Details for: NQO2

Gene ID: 4835

Symbol: NQO2

Ensembl ID: ENSG00000124588

Description: N-ribosyldihydronicotinamide:quinone dehydrogenase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 219.2288
    Cell Significance Index: -34.1000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 138.3636
    Cell Significance Index: -35.1000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 79.4497
    Cell Significance Index: -37.5100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 76.5648
    Cell Significance Index: -31.1100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 69.7823
    Cell Significance Index: -35.9000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 32.6659
    Cell Significance Index: -31.1900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.1771
    Cell Significance Index: -38.4400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.7648
    Cell Significance Index: -34.2000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.5650
    Cell Significance Index: -32.4500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.0176
    Cell Significance Index: -39.5300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.4836
    Cell Significance Index: -14.1900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.9101
    Cell Significance Index: 30.6500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6574
    Cell Significance Index: 332.4700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.5292
    Cell Significance Index: 44.0600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.2320
    Cell Significance Index: 57.4400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1786
    Cell Significance Index: 16.0800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.9712
    Cell Significance Index: 50.9900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9393
    Cell Significance Index: 336.9100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7799
    Cell Significance Index: 35.3500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7764
    Cell Significance Index: 14.3500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7664
    Cell Significance Index: 692.0300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.7228
    Cell Significance Index: 8.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6568
    Cell Significance Index: 71.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5738
    Cell Significance Index: 15.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.5709
    Cell Significance Index: 73.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4765
    Cell Significance Index: 77.5100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4602
    Cell Significance Index: 9.9700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4561
    Cell Significance Index: 90.5200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4556
    Cell Significance Index: 34.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3409
    Cell Significance Index: 46.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3038
    Cell Significance Index: 21.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2706
    Cell Significance Index: 12.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2530
    Cell Significance Index: 138.1800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2406
    Cell Significance Index: 8.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2078
    Cell Significance Index: 37.4600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1864
    Cell Significance Index: 35.4700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1688
    Cell Significance Index: 4.3400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1544
    Cell Significance Index: 3.8600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1459
    Cell Significance Index: 64.5200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1400
    Cell Significance Index: 17.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1326
    Cell Significance Index: 17.1300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1210
    Cell Significance Index: 11.9700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1193
    Cell Significance Index: 7.3300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0964
    Cell Significance Index: 2.7000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0857
    Cell Significance Index: 54.4200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0789
    Cell Significance Index: 54.5500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0748
    Cell Significance Index: 140.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0554
    Cell Significance Index: 4.1300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0411
    Cell Significance Index: 1.8200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0308
    Cell Significance Index: 0.8800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0275
    Cell Significance Index: 1.8500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0155
    Cell Significance Index: 11.3700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0124
    Cell Significance Index: 19.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0108
    Cell Significance Index: 0.4100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0099
    Cell Significance Index: 0.1700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.0020
    Cell Significance Index: 0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0011
    Cell Significance Index: 1.9900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0139
    Cell Significance Index: -0.3700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0209
    Cell Significance Index: -2.1400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0230
    Cell Significance Index: -31.3400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0309
    Cell Significance Index: -5.2800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0321
    Cell Significance Index: -24.3300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0361
    Cell Significance Index: -16.3700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0380
    Cell Significance Index: -0.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0454
    Cell Significance Index: -33.6300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0587
    Cell Significance Index: -3.0500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0613
    Cell Significance Index: -34.5600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0720
    Cell Significance Index: -1.9600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0737
    Cell Significance Index: -46.0500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1021
    Cell Significance Index: -29.3700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1142
    Cell Significance Index: -16.6000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1219
    Cell Significance Index: -3.5800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1499
    Cell Significance Index: -17.6800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1584
    Cell Significance Index: -11.2000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1805
    Cell Significance Index: -21.0400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2029
    Cell Significance Index: -6.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2039
    Cell Significance Index: -42.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2090
    Cell Significance Index: -3.5000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2121
    Cell Significance Index: -24.3000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2158
    Cell Significance Index: -17.0900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2243
    Cell Significance Index: -14.1400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2285
    Cell Significance Index: -14.7400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2396
    Cell Significance Index: -12.4800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2669
    Cell Significance Index: -7.6500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2921
    Cell Significance Index: -6.2000
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.3087
    Cell Significance Index: -2.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3515
    Cell Significance Index: -36.6000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3792
    Cell Significance Index: -23.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3974
    Cell Significance Index: -22.3000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4043
    Cell Significance Index: -9.7000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4220
    Cell Significance Index: -10.7800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4282
    Cell Significance Index: -5.3400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4368
    Cell Significance Index: -15.1800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.4660
    Cell Significance Index: -7.8500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5484
    Cell Significance Index: -14.6700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5701
    Cell Significance Index: -14.9900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.5950
    Cell Significance Index: -7.5100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6135
    Cell Significance Index: -12.1300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6328
    Cell Significance Index: -14.6200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.6364
    Cell Significance Index: -12.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Electron Transport Chain**: NQO2 is a key player in the electron transport chain, where it facilitates the transfer of electrons from NAD(P)H to quinones, ultimately contributing to the generation of ATP. 2. **Antioxidant Function**: By reducing quinones, NQO2 helps to neutralize reactive oxygen species (ROS), thereby protecting cells from oxidative damage and stress. 3. **Dual Substrate Specificity**: NQO2 exhibits dual substrate specificity, accepting both NAD(P)H and dihydronicotinamide (NAD+), allowing it to participate in various metabolic pathways. 4. **Homodimerization**: NQO2 is known to form homodimers, which may facilitate its interaction with other proteins and enhance its enzymatic activity. **Pathways and Functions** 1. **Electron Transport Chain**: NQO2 is integral to the electron transport chain, where it helps to generate ATP by transferring electrons from NAD(P)H to quinones. 2. **Antioxidant Defense**: By reducing quinones, NQO2 protects cells from oxidative stress and damage caused by ROS. 3. **Metabolic Pathways**: NQO2 participates in various metabolic pathways, including energy metabolism, fatty acid oxidation, and cholesterol synthesis. 4. **Cell Signaling**: NQO2 may also interact with signaling molecules, modulating cellular responses to oxidative stress and other stimuli. **Clinical Significance** 1. **Cancer Therapy**: NQO2 has been identified as a potential target for cancer therapy, as it is overexpressed in certain types of cancer, including lung, breast, and colon cancer. 2. **Neurodegenerative Diseases**: NQO2 may play a role in the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's, where oxidative stress is a key contributor. 3. **Neuroprotection**: NQO2 may serve as a neuroprotective agent, protecting neurons from oxidative damage and stress. 4. **Metabolic Disorders**: NQO2 may also be involved in metabolic disorders, such as obesity and diabetes, where oxidative stress is a contributing factor. In conclusion, NQO2 is a multifunctional enzyme that plays a crucial role in maintaining cellular homeostasis by protecting cells from oxidative stress and participating in various metabolic pathways. Its dysregulation has been implicated in various diseases, highlighting the need for further research into its clinical significance and potential therapeutic applications.

Genular Protein ID: 3353390024

Symbol: NQO2_HUMAN

Name: Ribosyldihydronicotinamide dehydrogenase [quinone]

UniProtKB Accession Codes:

P16083 B2R492 Q5TD04

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 17 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 14 DrugCentral 1 EC 1 EMBL 8 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 68 PDBsum 68 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 1 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1691923

Title: Nucleotide and deduced amino acid sequence of a human cDNA (NQO2) corresponding to a second member of the NAD(P)H:quinone oxidoreductase gene family. Extensive polymorphism at the NQO2 gene locus on chromosome 6.

PubMed ID: 1691923

DOI: 10.1021/bi00459a034

PubMed ID: 8182056

Title: Human NAD(P)H:quinone oxidoreductase 2. Gene structure, activity, and tissue-specific expression.

PubMed ID: 8182056

DOI: 10.1016/s0021-9258(17)36651-6

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9367528

Title: Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.

PubMed ID: 9367528

DOI: 10.1006/abbi.1997.0344

PubMed ID: 9050836

Title: Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase).

PubMed ID: 9050836

DOI: 10.1073/pnas.94.5.1669

PubMed ID: 15078100

Title: Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines.

PubMed ID: 15078100

DOI: 10.1021/bi035923w

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 10433694

Title: Crystal structure of human quinone reductase type 2, a metalloflavoprotein.

PubMed ID: 10433694

DOI: 10.1021/bi990799v

PubMed ID: 15350128

Title: Crystal structure of quinone reductase 2 in complex with resveratrol.

PubMed ID: 15350128

DOI: 10.1021/bi049162o

PubMed ID: 16129418

Title: Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954.

PubMed ID: 16129418

DOI: 10.1016/j.bbrc.2005.08.081

PubMed ID: 18254726

Title: Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.

PubMed ID: 18254726

DOI: 10.1042/bj20071373

PubMed ID: 18579530

Title: Quinone reductase 2 is a catechol quinone reductase.

PubMed ID: 18579530

DOI: 10.1074/jbc.m801371200

PubMed ID: 19236722

Title: The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2).

PubMed ID: 19236722

DOI: 10.1186/1472-6807-9-7

Sequence Information:

  • Length: 231
  • Mass: 25919
  • Checksum: FE1F4D577517B972
  • Sequence:
    • MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNLEPR ATDKDITGTL 
SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QFPLYWFSVP AILKGWMDRV 
LCQGFAFDIP GFYDSGLLQG KLALLSVTTG GTAEMYTKTG VNGDSRYFLW PLQHGTLHFC 
GFKVLAPQIS FAPEIASEEE RKGMVAAWSQ RLQTIWKEEP IPCTAHWHFG Q

Genular Protein ID: 1254371009

Symbol: B3KPX6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KPX6

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 3 SMR 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 231
  • Mass: 25949
  • Checksum: FE1F4D5773A10972
  • Sequence:
    • MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNLEPR ATDKDITGTL 
SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QFPLYWFSVP AILKGWMDRV 
LCQGFAFDIP GFYDSGLLQG KLALLSVTTG GTAEMYTKTG VNGDSRYFLW PLQHGTLHFC 
GFKVLAPQIS FAPEIASEEE RKGMVAAWSQ WLQTIWKEEP IPCTAHWHFG Q

Genular Protein ID: 3991935322

Symbol: Q5TD07_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5TD07

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 3 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 193
  • Mass: 21537
  • Checksum: A298293859C3C38E
  • Sequence:
    • MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNLEPR ATDKDITGTL 
SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QGKLALLSVT TGGTAEMYTK 
TGVNGDSRYF LWPLQHGTLH FCGFKVLAPQ ISFAPEIASE EERKGMVAAW SQRLQTIWKE 
EPIPCTAHWH FGQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.