Details for: MED15

Gene ID: 51586

Symbol: MED15

Ensembl ID: ENSG00000099917

Description: mediator complex subunit 15

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 235.6871
    Cell Significance Index: -36.6600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 142.1287
    Cell Significance Index: -36.0500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 86.0293
    Cell Significance Index: -34.9500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 82.7327
    Cell Significance Index: -39.0600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 74.8466
    Cell Significance Index: -38.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 36.7743
    Cell Significance Index: -35.1100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 30.8608
    Cell Significance Index: -38.0500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.3284
    Cell Significance Index: -35.7100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 12.0529
    Cell Significance Index: -37.0200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.7642
    Cell Significance Index: -38.5300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.1292
    Cell Significance Index: -19.9800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.8049
    Cell Significance Index: 74.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.8969
    Cell Significance Index: 131.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.8042
    Cell Significance Index: 293.4300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5683
    Cell Significance Index: 314.6000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.4253
    Cell Significance Index: 41.0700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.2678
    Cell Significance Index: 27.4700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1838
    Cell Significance Index: 424.6000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0823
    Cell Significance Index: 214.7800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.0628
    Cell Significance Index: 28.4800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0545
    Cell Significance Index: 29.4700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0082
    Cell Significance Index: 109.6700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8787
    Cell Significance Index: 39.8300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.8131
    Cell Significance Index: 20.3300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7686
    Cell Significance Index: 46.1400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.6440
    Cell Significance Index: 28.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6300
    Cell Significance Index: 48.3500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.6267
    Cell Significance Index: 23.7300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5585
    Cell Significance Index: 31.3400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4939
    Cell Significance Index: 60.7400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.4920
    Cell Significance Index: 25.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4627
    Cell Significance Index: 83.4200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3763
    Cell Significance Index: 19.5500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3670
    Cell Significance Index: 36.3000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3536
    Cell Significance Index: 319.2400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.2926
    Cell Significance Index: 5.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2719
    Cell Significance Index: 16.7200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2620
    Cell Significance Index: 9.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2613
    Cell Significance Index: 16.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2452
    Cell Significance Index: 133.9200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.2338
    Cell Significance Index: 15.7200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2266
    Cell Significance Index: 10.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2232
    Cell Significance Index: 30.6500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1882
    Cell Significance Index: 354.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1731
    Cell Significance Index: 76.5100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1683
    Cell Significance Index: 259.0300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1484
    Cell Significance Index: 3.1700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1411
    Cell Significance Index: 16.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1356
    Cell Significance Index: 3.6900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1343
    Cell Significance Index: 3.8500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1275
    Cell Significance Index: 2.7200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1214
    Cell Significance Index: 223.8700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1166
    Cell Significance Index: 158.4900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1039
    Cell Significance Index: 3.0500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0694
    Cell Significance Index: 8.9700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0673
    Cell Significance Index: 12.8000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0661
    Cell Significance Index: 45.7200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0648
    Cell Significance Index: 1.1100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0538
    Cell Significance Index: 34.2000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0507
    Cell Significance Index: 0.7600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0470
    Cell Significance Index: 1.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0462
    Cell Significance Index: 20.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0337
    Cell Significance Index: 2.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0112
    Cell Significance Index: 0.5200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0173
    Cell Significance Index: -0.2200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0217
    Cell Significance Index: -3.7100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0332
    Cell Significance Index: -25.1600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0390
    Cell Significance Index: -28.6100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0402
    Cell Significance Index: -29.7800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0463
    Cell Significance Index: -0.2800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0467
    Cell Significance Index: -1.2000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0566
    Cell Significance Index: -7.2600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0581
    Cell Significance Index: -5.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0636
    Cell Significance Index: -35.8500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0673
    Cell Significance Index: -42.0200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1099
    Cell Significance Index: -1.5800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1189
    Cell Significance Index: -34.2200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1299
    Cell Significance Index: -15.1400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1301
    Cell Significance Index: -18.9100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1767
    Cell Significance Index: -3.8700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1796
    Cell Significance Index: -2.4500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1963
    Cell Significance Index: -41.3400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2248
    Cell Significance Index: -2.0700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2285
    Cell Significance Index: -5.4800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2392
    Cell Significance Index: -27.4000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2409
    Cell Significance Index: -25.0800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2705
    Cell Significance Index: -19.1300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2912
    Cell Significance Index: -15.2900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2974
    Cell Significance Index: -7.8200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3078
    Cell Significance Index: -7.5100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3474
    Cell Significance Index: -6.4200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3669
    Cell Significance Index: -23.1300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4501
    Cell Significance Index: -35.6500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4836
    Cell Significance Index: -6.9300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5334
    Cell Significance Index: -32.7000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5355
    Cell Significance Index: -17.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5473
    Cell Significance Index: -9.1600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5640
    Cell Significance Index: -19.6000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.5663
    Cell Significance Index: -8.3600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5843
    Cell Significance Index: -15.6300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MED15 is a member of the mediator complex, a protein complex that regulates transcriptional elongation by RNA polymerase II. The mediator complex is composed of multiple subunits, each with distinct functions, and is involved in the regulation of gene expression in response to various stimuli. MED15 is a key component of the mediator complex, interacting with RNA polymerase II to facilitate transcriptional elongation. The gene is highly expressed in hematopoietic cells, epithelial cells, and immune cells, suggesting its importance in these cell types. **Pathways and Functions:** The MED15 gene is involved in several key biological pathways, including: 1. **Adipogenesis:** MED15 regulates the expression of genes involved in adipogenesis, the process of fat cell differentiation. Abnormal expression of MED15 has been linked to obesity and metabolic disorders. 2. **Core Mediator Complex:** MED15 is a key component of the mediator complex, which regulates transcriptional elongation by RNA polymerase II. This complex is involved in the regulation of gene expression in response to various stimuli. 3. **Gene Expression (Transcription):** MED15 regulates gene expression by interacting with RNA polymerase II to facilitate transcriptional elongation. 4. **Infectious Disease:** MED15 is involved in the regulation of gene expression in response to viral infections, including respiratory syncytial virus. 5. **Lipid Metabolism:** MED15 regulates the expression of genes involved in lipid metabolism, including PPARα, a transcription factor involved in lipid metabolism. **Clinical Significance:** Abnormal expression of MED15 has been linked to various diseases, including: 1. **Obesity and Metabolic Disorders:** MED15 regulates adipogenesis, and abnormal expression of MED15 has been linked to obesity and metabolic disorders. 2. **Immune Disorders:** MED15 is involved in the regulation of gene expression in immune cells, and abnormal expression of MED15 has been linked to immune disorders, including autoimmune diseases. 3. **Cancer:** MED15 is involved in the regulation of gene expression in cancer cells, and abnormal expression of MED15 has been linked to cancer development. 4. **Neurological Disorders:** MED15 is involved in the regulation of gene expression in neurons, and abnormal expression of MED15 has been linked to neurological disorders, including Alzheimer's disease. In conclusion, the MED15 gene plays a critical role in regulating gene expression through its involvement in the mediator complex. Abnormal expression of MED15 has been linked to various diseases, highlighting the importance of this gene in maintaining cellular homeostasis and preventing disease. Further research is needed to fully understand the mechanisms of MED15 and its implications in human disease.

Genular Protein ID: 1449310646

Symbol: MED15_HUMAN

Name: Mediator of RNA polymerase II transcription subunit 15

UniProtKB Accession Codes:

Q96RN5 D3DX31 D3DX32 O15413 Q6IC31 Q8NF16 Q96CT0 Q96IH7 Q9P1T3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 EMDB 7 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 4 RefSeq 4 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11024300

Title: A novel glutamine-rich putative transcriptional adaptor protein (TIG-1), preferentially expressed in placental and bone-marrow tissues.

PubMed ID: 11024300

DOI: 10.1016/s0378-1119(00)00292-4

PubMed ID: 11414760

Title: Isolation and characterization of a novel gene from the DiGeorge chromosomal region that encodes for a mediator subunit.

PubMed ID: 11414760

DOI: 10.1006/geno.2001.6566

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9225980

Title: cDNAs with long CAG trinucleotide repeats from human brain.

PubMed ID: 9225980

DOI: 10.1007/s004390050476

PubMed ID: 10235267

Title: Composite co-activator ARC mediates chromatin-directed transcriptional activation.

PubMed ID: 10235267

DOI: 10.1038/19789

PubMed ID: 12167862

Title: A component of the ARC/Mediator complex required for TGF beta/Nodal signalling.

PubMed ID: 12167862

DOI: 10.1038/nature00969

PubMed ID: 15175163

Title: A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.

PubMed ID: 15175163

DOI: 10.1016/j.molcel.2004.05.006

PubMed ID: 15989967

Title: MED1/TRAP220 exists predominantly in a TRAP/Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.

PubMed ID: 15989967

DOI: 10.1016/j.molcel.2005.05.015

PubMed ID: 16904669

Title: TRIM11 binds to and destabilizes a key component of the activator-mediated cofactor complex (ARC105) through the ubiquitin-proteasome system.

PubMed ID: 16904669

DOI: 10.1016/j.febslet.2006.07.066

PubMed ID: 16630888

Title: Genome-wide location of the coactivator mediator: binding without activation and transient Cdk8 interaction on DNA.

PubMed ID: 16630888

DOI: 10.1016/j.molcel.2006.03.023

PubMed ID: 18568018

Title: TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.

PubMed ID: 18568018

DOI: 10.1038/ncb1748

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16799563

Title: An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

PubMed ID: 16799563

DOI: 10.1038/nature04942

Sequence Information:

  • Length: 788
  • Mass: 86753
  • Checksum: BB6AC6C63ED2F97E
  • Sequence:
    • MDVSGQETDW RSTAFRQKLV SQIEDAMRKA GVAHSKSSKD MESHVFLKAK TRDEYLSLVA 
RLIIHFRDIH NKKSQASVSD PMNALQSLTG GPAAGAAGIG MPPRGPGQSL GGMGSLGAMG 
QPMSLSGQPP PGTSGMAPHS MAVVSTATPQ TQLQLQQVAL QQQQQQQQFQ QQQQAALQQQ 
QQQQQQQQFQ AQQSAMQQQF QAVVQQQQQL QQQQQQQQHL IKLHHQNQQQ IQQQQQQLQR 
IAQLQLQQQQ QQQQQQQQQQ QQALQAQPPI QQPPMQQPQP PPSQALPQQL QQMHHTQHHQ 
PPPQPQQPPV AQNQPSQLPP QSQTQPLVSQ AQALPGQMLY TQPPLKFVRA PMVVQQPPVQ 
PQVQQQQTAV QTAQAAQMVA PGVQMITEAL AQGGMHIRAR FPPTTAVSAI PSSSIPLGRQ 
PMAQVSQSSL PMLSSPSPGQ QVQTPQSMPP PPQPSPQPGQ PSSQPNSNVS SGPAPSPSSF 
LPSPSPQPSQ SPVTARTPQN FSVPSPGPLN TPVNPSSVMS PAGSSQAEEQ QYLDKLKQLS 
KYIEPLRRMI NKIDKNEDRK KDLSKMKSLL DILTDPSKRC PLKTLQKCEI ALEKLKNDMA 
VPTPPPPPVP PTKQQYLCQP LLDAVLANIR SPVFNHSLYR TFVPAMTAIH GPPITAPVVC 
TRKRRLEDDE RQSIPSVLQG EVARLDPKFL VNLDPSHCSN NGTVHLICKL DDKDLPSVPP 
LELSVPADYP AQSPLWIDRQ WQYDANPFLQ SVHRCMTSRL LQLPDKHSVT ALLNTWAQSV 
HQACLSAA

Genular Protein ID: 1014898977

Symbol: B7Z2H7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z2H7

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 6 RefSeq 1 RuleBase 1 SAM 1

Sequence Information:

  • Length: 722
  • Mass: 79610
  • Checksum: F3BA5CDCA7EF838F
  • Sequence:
    • MRKAGVAHSK SSKDMESHVF LKAKTRDEYL SLVARLIIHF RDIHNKKSQA SVSDPMNALQ 
SLTGGPAAGA AGIGMPPRGP GQSLGGMGSL GAMGQPMSLS GQPPPGTSGM APHSMAVVST 
ATPQTQLQLQ QVALQQQQQQ QQFQQQQQAA LQQQQQQQQQ QQFQAQQSAM QQQFQAVVQQ 
QQQLQQQQQQ QQHLIKLHHQ NQQQIQQQQQ QLQRIAQLQL QQQQQQQQQQ QQQQQQALQA 
QPPIQQPPMQ QPQPPPSQAL PQQLQQMHHT QHHQPPPQPQ QPPVAQNQPS QLPPQSQTQP 
LVSQAQALPG QMLYTQPPLK FVRAPMVVQQ PPVQPQVQQQ QTAVQTAQAA QMVAPGVQVS 
QSSLPMLSSP SPGQQVQTPQ SMPPPPQPSP QPGQPSSQPN SNVSSGPAPS PSSFLPSPSP 
QPSQSPVTAR TPQNFSVPSP GPLNTPVNPS SVMSPAGSSQ AEEQQYLDKL KQLSKYIEPL 
RRMINKIDKN EDRKKDLSKM KSLLDILTDP SKRCPLKTLQ KCEIALEKLK NDMAVPTPPP 
PPVPPTKQQY LCQPLLDAVL ANIRSPVFNH SLYRTFVPAM TAIHGPPITA PVVCTRKRRL 
EDDERQSIPS VLQGEVARLD PKFLVNLDPS HCSNNGTVHL ICKLDDKDLP SVPPLELSVP 
ADYPAQSPLW IDRQWQYDAN PFLQSVHRCM TSRLLQLPDK HSVTALLNTW AQSVHQACLP 
AA

Genular Protein ID: 1044162254

Symbol: G3V1P5_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3V1P5

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 6 Proteomes 2 ProteomicsDB 2 RefSeq 2 RuleBase 1 SAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 722
  • Mass: 79600
  • Checksum: F3BA5E0CA7EF838F
  • Sequence:
    • MRKAGVAHSK SSKDMESHVF LKAKTRDEYL SLVARLIIHF RDIHNKKSQA SVSDPMNALQ 
SLTGGPAAGA AGIGMPPRGP GQSLGGMGSL GAMGQPMSLS GQPPPGTSGM APHSMAVVST 
ATPQTQLQLQ QVALQQQQQQ QQFQQQQQAA LQQQQQQQQQ QQFQAQQSAM QQQFQAVVQQ 
QQQLQQQQQQ QQHLIKLHHQ NQQQIQQQQQ QLQRIAQLQL QQQQQQQQQQ QQQQQQALQA 
QPPIQQPPMQ QPQPPPSQAL PQQLQQMHHT QHHQPPPQPQ QPPVAQNQPS QLPPQSQTQP 
LVSQAQALPG QMLYTQPPLK FVRAPMVVQQ PPVQPQVQQQ QTAVQTAQAA QMVAPGVQVS 
QSSLPMLSSP SPGQQVQTPQ SMPPPPQPSP QPGQPSSQPN SNVSSGPAPS PSSFLPSPSP 
QPSQSPVTAR TPQNFSVPSP GPLNTPVNPS SVMSPAGSSQ AEEQQYLDKL KQLSKYIEPL 
RRMINKIDKN EDRKKDLSKM KSLLDILTDP SKRCPLKTLQ KCEIALEKLK NDMAVPTPPP 
PPVPPTKQQY LCQPLLDAVL ANIRSPVFNH SLYRTFVPAM TAIHGPPITA PVVCTRKRRL 
EDDERQSIPS VLQGEVARLD PKFLVNLDPS HCSNNGTVHL ICKLDDKDLP SVPPLELSVP 
ADYPAQSPLW IDRQWQYDAN PFLQSVHRCM TSRLLQLPDK HSVTALLNTW AQSVHQACLS 
AA

Genular Protein ID: 457653399

Symbol: Q6PKB8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PKB8

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 6 RefSeq 3 RuleBase 1 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 767
  • Mass: 84358
  • Checksum: 0C78349546139265
  • Sequence:
    • ARGLRRRRWR PSGIRAAGAG EQAWTFPGKR PTGGAPPSGR SCEDAMRKAG VAHSKSSKDM 
ESHVFLKAKT RDEYLSLVAR LIIHFRDIHN KKSQASVSDP MNALQSLTGG PAAGAAGIGM 
PPRGPGQSLG GMGSLGATGQ PMSLSGQPPP GTSGMAPHSM AVVSTATPQT QLQLQQVALQ 
QQQQQQQFQQ QQQAALQQQQ QQQQQQQFQA QQSAMQQQFQ AVVQQQQQLQ QQQQQQQHLI 
KLHHQNQQQI QQQQQQLQRI AQLQLQQQQQ QQQQQQQQQQ QALQAQPPIQ QPPMQQPQPP 
PSQALPQQLQ QMHHTQHHQP PPQPQQPPVA QNQPSQLPPQ SQTQPLVSQA QALPGQMLYT 
QPPLKFVRAP MVVQQPPVQP QVQQQQTAVQ TAQAAQMVAP GVQVSQSSLP MLSSPSPGQQ 
VQTPQSMPPP PQPSPQPGQP SSQPNSNVSS GPAPSPSSFL PSPSPQPSQS PVTARTPQNF 
SVPSPGPLNT PVNPSSVMSP AGSSQAEEQQ YLDKLKQLSK YIEPLRRMIN KIDKNEDRKK 
DLSKMKSLLD ILTDPSKRCP LKTLQKCEIA LEKLKNDMAV PTPPPPPVPP TKQQYLCQPL 
LDAVLANIRS PVFNHSLYRT FVPAMTAIHG PPITAPVVCT RKRRLEDDER QSIPSVLQGE 
VARLDPKFLV NLDPSHCSNN GTVHLICKLD DKDLPSVPPL ELSVPADYPA QSPLWIDRQW 
QYDANPFLQS VHRCMTSRLL QLPDKHSVTA LLNTWAQSVH QACLSAA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.