Details for: LY9
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 23.9707
Cell Significance Index: -6.0800 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 19.8656
Cell Significance Index: -3.0900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 14.1065
Cell Significance Index: -6.6600 - Cell Name: centroblast (CL0009112)
Fold Change: 7.0122
Cell Significance Index: 16.3600 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 3.9578
Cell Significance Index: 10.6000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 3.4568
Cell Significance Index: 74.8900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 2.9604
Cell Significance Index: -3.6500 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 1.5628
Cell Significance Index: -4.8000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 1.5560
Cell Significance Index: -6.1400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.4085
Cell Significance Index: 166.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.9654
Cell Significance Index: 183.7300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.9482
Cell Significance Index: 42.9800 - Cell Name: T-helper 22 cell (CL0001042)
Fold Change: 0.6497
Cell Significance Index: 1.9800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.6393
Cell Significance Index: 13.6200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5856
Cell Significance Index: 35.1600 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 0.5400
Cell Significance Index: 2.4200 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.4358
Cell Significance Index: 4.3700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4218
Cell Significance Index: 45.8800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4000
Cell Significance Index: 39.5700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3464
Cell Significance Index: 312.7800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.2797
Cell Significance Index: 18.0500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2474
Cell Significance Index: 40.2400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2184
Cell Significance Index: 15.1100 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.1589
Cell Significance Index: 0.4900 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: 0.0673
Cell Significance Index: 1.1600 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: 0.0569
Cell Significance Index: 0.5900 - Cell Name: follicular B cell (CL0000843)
Fold Change: 0.0540
Cell Significance Index: 0.2700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0009
Cell Significance Index: 0.0300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0000
Cell Significance Index: 0.0100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0003
Cell Significance Index: -0.0200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0024
Cell Significance Index: -0.0700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0026
Cell Significance Index: -4.8700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0028
Cell Significance Index: -0.0700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0029
Cell Significance Index: -5.3500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0036
Cell Significance Index: -5.5600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0037
Cell Significance Index: -0.1000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0038
Cell Significance Index: -5.1300 - Cell Name: mature T cell (CL0002419)
Fold Change: -0.0069
Cell Significance Index: -0.0500 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.0073
Cell Significance Index: -0.0400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0074
Cell Significance Index: -5.5800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0084
Cell Significance Index: -6.2200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0103
Cell Significance Index: -2.0500 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0112
Cell Significance Index: -6.1300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0114
Cell Significance Index: -6.4400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0116
Cell Significance Index: -0.2400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0128
Cell Significance Index: -9.4000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0144
Cell Significance Index: -9.1400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0158
Cell Significance Index: -5.6800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0168
Cell Significance Index: -7.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0189
Cell Significance Index: -3.7900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0206
Cell Significance Index: -0.3100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0281
Cell Significance Index: -8.0900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0289
Cell Significance Index: -3.7100 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0292
Cell Significance Index: -1.2700 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.0304
Cell Significance Index: -0.4500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0309
Cell Significance Index: -6.5100 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: -0.0315
Cell Significance Index: -0.1900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0323
Cell Significance Index: -5.5100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0364
Cell Significance Index: -1.1700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0394
Cell Significance Index: -4.5900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0401
Cell Significance Index: -7.2400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0431
Cell Significance Index: -1.1000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0445
Cell Significance Index: -6.1100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0447
Cell Significance Index: -2.2600 - Cell Name: leukocyte (CL0000738)
Fold Change: -0.0500
Cell Significance Index: -0.8500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0533
Cell Significance Index: -6.1100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0584
Cell Significance Index: -8.4900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0586
Cell Significance Index: -7.2100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0590
Cell Significance Index: -6.1400 - Cell Name: lymphocyte (CL0000542)
Fold Change: -0.0647
Cell Significance Index: -0.8800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0662
Cell Significance Index: -8.5500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0781
Cell Significance Index: -7.9800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0809
Cell Significance Index: -3.3100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0860
Cell Significance Index: -4.0400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0884
Cell Significance Index: -6.7800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0899
Cell Significance Index: -2.6400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0968
Cell Significance Index: -6.5100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1100
Cell Significance Index: -5.1300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1155
Cell Significance Index: -8.6100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1178
Cell Significance Index: -6.6100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1186
Cell Significance Index: -6.1600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1204
Cell Significance Index: -6.3200 - Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
Fold Change: -0.1207
Cell Significance Index: -1.1600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1253
Cell Significance Index: -7.7000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1334
Cell Significance Index: -5.9000 - Cell Name: memory B cell (CL0000787)
Fold Change: -0.1344
Cell Significance Index: -1.4300 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: -0.1360
Cell Significance Index: -1.4100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1417
Cell Significance Index: -3.9600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1531
Cell Significance Index: -5.6200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1581
Cell Significance Index: -5.9900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.1607
Cell Significance Index: -5.6300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1730
Cell Significance Index: -5.5100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1738
Cell Significance Index: -5.6900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1879
Cell Significance Index: -4.8300 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1894
Cell Significance Index: -5.9900 - Cell Name: naive B cell (CL0000788)
Fold Change: -0.1947
Cell Significance Index: -2.0500 - Cell Name: B-1b B cell (CL0000821)
Fold Change: -0.1974
Cell Significance Index: -0.9900 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2017
Cell Significance Index: -5.4900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2029
Cell Significance Index: -2.9100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2079
Cell Significance Index: -5.5500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3637231047
Symbol: LY9_HUMAN
Name: T-lymphocyte surface antigen Ly-9
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10970093
Title: Gene structure of the mouse leukocyte cell surface molecule Ly9.
PubMed ID: 10970093
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8537117
Title: Isolation and characterization of cDNA clones for Humly9: the human homologue of mouse Ly9.
PubMed ID: 8537117
DOI: 10.1007/bf00186599
PubMed ID: 11389028
Title: Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP.
PubMed ID: 11389028
PubMed ID: 12458214
Title: Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors.
PubMed ID: 12458214
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 22989874
Title: CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances RORgammat recruitment to the IL17A promoter in human T lymphocytes.
PubMed ID: 22989874
PubMed ID: 22184727
Title: Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation.
PubMed ID: 22184727
PubMed ID: 26221972
Title: A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activation.
PubMed ID: 26221972
DOI: 10.1111/imm.12513
Sequence Information:
- Length: 655
- Mass: 72139
- Checksum: 84ABA3056D69E80A
- Sequence:
MVAPKSHTDD WAPGPFSSKP QRSQLQIFSS VLQTSLLFLL MGLRASGKDS APTVVSGILG GSVTLPLNIS VDTEIENVIW IGPKNALAFA RPKENVTIMV KSYLGRLDIT KWSYSLCISN LTLNDAGSYK AQINQRNFEV TTEEEFTLFV YEQLQEPQVT MKSVKVSENF SCNITLMCSV KGAEKSVLYS WTPREPHASE SNGGSILTVS RTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRRL RKPKITWSLR HSEDGICRIS LTCSVEDGGN TVMYTWTPLQ KEAVVSQGES HLNVSWRSSE NHPNLTCTAS NPVSRSSHQF LSENICSGPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN TMYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVPPPQQ NDLEIPESPT YENFT
Genular Protein ID: 1185610984
Symbol: A0A0C4DFU4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 193
- Mass: 21169
- Checksum: D9552BB4293C5B00
- Sequence:
MVAPKSHTDD WAPGPFSSKP QRSQLQIFSS VLQTSLLFLL MGLRASGKDS APTVVSGILG GSVTLPLNIS VDTEIENVIW IGPKNALAFA RPKENVTIMV KSYLGRLDIT KWSYSLCISN LTLNDAGSYK AQINQRNFEV TTEEEFTLFV YAPFIEKLSV HVIEGDHRTL LEGSGLESII STLAEPRVSV REG
Genular Protein ID: 2075334458
Symbol: Q0VAI0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 405
- Mass: 44303
- Checksum: 7328727CBABCE8F6
- Sequence:
MKSVKVSENF SCNITLMCSV KGAEKSVLYS WTPREPHASE SNGGSILTVS GTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN TVYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVPPPQQ NDLEIPESPT YENFT
Genular Protein ID: 1531412087
Symbol: Q5VYH9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 565
- Mass: 62113
- Checksum: 833D30A2797B2EBF
- Sequence:
MVAPKSHTDD WAPGPFSSKP QRSQLQIFSS VLQTSLLFLL MGLRASGKDS APTVVSGILG GSVTLPLNIS VDTEIENVIW IGPKNALAFA RPKENVTIMV KSYLGRLDIT KWSYSLCISN LTLNDAGSYK AQINQRNFEV TTEEEFTLFV YEQLQEPQVT MKSVKVSENF SCNITLMCSV KGAEKSVLYS WTPREPHASE SNGGSILTVS RTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN TMYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVPPPQQ NDLEIPESPT YENFT
Genular Protein ID: 3804815413
Symbol: Q05CA2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 405
- Mass: 44402
- Checksum: D739607D6CB18F21
- Sequence:
MKSVKVSENF SCNITLMCSV KGAEKSVLYS WTPREPHASE SNGGSILTVS RTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN TVYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVPPPQQ NDLEIPESPT YENFT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.