Details for: MFAP1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 174.6116
Cell Significance Index: -27.1600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 109.5633
Cell Significance Index: -27.7900 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 72.4364
Cell Significance Index: -29.8400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 69.0499
Cell Significance Index: -32.6000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 64.6389
Cell Significance Index: -26.2600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 27.6305
Cell Significance Index: -26.3800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 25.2077
Cell Significance Index: -31.0800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.9296
Cell Significance Index: -26.6000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.0992
Cell Significance Index: -31.9600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.2474
Cell Significance Index: -22.2600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.7186
Cell Significance Index: 46.7800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.5553
Cell Significance Index: 93.3700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.4237
Cell Significance Index: 38.0200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.3665
Cell Significance Index: 148.6300 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 1.3072
Cell Significance Index: 10.9800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.1109
Cell Significance Index: 136.6000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.0789
Cell Significance Index: 68.0000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 1.0103
Cell Significance Index: 182.1200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.8016
Cell Significance Index: 41.6400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.7896
Cell Significance Index: 27.4400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.7372
Cell Significance Index: 402.6100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.7118
Cell Significance Index: 49.2300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.6922
Cell Significance Index: 95.0600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5698
Cell Significance Index: 251.9100 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.5185
Cell Significance Index: 4.1400 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5150
Cell Significance Index: 10.7800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5059
Cell Significance Index: 22.9300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.4995
Cell Significance Index: 4.6000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4736
Cell Significance Index: 55.8500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4267
Cell Significance Index: 69.4100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4226
Cell Significance Index: 19.8600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.4175
Cell Significance Index: 83.7500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.4040
Cell Significance Index: 10.1000 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.3743
Cell Significance Index: 2.8900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.3613
Cell Significance Index: 71.7100 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.3518
Cell Significance Index: 9.2500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.3176
Cell Significance Index: 22.4600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3161
Cell Significance Index: 40.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.3037
Cell Significance Index: 14.1600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2690
Cell Significance Index: 7.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.2390
Cell Significance Index: 17.8200 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.1748
Cell Significance Index: 1.9000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1707
Cell Significance Index: 8.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1650
Cell Significance Index: 59.1900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1226
Cell Significance Index: 84.8200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1133
Cell Significance Index: 11.2100 - Cell Name: peg cell (CL4033014)
Fold Change: 0.1091
Cell Significance Index: 2.5200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.1056
Cell Significance Index: 1.2000 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0802
Cell Significance Index: 10.3600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0753
Cell Significance Index: 3.9200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0425
Cell Significance Index: 0.9200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0379
Cell Significance Index: 2.4500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0182
Cell Significance Index: 0.6400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0119
Cell Significance Index: 8.7400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0044
Cell Significance Index: 0.8400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0007
Cell Significance Index: 1.3800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0063
Cell Significance Index: -8.5600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0065
Cell Significance Index: -9.9300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0115
Cell Significance Index: -21.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0153
Cell Significance Index: -0.8600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0156
Cell Significance Index: -11.8000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0214
Cell Significance Index: -13.6200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0235
Cell Significance Index: -0.2800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0371
Cell Significance Index: -27.5000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0385
Cell Significance Index: -17.4800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0467
Cell Significance Index: -4.7700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0525
Cell Significance Index: -29.6000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0562
Cell Significance Index: -0.9400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0581
Cell Significance Index: -36.3000 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: -0.0621
Cell Significance Index: -0.6600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0662
Cell Significance Index: -0.5400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0675
Cell Significance Index: -5.1800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0853
Cell Significance Index: -24.5500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0900
Cell Significance Index: -13.0800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0996
Cell Significance Index: -17.0000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1004
Cell Significance Index: -11.7000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1209
Cell Significance Index: -3.5500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1209
Cell Significance Index: -3.2400 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1374
Cell Significance Index: -0.8300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1570
Cell Significance Index: -17.9900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1580
Cell Significance Index: -3.3700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1669
Cell Significance Index: -2.8600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1725
Cell Significance Index: -36.3400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1777
Cell Significance Index: -1.8400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1796
Cell Significance Index: -2.4500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2192
Cell Significance Index: -6.1300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2329
Cell Significance Index: -5.9500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2622
Cell Significance Index: -20.7700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2827
Cell Significance Index: -19.0100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3003
Cell Significance Index: -4.5000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3012
Cell Significance Index: -31.3600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3303
Cell Significance Index: -20.3000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3567
Cell Significance Index: -10.2300 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.3686
Cell Significance Index: -4.7200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3766
Cell Significance Index: -9.6800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4026
Cell Significance Index: -12.9000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4379
Cell Significance Index: -19.3700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4389
Cell Significance Index: -26.9100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.5125
Cell Significance Index: -13.7100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.5321
Cell Significance Index: -20.1500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3722165805
Symbol: MFAP1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7835894
Title: Structure of the human gene encoding the associated microfibrillar protein (MFAP1) and localization to chromosome 15q15-q21.
PubMed ID: 7835894
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 26673105
Title: Multiple protein-protein interactions converging on the Prp38 protein during activation of the human spliceosome.
PubMed ID: 26673105
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 27773687
Title: Scaffolding in the Spliceosome via Single alpha Helices.
PubMed ID: 27773687
PubMed ID: 28781166
Title: Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
PubMed ID: 28781166
Sequence Information:
- Length: 439
- Mass: 51958
- Checksum: 0EF6F4F091C05A88
- Sequence:
MSVPSALMKQ PPIQSTAGAV PVRNEKGEIS MEKVKVKRYV SGKRPDYAPM ESSDEEDEEF QFIKKAKEQE AEPEEQEEDS SSDPRLRRLQ NRISEDVEER LARHRKIVEP EVVGESDSEV EGDAWRMERE DSSEEEEEEI DDEEIERRRG MMRQRAQERK NEEMEVMEVE DEGRSGEESE SESEYEEYTD SEDEMEPRLK PVFIRKKDRV TVQEREAEAL KQKELEQEAK RMAEERRKYT LKIVEEETKK ELEENKRSLA ALDALNTDDE NDEEEYEAWK VRELKRIKRD REDREALEKE KAEIERMRNL TEEERRAELR ANGKVITNKA VKGKYKFLQK YYHRGAFFMD EDEEVYKRDF SAPTLEDHFN KTILPKVMQV KNFGRSGRTK YTHLVDQDTT SFDSAWGQES AQNTKFFKQK AAGVRDVFER PSAKKRKTT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.