Details for: COMMD10
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 362.5312
Cell Significance Index: -56.3900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 215.9331
Cell Significance Index: -54.7700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 138.0273
Cell Significance Index: -56.8600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 124.7769
Cell Significance Index: -58.9100 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 120.9086
Cell Significance Index: -49.1200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 107.0987
Cell Significance Index: -55.0900 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 51.5113
Cell Significance Index: -49.1800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 47.6416
Cell Significance Index: -58.7400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 19.5382
Cell Significance Index: -52.3400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 16.2296
Cell Significance Index: -35.5200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 15.0024
Cell Significance Index: -59.2000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 3.6441
Cell Significance Index: 93.6700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 3.3918
Cell Significance Index: 260.2900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 3.2856
Cell Significance Index: 184.3700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.1551
Cell Significance Index: 427.6900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.9438
Cell Significance Index: 316.1400 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.9158
Cell Significance Index: 37.3900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.6729
Cell Significance Index: 44.6700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.6481
Cell Significance Index: 330.6000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.4571
Cell Significance Index: 40.7200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.3013
Cell Significance Index: 466.7500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1871
Cell Significance Index: 129.1200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.1855
Cell Significance Index: 17.0500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.9927
Cell Significance Index: 686.5900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.9369
Cell Significance Index: 22.8600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.8379
Cell Significance Index: 17.9100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.5541
Cell Significance Index: 8.1800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4845
Cell Significance Index: 22.5900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.4833
Cell Significance Index: 32.5000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4811
Cell Significance Index: 21.2800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4592
Cell Significance Index: 250.7700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4460
Cell Significance Index: 30.8500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.4157
Cell Significance Index: 15.7400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3338
Cell Significance Index: 60.1700 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.3213
Cell Significance Index: 2.6200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3180
Cell Significance Index: 39.1000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2797
Cell Significance Index: 177.6500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.2742
Cell Significance Index: 516.2800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.2498
Cell Significance Index: 11.7400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.2474
Cell Significance Index: 6.6300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2111
Cell Significance Index: 324.9600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2099
Cell Significance Index: 95.2700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1943
Cell Significance Index: 358.3900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.1866
Cell Significance Index: 11.4700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1789
Cell Significance Index: 8.1100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1585
Cell Significance Index: 18.6900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1274
Cell Significance Index: 17.4900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1096
Cell Significance Index: 48.4500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0561
Cell Significance Index: 76.2900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0445
Cell Significance Index: 0.5300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0247
Cell Significance Index: 2.4400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0346
Cell Significance Index: -5.0300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0408
Cell Significance Index: -29.9200 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.0474
Cell Significance Index: -0.6800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0531
Cell Significance Index: -40.2100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0639
Cell Significance Index: -47.3500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0916
Cell Significance Index: -1.5700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0916
Cell Significance Index: -11.8400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0952
Cell Significance Index: -16.2600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0980
Cell Significance Index: -10.0100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0990
Cell Significance Index: -55.8400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1047
Cell Significance Index: -65.3600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.1251
Cell Significance Index: -23.8100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1586
Cell Significance Index: -20.3300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1675
Cell Significance Index: -12.4800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1803
Cell Significance Index: -51.8700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2242
Cell Significance Index: -26.1300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2242
Cell Significance Index: -14.1300 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.2518
Cell Significance Index: -2.2400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2914
Cell Significance Index: -33.3800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2971
Cell Significance Index: -62.5800 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.2980
Cell Significance Index: -5.0200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3024
Cell Significance Index: -15.7100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.3160
Cell Significance Index: -6.7300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3214
Cell Significance Index: -11.1700 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.3492
Cell Significance Index: -2.1100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3800
Cell Significance Index: -39.5700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4976
Cell Significance Index: -35.1900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5425
Cell Significance Index: -35.0000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.5430
Cell Significance Index: -28.5100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5783
Cell Significance Index: -45.8000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.6430
Cell Significance Index: -18.3500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.6580
Cell Significance Index: -15.7800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6622
Cell Significance Index: -21.2100 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.6890
Cell Significance Index: -10.1700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.7121
Cell Significance Index: -37.0900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.7134
Cell Significance Index: -11.9400 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: -0.7464
Cell Significance Index: -7.5300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.7771
Cell Significance Index: -20.4400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.8118
Cell Significance Index: -49.7700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.8580
Cell Significance Index: -23.3600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.9046
Cell Significance Index: -8.3300 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.9525
Cell Significance Index: -9.8600 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.9557
Cell Significance Index: -15.4200 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.9647
Cell Significance Index: -12.0300 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: -1.0263
Cell Significance Index: -10.6300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -1.0340
Cell Significance Index: -12.8300 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -1.0809
Cell Significance Index: -54.6300 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -1.0919
Cell Significance Index: -13.7500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.1092
Cell Significance Index: -35.3300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2932847035
Symbol: COMDA_HUMAN
Name: COMM domain-containing protein 10
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15799966
Title: COMMD proteins, a novel family of structural and functional homologs of MURR1.
PubMed ID: 15799966
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21778237
Title: COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.
PubMed ID: 21778237
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23637203
Title: Functional interaction of COMMD3 and COMMD9 with the epithelial sodium channel.
PubMed ID: 23637203
PubMed ID: 23563313
Title: CCDC22 deficiency in humans blunts activation of proinflammatory NF-kappaB signaling.
PubMed ID: 23563313
DOI: 10.1172/jci66466
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25355947
Title: COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.
PubMed ID: 25355947
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 202
- Mass: 22966
- Checksum: 4D3C014FE59188CB
- Sequence:
MAVPAALILR ESPSMKKAVS LINAIDTGRF PRLLTRILQK LHLKAESSFS EEEEEKLQAA FSLEKQDLHL VLETISFILE QAVYHNVKPA ALQQQLENIH LRQDKAEAFV NTWSSMGQET VEKFRQRILA PCKLETVGWQ LNLQMAHSAQ AKLKSPQAVL QLGVNNEDSK SLEKVLVEFS HKELFDFYNK LETIQAQLDS LT
Genular Protein ID: 187400790
Symbol: D6RJ90_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 188
- Mass: 21530
- Checksum: 469DD968A64C8A70
- Sequence:
MKKAVSLINA IDTGRFPRLL TRILQKLHLK AESSFSEEEE EKLQAAFSLE KQDLHLVLET ISFILEQAVY HNVKPAALQQ QLENIHLRQD KAEAFVNTWS SMGQETVEKF RQRILAPCKL ETVGWQLNLQ MAHSAQAKLK SPQAVLQLGV NNEDSKSLEK VLVEFSHKEL FDFYNKLETI QAQLDSLT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.