Details for: NMT1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 332.9578
Cell Significance Index: -51.7900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 222.3989
Cell Significance Index: -56.4100 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 152.6772
Cell Significance Index: -62.9000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 124.0567
Cell Significance Index: -58.5700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 119.0625
Cell Significance Index: -48.3700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 106.2433
Cell Significance Index: -54.6500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 50.8933
Cell Significance Index: -48.5900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 46.7657
Cell Significance Index: -57.6600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 20.3706
Cell Significance Index: -54.5700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 15.2501
Cell Significance Index: -46.8400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 14.8959
Cell Significance Index: -58.7800 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 14.1918
Cell Significance Index: -31.0600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1670
Cell Significance Index: 430.0500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.1135
Cell Significance Index: 259.8700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.1099
Cell Significance Index: 380.3400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.5459
Cell Significance Index: 310.1000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.4568
Cell Significance Index: 91.8200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.4494
Cell Significance Index: 38.7000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 1.4236
Cell Significance Index: 16.9700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.4079
Cell Significance Index: 12.9700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.2958
Cell Significance Index: 210.7500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.9492
Cell Significance Index: 24.4000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.8370
Cell Significance Index: 23.3900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7400
Cell Significance Index: 511.8400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.7215
Cell Significance Index: 258.7800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.7092
Cell Significance Index: 97.3900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.6801
Cell Significance Index: 31.9700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.6709
Cell Significance Index: 18.2600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.6681
Cell Significance Index: 51.2700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.6363
Cell Significance Index: 28.8400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.6355
Cell Significance Index: 18.3100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.6275
Cell Significance Index: 277.4500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.5993
Cell Significance Index: 27.9400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.5982
Cell Significance Index: 76.6900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.5817
Cell Significance Index: 317.6900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4304
Cell Significance Index: 42.5800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3873
Cell Significance Index: 20.1200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.2935
Cell Significance Index: 20.7600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2816
Cell Significance Index: 19.4800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1709
Cell Significance Index: 315.2700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1646
Cell Significance Index: 253.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1583
Cell Significance Index: 3.4300 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1581
Cell Significance Index: 18.6400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1577
Cell Significance Index: 9.7000 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.1262
Cell Significance Index: 3.0800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1117
Cell Significance Index: 5.8700 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.1050
Cell Significance Index: 2.0500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1017
Cell Significance Index: 17.3600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1015
Cell Significance Index: 19.3200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0897
Cell Significance Index: 2.5700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0897
Cell Significance Index: 168.9600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0872
Cell Significance Index: 78.7500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0606
Cell Significance Index: 82.4400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0475
Cell Significance Index: 3.1900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0360
Cell Significance Index: 1.2700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0244
Cell Significance Index: 1.3700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0003
Cell Significance Index: 0.2100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0156
Cell Significance Index: -7.0800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0172
Cell Significance Index: -12.6400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0241
Cell Significance Index: -17.8500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0252
Cell Significance Index: -15.7400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0336
Cell Significance Index: -25.4400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0771
Cell Significance Index: -43.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0981
Cell Significance Index: -12.6700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1366
Cell Significance Index: -2.9100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1605
Cell Significance Index: -33.8200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1674
Cell Significance Index: -4.4900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1718
Cell Significance Index: -20.0200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1739
Cell Significance Index: -11.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1772
Cell Significance Index: -50.9900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1933
Cell Significance Index: -22.1500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1947
Cell Significance Index: -19.8900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2051
Cell Significance Index: -29.8100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2090
Cell Significance Index: -15.5800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.2236
Cell Significance Index: -24.3200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2789
Cell Significance Index: -14.5300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3249
Cell Significance Index: -14.3700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3574
Cell Significance Index: -40.8000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3784
Cell Significance Index: -6.3300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4219
Cell Significance Index: -14.6600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4758
Cell Significance Index: -49.5400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.4881
Cell Significance Index: -6.6600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4899
Cell Significance Index: -18.5500 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5250
Cell Significance Index: -41.5800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.5500
Cell Significance Index: -11.4100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5742
Cell Significance Index: -9.8400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8015
Cell Significance Index: -49.1400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.8265
Cell Significance Index: -23.5900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.8484
Cell Significance Index: -12.5300 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.8646
Cell Significance Index: -7.0500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.8752
Cell Significance Index: -20.9900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.8909
Cell Significance Index: -28.5400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.9534
Cell Significance Index: -25.0700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.9549
Cell Significance Index: -16.0900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.0617
Cell Significance Index: -22.7000 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: -1.1131
Cell Significance Index: -8.5800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -1.1254
Cell Significance Index: -20.8000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.1597
Cell Significance Index: -34.0600 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -1.1729
Cell Significance Index: -24.5500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -1.1813
Cell Significance Index: -19.0600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 319081890
Symbol: NMT1_HUMAN
Name: Myristoyl-CoA:protein N-myristoyltransferase 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9353336
Title: Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction.
PubMed ID: 9353336
PubMed ID: 9506952
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1570339
Title: Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae.
PubMed ID: 1570339
PubMed ID: 9677304
Title: Characterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzyme.
PubMed ID: 9677304
DOI: 10.1042/bj3330491
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22865860
Title: Identification and characterization of an extramitochondrial human 3-Hydroxy-3-methylglutaryl-CoA lyase.
PubMed ID: 22865860
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 32686708
Title: N-myristoyltransferase-1 is necessary for lysosomal degradation and mTORC1 activation in cancer cells.
PubMed ID: 32686708
PubMed ID: 34999170
Title: N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.
PubMed ID: 34999170
PubMed ID: 25255805
Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
PubMed ID: 25255805
DOI: 10.1038/ncomms5919
PubMed ID: 32103017
Title: NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
PubMed ID: 32103017
PubMed ID: 32111831
Title: High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
PubMed ID: 32111831
Sequence Information:
- Length: 496
- Mass: 56806
- Checksum: 7661140D3837BE7A
- Sequence:
MADESETAVK PPAPPLPQMM EGNGNGHEHC SDCENEEDNS YNRGGLSPAN DTGAKKKKKK QKKKKEKGSE TDSAQDQPVK MNSLPAERIQ EIQKAIELFS VGQGPAKTME EASKRSYQFW DTQPVPKLGE VVNTHGPVEP DKDNIRQEPY TLPQGFTWDA LDLGDRGVLK ELYTLLNENY VEDDDNMFRF DYSPEFLLWA LRPPGWLPQW HCGVRVVSSR KLVGFISAIP ANIHIYDTEK KMVEINFLCV HKKLRSKRVA PVLIREITRR VHLEGIFQAV YTAGVVLPKP VGTCRYWHRS LNPRKLIEVK FSHLSRNMTM QRTMKLYRLP ETPKTAGLRP METKDIPVVH QLLTRYLKQF HLTPVMSQEE VEHWFYPQEN IIDTFVVENA NGEVTDFLSF YTLPSTIMNH PTHKSLKAAY SFYNVHTQTP LLDLMSDALV LAKMKGFDVF NALDLMENKT FLEKLKFGIG DGNLQYYLYN WKCPSMGAEK VGLVLQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.