Details for: NR4A2

Gene ID: 4929

Symbol: NR4A2

Ensembl ID: ENSG00000153234

Description: nuclear receptor subfamily 4 group A member 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 251.6953
    Cell Significance Index: -39.1500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 135.1110
    Cell Significance Index: -34.2700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 101.5859
    Cell Significance Index: -41.2700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 89.9978
    Cell Significance Index: -42.4900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 85.1891
    Cell Significance Index: -43.8200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 43.8757
    Cell Significance Index: -41.8900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.9233
    Cell Significance Index: -39.3600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 12.0692
    Cell Significance Index: -37.0700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 10.9674
    Cell Significance Index: -29.3800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.2786
    Cell Significance Index: -40.5600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.1005
    Cell Significance Index: -15.5400
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 6.5664
    Cell Significance Index: 37.6500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 2.0793
    Cell Significance Index: 48.0400
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 2.0568
    Cell Significance Index: 5.5100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.1892
    Cell Significance Index: 21.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.0046
    Cell Significance Index: 117.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9669
    Cell Significance Index: 45.0800
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.9158
    Cell Significance Index: 9.7300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8393
    Cell Significance Index: 43.6000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8211
    Cell Significance Index: 156.2600
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.8033
    Cell Significance Index: 4.3800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7398
    Cell Significance Index: 327.1000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.6454
    Cell Significance Index: 18.5000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6415
    Cell Significance Index: 82.2400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5931
    Cell Significance Index: 535.5100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5139
    Cell Significance Index: 83.5800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.4783
    Cell Significance Index: 33.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3971
    Cell Significance Index: 39.2800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3217
    Cell Significance Index: 39.5600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2968
    Cell Significance Index: 162.0900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2869
    Cell Significance Index: 51.7300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2846
    Cell Significance Index: 12.9000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2146
    Cell Significance Index: 5.8400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1435
    Cell Significance Index: 19.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1310
    Cell Significance Index: 14.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0975
    Cell Significance Index: 2.8100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0569
    Cell Significance Index: 11.4100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0338
    Cell Significance Index: 15.3500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0294
    Cell Significance Index: 18.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0291
    Cell Significance Index: 3.7600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0270
    Cell Significance Index: 0.9500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0120
    Cell Significance Index: 22.6500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0214
    Cell Significance Index: -39.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0230
    Cell Significance Index: -17.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0242
    Cell Significance Index: -37.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0260
    Cell Significance Index: -19.7100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0280
    Cell Significance Index: -19.3500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0288
    Cell Significance Index: -18.0000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0307
    Cell Significance Index: -0.2500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0317
    Cell Significance Index: -43.1100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0388
    Cell Significance Index: -21.8600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0419
    Cell Significance Index: -7.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0469
    Cell Significance Index: -4.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0523
    Cell Significance Index: -1.4000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0552
    Cell Significance Index: -40.5000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0722
    Cell Significance Index: -4.6600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0815
    Cell Significance Index: -3.8300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0851
    Cell Significance Index: -10.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0921
    Cell Significance Index: -19.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0938
    Cell Significance Index: -6.4900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0979
    Cell Significance Index: -28.1600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0982
    Cell Significance Index: -35.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1207
    Cell Significance Index: -9.2700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1471
    Cell Significance Index: -8.8300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1574
    Cell Significance Index: -31.2400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2284
    Cell Significance Index: -11.5400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2325
    Cell Significance Index: -33.8000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2640
    Cell Significance Index: -30.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2695
    Cell Significance Index: -30.8800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2984
    Cell Significance Index: -22.2400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3534
    Cell Significance Index: -36.8000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3614
    Cell Significance Index: -10.1000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3646
    Cell Significance Index: -14.9400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4354
    Cell Significance Index: -5.9400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4466
    Cell Significance Index: -30.0300
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.4493
    Cell Significance Index: -7.9400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4903
    Cell Significance Index: -5.5700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4998
    Cell Significance Index: -30.7200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5177
    Cell Significance Index: -10.7400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5220
    Cell Significance Index: -13.9900
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: -0.5250
    Cell Significance Index: -10.9500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5407
    Cell Significance Index: -33.1500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5433
    Cell Significance Index: -43.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5448
    Cell Significance Index: -30.5700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5712
    Cell Significance Index: -18.3000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5779
    Cell Significance Index: -30.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5996
    Cell Significance Index: -12.9900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6296
    Cell Significance Index: -39.6800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6415
    Cell Significance Index: -33.6800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6731
    Cell Significance Index: -17.7000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6862
    Cell Significance Index: -11.7600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.7459
    Cell Significance Index: -11.5400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.7527
    Cell Significance Index: -21.4800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7883
    Cell Significance Index: -25.8100
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: -0.7914
    Cell Significance Index: -5.2500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.8022
    Cell Significance Index: -29.4500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.8561
    Cell Significance Index: -37.2300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.9209
    Cell Significance Index: -40.7400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.9284
    Cell Significance Index: -18.1200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.9346
    Cell Significance Index: -19.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transcriptional regulation:** NR4A2 acts as a transcription factor, binding to specific DNA sequences and regulating the expression of target genes involved in various cellular processes. 2. **Cellular localization:** NR4A2 is primarily found in the nucleus, where it regulates transcription and interacts with other transcription factors and co-regulators. 3. **Immune cell expression:** NR4A2 is significantly expressed in immune cells, such as decidual natural killer cells, memory T cells, and lung macrophages, where it plays a role in regulating immune responses and inflammation. 4. **Neural expression:** NR4A2 is also expressed in neural tissues, where it regulates the development and function of dopamine-producing neurons. **Pathways and Functions:** 1. **Canonical Wnt signaling pathway:** NR4A2 interacts with β-catenin and other components of the Wnt signaling pathway to regulate cell proliferation, differentiation, and survival. 2. **Dopamine biosynthesis:** NR4A2 regulates the expression of genes involved in dopamine biosynthesis, including tyrosine hydroxylase, dopamine β-hydroxylase, and dopamine transporter. 3. **Neurodevelopment:** NR4A2 plays a crucial role in the development and differentiation of dopamine-producing neurons, including those in the midbrain and habenula. 4. **Immune responses:** NR4A2 regulates the expression of genes involved in immune responses, including those involved in inflammation, cytokine production, and antigen presentation. **Clinical Significance:** 1. **Neurodegenerative diseases:** NR4A2 has been implicated in various neurodegenerative diseases, including Parkinson's disease, Huntington's disease, and schizophrenia, where it regulates dopamine signaling and neuronal survival. 2. **Immune-related disorders:** NR4A2 has been linked to immune-related disorders, including multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease, where it regulates immune responses and inflammation. 3. **Cancer:** NR4A2 has been implicated in various types of cancer, including leukemia, lymphoma, and breast cancer, where it regulates cell proliferation, differentiation, and survival. 4. **Molecular diagnostics:** NR4A2 has been used as a biomarker for various diseases, including cancer and neurodegenerative disorders, where its expression levels can be used to diagnose and monitor disease progression. In conclusion, NR4A2 is a critical transcription factor that regulates various cellular processes, including transcription, differentiation, and survival, and has been implicated in various physiological and pathological processes, including immune responses, neurodegenerative diseases, and cancer. Further research is needed to fully understand the mechanisms by which NR4A2 regulates these processes and to explore its potential as a therapeutic target for various diseases.

Genular Protein ID: 1582362056

Symbol: NR4A2_HUMAN

Name: Nuclear receptor subfamily 4 group A member 2

UniProtKB Accession Codes:

P43354 Q16311 Q53RZ2 Q6NXU0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EMBL 10 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 45 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 4 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7877627

Title: NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.

PubMed ID: 7877627

DOI: 10.1210/mend.8.11.7877627

PubMed ID: 10216262

Title: Molecular cloning of the human Nurr1 gene: characterization of the human gene and cDNAs.

PubMed ID: 10216262

DOI: 10.1016/s0378-1119(99)00065-7

PubMed ID: 10216261

Title: Organization of the human orphan nuclear receptor Nurr1 gene.

PubMed ID: 10216261

DOI: 10.1016/s0378-1119(99)00064-5

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7706727

Title: cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line.

PubMed ID: 7706727

PubMed ID: 15716272

Title: Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.

PubMed ID: 15716272

DOI: 10.1074/jbc.m413175200

PubMed ID: 17184956

Title: Induction of tyrosine hydroxylase expression by the transcription factor Pitx3.

PubMed ID: 17184956

DOI: 10.1016/j.ijdevneu.2006.11.003

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23283970

Title: Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress.

PubMed ID: 23283970

DOI: 10.1074/jbc.m112.439190

PubMed ID: 12774125

Title: Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors.

PubMed ID: 12774125

DOI: 10.1038/nature01645

PubMed ID: 31428396

Title: Heterozygous loss of function of NR4A2 is associated with intellectual deficiency, rolandic epilepsy, and language impairment.

PubMed ID: 31428396

DOI: 10.1002/ccr3.2260

PubMed ID: 32366965

Title: De novo variants of NR4A2 are associated with neurodevelopmental disorder and epilepsy.

PubMed ID: 32366965

DOI: 10.1038/s41436-020-0815-4

PubMed ID: 31922365

Title: Loss-of-Function Mutations in NR4A2 Cause Dopa-Responsive Dystonia Parkinsonism.

PubMed ID: 31922365

DOI: 10.1002/mds.27982

PubMed ID: 33585677

Title: NR4A2 Mutations Can Cause Intellectual Disability and Language Impairment With Persistent Dystonia-Parkinsonism.

PubMed ID: 33585677

DOI: 10.1212/nxg.0000000000000543

Sequence Information:

  • Length: 598
  • Mass: 66591
  • Checksum: 28D8199AACE3E211
  • Sequence:
    • MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE ITATTSLPSF 
STFMDNYSTG YDVKPPCLYQ MPLSGQQSSI KVEDIQMHNY QQHSHLPPQS EEMMPHSGSV 
YYKPSSPPTP TTPGFQVQHS PMWDDPGSLH NFHQNYVATT HMIEQRKTPV SRLSLFSFKQ 
SPPGTPVSSC QMRFDGPLHV PMNPEPAGSH HVVDGQTFAV PNPIRKPASM GFPGLQIGHA 
SQLLDTQVPS PPSRGSPSNE GLCAVCGDNA ACQHYGVRTC EGCKGFFKRT VQKNAKYVCL 
ANKNCPVDKR RRNRCQYCRF QKCLAVGMVK EVVRTDSLKG RRGRLPSKPK SPQEPSPPSP 
PVSLISALVR AHVDSNPAMT SLDYSRFQAN PDYQMSGDDT QHIQQFYDLL TGSMEIIRGW 
AEKIPGFADL PKADQDLLFE SAFLELFVLR LAYRSNPVEG KLIFCNGVVL HRLQCVRGFG 
EWIDSIVEFS SNLQNMNIDI SAFSCIAALA MVTERHGLKE PKRVEELQNK IVNCLKDHVT 
FNNGGLNRPN YLSKLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPAIIDK LFLDTLPF

Genular Protein ID: 2803980321

Symbol: Q53EL4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53EL4

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 10 Gene3D 2 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 4 PROSITE 5 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 598
  • Mass: 66601
  • Checksum: A8F4E469BE11FE50
  • Sequence:
    • MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE ITATTSLPSF 
STFMDNYSTG YDVKPPCLYQ MPLSGQQSSI KVEDIQMHNY QQHSHLPPQS EEMMPHSGSV 
YYKPSSPPTP TTPGFQVQHS PMWDDPGSLH NFHQNYVATT HMIEQRKTPV SRLSLFSFKQ 
SPPGTPVSSC QMRFDGPLHV PMNPEPAGSH HVVDGQTFAV PNPIRKPASM GFPGLQIGHA 
SQLLDTQVPS PPSRGPPSNE GLCAVCGDNA ACQHYGVRTC EGCKGFFKRT VQKNAKYVCL 
ANKNCPVDKR RRNRCQYCRF QKCLAVGMVK EVVRTDSLKG RRGRLPSKPK SPQEPSPPSP 
PVSLISALVR AHVDSNPAMT SLDYSRFQAN PDYQMSGDDT QHIQQFYDLL TGSMEIIRGW 
AEKIPGFADL PKADQDLLFE SAFLELFVLR LAYRSNPVEG KLIFCNGVVL HRLQCVRGFG 
EWIDSIVEFS SNLQNMNIDI SAFSCIAALA MVTERHGLKE PKRVEELQNK IVNCLKDHVT 
FNNGGLNRPN YLSKLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPAIIDK LFLDTLPF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.