Details for: HDAC7

Gene ID: 51564

Symbol: HDAC7

Ensembl ID: ENSG00000061273

Description: histone deacetylase 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 206.2423
    Cell Significance Index: -32.0800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 119.5379
    Cell Significance Index: -30.3200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 72.6930
    Cell Significance Index: -34.3200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 72.0972
    Cell Significance Index: -29.2900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 64.4264
    Cell Significance Index: -33.1400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 30.7727
    Cell Significance Index: -29.3800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.2354
    Cell Significance Index: -33.5800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.2888
    Cell Significance Index: -32.9200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.1402
    Cell Significance Index: -26.5700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.6143
    Cell Significance Index: -29.5300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.6517
    Cell Significance Index: -34.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.5921
    Cell Significance Index: 135.0200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.9548
    Cell Significance Index: 26.6700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.3820
    Cell Significance Index: 161.0600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.1877
    Cell Significance Index: 23.1800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.0669
    Cell Significance Index: 125.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0400
    Cell Significance Index: 79.8100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.0179
    Cell Significance Index: 14.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9286
    Cell Significance Index: 91.8600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8935
    Cell Significance Index: 24.3200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8770
    Cell Significance Index: 175.9300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8255
    Cell Significance Index: 745.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6905
    Cell Significance Index: 94.8300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5346
    Cell Significance Index: 106.1000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4972
    Cell Significance Index: 61.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4906
    Cell Significance Index: 267.9400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4846
    Cell Significance Index: 78.8200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4590
    Cell Significance Index: 82.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4139
    Cell Significance Index: 19.4600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.4109
    Cell Significance Index: 20.7700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4031
    Cell Significance Index: 144.5900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3709
    Cell Significance Index: 40.3400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2743
    Cell Significance Index: 17.7000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2645
    Cell Significance Index: 407.2600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2443
    Cell Significance Index: 108.0000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2413
    Cell Significance Index: 166.9000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2200
    Cell Significance Index: 405.8000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.2168
    Cell Significance Index: 1.3100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2050
    Cell Significance Index: 39.0200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.1884
    Cell Significance Index: 2.1400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.1518
    Cell Significance Index: 94.7800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1381
    Cell Significance Index: 17.7100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1273
    Cell Significance Index: 7.6400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1267
    Cell Significance Index: 6.5800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0937
    Cell Significance Index: 2.0000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0921
    Cell Significance Index: 6.3700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0877
    Cell Significance Index: 2.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0817
    Cell Significance Index: 51.8900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0546
    Cell Significance Index: 102.8900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0525
    Cell Significance Index: 71.3600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0369
    Cell Significance Index: 4.7700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0339
    Cell Significance Index: 2.4000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0326
    Cell Significance Index: 14.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0187
    Cell Significance Index: 0.5400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0132
    Cell Significance Index: 2.2600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0095
    Cell Significance Index: 0.2100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0012
    Cell Significance Index: -0.0700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0193
    Cell Significance Index: -14.5800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0212
    Cell Significance Index: -15.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0230
    Cell Significance Index: -0.6600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0307
    Cell Significance Index: -2.2900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0318
    Cell Significance Index: -4.6200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0359
    Cell Significance Index: -26.3400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0418
    Cell Significance Index: -23.5600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0491
    Cell Significance Index: -0.8200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0600
    Cell Significance Index: -2.1100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0649
    Cell Significance Index: -3.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0660
    Cell Significance Index: -2.9900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0721
    Cell Significance Index: -7.3700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1023
    Cell Significance Index: -29.4400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1125
    Cell Significance Index: -23.7000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1243
    Cell Significance Index: -14.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1420
    Cell Significance Index: -7.9700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2013
    Cell Significance Index: -22.9800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2043
    Cell Significance Index: -4.7200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2128
    Cell Significance Index: -22.1600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2170
    Cell Significance Index: -14.5900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2303
    Cell Significance Index: -3.4000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2525
    Cell Significance Index: -8.7800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2613
    Cell Significance Index: -13.7200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2618
    Cell Significance Index: -3.7600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2830
    Cell Significance Index: -8.3100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2864
    Cell Significance Index: -12.6700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3742
    Cell Significance Index: -14.1700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3875
    Cell Significance Index: -9.9000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3944
    Cell Significance Index: -31.2400
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.3977
    Cell Significance Index: -3.5300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.4129
    Cell Significance Index: -8.5700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4247
    Cell Significance Index: -8.8900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4396
    Cell Significance Index: -10.9900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4574
    Cell Significance Index: -14.6500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4635
    Cell Significance Index: -10.1500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4950
    Cell Significance Index: -30.3500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5183
    Cell Significance Index: -14.7900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5283
    Cell Significance Index: -33.3000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.5396
    Cell Significance Index: -8.2000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.5783
    Cell Significance Index: -10.2200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.7061
    Cell Significance Index: -13.0500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.7351
    Cell Significance Index: -19.3300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.7389
    Cell Significance Index: -19.7300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Histone Deacetylase Activity:** HDAC7 possesses histone deacetylase activity, which allows it to remove acetyl groups from histones, leading to chromatin compaction and reduced gene expression. 2. **Multifunctional Protein:** HDAC7 interacts with various proteins, including transcription factors, kinases, and other HDACs, to regulate cellular processes. 3. **Cell-Specific Expression:** HDAC7 is highly expressed in hematopoietic cells, smooth muscle cells, and other cell types, suggesting a specific role in these cell types. 4. **Disease Association:** HDAC7 has been implicated in several diseases, including cancer, autoimmune disorders, and metabolic disorders. **Pathways and Functions:** 1. **Notch Signaling:** HDAC7 is a key regulator of Notch signaling, a critical pathway involved in cell fate decisions, differentiation, and proliferation. 2. **Chromatin Remodeling:** HDAC7 participates in chromatin remodeling, a process that reorganizes chromatin structure to regulate gene expression. 3. **Transcriptional Regulation:** HDAC7 modulates transcriptional activity by removing acetyl groups from histones, which in turn affects the recruitment of transcriptional machinery. 4. **Cell Signaling:** HDAC7 interacts with various signaling pathways, including the PI3K/AKT pathway, to regulate cellular responses to growth factors and stress. 5. **Cell Migration and Angiogenesis:** HDAC7 is involved in regulating cell migration and angiogenesis, processes critical for tissue development and cancer progression. **Clinical Significance:** 1. **Cancer:** HDAC7 has been implicated in cancer development and progression, particularly in hematological malignancies and solid tumors. 2. **Autoimmune Disorders:** HDAC7 has been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where its dysregulation contributes to immune dysfunction. 3. **Metabolic Disorders:** HDAC7 has been associated with metabolic disorders, including obesity and type 2 diabetes, where its dysregulation affects glucose metabolism and insulin signaling. 4. **Therapeutic Target:** HDAC7 has emerged as a potential therapeutic target for cancer treatment, as its inhibition has shown promise in preclinical models. In conclusion, HDAC7 is a multifaceted regulator of gene expression and cellular processes, involved in various signaling pathways, chromatin remodeling, and transcriptional regulation. Its dysregulation has been implicated in several diseases, making it a promising therapeutic target for cancer and other diseases.

Genular Protein ID: 2838107570

Symbol: HDAC7_HUMAN

Name: Histone deacetylase 7

UniProtKB Accession Codes:

Q8WUI4 B3KY08 B4DWI0 B4E0Q5 Q6P1W9 Q6W9G7 Q7Z4K2 Q7Z5I1 Q96K01 Q9BR73 Q9H7L0 Q9NW41 Q9NWA9 Q9NYK9 Q9UFU7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 13 DrugCentral 1 EC 1 EMBL 19 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 10 Pumba 1 RNAct 1 Reactome 6 RefSeq 5 Rhea 7 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 11262386

Title: Tip60 and HDAC7 interact with the endothelin receptor a and may be involved in downstream signaling.

PubMed ID: 11262386

DOI: 10.1074/jbc.c000909200

PubMed ID: 11466315

Title: Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.

PubMed ID: 11466315

DOI: 10.1074/jbc.m104935200

PubMed ID: 12239305

Title: Signal transduction and transcription factor modification during reactivation of Epstein-Barr virus from latency.

PubMed ID: 12239305

DOI: 10.1128/jvi.76.20.10290-10298.2002

PubMed ID: 12551922

Title: Tip60 is a co-repressor for STAT3.

PubMed ID: 12551922

DOI: 10.1074/jbc.m210816200

PubMed ID: 16980613

Title: New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases.

PubMed ID: 16980613

DOI: 10.1128/mcb.00231-06

PubMed ID: 17962809

Title: Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2.

PubMed ID: 17962809

DOI: 10.1038/sj.emboj.7601891

PubMed ID: 17373667

Title: Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases.

PubMed ID: 17373667

DOI: 10.1002/ijc.22673

PubMed ID: 17360565

Title: FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression.

PubMed ID: 17360565

DOI: 10.1073/pnas.0700298104

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20188095

Title: Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases.

PubMed ID: 20188095

DOI: 10.1016/j.febslet.2010.02.057

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22155184

Title: Beta-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.

PubMed ID: 22155184

DOI: 10.1053/j.gastro.2011.11.041

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28167758

Title: MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases.

PubMed ID: 28167758

DOI: 10.1073/pnas.1621425114

PubMed ID: 37369679

Title: K235 acetylation couples with PSPC1 to regulate the m6A demethylation activity of ALKBH5 and tumorigenesis.

PubMed ID: 37369679

DOI: 10.1038/s41467-023-39414-4

PubMed ID: 18285338

Title: Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.

PubMed ID: 18285338

DOI: 10.1074/jbc.m707362200

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 952
  • Mass: 102927
  • Checksum: 786785B084667731
  • Sequence:
    • MDLRVGQRPP VEPPPEPTLL ALQRPQRLHH HLFLAGLQQQ RSVEPMRLSM DTPMPELQVG 
PQEQELRQLL HKDKSKRSAV ASSVVKQKLA EVILKKQQAA LERTVHPNSP GIPYRTLEPL 
ETEGATRSML SSFLPPVPSL PSDPPEHFPL RKTVSEPNLK LRYKPKKSLE RRKNPLLRKE 
SAPPSLRRRP AETLGDSSPS SSSTPASGCS SPNDSEHGPN PILGSEALLG QRLRLQETSV 
APFALPTVSL LPAITLGLPA PARADSDRRT HPTLGPRGPI LGSPHTPLFL PHGLEPEAGG 
TLPSRLQPIL LLDPSGSHAP LLTVPGLGPL PFHFAQSLMT TERLSGSGLH WPLSRTRSEP 
LPPSATAPPP PGPMQPRLEQ LKTHVQVIKR SAKPSEKPRL RQIPSAEDLE TDGGGPGQVV 
DDGLEHRELG HGQPEARGPA PLQQHPQVLL WEQQRLAGRL PRGSTGDTVL LPLAQGGHRP 
LSRAQSSPAA PASLSAPEPA SQARVLSSSE TPARTLPFTT GLIYDSVMLK HQCSCGDNSR 
HPEHAGRIQS IWSRLQERGL RSQCECLRGR KASLEELQSV HSERHVLLYG TNPLSRLKLD 
NGKLAGLLAQ RMFVMLPCGG VGVDTDTIWN ELHSSNAARW AAGSVTDLAF KVASRELKNG 
FAVVRPPGHH ADHSTAMGFC FFNSVAIACR QLQQQSKASK ILIVDWDVHH GNGTQQTFYQ 
DPSVLYISLH RHDDGNFFPG SGAVDEVGAG SGEGFNVNVA WAGGLDPPMG DPEYLAAFRI 
VVMPIAREFS PDLVLVSAGF DAAEGHPAPL GGYHVSAKCF GYMTQQLMNL AGGAVVLALE 
GGHDLTAICD ASEACVAALL GNRVDPLSEE GWKQKPNLNA IRSLEAVIRV HSKYWGCMQR 
LASCPDSWVP RVPGADKEEV EAVTALASLS VGILAEDRPS EQLVEEEEPM NL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.