Details for: ARNT

Gene ID: 405

Symbol: ARNT

Ensembl ID: ENSG00000143437

Description: aryl hydrocarbon receptor nuclear translocator

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 209.5211
    Cell Significance Index: -32.5900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 132.9031
    Cell Significance Index: -33.7100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.0607
    Cell Significance Index: -35.9100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 70.6572
    Cell Significance Index: -28.7100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 64.2126
    Cell Significance Index: -33.0300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 30.1233
    Cell Significance Index: -28.7600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.3141
    Cell Significance Index: -34.9100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.6024
    Cell Significance Index: -33.7600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.7283
    Cell Significance Index: -29.8800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.1475
    Cell Significance Index: -20.0200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.9609
    Cell Significance Index: -35.3600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 2.7297
    Cell Significance Index: 519.4700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.6379
    Cell Significance Index: 26.9900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.5566
    Cell Significance Index: 30.3800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5478
    Cell Significance Index: 310.4800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.3585
    Cell Significance Index: 36.2800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3261
    Cell Significance Index: 263.1700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1568
    Cell Significance Index: 114.4300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0477
    Cell Significance Index: 946.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9407
    Cell Significance Index: 337.4000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9092
    Cell Significance Index: 23.3700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7363
    Cell Significance Index: 56.5100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.6964
    Cell Significance Index: 14.8900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6635
    Cell Significance Index: 107.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6539
    Cell Significance Index: 40.1900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6349
    Cell Significance Index: 69.0600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5724
    Cell Significance Index: 395.8600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5247
    Cell Significance Index: 31.5000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5102
    Cell Significance Index: 28.6300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4722
    Cell Significance Index: 29.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4328
    Cell Significance Index: 78.0200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.3507
    Cell Significance Index: 8.4100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3296
    Cell Significance Index: 45.2700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.2953
    Cell Significance Index: 4.2400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2914
    Cell Significance Index: 20.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2384
    Cell Significance Index: 448.9500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2351
    Cell Significance Index: 3.9600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2062
    Cell Significance Index: 5.9400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1927
    Cell Significance Index: 87.4400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1892
    Cell Significance Index: 12.7200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1861
    Cell Significance Index: 82.2600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1678
    Cell Significance Index: 2.0000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1620
    Cell Significance Index: 19.9200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1483
    Cell Significance Index: 6.7200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1428
    Cell Significance Index: 2.3900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1222
    Cell Significance Index: 77.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1007
    Cell Significance Index: 55.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0968
    Cell Significance Index: 149.0100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0963
    Cell Significance Index: 0.7900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0770
    Cell Significance Index: 1.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0765
    Cell Significance Index: 141.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0528
    Cell Significance Index: 71.7900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0162
    Cell Significance Index: 0.4400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0131
    Cell Significance Index: 0.4600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0126
    Cell Significance Index: 0.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0045
    Cell Significance Index: 0.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0040
    Cell Significance Index: -0.5100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0073
    Cell Significance Index: -0.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0316
    Cell Significance Index: -23.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0332
    Cell Significance Index: -5.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0350
    Cell Significance Index: -25.9200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0362
    Cell Significance Index: -1.6000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0372
    Cell Significance Index: -28.1800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0544
    Cell Significance Index: -30.6600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0618
    Cell Significance Index: -38.5900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0642
    Cell Significance Index: -7.5700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0749
    Cell Significance Index: -3.4900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0959
    Cell Significance Index: -13.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1011
    Cell Significance Index: -10.3300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1041
    Cell Significance Index: -29.9500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1135
    Cell Significance Index: -5.9000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1170
    Cell Significance Index: -3.2700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1506
    Cell Significance Index: -17.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1685
    Cell Significance Index: -17.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1715
    Cell Significance Index: -11.0700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1717
    Cell Significance Index: -8.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1743
    Cell Significance Index: -36.7100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1910
    Cell Significance Index: -22.2600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2028
    Cell Significance Index: -26.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2172
    Cell Significance Index: -4.6300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2226
    Cell Significance Index: -15.7400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2865
    Cell Significance Index: -21.3500
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2962
    Cell Significance Index: -4.2600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3081
    Cell Significance Index: -16.0500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3104
    Cell Significance Index: -14.5900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3425
    Cell Significance Index: -17.9800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3652
    Cell Significance Index: -5.3900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3768
    Cell Significance Index: -29.8400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3854
    Cell Significance Index: -5.6900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4111
    Cell Significance Index: -10.8100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4140
    Cell Significance Index: -25.3800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4580
    Cell Significance Index: -14.6700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5077
    Cell Significance Index: -12.6900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5096
    Cell Significance Index: -13.8700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5148
    Cell Significance Index: -6.4200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.5377
    Cell Significance Index: -13.1200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5519
    Cell Significance Index: -7.5300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.6544
    Cell Significance Index: -19.2200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6613
    Cell Significance Index: -14.4800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6627
    Cell Significance Index: -23.0300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Basic Helix-Loop-Helix (bHLH) Domain**: ARNT contains a bHLH domain, which is characteristic of basic helix-loop-helix transcription factors. This domain is essential for dimerization with AhR and subsequent DNA binding. 2. **Aryl Hydrocarbon Receptor Binding**: ARNT forms a heterodimer with AhR, enabling the receptor to bind to specific DNA sequences, known as dioxin response elements (DREs). 3. **Heterodimerization with AhR**: ARNT's ability to form a heterodimer with AhR is crucial for the regulation of gene expression in response to ligands. 4. **Cellular Expression**: ARNT is highly expressed in various cell types, including neurons, pigmented epithelial cells, and muscle cells. **Pathways and Functions** 1. **Aryl Hydrocarbon Receptor Signaling**: ARNT plays a central role in AhR signaling, facilitating the binding of AhR to DNA and modulating gene expression in response to ligands. 2. **Cell Differentiation**: ARNT is involved in regulating cell differentiation, particularly in the development of neurons and muscle cells. 3. **Metabolism**: ARNT modulates metabolic pathways, including lipid metabolism, by regulating the expression of genes involved in these processes. 4. **Response to Hypoxia**: ARNT is involved in the regulation of cellular responses to hypoxia, including the expression of genes involved in angiogenesis and energy metabolism. 5. **Regulation of Gene Expression**: ARNT regulates gene expression by interacting with transcription factors, such as HIF-1α, and modulating the expression of target genes. **Clinical Significance** 1. **Cancer**: Dysregulation of ARNT has been implicated in various cancers, including lung, breast, and colon cancer, where it can contribute to tumorigenesis and metastasis. 2. **Neurological Disorders**: ARNT has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it may contribute to the regulation of gene expression and cellular responses to stress. 3. **Metabolic Disorders**: ARNT's role in lipid metabolism and energy homeostasis makes it a potential target for the treatment of metabolic disorders, such as obesity and type 2 diabetes. 4. **Toxicology**: ARNT's role in xenobiotic metabolism and response to toxins makes it a potential biomarker for exposure to environmental toxins. In conclusion, ARNT plays a critical role in regulating various cellular processes, including cell differentiation, metabolism, and response to hypoxia. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of ARNT and its potential as a therapeutic target.

Genular Protein ID: 778316193

Symbol: ARNT_HUMAN

Name: Class E basic helix-loop-helix protein 2

UniProtKB Accession Codes:

P27540 B2R9H1 C4AMA1 F8WAP6 Q59ED4 Q5QP39 Q8NDC7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 16 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 33 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 33 PDBsum 33 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 7 RefSeq 6 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1852076

Title: Cloning of a factor required for activity of the Ah (dioxin) receptor.

PubMed ID: 1852076

DOI: 10.1126/science.1852076

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 7539918

Title: Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

PubMed ID: 7539918

DOI: 10.1073/pnas.92.12.5510

PubMed ID: 1317062

Title: Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor.

PubMed ID: 1317062

DOI: 10.1126/science.256.5060.1193

PubMed ID: 8621524

Title: Functional characterization of DNA-binding domains of the subunits of the heterodimeric aryl hydrocarbon receptor complex imputing novel and canonical basic helix-loop-helix protein-DNA interactions.

PubMed ID: 8621524

DOI: 10.1074/jbc.271.15.8843

PubMed ID: 10395741

Title: Interactions of nuclear receptor coactivator/corepressor proteins with the aryl hydrocarbon receptor complex.

PubMed ID: 10395741

DOI: 10.1006/abbi.1999.1282

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20699359

Title: Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.

PubMed ID: 20699359

DOI: 10.1242/jcs.068122

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28904176

Title: The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription.

PubMed ID: 28904176

DOI: 10.1074/jbc.m117.812974

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 34521881

Title: The role of DNA-binding and ARNT dimerization on the nucleo-cytoplasmic translocation of the aryl hydrocarbon receptor.

PubMed ID: 34521881

DOI: 10.1038/s41598-021-97507-w

PubMed ID: 16181639

Title: Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.

PubMed ID: 16181639

DOI: 10.1016/j.jmb.2005.08.043

PubMed ID: 19196990

Title: ARNT PAS-B has a fragile native state structure with an alternative beta-sheet register nearby in sequence space.

PubMed ID: 19196990

DOI: 10.1073/pnas.0808270106

PubMed ID: 28396409

Title: Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex.

PubMed ID: 28396409

DOI: 10.1073/pnas.1617035114

Sequence Information:

  • Length: 789
  • Mass: 86636
  • Checksum: 2E278F8E62BFBF6D
  • Sequence:
    • MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS 
ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS 
CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK 
TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE 
PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNVCQP 
TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG 
QVLSVMFRFR SKNQEWLWMR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPTLSNTIQ 
RPQLGPTANL PLEMGSGQLA PRQQQQQTEL DMVPGRDGLA SYNHSQVVQP VTTTGPEHSK 
PLEKSDGLFA QDRDPRFSEI YHNINADQSK GISSSTVPAT QQLFSQGNTF PPTPRPAENF 
RNSGLAPPVT IVQPSASAGQ MLAQISRHSN PTQGATPTWT PTTRSGFSAQ QVATQATAKT 
RTSQFGVGSF QTPSSFSSMS LPGAPTASPG AAAYPSLTNR GSNFAPETGQ TAGQFQTRTA 
EGVGVWPQWQ GQQPHHRSSS SEQHVQQPPA QQPGQPEVFQ EMLSMLGDQS NSYNNEEFPD 
LTMFPPFSE

Genular Protein ID: 4251561359

Symbol: A8K6P0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K6P0

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 8 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 773
  • Mass: 84721
  • Checksum: 37743C0A0AD918FA
  • Sequence:
    • MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERFARENHS EIERRRRNKM TAYITELSDM VPTCSALARK PDKLTILRMA 
VSHMKSLRGT GNTSTDGSYK PSFLTDQELK HLILEAADGF LFIVSCETGR VVYVSDSVTP 
VLNQPQSEWF GSTLYDQVHP DDVDKLREQL STSENALTGR ILDLKTGTVK KEGQQSSMRM 
CMGSRRSFIC RMRCGSSSVD PVSVNRLSFV RNRCRNGLGS VKDGEPHFVV VHCTGYIKAW 
PPAGVSLPDD DPEAGQGSKF CLVAIGRLQV TSSPNCTDMS NVCQPTEFIS RHNIEGIFTF 
VDHRCVATVG YQPQELLGKN IVEFCHPEDQ QLLRDSFQQV VKLKGQVLSV MFRFRSKNQE 
WLWMRTSSFT FQNPYSDEIE YIICTNTNVK NSSQEPRPTL SNTIQRPQLG PTANLPLEMG 
SGQLAPGQQQ QQTELDMVPG RDGLASYNHS QVVQPVTTTG PEHSKPLEKS DGLFAQDRDP 
RFSEIYHNIN ADQSKGISSS TVPATQQLFS QGNTFPPTPR PAENFRNSGL APPVTIVQPS 
ASAGQMLAQI SRHSNPTQGA TPTWTPTTRS GFSAQVATQA TAKTRTSQFG VGSFQTPSSF 
SSMSLPGAPT ASPGAAAYPS LTNRGSNFAP ETGQTAGQFQ TRTAEGVGVW PQWQGQQPHH 
RSSSSEQHVQ QPPAQQPGQP EVFQEMLSML GDQSNSYNNE EFPDLTMFPP FSE

Genular Protein ID: 3544862680

Symbol: Q53F30_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53F30

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 315
  • Mass: 34822
  • Checksum: 40F79278697E6EB8
  • Sequence:
    • MAATTANPEM TSDVPSLVPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS 
ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS 
CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK 
TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG SSSVDPVSVN RLSFVRNRCR NGLGSVKDGE 
PHFVVVHCTG YIKAW

Genular Protein ID: 654816128

Symbol: B0AZM1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B0AZM1

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 IntAct 1 InterPro 8 MINT 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 774
  • Mass: 84994
  • Checksum: 7DB22949B18F149C
  • Sequence:
    • MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL 
RCDDDQMSND KERYARENHS EIERRRRNKM TAYITELSDM VPTCSALARK PDKLTILRMA 
VSHMKSLRGT GNTSTDGSYK PSFLTDQELK HLILEATDGF LFIVSCETGR VVYVSDSVTP 
VLNQPQSEWF GSTLYDQVHP DDVDKLREQL STSENALTGR ILDLKTGTVK KEGQQSSMRM 
CMGSRRSFIC RMRCGSSSVD PVSVNRLSFV RNRCRNGLGS VKDGEPHFVV VHCTGYIKAW 
PPAGVSLPDD DPEAGQGSKF CLVAIGRLQV TSSPNCTDMS NVCQPTEFIS RHNIEGIFTF 
VDHRCVATVG YQPQELLGKN IVEFCHPEDQ QLLRDSFQQV VKLKGQVLSV MFRFRSKNQE 
WLWMRTSSFT FQNPYSDEIE YIICTNTNVK NSSQEPRPTL SNTIQRPQLG PTANLPLEMG 
SGQLAPRQQQ QQTELDMVPG RDGLASYNHS QVVQPVTTTG PEHSKPLEKS DGLFAQDRDP 
RFSEIYHNIN ADQSKGISSS TVPATQQLFS QGNTFPPTPR PAENFRNSGL APPVTIVQPS 
ASAGQMLAQI SRHSNPTQGA TPTWTPTTRS GFSAQQVATQ ATAKTRTSQF GVGSFQTPSS 
FSSMSLPGAP TASPGAAAYP SLTNRGSNFA PETGQTAGQF QTRTAEGVGV WPQWQGQQPH 
HRSSSSEQHV QQPPAQQPGQ PEVFQEMLSM LGDQSNSYNN EEFPDLTMFP PFSE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.