed ID: 8119729
Title: Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules.
PubMed ID: 8119729
DOI: 10.1007/bf00188785
PubMed ID: 1731608
Title: Identification of human placental leucine aminopeptidase as oxytocinase.
PubMed ID: 1731608
PubMed ID: 11707427
Title: Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase.
PubMed ID: 11707427
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 1025
- Mass: 117349
- Checksum: F84C0EA9D48DC2C0
- Sequence:
MEPFTNDRLQ LPRNMIENSM FEEEPDVVDL AKEPCLHPLE PDEVEYEPRG SRLLVRGLGE HEMEEDEEDY ESSAKLLGMS FMNRSSGLRN SATGYRQSPD GACSVPSART MVVCAFVIVV AVSVIMVIYL LPRCTFTKEG CHKKNQSIGL IQPFATNGKL FPWAQIRLPT AVVPLRYELS LHPNLTSMTF RGSVTISVQA LQVTWNIILH STGHNISRVT FMSAVSSQEK QAEILEYAYH GQIAIVAPEA LLAGHNYTLK IEYSANISSS YYGFYGFSYT DESNEKKYFA ATQFEPLAAR SAFPCFDEPA FKATFIIKII RDEQYTALSN MPKKSSVVLD DGLVQDEFSE SVKMSTYLVA FIVGEMKNLS QDVNGTLVSI YAVPEKIGQV HYALETTVKL LEFFQNYFEI QYPLKKLDLV AIPDFEAGAM ENWGLLTFRE ETLLYDSNTS SMADRKLVTK IIAHELAHQW FGNLVTMKWW NDLWLNEGFA TFMEYFSLEK IFKELSSYED FLDARFKTMK KDSLNSSHPI SSSVQSSEQI EEMFDSLSYF KGSSLLLMLK TYLSEDVFQH AVVLYLHNHS YASIQSDDLW DSFNEVTNQT LDVKRMMKTW TLQKGFPLVT VQKKGKELFI QQERFFLNMK PEIQPSDTSY LWHIPLSYVT EGRNYSKYQS VSLLDKKSGV INLTEEVLWV KVNINMNGYY IVHYADDDWE ALIHQLKINP YVLSDKDRAN LINNIFELAG LGKVPLKRAF DLINYLGNEN HTAPITEALF QTDLIYNLLE KLGYMDLASR LVTRVFKLLQ NQIQQQTWTD EGTPSMRELR SALLEFACTH NLGNCSTTAM KLFDDWMASN GTQSLPTDVM TTVFKVGAKT DKGWSFLLGK YISIGSEAEK NKILEALASS EDVRKLYWLM KSSLNGDNFR TQKLSFIIRT VGRHFPGHLL AWDFVKENWN KLVQKFPLGS YTIQNIVAGS TYLFSTKTHL SEVQAFFENQ SEATFRLRCV QEALEVIQLN IQWMEKNLKS LTWWL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.