Details for: PHF20

Gene ID: 51230

Symbol: PHF20

Ensembl ID: ENSG00000025293

Description: PHD finger protein 20

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 381.3682
    Cell Significance Index: -59.3200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 209.7039
    Cell Significance Index: -53.1900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 139.2468
    Cell Significance Index: -56.5700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 139.0740
    Cell Significance Index: -65.6600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 123.1567
    Cell Significance Index: -63.3500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 59.5762
    Cell Significance Index: -56.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.8534
    Cell Significance Index: -62.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.4639
    Cell Significance Index: -54.8200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.8482
    Cell Significance Index: -54.8200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 16.2542
    Cell Significance Index: -64.1400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 15.0599
    Cell Significance Index: -32.9600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.1391
    Cell Significance Index: 80.6900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.0092
    Cell Significance Index: 398.7400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9330
    Cell Significance Index: 387.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.7858
    Cell Significance Index: 208.1200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.5384
    Cell Significance Index: 106.3900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.4534
    Cell Significance Index: 111.5400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2152
    Cell Significance Index: 1097.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.9486
    Cell Significance Index: 26.5100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8918
    Cell Significance Index: 616.7700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8559
    Cell Significance Index: 306.9800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7809
    Cell Significance Index: 84.9400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.7668
    Cell Significance Index: 18.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7323
    Cell Significance Index: 119.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.7244
    Cell Significance Index: 40.6500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6923
    Cell Significance Index: 85.1200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6836
    Cell Significance Index: 123.2300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6647
    Cell Significance Index: 91.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6183
    Cell Significance Index: 337.6500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6176
    Cell Significance Index: 46.0300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5458
    Cell Significance Index: 33.5500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5226
    Cell Significance Index: 33.7200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5034
    Cell Significance Index: 222.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3876
    Cell Significance Index: 729.8700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.3625
    Cell Significance Index: 9.6800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3387
    Cell Significance Index: 6.6100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3369
    Cell Significance Index: 64.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2840
    Cell Significance Index: 33.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2569
    Cell Significance Index: 12.0800
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.2355
    Cell Significance Index: 3.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2166
    Cell Significance Index: 27.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2126
    Cell Significance Index: 289.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2043
    Cell Significance Index: 26.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1802
    Cell Significance Index: 114.4300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1758
    Cell Significance Index: 9.2300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1363
    Cell Significance Index: 6.0300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1215
    Cell Significance Index: 4.6000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1213
    Cell Significance Index: 186.7400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1200
    Cell Significance Index: 1.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1196
    Cell Significance Index: 220.5000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1091
    Cell Significance Index: 1.8700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0705
    Cell Significance Index: 32.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0646
    Cell Significance Index: 1.8600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0435
    Cell Significance Index: 3.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0242
    Cell Significance Index: 1.1300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0198
    Cell Significance Index: 0.5400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0029
    Cell Significance Index: -0.0400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0165
    Cell Significance Index: -0.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0220
    Cell Significance Index: -16.3200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0231
    Cell Significance Index: -1.4600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0321
    Cell Significance Index: -20.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0359
    Cell Significance Index: -1.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0418
    Cell Significance Index: -7.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0522
    Cell Significance Index: -38.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0568
    Cell Significance Index: -43.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0888
    Cell Significance Index: -50.0600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0971
    Cell Significance Index: -9.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1226
    Cell Significance Index: -12.5200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1779
    Cell Significance Index: -5.1000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1979
    Cell Significance Index: -28.7600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2013
    Cell Significance Index: -57.9200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2065
    Cell Significance Index: -43.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2543
    Cell Significance Index: -17.1000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3106
    Cell Significance Index: -14.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3419
    Cell Significance Index: -39.1700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3441
    Cell Significance Index: -5.0800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3665
    Cell Significance Index: -7.8400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3922
    Cell Significance Index: -40.8400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3944
    Cell Significance Index: -20.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4599
    Cell Significance Index: -15.9800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4820
    Cell Significance Index: -11.5600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5055
    Cell Significance Index: -57.7000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5115
    Cell Significance Index: -13.7100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5288
    Cell Significance Index: -8.8500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6079
    Cell Significance Index: -15.5300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6447
    Cell Significance Index: -13.7300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.6824
    Cell Significance Index: -14.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7109
    Cell Significance Index: -56.3100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.8582
    Cell Significance Index: -24.4900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.8695
    Cell Significance Index: -19.0400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.9004
    Cell Significance Index: -24.0900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.9461
    Cell Significance Index: -6.4100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.0273
    Cell Significance Index: -30.1700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.0513
    Cell Significance Index: -19.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0607
    Cell Significance Index: -65.0300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.0697
    Cell Significance Index: -22.3900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -1.1284
    Cell Significance Index: -16.2300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.1453
    Cell Significance Index: -6.9200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.1613
    Cell Significance Index: -30.5400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.1921
    Cell Significance Index: -29.8000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PHF20 is a 184 amino acid protein, consisting of a PHD finger domain, a coiled-coil domain, and a C-terminal tail. Its PHD finger domain is essential for binding to histone H3 and other histones, facilitating the recruitment of WDR5-containing complexes to specific genomic regions. PHF20 has been shown to interact with various proteins, including TP53, MLL1, and NSL, which are involved in DNA damage response, epigenetic regulation, and transcriptional control. **Pathways and Functions:** PHF20 is involved in several key pathways, including: 1. **Epigenetic Regulation by WDR5-containing Histone-Modifying Complexes:** PHF20's interaction with WDR5 enables the recruitment of histone-modifying complexes to specific genomic regions, leading to the regulation of gene expression and maintaining genome stability. 2. **DNA Damage Response:** PHF20's interaction with TP53, a key tumor suppressor protein, regulates TP53 activity, stability, and expression, which are critical for maintaining genome stability in response to DNA damage. 3. **Cell Cycle Checkpoints:** PHF20's regulation of the G1/S cell cycle checkpoint ensures proper cell cycle progression and prevents the propagation of damaged cells. 4. **Transcriptional Regulation by RNA Polymerase II:** PHF20's interaction with RNA polymerase II regulates transcriptional elongation and the expression of genes involved in DNA damage response and cell cycle checkpoints. 5. **Histone Acetylation:** PHF20's interaction with HATS acetylates histones, leading to the regulation of gene expression and maintaining genome stability. **Clinical Significance:** Dysregulation of PHF20 has been implicated in various diseases, including: 1. **Cancer:** PHF20 can act as an oncogene or tumor suppressor, depending on the cellular context, and its dysregulation has been linked to cancer progression and poor prognosis. 2. **Neurological Disorders:** PHF20's dysregulation has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease, where it may contribute to the regulation of gene expression and epigenetic modifications. 3. **Autoimmune Diseases:** PHF20's dysregulation has been linked to autoimmune diseases, including rheumatoid arthritis and lupus, where it may contribute to the regulation of gene expression and immune responses. In conclusion, PHF20 is a multifaceted protein that plays a critical role in maintaining genome stability and regulating gene expression through histone modifications. Its dysregulation has been implicated in various diseases, highlighting the importance of PHF20 in human health and disease. Further research is needed to fully elucidate the mechanisms by which PHF20 regulates gene expression and epigenetic modifications, and to explore its potential as a therapeutic target for various diseases.

Genular Protein ID: 780833966

Symbol: PHF20_HUMAN

Name: PHD finger protein 20

UniProtKB Accession Codes:

Q9BVI0 A7E235 B2RB56 E1P5S3 Q566Q2 Q5JWY9 Q66K49 Q9BWV4 Q9BXA3 Q9BZW3 Q9H421 Q9H4J6 Q9NZ22

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 15 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 5 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12097419

Title: Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies.

PubMed ID: 12097419

DOI: 10.4049/jimmunol.169.2.1102

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11703362

Title: Glioma-expressed antigen 2 (GLEA2): a novel protein that can elicit immune responses in glioblastoma patients and some controls.

PubMed ID: 11703362

DOI: 10.1046/j.1365-2249.2001.01635.x

PubMed ID: 12800201

Title: Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries.

PubMed ID: 12800201

DOI: 10.1002/ijc.11208

PubMed ID: 15960975

Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.

PubMed ID: 15960975

DOI: 10.1016/j.cell.2005.04.031

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20018852

Title: Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.

PubMed ID: 20018852

DOI: 10.1074/jbc.c109.087981

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23452852

Title: Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination.

PubMed ID: 23452852

DOI: 10.1016/j.cell.2013.02.006

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 22449972

Title: Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins.

PubMed ID: 22449972

DOI: 10.1016/j.febslet.2012.02.012

PubMed ID: 22864287

Title: PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.

PubMed ID: 22864287

DOI: 10.1038/nsmb.2353

Sequence Information:

  • Length: 1012
  • Mass: 115386
  • Checksum: 1CDBADC23D007503
  • Sequence:
    • MTKHPPNRRG ISFEVGAQLE ARDRLKNWYP AHIEDIDYEE GKVLIHFKRW NHRYDEWFCW 
DSPYLRPLEK IQLRKEGLHE EDGSSEFQIN EQVLACWSDC RFYPAKVTAV NKDGTYTVKF 
YDGVVQTVKH IHVKAFSKDQ NIVGNARPKE TDHKSLSSSP DKREKFKEQR KATVNVKKDK 
EDKPLKTEKR PKQPDKEGKL ICSEKGKVSE KSLPKNEKED KENISENDRE YSGDAQVDKK 
PENDIVKSPQ ENLREPKRKR GRPPSIAPTA VDSNSQTLQP ITLELRRRKI SKGCEVPLKR 
PRLDKNSSQE KSKNYSENTD KDLSRRRSSR LSTNGTHEIL DPDLVVSDLV DTDPLQDTLS 
STKESEEGQL KSALEAGQVS SALTCHSFGD GSGAAGLELN CPSMGENTMK TEPTSPLVEL 
QEISTVEVTN TFKKTDDFGS SNAPAVDLDH KFRCKVVDCL KFFRKAKLLH YHMKYFHGME 
KSLEPEESPG KRHVQTRGPS ASDKPSQETL TRKRVSASSP TTKDKEKNKE KKFKEFVRVK 
PKKKKKKKKK TKPECPCSEE ISDTSQEPSP PKAFAVTRCG SSHKPGVHMS PQLHGPESGH 
HKGKVKALEE DNLSESSSES FLWSDDEYGQ DVDVTTNPDE ELDGDDRYDF EVVRCICEVQ 
EENDFMIQCE ECQCWQHGVC MGLLEENVPE KYTCYVCQDP PGQRPGFKYW YDKEWLSRGH 
MHGLAFLEEN YSHQNAKKIV ATHQLLGDVQ RVIEVLHGLQ LKMSILQSRE HPDLPLWCQP 
WKQHSGEGRS HFRNIPVTDT RSKEEAPSYR TLNGAVEKPR PLALPLPRSV EESYITSEHC 
YQKPRAYYPA VEQKLVVETR GSALDDAVNP LHENGDDSLS PRLGWPLDQD RSKGDSDPKP 
GSPKVKEYVS KKALPEEAPA RKLLDRGGEG LLSSQHQWQF NLLTHVESLQ DEVTHRMDSI 
EKELDVLESW LDYTGELEPP EPLARLPQLK HCIKQLLMDL GKVQQIALCC ST

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.