Details for: LRPAP1

Gene ID: 4043

Symbol: LRPAP1

Ensembl ID: ENSG00000163956

Description: LDL receptor related protein associated protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 390.1116
    Cell Significance Index: -60.6800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 225.7500
    Cell Significance Index: -57.2600
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 163.5402
    Cell Significance Index: -67.3700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 149.0926
    Cell Significance Index: -70.3900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 147.3574
    Cell Significance Index: -59.8700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 129.5527
    Cell Significance Index: -66.6400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 105.6001
    Cell Significance Index: -70.8600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 63.0117
    Cell Significance Index: -60.1600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 53.0757
    Cell Significance Index: -65.4400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.4901
    Cell Significance Index: -54.8900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.9258
    Cell Significance Index: -66.7900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 15.7743
    Cell Significance Index: -48.4500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.9138
    Cell Significance Index: -17.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 5.7343
    Cell Significance Index: 267.3600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.4770
    Cell Significance Index: 94.6400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.3463
    Cell Significance Index: 459.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.3064
    Cell Significance Index: 415.7700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.2757
    Cell Significance Index: 279.8200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.2520
    Cell Significance Index: 1229.8900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.9330
    Cell Significance Index: 17.8000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.5535
    Cell Significance Index: 35.8900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.4044
    Cell Significance Index: 180.0300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.4022
    Cell Significance Index: 37.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.3889
    Cell Significance Index: 72.1500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 1.3118
    Cell Significance Index: 35.0900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.0602
    Cell Significance Index: 79.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.9557
    Cell Significance Index: 49.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9440
    Cell Significance Index: 153.5300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9214
    Cell Significance Index: 184.8400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.8815
    Cell Significance Index: 150.5200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7938
    Cell Significance Index: 37.3100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7837
    Cell Significance Index: 346.4900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7639
    Cell Significance Index: 16.5500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.7628
    Cell Significance Index: 6.0900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7576
    Cell Significance Index: 150.3400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.7534
    Cell Significance Index: 19.8100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7242
    Cell Significance Index: 13.3900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6960
    Cell Significance Index: 628.4300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.6788
    Cell Significance Index: 48.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6681
    Cell Significance Index: 19.2500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6081
    Cell Significance Index: 31.9300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6032
    Cell Significance Index: 22.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5806
    Cell Significance Index: 208.2500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5048
    Cell Significance Index: 32.5700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4920
    Cell Significance Index: 63.5700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4811
    Cell Significance Index: 13.7900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4242
    Cell Significance Index: 41.9600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3705
    Cell Significance Index: 7.7600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.3470
    Cell Significance Index: 15.3500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2865
    Cell Significance Index: 3.2600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2268
    Cell Significance Index: 43.1700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2171
    Cell Significance Index: 7.6300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1646
    Cell Significance Index: 5.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0989
    Cell Significance Index: 6.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0886
    Cell Significance Index: 64.9900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0371
    Cell Significance Index: 4.3800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0264
    Cell Significance Index: 49.6700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0261
    Cell Significance Index: 1.1900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0229
    Cell Significance Index: 17.3500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0115
    Cell Significance Index: -7.9800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0130
    Cell Significance Index: -20.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0163
    Cell Significance Index: -12.0700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0202
    Cell Significance Index: -37.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0206
    Cell Significance Index: -0.3500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0227
    Cell Significance Index: -2.3200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0321
    Cell Significance Index: -20.0200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0456
    Cell Significance Index: -28.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0460
    Cell Significance Index: -62.5000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0701
    Cell Significance Index: -4.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0821
    Cell Significance Index: -37.2500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0832
    Cell Significance Index: -46.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1146
    Cell Significance Index: -24.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1468
    Cell Significance Index: -16.8200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1898
    Cell Significance Index: -54.6200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1975
    Cell Significance Index: -13.6600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2053
    Cell Significance Index: -6.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2835
    Cell Significance Index: -21.7500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2948
    Cell Significance Index: -8.2400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3139
    Cell Significance Index: -19.3000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3210
    Cell Significance Index: -46.6600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3693
    Cell Significance Index: -42.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3758
    Cell Significance Index: -43.7900
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -0.4421
    Cell Significance Index: -9.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4678
    Cell Significance Index: -26.2500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5511
    Cell Significance Index: -6.5700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.5629
    Cell Significance Index: -6.1200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5719
    Cell Significance Index: -9.8000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.5773
    Cell Significance Index: -38.8200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6110
    Cell Significance Index: -15.6100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6114
    Cell Significance Index: -63.6600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6326
    Cell Significance Index: -20.2600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6413
    Cell Significance Index: -16.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6919
    Cell Significance Index: -9.4400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7198
    Cell Significance Index: -57.0100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.0302
    Cell Significance Index: -26.4800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.1288
    Cell Significance Index: -19.9500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.1368
    Cell Significance Index: -24.2100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1398
    Cell Significance Index: -69.8800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -1.1949
    Cell Significance Index: -16.7600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.2280
    Cell Significance Index: -32.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LRPAP1 is a multifunctional protein that interacts with various receptors and proteins, influencing cellular processes such as amyloid-beta clearance, receptor internalization, and signaling transduction. Its ability to bind to low-density lipoprotein particles and amyloid-beta peptides positions it as a key player in the regulation of lipid metabolism and amyloid-beta clearance. The gene's expression in different cell types and its involvement in multiple signaling pathways underscore its complexity and potential regulatory functions. **Pathways and Functions:** LRPAP1 is involved in several signaling pathways, including: 1. **Amyloid-beta clearance:** LRPAP1 facilitates the clearance of amyloid-beta peptides from the extracellular environment, potentially mitigating the progression of neurodegenerative diseases such as Alzheimer's. 2. **Receptor-mediated endocytosis:** LRPAP1 regulates the internalization of receptors, influencing cellular signaling and response to external stimuli. 3. **Signaling transduction:** LRPAP1 interacts with various receptors and proteins, modulating signaling pathways involved in cellular growth, differentiation, and survival. 4. **Negative regulation of amyloid-beta clearance:** LRPAP1 can inhibit the clearance of amyloid-beta peptides, contributing to the accumulation of these peptides in the extracellular environment. **Clinical Significance:** The involvement of LRPAP1 in amyloid-beta clearance and receptor-mediated endocytosis makes it a potential target for therapeutic interventions in neurodegenerative diseases. Additionally, the gene's expression in various cell types and its regulatory functions suggest its potential role in maintaining cellular homeostasis in different physiological and pathological contexts. Further research is necessary to elucidate the functional significance of LRPAP1 in human disease and to explore its potential as a therapeutic target. In conclusion, LRPAP1 is a complex gene that plays a multifaceted role in cellular processes, including amyloid-beta clearance, receptor-mediated endocytosis, and signaling transduction. Its involvement in various signaling pathways and its expression in different cell types underscore its potential regulatory functions and its relevance to human disease. Further research is necessary to fully elucidate the functional significance of LRPAP1 and to explore its potential as a therapeutic target.

Genular Protein ID: 1714195955

Symbol: AMRP_HUMAN

Name: Low density lipoprotein receptor-related protein-associated protein 1

UniProtKB Accession Codes:

P30533 D3DVR9 Q2M310 Q53HQ3 Q53HS6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 17 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1712782

Title: Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen.

PubMed ID: 1712782

DOI: 10.1016/s0021-9258(18)98848-4

PubMed ID: 9782079

Title: Analysis of the human LRPAP1 gene coding for the lipoprotein receptor-associated protein: identification of 22 polymorphisms and one mutation.

PubMed ID: 9782079

DOI: 10.1006/geno.1998.5413

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7789983

Title: Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein.

PubMed ID: 7789983

DOI: 10.1016/0888-7543(95)80050-v

PubMed ID: 1400426

Title: The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330.

PubMed ID: 1400426

DOI: 10.1016/s0021-9258(19)36811-5

PubMed ID: 7774585

Title: 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein.

PubMed ID: 7774585

DOI: 10.1002/j.1460-2075.1995.tb07221.x

PubMed ID: 8940146

Title: Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein.

PubMed ID: 8940146

DOI: 10.1074/jbc.271.49.31379

PubMed ID: 11294867

Title: Activation and functional characterization of the mosaic receptor SorLA/LR11.

PubMed ID: 11294867

DOI: 10.1074/jbc.m100857200

PubMed ID: 11384978

Title: The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein.

PubMed ID: 11384978

DOI: 10.1074/jbc.m102727200

PubMed ID: 12530537

Title: Characterization of the VPS10 domain of SorLA/LR11 as binding site for the neuropeptide HA.

PubMed ID: 12530537

DOI: 10.1515/bc.2002.193

PubMed ID: 15053742

Title: The mosaic receptor sorLA/LR11 binds components of the plasminogen-activating system and platelet-derived growth factor-BB similarly to LRP1 (low-density lipoprotein receptor-related protein), but mediates slow internalization of bound ligand.

PubMed ID: 15053742

DOI: 10.1042/bj20040149

PubMed ID: 15364913

Title: Functional organization of the sortilin Vps10p domain.

PubMed ID: 15364913

DOI: 10.1074/jbc.m408873200

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23830514

Title: Mutations in LRPAP1 are associated with severe myopia in humans.

PubMed ID: 23830514

DOI: 10.1016/j.ajhg.2013.06.002

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26858303

Title: Cytokine-like factor 1, an essential facilitator of cardiotrophin-like cytokine:ciliary neurotrophic factor receptor alpha signaling and sorLA-mediated turnover.

PubMed ID: 26858303

DOI: 10.1128/mcb.00917-15

PubMed ID: 32296178

Title: LRP1 is a master regulator of tau uptake and spread.

PubMed ID: 32296178

DOI: 10.1038/s41586-020-2156-5

PubMed ID: 9207124

Title: The solution structure of the N-terminal domain of alpha2-macroglobulin receptor-associated protein.

PubMed ID: 9207124

DOI: 10.1073/pnas.94.14.7521

PubMed ID: 12766414

Title: 1H, 13C and 15N resonance assignments of domain 1 of receptor associated protein.

PubMed ID: 12766414

DOI: 10.1023/a:1023534107920

PubMed ID: 16938309

Title: Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif.

PubMed ID: 16938309

DOI: 10.1016/j.jmb.2006.07.013

PubMed ID: 16630895

Title: Structure of an LDLR-RAP complex reveals a general mode for ligand recognition by lipoprotein receptors.

PubMed ID: 16630895

DOI: 10.1016/j.molcel.2006.02.021

PubMed ID: 16678114

Title: RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi.

PubMed ID: 16678114

DOI: 10.1016/j.molcel.2006.04.011

Sequence Information:

  • Length: 357
  • Mass: 41466
  • Checksum: D56A7DA754125CFA
  • Sequence:
    • MAPRRVRSFL RGLPALLLLL LFLGPWPAAS HGGKYSREKN QPKPSPKRES GEEFRMEKLN 
QLWEKAQRLH LPPVRLAELH ADLKIQERDE LAWKKLKLDG LDEDGEKEAR LIRNLNVILA 
KYGLDGKKDA RQVTSNSLSG TQEDGLDDPR LEKLWHKAKT SGKFSGEELD KLWREFLHHK 
EKVHEYNVLL ETLSRTEEIH ENVISPSDLS DIKGSVLHSR HTELKEKLRS INQGLDRLRR 
VSHQGYSTEA EFEEPRVIDL WDLAQSANLT DKELEAFREE LKHFEAKIEK HNHYQKQLEI 
AHEKLRHAES VGDGERVSRS REKHALLEGR TKELGYTVKK HLQDLSGRIS RARHNEL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.