Details for: LTBP3

Gene ID: 4054

Symbol: LTBP3

Ensembl ID: ENSG00000168056

Description: latent transforming growth factor beta binding protein 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 229.3224
    Cell Significance Index: -35.6700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 136.2149
    Cell Significance Index: -34.5500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 88.3850
    Cell Significance Index: -36.4100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 72.9260
    Cell Significance Index: -34.4300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 70.4234
    Cell Significance Index: -28.6100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 64.2515
    Cell Significance Index: -33.0500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 30.0186
    Cell Significance Index: -28.6600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.5631
    Cell Significance Index: -36.4500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.5889
    Cell Significance Index: -31.0500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.5776
    Cell Significance Index: -23.1500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.9595
    Cell Significance Index: -30.5900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.2675
    Cell Significance Index: -36.5700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 3.4675
    Cell Significance Index: 47.3100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.5337
    Cell Significance Index: 40.6500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.5639
    Cell Significance Index: 44.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4986
    Cell Significance Index: 69.8700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.3224
    Cell Significance Index: 169.5200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1945
    Cell Significance Index: 1078.5500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1289
    Cell Significance Index: 224.0300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.0994
    Cell Significance Index: 29.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.0351
    Cell Significance Index: 142.1500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8817
    Cell Significance Index: 24.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.8769
    Cell Significance Index: 102.1900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7939
    Cell Significance Index: 86.3600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7306
    Cell Significance Index: 118.8200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7296
    Cell Significance Index: 322.5600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.6637
    Cell Significance Index: 10.5300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6305
    Cell Significance Index: 12.3100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5830
    Cell Significance Index: 41.2300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5051
    Cell Significance Index: 11.6700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4609
    Cell Significance Index: 13.2800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4568
    Cell Significance Index: 56.1700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4350
    Cell Significance Index: 237.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4036
    Cell Significance Index: 144.7700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3901
    Cell Significance Index: 38.5900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3563
    Cell Significance Index: 24.6400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3537
    Cell Significance Index: 63.7700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3365
    Cell Significance Index: 7.2900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3305
    Cell Significance Index: 14.9800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2619
    Cell Significance Index: 12.3100
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.2588
    Cell Significance Index: 2.1400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2581
    Cell Significance Index: 13.4100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2400
    Cell Significance Index: 165.9900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2306
    Cell Significance Index: 17.1900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2296
    Cell Significance Index: 11.9600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2047
    Cell Significance Index: 41.0700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1886
    Cell Significance Index: 35.9000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1247
    Cell Significance Index: 3.2800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1244
    Cell Significance Index: 8.0300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1084
    Cell Significance Index: 3.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0780
    Cell Significance Index: 146.8400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0415
    Cell Significance Index: 76.4600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0371
    Cell Significance Index: 57.0600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0341
    Cell Significance Index: 2.6200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0173
    Cell Significance Index: 10.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0147
    Cell Significance Index: 20.0400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0122
    Cell Significance Index: 1.5800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0118
    Cell Significance Index: 8.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0046
    Cell Significance Index: 0.7900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0008
    Cell Significance Index: -0.0500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0169
    Cell Significance Index: -7.6600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0264
    Cell Significance Index: -20.0100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0391
    Cell Significance Index: -4.6100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0444
    Cell Significance Index: -32.8900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0503
    Cell Significance Index: -5.1400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0613
    Cell Significance Index: -34.5900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0680
    Cell Significance Index: -42.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0762
    Cell Significance Index: -4.0000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0955
    Cell Significance Index: -27.4700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0989
    Cell Significance Index: -1.6600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1214
    Cell Significance Index: -6.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1328
    Cell Significance Index: -19.3100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1460
    Cell Significance Index: -3.1100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1688
    Cell Significance Index: -19.3400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1925
    Cell Significance Index: -40.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1991
    Cell Significance Index: -13.3900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2008
    Cell Significance Index: -8.8800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2020
    Cell Significance Index: -5.0500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2963
    Cell Significance Index: -11.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2974
    Cell Significance Index: -10.4500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3098
    Cell Significance Index: -32.2600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.3654
    Cell Significance Index: -4.6800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3663
    Cell Significance Index: -9.7800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3667
    Cell Significance Index: -29.0400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3884
    Cell Significance Index: -23.8100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.4258
    Cell Significance Index: -21.5200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4427
    Cell Significance Index: -27.9000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5230
    Cell Significance Index: -7.5100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5611
    Cell Significance Index: -17.9700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5817
    Cell Significance Index: -16.6000
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.5989
    Cell Significance Index: -5.0900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6547
    Cell Significance Index: -22.7500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6786
    Cell Significance Index: -7.0300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6816
    Cell Significance Index: -11.6800
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.6973
    Cell Significance Index: -7.2800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7204
    Cell Significance Index: -21.2200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.7410
    Cell Significance Index: -15.5100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.7429
    Cell Significance Index: -15.8800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.7599
    Cell Significance Index: -18.2300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7637
    Cell Significance Index: -19.5100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** LTBP3 is a secreted protein that belongs to the latent transforming growth factor beta-binding protein family. It is characterized by its ability to bind to latent TGF-β, preventing its activation and subsequent signaling. LTBP3 is expressed in various tissues, including bone, lung, and skin, and is highly conserved across species. Its expression is regulated by various transcription factors, including Smad3 and Smad4, which are key mediators of the TGF-β signaling pathway. **Pathways and Functions** LTBP3 is integral to the TGF-β signaling pathway, which plays a crucial role in regulating cell growth, differentiation, and survival. The TGF-β pathway is involved in various physiological processes, including bone mineralization, bone morphogenesis, and lung development. LTBP3 modulates the activity of TGF-β by binding to latent TGF-β, preventing its activation and subsequent signaling. This allows for precise regulation of TGF-β activity in different tissues and cell types. In addition to its role in the TGF-β signaling pathway, LTBP3 is also involved in other cellular processes, including collagen deposition, chondrocyte differentiation, and mesenchymal stem cell proliferation. Its expression is regulated by various transcription factors, including Smad3 and Smad4, which are key mediators of the TGF-β signaling pathway. **Clinical Significance** Dysregulation of LTBP3 has been implicated in various diseases, including bone disorders, such as osteoporosis and bone cancer. Overexpression of LTBP3 has been linked to increased bone mineralization and bone resorption, leading to bone loss and increased risk of osteoporosis. Conversely, underexpression of LTBP3 has been linked to impaired bone mineralization and bone morphogenesis, leading to bone defects and abnormalities. In the lung, LTBP3 plays a crucial role in lung development and function. Dysregulation of LTBP3 has been implicated in lung diseases, such as pulmonary fibrosis and lung cancer. Overexpression of LTBP3 has been linked to increased lung fibrosis and lung cancer, while underexpression of LTBP3 has been linked to impaired lung development and function. In summary, LTBP3 is a multifunctional protein that plays a crucial role in various physiological processes, including bone mineralization, bone morphogenesis, and lung development. Its dysregulation has been implicated in various diseases, including bone disorders and lung diseases. Further research is needed to fully understand the mechanisms of LTBP3 and its role in human disease. **Conclusion** In conclusion, LTBP3 is a key player in the TGF-β signaling pathway, which plays a crucial role in regulating cell growth, differentiation, and survival. Its dysregulation has been implicated in various diseases, including bone disorders and lung diseases. Further research is needed to fully understand the mechanisms of LTBP3 and its role in human disease.

Genular Protein ID: 2379055163

Symbol: LTBP3_HUMAN

Name: Latent-transforming growth factor beta-binding protein 3

UniProtKB Accession Codes:

Q9NS15 O15107 Q96HB9 Q9H7K2 Q9UFN4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 3 SMART 2 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12154076

Title: Secretion of human latent TGF-beta-binding protein-3 (LTBP-3) is dependent on co-expression of TGF-beta.

PubMed ID: 12154076

DOI: 10.1242/jcs.115.17.3457

PubMed ID: 9620332

Title: Analysis of the expression pattern of the latent transforming growth factor beta binding protein isoforms in normal and diseased human liver reveals a new splice variant missing the proteinase-sensitive hinge region.

PubMed ID: 9620332

DOI: 10.1002/hep.510270619

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10930463

Title: Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

PubMed ID: 10930463

DOI: 10.1091/mbc.11.8.2691

PubMed ID: 10743502

Title: Latent transforming growth factor-beta binding proteins (LTBPs) -- structural extracellular matrix proteins for targeting TGF-beta action.

PubMed ID: 10743502

DOI: 10.1016/s1359-6101(99)00010-6

PubMed ID: 11104663

Title: The latent transforming growth factor beta binding protein (LTBP) family.

PubMed ID: 11104663

DOI: 10.1042/bj3520601

PubMed ID: 16157329

Title: Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

PubMed ID: 16157329

DOI: 10.1016/j.yexcr.2005.08.008

PubMed ID: 27339457

Title: Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

PubMed ID: 27339457

DOI: 10.1016/j.matbio.2016.06.003

PubMed ID: 19344874

Title: Oligodontia is caused by mutation in LTBP3, the gene encoding latent TGF-beta binding protein 3.

PubMed ID: 19344874

DOI: 10.1016/j.ajhg.2009.03.007

PubMed ID: 27068007

Title: Mutations in LTBP3 cause acromicric dysplasia and geleophysic dysplasia.

PubMed ID: 27068007

DOI: 10.1136/jmedgenet-2015-103647

Sequence Information:

  • Length: 1303
  • Mass: 139359
  • Checksum: 3BC6B1EE19198414
  • Sequence:
    • MPGPRGAAGG LAPEMRGAGA AGLLALLLLL LLLLLGLGGR VEGGPAGERG AGGGGALARE 
RFKVVFAPVI CKRTCLKGQC RDSCQQGSNM TLIGENGHST DTLTGSGFRV VVCPLPCMNG 
GQCSSRNQCL CPPDFTGRFC QVPAGGAGGG TGGSGPGLSR TGALSTGALP PLAPEGDSVA 
SKHAIYAVQV IADPPGPGEG PPAQHAAFLV PLGPGQISAE VQAPPPVVNV RVHHPPEASV 
QVHRIESSNA ESAAPSQHLL PHPKPSHPRP PTQKPLGRCF QDTLPKQPCG SNPLPGLTKQ 
EDCCGSIGTA WGQSKCHKCP QLQYTGVQKP GPVRGEVGAD CPQGYKRLNS THCQDINECA 
MPGVCRHGDC LNNPGSYRCV CPPGHSLGPS RTQCIADKPE EKSLCFRLVS PEHQCQHPLT 
TRLTRQLCCC SVGKAWGARC QRCPTDGTAA FKEICPAGKG YHILTSHQTL TIQGESDFSL 
FLHPDGPPKP QQLPESPSQA PPPEDTEEER GVTTDSPVSE ERSVQQSHPT ATTTPARPYP 
ELISRPSPPT MRWFLPDLPP SRSAVEIAPT QVTETDECRL NQNICGHGEC VPGPPDYSCH 
CNPGYRSHPQ HRYCVDVNEC EAEPCGPGRG ICMNTGGSYN CHCNRGYRLH VGAGGRSCVD 
LNECAKPHLC GDGGFCINFP GHYKCNCYPG YRLKASRPPV CEDIDECRDP SSCPDGKCEN 
KPGSFKCIAC QPGYRSQGGG ACRDVNECAE GSPCSPGWCE NLPGSFRCTC AQGYAPAPDG 
RSCLDVDECE AGDVCDNGIC SNTPGSFQCQ CLSGYHLSRD RSHCEDIDEC DFPAACIGGD 
CINTNGSYRC LCPQGHRLVG GRKCQDIDEC SQDPSLCLPH GACKNLQGSY VCVCDEGFTP 
TQDQHGCEEV EQPHHKKECY LNFDDTVFCD SVLATNVTQQ ECCCSLGAGW GDHCEIYPCP 
VYSSAEFHSL CPDGKGYTQD NNIVNYGIPA HRDIDECMLF GSEICKEGKC VNTQPGYECY 
CKQGFYYDGN LLECVDVDEC LDESNCRNGV CENTRGGYRC ACTPPAEYSP AQRQCLSPEE 
MDVDECQDPA ACRPGRCVNL PGSYRCECRP PWVPGPSGRD CQLPESPAER APERRDVCWS 
QRGEDGMCAG PLAGPALTFD DCCCRQGRGW GAQCRPCPPR GAGSHCPTSQ SESNSFWDTS 
PLLLGKPPRD EDSSEEDSDE CRCVSGRCVP RPGGAVCECP GGFQLDASRA RCVDIDECRE 
LNQRGLLCKS ERCVNTSGSF RCVCKAGFAR SRPHGACVPQ RRR

Genular Protein ID: 1853100906

Symbol: B9EG76_HUMAN

Name: N/A

UniProtKB Accession Codes:

B9EG76

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 2 Gene3D 2 IntAct 1 InterPro 11 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 8 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 3

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1139
  • Mass: 122596
  • Checksum: 50EEDCB507224080
  • Sequence:
    • MNGGQCSSRN QCLCPPDFTG RFCQVPAGGA GGGTGGSGPG LSRTGALSTG ALPPLAPEGD 
SVASKHAIYA VQVIADPPGP GEGPPAQHAA FLVPLGPGQI SAEVQAPPPV VNVRVHHPPE 
ASVQVHRIES SNAESAAPSQ HLLPHPKPSH PRPPTQKPLG RCFQDTLPKQ PCGSNPLPGL 
TKQEDCCGSI GTAWGQSKCH KCPQLQYTGV QKPGPVRGEV GADCPQGYKR LNSTHCQDIN 
ECAMPGVCRH GDCLNNPGSY RCVCPPGHSL GPSRTQCIAD KPEEKSLCFR LVSPEHQCQH 
PLTTRLTRQL CCCSVGKAWG ARCQRCPTDG TAAFKEICPA GKGYHILTSH QTLTIQGESD 
FSLFLHPDGP PKPQQLPESP SQAPPPEDTE EERGVTTDSP VSEERSVQQS HPTATTTPAR 
PYPELISRPS PPTMRWFLPD LPPSRSAVEI APTQVTETDE CRLNQNICGH GECVPGPPDY 
SCHCNPGYRS HPQHRYCVDV NECEAEPCGP GRGICMNTGG SYNCHCNRGY RLHVGAGGRS 
CVDLNECAKP HLCGDGGFCI NFPGHYKCNC YPGYRLKASR PPVCEDIDEC RDPSSCPDGK 
CENKPGSFKC IACQPGYRSQ GGGACRDVNE CAEGSPCSPG WCENLPGSFR CTCAQGYAPA 
PDGRSCLDVD ECEAGDVCDN GICSNTPGSF QCQCLSGYHL SRDRSHCEDI DECDFPAACI 
GGDCINTNGS YRCLCPQGHR LVGGRKCQDI DECSQDPSLC LPHGACKNLQ GSYVCVCDEG 
FTPTQDQHGC EEVEQPHHKK ECYLNFDDTV FCDSVLATNV TQQECCCSLG AGWGDHCEIY 
PCPVYSSAEF HSLCPDGKGY TQDNNIVNYG IPAHRDIDEC MLFGSEICKE GKCVNTQPGY 
ECYCKQGFYY DGNLLECVDV DECLDESNCR NGVCENTRGG YRCACTPPAE YSPAQRQCLS 
PEEMERAPER RDVCWSQRGE DGMCAGPLAG PALTFDDCCC RQGRGWGAQC RPCPPRGAGS 
HCPTSQSESN SFWDTSPLLL GKPPRDEDSS EEDSDECRCV SGRCVPRPGG AVCECPGGFQ 
LDASRARCVD IDECRELNQR GLLCKSERCV NTSGSFRCVC KAGFARSRPH GACVPQRRR

Genular Protein ID: 2236646199

Symbol: Q8WYU6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8WYU6

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 8 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 3 SAM 1 SMART 2 SUPFAM 3

Sequence Information:

  • Length: 263
  • Mass: 28251
  • Checksum: 636CFA1C2AEC701D
  • Sequence:
    • MLFGSEICKE GKCVNTQPGY ECYCKQGFYY DGNLLECVDV DECLDESNCR NGVCENTRGG 
YRCACTPPAE YSPAQRQSLS PEEMDVDECQ DPAACRPGRC VNLPGSYRCE CRPPWVPGPS 
GRDCQLPESP AERAPERRDV CWSQRGEDGM CAGPLAGPAL TFDDCCCRQG RGWGAQCRPC 
PPRGAGSHCP TSQSESNSFW DTSPLLLGKP PRDEDSSEED SDECRCVSAA ACRGRAAPCA 
SVPAASSSTP PAPAAWISTS AES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.