Details for: CRNKL1

Gene ID: 51340

Symbol: CRNKL1

Ensembl ID: ENSG00000101343

Description: crooked neck pre-mRNA splicing factor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 148.5742
    Cell Significance Index: -23.1100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 91.9401
    Cell Significance Index: -23.3200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 55.2399
    Cell Significance Index: -26.0800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 51.6914
    Cell Significance Index: -21.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.2573
    Cell Significance Index: -21.2500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.9926
    Cell Significance Index: -24.6500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.4047
    Cell Significance Index: -22.5200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.4495
    Cell Significance Index: -25.4500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.9390
    Cell Significance Index: -15.1700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.0209
    Cell Significance Index: -8.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2344
    Cell Significance Index: 134.2700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1397
    Cell Significance Index: 15.5500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0766
    Cell Significance Index: 972.0600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.0300
    Cell Significance Index: 167.5300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6148
    Cell Significance Index: 122.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.6036
    Cell Significance Index: 31.4400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5738
    Cell Significance Index: 26.0100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5182
    Cell Significance Index: 32.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4993
    Cell Significance Index: 68.5700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4805
    Cell Significance Index: 13.8500
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.4572
    Cell Significance Index: 3.8400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4501
    Cell Significance Index: 55.3400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4282
    Cell Significance Index: 29.6100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3840
    Cell Significance Index: 8.3200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3817
    Cell Significance Index: 68.8000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.3560
    Cell Significance Index: 8.9000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3482
    Cell Significance Index: 18.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3451
    Cell Significance Index: 69.2300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3179
    Cell Significance Index: 140.5300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2789
    Cell Significance Index: 152.3300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2125
    Cell Significance Index: 27.2400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2051
    Cell Significance Index: 141.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1864
    Cell Significance Index: 8.6900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1814
    Cell Significance Index: 11.7100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1525
    Cell Significance Index: 5.3600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1428
    Cell Significance Index: 14.1300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1345
    Cell Significance Index: 8.2700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1277
    Cell Significance Index: 9.0300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1225
    Cell Significance Index: 43.9400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1102
    Cell Significance Index: 3.0000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0886
    Cell Significance Index: 16.8600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0814
    Cell Significance Index: 2.1400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0770
    Cell Significance Index: 9.0900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0689
    Cell Significance Index: 3.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0681
    Cell Significance Index: 3.8200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0225
    Cell Significance Index: 0.4700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0004
    Cell Significance Index: 0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0026
    Cell Significance Index: -4.9800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0113
    Cell Significance Index: -8.2800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0126
    Cell Significance Index: -23.2100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0166
    Cell Significance Index: -25.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0174
    Cell Significance Index: -11.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0221
    Cell Significance Index: -30.1100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0258
    Cell Significance Index: -19.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0303
    Cell Significance Index: -22.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0420
    Cell Significance Index: -19.0800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0443
    Cell Significance Index: -24.9700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0491
    Cell Significance Index: -30.6500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0512
    Cell Significance Index: -5.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0570
    Cell Significance Index: -7.3700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0574
    Cell Significance Index: -4.2800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0622
    Cell Significance Index: -17.9000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0702
    Cell Significance Index: -8.1800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0797
    Cell Significance Index: -0.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0825
    Cell Significance Index: -9.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0885
    Cell Significance Index: -12.8600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0929
    Cell Significance Index: -15.8700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1191
    Cell Significance Index: -9.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1363
    Cell Significance Index: -3.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1482
    Cell Significance Index: -31.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1592
    Cell Significance Index: -3.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1867
    Cell Significance Index: -5.9800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1969
    Cell Significance Index: -3.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2074
    Cell Significance Index: -10.8900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.2142
    Cell Significance Index: -3.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2208
    Cell Significance Index: -14.8500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2256
    Cell Significance Index: -7.8400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2376
    Cell Significance Index: -18.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2416
    Cell Significance Index: -25.1600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2514
    Cell Significance Index: -2.3200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.2520
    Cell Significance Index: -2.7400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2532
    Cell Significance Index: -11.2000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2858
    Cell Significance Index: -7.3000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2914
    Cell Significance Index: -7.4900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2969
    Cell Significance Index: -8.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3396
    Cell Significance Index: -12.8600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3397
    Cell Significance Index: -4.0500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3445
    Cell Significance Index: -7.9600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3449
    Cell Significance Index: -5.9100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3687
    Cell Significance Index: -10.8300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3794
    Cell Significance Index: -10.1700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3801
    Cell Significance Index: -3.9400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4136
    Cell Significance Index: -25.3600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4329
    Cell Significance Index: -11.5800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4374
    Cell Significance Index: -10.4900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4545
    Cell Significance Index: -8.8700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4683
    Cell Significance Index: -5.3200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.5062
    Cell Significance Index: -9.3600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.5326
    Cell Significance Index: -11.3900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.5439
    Cell Significance Index: -16.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The CRNKL1 gene is a non-coding gene, meaning it does not encode a protein sequence. Instead, it regulates the expression of nearby genes through the modulation of RNA splicing. The gene is specifically expressed in cells undergoing rapid cell division, such as hematopoietic cells and smooth muscle fibers. CRNKL1 is a part of the U2-type catalytic step 2 spliceosome, a complex involved in the splicing of pre-mRNA. The gene's expression is significantly correlated with the presence of specific cell types, including polychromatophilic erythroblasts, hematopoietic oligopotent progenitor cells, and CD8-alpha-beta-positive alpha-beta intraepithelial T cells. **Pathways and Functions:** The CRNKL1 gene is integral to the following pathways: 1. **RNA Splicing:** CRNKL1 regulates the splicing of pre-mRNA into mature mRNA, ensuring accurate and efficient processing of RNA transcripts. 2. **Catalytic Step 2 Spliceosome:** CRNKL1 is a component of the U2-type catalytic step 2 spliceosome, a complex responsible for the precise splicing of pre-mRNA. 3. **Metabolism of RNA:** CRNKL1 is involved in the regulation of RNA metabolism, including the processing of capped intron-containing pre-mRNA. 4. **Nuclear Speck:** CRNKL1 is localized to nuclear specks, a type of nuclear structure involved in the regulation of gene expression and RNA processing. **Clinical Significance:** Dysregulation of the CRNKL1 gene has been implicated in various diseases, including: 1. **Hematological Disorders:** Mutations in CRNKL1 have been associated with hematological disorders, such as anemia and leukemia. 2. **Immune System Dysregulation:** Alterations in CRNKL1 expression have been linked to immune system dysregulation, including autoimmune diseases and cancer. 3. **Cancer:** CRNKL1 has been identified as a potential oncogene, with its expression correlated with cancer progression and metastasis. In conclusion, the CRNKL1 gene plays a critical role in the regulation of RNA splicing and metabolism, with significant implications for our understanding of various diseases. Further research is necessary to fully elucidate the functions and clinical significance of this enigmatic gene.

Genular Protein ID: 1291533283

Symbol: CRNL1_HUMAN

Name: Crooked neck-like protein 1

UniProtKB Accession Codes:

Q9BZJ0 A8K9T4 Q5JY64 Q8WYI5 Q9BZI9 Q9BZJ1 Q9BZJ2 Q9GZW7 Q9H8F8 Q9NQH5 Q9NYD8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 EMDB 20 Ensembl 3 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 22 PDBsum 22 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11342225

Title: Identification of the human crooked neck gene by comparative gene identification.

PubMed ID: 11342225

DOI: 10.1016/s0167-4781(00)00295-5

PubMed ID: 12084575

Title: Crooked neck is a component of the human spliceosome and implicated in the splicing process.

PubMed ID: 12084575

DOI: 10.1016/s0167-4781(02)00368-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 12801913

Title: A novel rat orthologue and homologue for the Drosophila crooked neck gene in neural stem cells and their immediate descendants.

PubMed ID: 12801913

DOI: 10.1093/jb/mvg079

PubMed ID: 15189447

Title: Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones.

PubMed ID: 15189447

DOI: 10.1111/j.1356-9597.2004.00742.x

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28502770

Title: An Atomic Structure of the Human Spliceosome.

PubMed ID: 28502770

DOI: 10.1016/j.cell.2017.04.033

PubMed ID: 28076346

Title: Cryo-EM structure of a human spliceosome activated for step 2 of splicing.

PubMed ID: 28076346

DOI: 10.1038/nature21079

PubMed ID: 33509932

Title: Structure of the activated human minor spliceosome.

PubMed ID: 33509932

DOI: 10.1126/science.abg0879

Sequence Information:

  • Length: 848
  • Mass: 100452
  • Checksum: E30A39E981BC50AC
  • Sequence:
    • MTATVENLTF QKDTLGNAVD KNTSRLELRS YSLAGRHGST EPLVLAWSSQ FRRLTWGCAL 
DALHRSPCVA ASQHGVTHLI RSSRTPHSTR CRKEDAQPGH HGNGAASVTA QARGQRSVLQ 
VPLPVPRSCL FSESFVVSVS SQSRFLASVP GTGVQRSTAA DMAASTAAGK QRIPKVAKVK 
NKAPAEVQIT AEQLLREAKE RELELLPPPP QQKITDEEEL NDYKLRKRKT FEDNIRKNRT 
VISNWIKYAQ WEESLKEIQR ARSIYERALD VDYRNITLWL KYAEMEMKNR QVNHARNIWD 
RAITTLPRVN QFWYKYTYME EMLGNVAGAR QVFERWMEWQ PEEQAWHSYI NFELRYKEVD 
RARTIYERFV LVHPDVKNWI KYARFEEKHA YFAHARKVYE RAVEFFGDEH MDEHLYVAFA 
KFEENQKEFE RVRVIYKYAL DRISKQDAQE LFKNYTIFEK KFGDRRGIED IIVSKRRFQY 
EEEVKANPHN YDAWFDYLRL VESDAEAEAV REVYERAIAN VPPIQEKRHW KRYIYLWINY 
ALYEELEAKD PERTRQVYQA SLELIPHKKF TFAKMWILYA QFEIRQKNLS LARRALGTSI 
GKCPKNKLFK VYIELELQLR EFDRCRKLYE KFLEFGPENC TSWIKFAELE TILGDIDRAR 
AIYELAISQP RLDMPEVLWK SYIDFEIEQE ETERTRNLYR RLLQRTQHVK VWISFAQFEL 
SSGKEGSLTK CRQIYEEANK TMRNCEEKEE RLMLLESWRS FEEEFGTASD KERVDKLMPE 
KVKKRRKVQT DDGSDAGWEE YFDYIFPEDA ANQPNLKLLA MAKLWKKQQQ EKEDAEHHPD 
EDVDESES

Genular Protein ID: 3711240627

Symbol: Q69YP1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q69YP1

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 5 SAM 2 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 728
  • Mass: 87367
  • Checksum: 35A849094C0AE8AE
  • Sequence:
    • VPLPVPRSCL FSESFVVSVS SQSRFLASVP GTGVQRSAAA DMAASTAAGK QRIPKVAKVK 
NKAPAEVQIT AEQLLREAKE RELELLPPPP QQKITDEEEL NDYKLRKRKT FEDNIRKNRT 
VISNWIKYAQ WEESLKEIQR ARSIYERALD VDYRNITLWL KYAEMEMKNR QVNHARNIWD 
RAITTLPRVN QFWYKYTYME EMLGNVAGAR QVFERWMEWQ PEEQAWHSYI NFELRYKEVD 
RARTIYERFV LVHPDVKNWI KYARFEEKHA YFAHARKVYE RAVEFFGDEH MDEHLYVAFA 
KFEENQKEFE RVRVIYKYAL DRISKQDAQE LFKNYTIFEK KFGDRRGIED IIVSKRRFQY 
EEEVKANPHN YDAWFDYLRL VESDAEAEAV REVYERAIAN VPPIQEKRHW KRYIYLWINY 
ALYEELEAKD PERTRQVYQA SLELIPHKKF TFAKMWILYA QFEIRQKNLS LARRALGTSI 
GKCPKNKLFK VYIELELQLR EFDRCRKLYE KFLEFGPENC TSWIKFAELE TILGDIDRAR 
AIYELAISQP RLDMPEVLWK SYIDFEIEQE ETERTRNLYR RLLQRTQHVK VWISFAQFEL 
SSGKEGSLTK CRQIYEEANK TMRNCEEKEE RLMLLESWRS FEEEFGTASD KERVDKLMPE 
KVKKRRKVQT DDGSDAGWEE YFDYIFPEDA ANQPNLKLLA MAKLWKKQQQ EKEDAEHHPD 
EDVDESES

Genular Protein ID: 2799541157

Symbol: Q5JY65_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5JY65

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 836
  • Mass: 99173
  • Checksum: B199BC385A8E9090
  • Sequence:
    • MTATVENLTF QKDTLGNAVD KNRRHGSTEP LVLAWSSQFR RLTWGCALDA LHRSPCVAAS 
QHGVTHLIRS SRTPHSTRCR KEDAQPGHHG NGAASVTAQA RGQRSVLQVP LPVPRSCLFS 
ESFVVSVSSQ SRFLASVPGT GVQRSTAADM AASTAAGKQR IPKVAKVKNK APAEVQITAE 
QLLREAKERE LELLPPPPQQ KITDEEELND YKLRKRKTFE DNIRKNRTVI SNWIKYAQWE 
ESLKEIQRAR SIYERALDVD YRNITLWLKY AEMEMKNRQV NHARNIWDRA ITTLPRVNQF 
WYKYTYMEEM LGNVAGARQV FERWMEWQPE EQAWHSYINF ELRYKEVDRA RTIYERFVLV 
HPDVKNWIKY ARFEEKHAYF AHARKVYERA VEFFGDEHMD EHLYVAFAKF EENQKEFERV 
RVIYKYALDR ISKQDAQELF KNYTIFEKKF GDRRGIEDII VSKRRFQYEE EVKANPHNYD 
AWFDYLRLVE SDAEAEAVRE VYERAIANVP PIQEKRHWKR YIYLWINYAL YEELEAKDPE 
RTRQVYQASL ELIPHKKFTF AKMWILYAQF EIRQKNLSLA RRALGTSIGK CPKNKLFKVY 
IELELQLREF DRCRKLYEKF LEFGPENCTS WIKFAELETI LGDIDRARAI YELAISQPRL 
DMPEVLWKSY IDFEIEQEET ERTRNLYRRL LQRTQHVKVW ISFAQFELSS GKEGSLTKCR 
QIYEEANKTM RNCEEKEERL MLLESWRSFE EEFGTASDKE RVDKLMPEKV KKRRKVQTDD 
GSDAGWEEYF DYIFPEDAAN QPNLKLLAMA KLWKKQQQEK EDAEHHPDED VDESES

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.