Details for: PBX3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 288.3084
Cell Significance Index: -44.8500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 175.4432
Cell Significance Index: -44.5000 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 104.4065
Cell Significance Index: -43.0100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 96.9663
Cell Significance Index: -45.7800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 88.6754
Cell Significance Index: -36.0300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 37.8269
Cell Significance Index: -36.1200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 36.9235
Cell Significance Index: -45.5300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 16.4996
Cell Significance Index: -44.2000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 15.5717
Cell Significance Index: -34.0800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 11.5736
Cell Significance Index: -45.6700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 4.2246
Cell Significance Index: 159.9800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 4.1384
Cell Significance Index: 183.0500 - Cell Name: preadipocyte (CL0002334)
Fold Change: 3.1367
Cell Significance Index: 61.2200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 3.0812
Cell Significance Index: 236.4500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.7256
Cell Significance Index: 58.2600 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 2.6246
Cell Significance Index: 27.3400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.2937
Cell Significance Index: 128.7100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.9379
Cell Significance Index: 695.0800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.8239
Cell Significance Index: 361.9500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.3698
Cell Significance Index: 38.2800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.2392
Cell Significance Index: 857.0500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.2027
Cell Significance Index: 75.8000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.1358
Cell Significance Index: 24.8700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.0945
Cell Significance Index: 27.3600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 1.0238
Cell Significance Index: 1576.1000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8165
Cell Significance Index: 80.7700 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.7939
Cell Significance Index: 11.4000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.6578
Cell Significance Index: 1238.6200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6577
Cell Significance Index: 106.9700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.6434
Cell Significance Index: 7.6700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5972
Cell Significance Index: 119.8000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.5391
Cell Significance Index: 34.7800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5043
Cell Significance Index: 455.3300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.4588
Cell Significance Index: 846.1100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.3889
Cell Significance Index: 528.7800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.3739
Cell Significance Index: 5.5200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3703
Cell Significance Index: 45.5300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3637
Cell Significance Index: 65.5700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3417
Cell Significance Index: 21.0000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.3017
Cell Significance Index: 6.4300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2925
Cell Significance Index: 31.8100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.2642
Cell Significance Index: 30.7900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1945
Cell Significance Index: 26.7100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1157
Cell Significance Index: 73.4500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0905
Cell Significance Index: 40.0000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0852
Cell Significance Index: 16.2200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0608
Cell Significance Index: 0.8300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0571
Cell Significance Index: 7.3200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0561
Cell Significance Index: 25.4800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0087
Cell Significance Index: 0.2500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0069
Cell Significance Index: 0.1500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0003
Cell Significance Index: 0.1600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0186
Cell Significance Index: -2.7000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0202
Cell Significance Index: -14.9700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0251
Cell Significance Index: -0.4300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0302
Cell Significance Index: -17.0500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0318
Cell Significance Index: -19.8300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0415
Cell Significance Index: -1.8800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0426
Cell Significance Index: -31.2600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0503
Cell Significance Index: -3.4800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0565
Cell Significance Index: -42.7900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0572
Cell Significance Index: -2.0100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0581
Cell Significance Index: -9.9200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0839
Cell Significance Index: -17.6700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1186
Cell Significance Index: -7.2700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1261
Cell Significance Index: -6.5700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1302
Cell Significance Index: -37.4700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1306
Cell Significance Index: -2.1900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1354
Cell Significance Index: -13.8400 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.1925
Cell Significance Index: -2.4000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2079
Cell Significance Index: -23.8200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2169
Cell Significance Index: -3.1200 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.2174
Cell Significance Index: -1.9300 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: -0.2269
Cell Significance Index: -1.4000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2303
Cell Significance Index: -5.9200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2443
Cell Significance Index: -25.4400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2696
Cell Significance Index: -19.0700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2830
Cell Significance Index: -32.3000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3003
Cell Significance Index: -35.4200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3058
Cell Significance Index: -39.5100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3317
Cell Significance Index: -17.2300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3812
Cell Significance Index: -12.2100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.4362
Cell Significance Index: -29.3300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4378
Cell Significance Index: -32.6300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4601
Cell Significance Index: -21.6300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4899
Cell Significance Index: -38.8000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.4916
Cell Significance Index: -22.9200 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.4920
Cell Significance Index: -6.2100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.5061
Cell Significance Index: -8.5300 - Cell Name: mesodermal cell (CL0000222)
Fold Change: -0.5399
Cell Significance Index: -3.3800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.6009
Cell Significance Index: -16.1000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.6121
Cell Significance Index: -14.6800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.6633
Cell Significance Index: -13.7600 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.6643
Cell Significance Index: -9.8100 - Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
Fold Change: -0.7051
Cell Significance Index: -6.4100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7255
Cell Significance Index: -38.0900 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.7511
Cell Significance Index: -6.2000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.7597
Cell Significance Index: -4.5900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7661
Cell Significance Index: -26.6200 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.7955
Cell Significance Index: -10.2000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 768111084
Symbol: PBX3_HUMAN
Name: Pre-B-cell leukemia transcription factor 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1682799
Title: PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.
PubMed ID: 1682799
PubMed ID: 11579467
Title: Novel alternative PBX3 isoforms in leukemia cells with distinct interaction specificities.
PubMed ID: 11579467
DOI: 10.1002/gcc.1190
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7910944
Title: Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.
PubMed ID: 7910944
PubMed ID: 10825160
Title: Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA.
PubMed ID: 10825160
Sequence Information:
- Length: 434
- Mass: 47190
- Checksum: 81987E4C80C22069
- Sequence:
MDDQSRMLQT LAGVNLAGHS VQGGMALPPP PHGHEGADGD GRKQDIGDIL HQIMTITDQS LDEAQAKKHA LNCHRMKPAL FSVLCEIKEK TGLSIRGAQE EDPPDPQLMR LDNMLLAEGV SGPEKGGGSA AAAAAAAASG GSSDNSIEHS DYRAKLTQIR QIYHTELEKY EQACNEFTTH VMNLLREQSR TRPISPKEIE RMVGIIHRKF SSIQMQLKQS TCEAVMILRS RFLDARRKRR NFSKQATEIL NEYFYSHLSN PYPSEEAKEE LAKKCSITVS QVSNWFGNKR IRYKKNIGKF QEEANLYAAK TAVTAAHAVA AAVQNNQTNS PTTPNSGSSG SFNLPNSGDM FMNMQSLNGD SYQGSQVGAN VQSQVDTLRH VINQTGGYSD GLGGNSLYSP HNLNANGGWQ DATTPSSVTS PTEGPGSVHS DTSN
Genular Protein ID: 1782396198
Symbol: Q96AL5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 367
- Mass: 39924
- Checksum: 0FE7B826B9983265
- Sequence:
EKTGLSIRGA QEEDPPDPQL MRLDNMLLAE GVSGPEKGGG SAAAAAAAAA SGGSSDNSIE HSDYRAKLTQ IRQIYHTELE KYEQACNEFT THVMNLLREQ SRTRPISPKE IERMVGIIHR KFSSIQMQLK QSTCEAVMIL RSRFLDARRK RRNFSKQATE ILNEYFYSHL SNPYPSEEAK EELAKKCSIT VSQSLVKDPK ERGSKGSDIQ PTSVVSNWFG NKRIRYKKNI GKFQEEANLY AAKTAVTAAH AVAAAVQNNQ TNSPTTPNSG SSGSFNLPNS GDMFMNMQSL NGDSYQGSQV GANVQSQVDT LRHVINQTGG YSDGLGGNSL YSPHNLNANG GWQDATTPSS VTSPTEGPGS VHSDTSN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.