Details for: ARNT

Gene ID: 405

Symbol: ARNT

Ensembl ID: ENSG00000143437

Description: aryl hydrocarbon receptor nuclear translocator

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.19
    Marker Score: 4,801
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.99
    Marker Score: 8,347
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.63
    Marker Score: 6,617
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.54
    Marker Score: 58,385
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.53
    Marker Score: 56,297
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.51
    Marker Score: 93,136
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.51
    Marker Score: 14,337
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.5
    Marker Score: 22,495
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.48
    Marker Score: 5,738
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.48
    Marker Score: 1,636
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.47
    Marker Score: 1,691
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.46
    Marker Score: 29,108
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.43
    Marker Score: 1,733
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.43
    Marker Score: 10,963
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.42
    Marker Score: 701
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.4
    Marker Score: 12,009
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.39
    Marker Score: 13,091
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.39
    Marker Score: 2,431
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.39
    Marker Score: 581
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.37
    Marker Score: 803
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.36
    Marker Score: 2,100
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.34
    Marker Score: 5,540
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.34
    Marker Score: 743
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.34
    Marker Score: 778
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.32
    Marker Score: 416
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.31
    Marker Score: 13,490
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.3
    Marker Score: 27,650
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.29
    Marker Score: 2,478
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.28
    Marker Score: 373
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.23
    Marker Score: 1,648
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.14
    Marker Score: 1,423
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.08
    Marker Score: 294
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.07
    Marker Score: 6,860
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.05
    Marker Score: 1,129
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.02
    Marker Score: 569
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1
    Marker Score: 597
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,703
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,927
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.99
    Marker Score: 4,276
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,392
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.98
    Marker Score: 15,328
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.95
    Marker Score: 434
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.94
    Marker Score: 304
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2,398
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.93
    Marker Score: 480
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 434
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.92
    Marker Score: 339
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2,706
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.89
    Marker Score: 232
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.89
    Marker Score: 19,986
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.89
    Marker Score: 303
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.89
    Marker Score: 30,278
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,295
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.87
    Marker Score: 424
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.87
    Marker Score: 277
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.87
    Marker Score: 13,930
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.86
    Marker Score: 1,759
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.86
    Marker Score: 198
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.86
    Marker Score: 2,112
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 309
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.86
    Marker Score: 818
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.86
    Marker Score: 426
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.85
    Marker Score: 4,871
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.85
    Marker Score: 913
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.85
    Marker Score: 4,547
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.83
    Marker Score: 890
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.82
    Marker Score: 635
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.82
    Marker Score: 3,810
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.82
    Marker Score: 307
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.82
    Marker Score: 984
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.81
    Marker Score: 1,907
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.81
    Marker Score: 293
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.79
    Marker Score: 316
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 600
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.78
    Marker Score: 245
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,259
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.77
    Marker Score: 191
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.77
    Marker Score: 4,634
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.76
    Marker Score: 939
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.74
    Marker Score: 682
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.74
    Marker Score: 1,838
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.73
    Marker Score: 481
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.73
    Marker Score: 629
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.72
    Marker Score: 1,971
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 373
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.72
    Marker Score: 1,018
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.71
    Marker Score: 2,998
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.71
    Marker Score: 212
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.7
    Marker Score: 265
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.7
    Marker Score: 421
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.7
    Marker Score: 282
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.69
    Marker Score: 474
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.68
    Marker Score: 2,668
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.68
    Marker Score: 619
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 173
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.67
    Marker Score: 378
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 0.67
    Marker Score: 351
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.67
    Marker Score: 707
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.67
    Marker Score: 363
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.66
    Marker Score: 415

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Basic Helix-Loop-Helix (bHLH) Domain**: ARNT contains a bHLH domain, which is characteristic of basic helix-loop-helix transcription factors. This domain is essential for dimerization with AhR and subsequent DNA binding. 2. **Aryl Hydrocarbon Receptor Binding**: ARNT forms a heterodimer with AhR, enabling the receptor to bind to specific DNA sequences, known as dioxin response elements (DREs). 3. **Heterodimerization with AhR**: ARNT's ability to form a heterodimer with AhR is crucial for the regulation of gene expression in response to ligands. 4. **Cellular Expression**: ARNT is highly expressed in various cell types, including neurons, pigmented epithelial cells, and muscle cells. **Pathways and Functions** 1. **Aryl Hydrocarbon Receptor Signaling**: ARNT plays a central role in AhR signaling, facilitating the binding of AhR to DNA and modulating gene expression in response to ligands. 2. **Cell Differentiation**: ARNT is involved in regulating cell differentiation, particularly in the development of neurons and muscle cells. 3. **Metabolism**: ARNT modulates metabolic pathways, including lipid metabolism, by regulating the expression of genes involved in these processes. 4. **Response to Hypoxia**: ARNT is involved in the regulation of cellular responses to hypoxia, including the expression of genes involved in angiogenesis and energy metabolism. 5. **Regulation of Gene Expression**: ARNT regulates gene expression by interacting with transcription factors, such as HIF-1α, and modulating the expression of target genes. **Clinical Significance** 1. **Cancer**: Dysregulation of ARNT has been implicated in various cancers, including lung, breast, and colon cancer, where it can contribute to tumorigenesis and metastasis. 2. **Neurological Disorders**: ARNT has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may contribute to the regulation of gene expression and cellular responses to stress. 3. **Metabolic Disorders**: ARNT's role in lipid metabolism and energy homeostasis makes it a potential target for the treatment of metabolic disorders, such as obesity and type 2 diabetes. 4. **Toxicology**: ARNT's role in xenobiotic metabolism and response to toxins makes it a potential biomarker for exposure to environmental toxins. In conclusion, ARNT plays a critical role in regulating various cellular processes, including cell differentiation, metabolism, and response to hypoxia. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of ARNT and its potential as a therapeutic target.

Genular Protein ID: 778316193

Symbol: ARNT_HUMAN

Name: Class E basic helix-loop-helix protein 2

UniProtKB Accession Codes:

P27540 B2R9H1 C4AMA1 F8WAP6 Q59ED4 Q5QP39 Q8NDC7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 16 EPD 1 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 33 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MoonDB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 40 PDBsum 32 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 7 RefSeq 6 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1852076

Title: Cloning of a factor required for activity of the Ah (dioxin) receptor.

PubMed ID: 1852076

DOI: 10.1126/science.1852076

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 7539918

Title: Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

PubMed ID: 7539918

DOI: 10.1073/pnas.92.12.5510

PubMed ID: 1317062

Title: Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.

PubMed ID: 1317062

DOI: 10.1126/science.256.5060.1193

PubMed ID: 8621524

Title: Functional characterization of DNA-binding domains of the subunits of the heterodimeric aryl hydrocarbon receptor complex imputing novel and canonical basic helix-loop-helix protein-DNA interactions.

PubMed ID: 8621524

DOI: 10.1074/jbc.271.15.8843

PubMed ID: 10395741

Title: Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex.

PubMed ID: 10395741

DOI: 10.1006/abbi.1999.1282

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20699359

Title: Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.

PubMed ID: 20699359

DOI: 10.1242/jcs.068122

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28904176

Title: The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription.

PubMed ID: 28904176

DOI: 10.1074/jbc.m117.812974

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 34521881

Title: The role of DNA-binding and ARNT dimerization on the nucleo-cytoplasmic translocation of the aryl hydrocarbon receptor.

PubMed ID: 34521881

DOI: 10.1038/s41598-021-97507-w

PubMed ID: 16181639

Title: Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.

PubMed ID: 16181639

DOI: 10.1016/j.jmb.2005.08.043

PubMed ID: 19196990

Title: ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.

PubMed ID: 19196990

DOI: 10.1073/pnas.0808270106

PubMed ID: 28396409

Title: Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex.

PubMed ID: 28396409

DOI: 10.1073/pnas.1617035114

Sequence Information:

  • Length: 789
  • Mass: 86636
  • Checksum: 2E278F8E62BFBF6D
  • Sequence:
    • MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS 
ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS 
CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK 
TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE 
PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNVCQP 
TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG 
QVLSVMFRFR SKNQEWLWMR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPTLSNTIQ 
RPQLGPTANL PLEMGSGQLA PRQQQQQTEL DMVPGRDGLA SYNHSQVVQP VTTTGPEHSK 
PLEKSDGLFA QDRDPRFSEI YHNINADQSK GISSSTVPAT QQLFSQGNTF PPTPRPAENF 
RNSGLAPPVT IVQPSASAGQ MLAQISRHSN PTQGATPTWT PTTRSGFSAQ QVATQATAKT 
RTSQFGVGSF QTPSSFSSMS LPGAPTASPG AAAYPSLTNR GSNFAPETGQ TAGQFQTRTA 
EGVGVWPQWQ GQQPHHRSSS SEQHVQQPPA QQPGQPEVFQ EMLSMLGDQS NSYNNEEFPD 
LTMFPPFSE

Genular Protein ID: 654816128

Symbol: B0AZM1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0AZM1

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 2 Genevisible 1 GenomeRNAi 1 IntAct 1 InterPro 7 MINT 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 774
  • Mass: 84994
  • Checksum: 7DB22949B18F149C
  • Sequence:
    • MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERYARENHS EIERRRRNKM TAYITELSDM VPTCSALARK PDKLTILRMA 
VSHMKSLRGT GNTSTDGSYK PSFLTDQELK HLILEATDGF LFIVSCETGR VVYVSDSVTP 
VLNQPQSEWF GSTLYDQVHP DDVDKLREQL STSENALTGR ILDLKTGTVK KEGQQSSMRM 
CMGSRRSFIC RMRCGSSSVD PVSVNRLSFV RNRCRNGLGS VKDGEPHFVV VHCTGYIKAW 
PPAGVSLPDD DPEAGQGSKF CLVAIGRLQV TSSPNCTDMS NVCQPTEFIS RHNIEGIFTF 
VDHRCVATVG YQPQELLGKN IVEFCHPEDQ QLLRDSFQQV VKLKGQVLSV MFRFRSKNQE 
WLWMRTSSFT FQNPYSDEIE YIICTNTNVK NSSQEPRPTL SNTIQRPQLG PTANLPLEMG 
SGQLAPRQQQ QQTELDMVPG RDGLASYNHS QVVQPVTTTG PEHSKPLEKS DGLFAQDRDP 
RFSEIYHNIN ADQSKGISSS TVPATQQLFS QGNTFPPTPR PAENFRNSGL APPVTIVQPS 
ASAGQMLAQI SRHSNPTQGA TPTWTPTTRS GFSAQQVATQ ATAKTRTSQF GVGSFQTPSS 
FSSMSLPGAP TASPGAAAYP SLTNRGSNFA PETGQTAGQF QTRTAEGVGV WPQWQGQQPH 
HRSSSSEQHV QQPPAQQPGQ PEVFQEMLSM LGDQSNSYNN EEFPDLTMFP PFSE

Genular Protein ID: 3544862680

Symbol: Q53F30_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53F30

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 2 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 315
  • Mass: 34822
  • Checksum: 40F79278697E6EB8
  • Sequence:
    • MAATTANPEM TSDVPSLVPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS 
ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS 
CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK 
TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE 
PHFVVVHCTG YIKAW

Genular Protein ID: 4251561359

Symbol: A8K6P0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K6P0

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 EMBL 2 GO 6 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 773
  • Mass: 84721
  • Checksum: 37743C0A0AD918FA
  • Sequence:
    • MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERFARENHS EIERRRRNKM TAYITELSDM VPTCSALARK PDKLTILRMA 
VSHMKSLRGT GNTSTDGSYK PSFLTDQELK HLILEAADGF LFIVSCETGR VVYVSDSVTP 
VLNQPQSEWF GSTLYDQVHP DDVDKLREQL STSENALTGR ILDLKTGTVK KEGQQSSMRM 
CMGSRRSFIC RMRCGSSSVD PVSVNRLSFV RNRCRNGLGS VKDGEPHFVV VHCTGYIKAW 
PPAGVSLPDD DPEAGQGSKF CLVAIGRLQV TSSPNCTDMS NVCQPTEFIS RHNIEGIFTF 
VDHRCVATVG YQPQELLGKN IVEFCHPEDQ QLLRDSFQQV VKLKGQVLSV MFRFRSKNQE 
WLWMRTSSFT FQNPYSDEIE YIICTNTNVK NSSQEPRPTL SNTIQRPQLG PTANLPLEMG 
SGQLAPGQQQ QQTELDMVPG RDGLASYNHS QVVQPVTTTG PEHSKPLEKS DGLFAQDRDP 
RFSEIYHNIN ADQSKGISSS TVPATQQLFS QGNTFPPTPR PAENFRNSGL APPVTIVQPS 
ASAGQMLAQI SRHSNPTQGA TPTWTPTTRS GFSAQVATQA TAKTRTSQFG VGSFQTPSSF 
SSMSLPGAPT ASPGAAAYPS LTNRGSNFAP ETGQTAGQFQ TRTAEGVGVW PQWQGQQPHH 
RSSSSEQHVQ QPPAQQPGQP EVFQEMLSML GDQSNSYNNE EFPDLTMFPP FSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.