Details for: PGK1

Gene ID: 5230

Symbol: PGK1

Ensembl ID: ENSG00000102144

Description: phosphoglycerate kinase 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 4.57
    Marker Score: 3225
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 4.22
    Marker Score: 2561
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 4.12
    Marker Score: 4972
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 4.06
    Marker Score: 16884
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 3.77
    Marker Score: 3558.5
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 3.72
    Marker Score: 3160
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 3.66
    Marker Score: 3268
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.57
    Marker Score: 35361
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 3.44
    Marker Score: 2302
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 3.35
    Marker Score: 9252
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.34
    Marker Score: 38791
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 3.2
    Marker Score: 937
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 3.16
    Marker Score: 6422
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.09
    Marker Score: 172925
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 3.07
    Marker Score: 4350
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.99
    Marker Score: 3614
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 2.94
    Marker Score: 2222
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 2.93
    Marker Score: 5239
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.93
    Marker Score: 7394
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 2.91
    Marker Score: 3040
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.87
    Marker Score: 99322.5
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.86
    Marker Score: 7675
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.82
    Marker Score: 12100
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.77
    Marker Score: 146589
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 2.77
    Marker Score: 5399
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 2.76
    Marker Score: 36723.5
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.73
    Marker Score: 8617
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.7
    Marker Score: 3093
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 2.7
    Marker Score: 3746
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.69
    Marker Score: 5907.5
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 2.68
    Marker Score: 2594
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.67
    Marker Score: 17088
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.66
    Marker Score: 1520
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 2.66
    Marker Score: 1375
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 2.66
    Marker Score: 1484
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.64
    Marker Score: 3557
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 2.63
    Marker Score: 20570
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 2.63
    Marker Score: 3159
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.63
    Marker Score: 9329.5
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 2.62
    Marker Score: 1382
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 2.62
    Marker Score: 22618
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.61
    Marker Score: 10691
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 2.59
    Marker Score: 1577
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.59
    Marker Score: 1719
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 2.56
    Marker Score: 1849
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.54
    Marker Score: 4219
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.52
    Marker Score: 1028
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.52
    Marker Score: 1314
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 2.48
    Marker Score: 1408
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 2.47
    Marker Score: 6015
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.46
    Marker Score: 4812
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.45
    Marker Score: 2063
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 2.45
    Marker Score: 2541
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 2.45
    Marker Score: 6863
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.44
    Marker Score: 24757
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 2.44
    Marker Score: 1055
  • Cell Name: ventricular cardiac muscle cell (CL2000046)
    Fold Change: 2.43
    Marker Score: 1010
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.42
    Marker Score: 2566
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.42
    Marker Score: 2418
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.42
    Marker Score: 6574
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.41
    Marker Score: 61736
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 2.41
    Marker Score: 5814
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.41
    Marker Score: 1754
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 2.4
    Marker Score: 2137
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 2.39
    Marker Score: 32159
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 2.39
    Marker Score: 5946
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.38
    Marker Score: 4223
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.38
    Marker Score: 10260
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.37
    Marker Score: 2402
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.37
    Marker Score: 565
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 2.36
    Marker Score: 3340
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.34
    Marker Score: 23575
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 2.34
    Marker Score: 1249
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.34
    Marker Score: 1368
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.33
    Marker Score: 5701.5
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.33
    Marker Score: 4057
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.33
    Marker Score: 1762
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.32
    Marker Score: 4842
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.32
    Marker Score: 17251
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 2.32
    Marker Score: 1677
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 2.31
    Marker Score: 2331
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.3
    Marker Score: 1804.5
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.3
    Marker Score: 2017
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.28
    Marker Score: 1331
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.28
    Marker Score: 2138
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 2.28
    Marker Score: 840
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 2.27
    Marker Score: 1857.5
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 2.27
    Marker Score: 945
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 2.25
    Marker Score: 6574
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.25
    Marker Score: 2115
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 2.24
    Marker Score: 2648
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.24
    Marker Score: 1120
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 2.23
    Marker Score: 1525.5
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.22
    Marker Score: 2420
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: 2.22
    Marker Score: 1226
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 2.21
    Marker Score: 487
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 2.21
    Marker Score: 3509
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 2.2
    Marker Score: 707
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.2
    Marker Score: 6531
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 2.19
    Marker Score: 1472

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Other Information

**Key Characteristics** 1. **Mitochondrial localization**: PGK1 is predominantly found in the mitochondrial matrix, where it plays a crucial role in energy production. 2. **ATP-generating activity**: PGK1 is responsible for producing ATP through the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate. 3. **Regulation of energy metabolism**: PGK1 is involved in the regulation of energy metabolism, particularly under hypoxic conditions, where it helps maintain ATP production. 4. **Immune cell expression**: PGK1 is highly expressed in immune cells, such as monocytes, dendritic cells, and T cells, highlighting its role in immune function. **Pathways and Functions** PGK1 is involved in various metabolic pathways, including: 1. **Glycolysis**: PGK1 is a key enzyme in the glycolytic pathway, where it generates ATP by converting 1,3-bisphosphoglycerate to 3-phosphoglycerate. 2. **Gluconeogenesis**: PGK1 is also involved in gluconeogenesis, where it helps generate glucose from non-carbohydrate sources. 3. **Canonical glycolysis**: PGK1 is a critical component of the canonical glycolytic pathway, where it plays a central role in energy production. 4. **Cellular response to hypoxia**: PGK1 is induced under hypoxic conditions, where it helps maintain ATP production and support cellular survival. 5. **Infection with mycobacterium tuberculosis**: PGK1 is involved in the regulation of energy metabolism during M. tuberculosis infection, highlighting its importance in immune response. **Clinical Significance** The dysregulation of PGK1 has been implicated in various diseases, including: 1. **Cancer**: Altered PGK1 expression has been observed in various types of cancer, where it contributes to tumor progression and metastasis. 2. **Neurodegenerative diseases**: PGK1 dysfunction has been linked to neurodegenerative diseases, such as Alzheimer's and Parkinson's, where it contributes to energy metabolism and neuronal survival. 3. **Immune disorders**: PGK1 is involved in the regulation of immune function, and its dysregulation has been implicated in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, PGK1 is a multifaceted enzyme that plays a critical role in metabolic regulation and immune function. Its dysregulation has been implicated in various diseases, highlighting the importance of PGK1 in maintaining energy homeostasis and immune function. Further research is needed to fully elucidate the role of PGK1 in human disease and to develop therapeutic strategies targeting this enzyme.

Genular Protein ID: 2630504915

Symbol: PGK1_HUMAN

Name: Phosphoglycerate kinase 1

UniProtKB Accession Codes:

P00558 A8K4W6 B7Z7A9 Q5J7W1 Q6IBT6 Q8NI87

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 2 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DOSAC-COBS-2DPAGE 1 DisGeNET 1 DrugBank 6 EC 1 EMBL 26 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonDB 1 MoonProt 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 31 PDBsum 25 PIR 1 PIRSF 1 PRIDE 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 3 RefSeq 1 Rhea 1 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCD-2DPAGE 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 6188151

Title: Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.

PubMed ID: 6188151

DOI: 10.1073/pnas.80.2.472

PubMed ID: 2995995

Title: Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain.

PubMed ID: 2995995

DOI: 10.1073/pnas.82.20.6965

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6099325

Title: Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase].

PubMed ID: 6099325

DOI: 10.1016/0378-1119(84)90016-7

PubMed ID: 2814502

Title: Genomic sequencing and methylation analysis by ligation mediated PCR.

PubMed ID: 2814502

DOI: 10.1126/science.2814502

PubMed ID: 7391027

Title: Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence.

PubMed ID: 7391027

DOI: 10.1016/s0021-9258(18)43754-4

PubMed ID: 2324090

Title: Functional identity of a primer recognition protein as phosphoglycerate kinase.

PubMed ID: 2324090

DOI: 10.1016/s0021-9258(19)39179-3

PubMed ID: 9075577

Title: Hematologically important mutations: molecular abnormalities of phosphoglycerate kinase.

PubMed ID: 9075577

DOI: 10.1006/bcmd.1996.0108

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21908771

Title: The first identification of lysine malonylation substrates and its regulatory enzyme.

PubMed ID: 21908771

DOI: 10.1074/mcp.m111.012658

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 26677959

Title: Characteristics of testis-specific phosphoglycerate kinase 2 and its association with human sperm quality.

PubMed ID: 26677959

DOI: 10.1093/humrep/dev301

PubMed ID: 29192674

Title: Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.

PubMed ID: 29192674

DOI: 10.1038/cr.2017.149

PubMed ID: 30323285

Title: A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling.

PubMed ID: 30323285

DOI: 10.1038/s41586-018-0622-0

PubMed ID: 29775581

Title: p300-mediated lysine 2-hydroxyisobutyrylation regulates glycolysis.

PubMed ID: 29775581

DOI: 10.1016/j.molcel.2018.04.011

PubMed ID: 18463139

Title: Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase.

PubMed ID: 18463139

DOI: 10.1093/nar/gkn212

PubMed ID: 8673469

Title: Molecular abnormality of a phosphoglycerate kinase variant (PGK-Alabama).

PubMed ID: 8673469

DOI: 10.1006/bcmd.1995.0020

PubMed ID: 8043870

Title: Identification of new mutations in two phosphoglycerate kinase (PGK) variants expressing different clinical syndromes: PGK Creteil and PGK Amiens.

PubMed ID: 8043870

PubMed ID: 8615693

Title: Retarded and aberrant splicings caused by single exon mutation in a phosphoglycerate kinase variant.

PubMed ID: 8615693

DOI: 10.1006/abbi.1996.0089

PubMed ID: 9744480

Title: A phosphoglycerate kinase mutant (PGK Herlev; D285V) in a Danish patient with isolated chronic hemolytic anemia: mechanism of mutation and structure-function relationships.

PubMed ID: 9744480

DOI: 10.1002/(sici)1098-1004(1998)12:4<280::aid-humu10>3.0.co;2-v

PubMed ID: 2001457

Title: Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu-->Pro substitution caused by T/A-->C/G transition in exon 3.

PubMed ID: 2001457

PubMed ID: 1586722

Title: Molecular abnormalities of a phosphoglycerate kinase variant generated by spontaneous mutation.

PubMed ID: 1586722

PubMed ID: 7391028

Title: A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK Munchen) associated with enzyme deficiency.

PubMed ID: 7391028

DOI: 10.1016/s0021-9258(18)43755-6

PubMed ID: 7440217

Title: Structure and function of normal and variant human phosphoglycerate kinase.

PubMed ID: 7440217

DOI: 10.3109/03630268008997730

PubMed ID: 1547346

Title: A single amino acid substitution (157 Gly-->Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria.

PubMed ID: 1547346

PubMed ID: 6941312

Title: Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia.

PubMed ID: 6941312

DOI: 10.1073/pnas.78.4.2587

PubMed ID: 6933565

Title: Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia.

PubMed ID: 6933565

DOI: 10.1073/pnas.77.9.5461

Sequence Information:

  • Length: 417
  • Mass: 44615
  • Checksum: B5DFC7B5FA01767C
  • Sequence:
    • MSLSNKLTLD KLDVKGKRVV MRVDFNVPMK NNQITNNQRI KAAVPSIKFC LDNGAKSVVL 
MSHLGRPDGV PMPDKYSLEP VAVELKSLLG KDVLFLKDCV GPEVEKACAN PAAGSVILLE 
NLRFHVEEEG KGKDASGNKV KAEPAKIEAF RASLSKLGDV YVNDAFGTAH RAHSSMVGVN 
LPQKAGGFLM KKELNYFAKA LESPERPFLA ILGGAKVADK IQLINNMLDK VNEMIIGGGM 
AFTFLKVLNN MEIGTSLFDE EGAKIVKDLM SKAEKNGVKI TLPVDFVTAD KFDENAKTGQ 
ATVASGIPAG WMGLDCGPES SKKYAEAVTR AKQIVWNGPV GVFEWEAFAR GTKALMDEVV 
KATSRGCITI IGGGDTATCC AKWNTEDKVS HVSTGGGASL ELLEGKVLPG VDALSNI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.