Details for: ATRAID
Gene ID: 51374
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: ATRAID
Ensembl ID: ENSG00000138085
Description: all-trans retinoic acid induced differentiation factor
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 61.33rCSI 53.93%PRS 12.9
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CSI 60.2rCSI 57.95%PRS 18.38
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CSI 54.25rCSI 53.36%PRS 19.28
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CSI 52.71rCSI 55.09%PRS 18.58
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CSI 48.72rCSI 51.04%PRS 18.97
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CSI 46.74rCSI 38.75%PRS 16.8
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CSI 33.25rCSI 32.06%PRS 12.72
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CSI 31.1rCSI 38.47%PRS 15.56
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CSI 30.15rCSI 66.74%PRS 16.45
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CSI 26.45rCSI 20.8%PRS 21.44
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CSI 23.96rCSI 19.38%PRS 17.77
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CSI 22.87rCSI 23.96%PRS 16.56
-
CSI 22.43rCSI 19.34%PRS 27.94
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CSI 22.42rCSI 61.59%PRS 29.15
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CSI 20.55rCSI 59.49%PRS 20.06
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CSI 19.56rCSI 16.4%PRS 21.2
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CSI 18.38rCSI 16.6%PRS 15.97
-
CSI 18.15rCSI 15.71%PRS 19.99
-
CSI 17.61rCSI 34.24%PRS 18.16
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CSI 16.46rCSI 20.66%PRS 23
-
CSI 15.02rCSI 17.64%PRS 20.67
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CSI 13.95rCSI 20.11%PRS 28.12
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CSI 13.05rCSI 60.84%PRS 40.01
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CSI 12.27rCSI 48.82%PRS 30.68
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CSI 12.21rCSI 23.31%PRS 39.33
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CSI 11.82rCSI 9.6%PRS 18.76
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CSI 11.78rCSI 30.59%PRS 22.92
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CSI 11.58rCSI 16.61%PRS 13.71
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CSI 11.51rCSI 66.99%PRS 26.47
-
CSI 11.01rCSI 14.72%PRS 23.28
-
CSI 11rCSI 7.31%PRS 21.36
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CSI 10.62rCSI 14.52%PRS 20.11
-
CSI 10.59rCSI 13.48%PRS 20.64
-
CSI 9.66rCSI 6.72%PRS 21.14
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CSI 9.52rCSI 7.62%PRS 31.78
-
CSI 9.47rCSI 15.25%PRS 13.6
-
CSI 9.4rCSI 22.35%PRS 26.6
-
CSI 9.38rCSI 27.03%PRS 33.37
-
CSI 9.34rCSI 21.29%PRS 18.35
-
CSI 8.9rCSI 28.57%PRS 25.57
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CSI 8.57rCSI 13.18%PRS 24.51
-
CSI 8.44rCSI 45.93%PRS 41.72
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CSI 8.42rCSI 12.35%PRS 23.28
-
CSI 8.21rCSI 23.1%PRS 24.03
-
CSI 8.01rCSI 11.35%PRS 16.49
-
CSI 7.86rCSI 11.61%PRS 27.73
-
CSI 7.45rCSI 81.6%PRS 31.66
-
CSI 7.16rCSI 7.03%PRS 27.81
-
CSI 7.08rCSI 10.94%PRS 16.62
-
CSI 7.03rCSI 9.35%PRS 19.44
-
CSI 6.92rCSI 10.15%PRS 66.22
-
CSI 6.89rCSI 24.16%PRS 31.21
-
CSI 6.78rCSI 8.88%PRS 63.67
-
CSI 6.74rCSI 12.99%PRS 39.6
-
CSI 6.53rCSI 14.92%PRS 17.25
-
CSI 6.39rCSI 8.88%PRS 18.2
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CSI 6.22rCSI 4.73%PRS 23.42
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CSI 6.18rCSI 8.56%PRS 25.27
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CSI 6.17rCSI 9.74%PRS 17.85
-
CSI 6.11rCSI 6.25%PRS 32.85
-
CSI 6.02rCSI 7.73%PRS 20.5
-
CSI 5.99rCSI 58.9%PRS 47.15
-
CSI 5.97rCSI 6.23%PRS 18.19
-
CSI 5.97rCSI 44.84%PRS 32.27
-
CSI 5.94rCSI 7.94%PRS 33.73
-
CSI 5.91rCSI 5.5%PRS 17.8
-
CSI 5.81rCSI 9.24%PRS 22.89
-
CSI 5.78rCSI 13.86%PRS 31.67
-
CSI 5.69rCSI 13.58%PRS 27.15
-
CSI 5.63rCSI 8.73%PRS 26.61
-
CSI 5.58rCSI 3.72%PRS 43.77
-
CSI 5.54rCSI 6.23%PRS 28.51
-
CSI 5.53rCSI 20%PRS 30.45
-
CSI 5.28rCSI 15.59%PRS 21.41
-
CSI 5.27rCSI 7.18%PRS 41.72
-
CSI 5.22rCSI 8.37%PRS 49.86
-
CSI 5.22rCSI 6.03%PRS 13.04
-
CSI 5.14rCSI 6.74%PRS 25.26
-
CSI 5.14rCSI 4.72%PRS 20.73
-
CSI 5.12rCSI 8.86%PRS 13.53
-
CSI 4.91rCSI 8.09%PRS 20.97
-
CSI 4.9rCSI 2.89%PRS 24.68
-
CSI 4.88rCSI 10.12%PRS 17.69
-
CSI 4.83rCSI 4.46%PRS 18.35
-
CSI 4.82rCSI 8.23%PRS 35.74
-
CSI 4.81rCSI 52.35%PRS 33.76
-
CSI 4.77rCSI 7.06%PRS 20.3
-
CSI 4.72rCSI 3.53%PRS 28.4
-
CSI 4.72rCSI 24.37%PRS 34.47
-
CSI 4.66rCSI 3.24%PRS 25.25
-
CSI 4.62rCSI 9.16%PRS 48.49
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CSI 4.46rCSI 3.3%PRS 15.53
-
CSI 4.44rCSI 31.31%PRS 49.86
-
CSI 4.28rCSI 4.9%PRS 36.02
-
CSI 4.18rCSI 3.24%PRS 16.99
-
CSI 4.11rCSI 3.24%PRS 12.16
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CSI 4.06rCSI 27.89%PRS 34.3
-
CSI 4.03rCSI 10.63%PRS 21.19
-
CSI 4.03rCSI 10.19%PRS 21.96
-
CSI 3.83rCSI 3.17%PRS 17.98
-
CSI -4.4rCSI -8.0%PRS 44.2%
-
CSI 0.2rCSI 3.2%PRS 50.3%
-
CSI 0.2rCSI 1.1%PRS 26.1%
-
CSI 0.2rCSI 1.8%PRS 63.7%
-
CSI 0.2rCSI 4.8%PRS 50.5%
-
CSI 0.2rCSI 4.8%PRS 82.9%
-
CSI 0.2rCSI 4.9%PRS 83.3%
-
CSI 0.2rCSI 1.7%PRS 18.0%
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CSI 0.3rCSI 2.7%PRS 54.2%
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CSI 0.3rCSI 0.5%PRS 20.3%
-
CSI 0.3rCSI 1.0%PRS 60.9%
-
CSI 0.3rCSI 0.5%PRS 16.4%
-
CSI 0.3rCSI 4.4%PRS 52.8%
-
CSI 0.3rCSI 1.6%PRS 24.0%
-
CSI 0.4rCSI 5.9%PRS 68.1%
-
CSI 0.4rCSI 3.2%PRS 69.1%
-
CSI 0.4rCSI 8.8%PRS 53.5%
-
CSI 0.4rCSI 0.5%PRS 31.0%
-
CSI 0.5rCSI 1.5%PRS 18.5%
-
CSI 0.5rCSI 2.5%PRS 56.0%
-
CSI 0.5rCSI 0.7%PRS 24.6%
-
CSI 0.5rCSI 3.9%PRS 36.4%
-
CSI 0.5rCSI 2.8%PRS 31.6%
-
CSI 0.5rCSI 0.8%PRS 17.9%
-
CSI 0.5rCSI 0.5%PRS 22.2%
-
CSI 0.5rCSI 13.2%PRS 80.2%
-
CSI 0.5rCSI 1.5%PRS 14.7%
-
CSI 0.6rCSI 2.1%PRS 35.3%
-
CSI 0.6rCSI 1.5%PRS 16.5%
-
CSI 0.6rCSI 0.9%PRS 41.2%
-
CSI 0.6rCSI 2.7%PRS 56.7%
-
CSI 0.6rCSI 2.8%PRS 17.3%
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CSI 0.6rCSI 2.7%PRS 31.2%
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CSI 0.7rCSI 1.7%PRS 13.4%
-
CSI 0.7rCSI 1.6%PRS 20.6%
-
CSI 0.7rCSI 3.1%PRS 67.8%
-
CSI 0.7rCSI 3.2%PRS 32.9%
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CSI 0.7rCSI 1.2%PRS 19.4%
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CSI 0.7rCSI 4.9%PRS 44.6%
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CSI 0.7rCSI 3.3%PRS 16.9%
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CSI 0.8rCSI 4.2%PRS 59.5%
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CSI 0.8rCSI 3.5%PRS 32.9%
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CSI 0.8rCSI 1.8%PRS 20.0%
-
CSI 0.8rCSI 3.9%PRS 44.6%
-
CSI 0.8rCSI 1.2%PRS 18.8%
-
CSI 0.8rCSI 2.4%PRS 31.2%
-
CSI 0.9rCSI 1.3%PRS 21.2%
-
CSI 0.9rCSI 1.4%PRS 15.0%
-
CSI 0.9rCSI 1.7%PRS 22.4%
-
CSI 0.9rCSI 1.9%PRS 28.2%
-
CSI 0.9rCSI 11.0%PRS 60.7%
-
CSI 1.0rCSI 2.3%PRS 28.1%
-
CSI 1.0rCSI 2.1%PRS 34.8%
-
CSI 1.0rCSI 1.5%PRS 31.3%
-
CSI 1.0rCSI 1.8%PRS 14.7%
-
CSI 1.0rCSI 1.4%PRS 28.0%
-
CSI 1.0rCSI 0.8%PRS 31.5%
-
CSI 1.0rCSI 18.0%PRS 61.7%
-
CSI 1.1rCSI 5.1%PRS 21.8%
-
CSI 1.1rCSI 1.5%PRS 17.6%
-
CSI 1.1rCSI 7.2%PRS 52.6%
-
CSI 1.1rCSI 9.0%PRS 61.1%
-
CSI 1.2rCSI 0.9%PRS 30.0%
-
CSI 1.2rCSI 2.4%PRS 18.8%
-
CSI 1.2rCSI 4.5%PRS 15.0%
-
CSI 1.2rCSI 4.2%PRS 57.5%
-
CSI 1.2rCSI 1.5%PRS 27.4%
-
CSI 1.3rCSI 3.6%PRS 38.0%
-
CSI 1.3rCSI 3.6%PRS 27.5%
-
CSI 1.3rCSI 1.5%PRS 25.9%
-
CSI 1.3rCSI 3.6%PRS 30.5%
-
CSI 1.3rCSI 4.1%PRS 11.2%
-
CSI 1.3rCSI 5.1%PRS 17.4%
-
CSI 1.3rCSI 1.3%PRS 15.2%
-
CSI 1.4rCSI 2.6%PRS 12.8%
-
CSI 1.4rCSI 1.7%PRS 18.8%
-
CSI 1.4rCSI 1.9%PRS 26.8%
-
CSI 1.4rCSI 3.4%PRS 26.3%
-
CSI 1.5rCSI 9.0%PRS 58.1%
-
CSI 1.5rCSI 2.6%PRS 10.4%
-
CSI 1.5rCSI 8.2%PRS 45.8%
-
CSI 1.5rCSI 33.9%PRS 63.8%
-
CSI 1.5rCSI 6.3%PRS 43.4%
-
CSI 1.5rCSI 4.2%PRS 62.2%
-
CSI 1.5rCSI 6.1%PRS 37.6%
-
CSI 1.5rCSI 1.2%PRS 18.8%
-
CSI 1.6rCSI 1.9%PRS 21.2%
-
CSI 1.6rCSI 2.5%PRS 15.2%
-
CSI 1.6rCSI 3.5%PRS 27.0%
-
CSI 1.6rCSI 1.2%PRS 26.3%
-
CSI 1.6rCSI 2.0%PRS 51.5%
-
CSI 1.6rCSI 3.7%PRS 24.4%
-
CSI 1.6rCSI 8.4%PRS 60.5%
-
CSI 1.7rCSI 5.9%PRS 28.8%
-
CSI 1.7rCSI 3.4%PRS 13.1%
-
CSI 1.7rCSI 6.1%PRS 52.8%
-
CSI 1.7rCSI 1.9%PRS 20.1%
-
CSI 1.7rCSI 2.0%PRS 48.9%
-
CSI 1.7rCSI 2.4%PRS 35.8%
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CSI 1.7rCSI 6.8%PRS 29.2%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1523901612
Symbol: ARAID_HUMAN
Name: All-trans retinoic acid-induced differentiation factor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10948432
Title: Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes.
PubMed ID: 10948432
DOI: 10.2144/00292st06
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 17524364
Title: Apoptosis related protein 3, an ATRA-upregulated membrane protein arrests the cell cycle at G1/S phase by decreasing the expression of cyclin D1.
PubMed ID: 17524364
PubMed ID: 17387583
Title: Identification of the distinct promoters for the two transcripts of apoptosis related protein 3 and their transcriptional regulation by NFAT and NFkappaB.
PubMed ID: 17387583
PubMed ID: 21723284
Title: NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation.
PubMed ID: 21723284
PubMed ID: 29745899
Title: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates.
PubMed ID: 29745899
DOI: 10.7554/elife.36620
Sequence Information:
- Length: 229
- Mass: 24747
- Checksum: CF051C5E886BCFF1
- Sequence:
MAPHDPGSLT TLVPWAAALL LALGVERALA LPEICTQCPG SVQNLSKVAF YCKTTRELML HARCCLNQKG TILGLDLQNC SLEDPGPNFH QAHTTVIIDL QANPLKGDLA NTFRGFTQLQ TLILPQHVNC PGGINAWNTI TSYIDNQICQ GQKNLCNNTG DPEMCPENGS CVPDGPGLLQ CVCADGFHGY KCMRQGSFSL LMFFGILGAT TLSVSILLWA TQRRKAKTS