Details for: RALGDS
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 236.6514
Cell Significance Index: -36.8100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 143.7451
Cell Significance Index: -36.4600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 73.6233
Cell Significance Index: -29.9100 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 73.5773
Cell Significance Index: -30.3100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 31.4744
Cell Significance Index: -30.0500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 30.5850
Cell Significance Index: -37.7100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.2291
Cell Significance Index: -32.7600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.9753
Cell Significance Index: -33.7100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.6407
Cell Significance Index: -38.0400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.2662
Cell Significance Index: -20.2800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.4136
Cell Significance Index: 694.4700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.7196
Cell Significance Index: 89.3300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.4634
Cell Significance Index: 293.5600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.1389
Cell Significance Index: 20.1300 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.0635
Cell Significance Index: 23.0400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.0352
Cell Significance Index: 934.6700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8155
Cell Significance Index: 23.5000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.7616
Cell Significance Index: 39.6700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.6992
Cell Significance Index: 19.5400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.6823
Cell Significance Index: 244.7300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6534
Cell Significance Index: 71.0700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6298
Cell Significance Index: 38.7100 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.5905
Cell Significance Index: 76.2900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.5121
Cell Significance Index: 38.1700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.5051
Cell Significance Index: 23.5500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4941
Cell Significance Index: 80.3600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.4879
Cell Significance Index: 21.5800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4684
Cell Significance Index: 12.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4675
Cell Significance Index: 21.9700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.3989
Cell Significance Index: 15.1100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3964
Cell Significance Index: 48.7500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3882
Cell Significance Index: 211.9900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3680
Cell Significance Index: 16.6800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3461
Cell Significance Index: 153.0400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3334
Cell Significance Index: 60.1000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2993
Cell Significance Index: 20.7000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2778
Cell Significance Index: 52.8600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1532
Cell Significance Index: 15.1500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1353
Cell Significance Index: 3.2500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1162
Cell Significance Index: 14.9000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0833
Cell Significance Index: 16.5300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0293
Cell Significance Index: 2.2500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0291
Cell Significance Index: 4.0000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0198
Cell Significance Index: 1.1100 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.0155
Cell Significance Index: 0.2200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0068
Cell Significance Index: 9.2300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0026
Cell Significance Index: -4.9600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0026
Cell Significance Index: -4.7300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0032
Cell Significance Index: -0.0700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0043
Cell Significance Index: -6.6700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0134
Cell Significance Index: -0.2300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0229
Cell Significance Index: -0.5300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0355
Cell Significance Index: -26.8900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0368
Cell Significance Index: -23.3500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0387
Cell Significance Index: -28.4100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0426
Cell Significance Index: -31.5600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0569
Cell Significance Index: -32.0900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0641
Cell Significance Index: -40.0100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0668
Cell Significance Index: -30.3400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0696
Cell Significance Index: -4.9200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0802
Cell Significance Index: -8.1900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0850
Cell Significance Index: -1.1600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0953
Cell Significance Index: -6.4100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0970
Cell Significance Index: -3.4100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1026
Cell Significance Index: -17.5200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1102
Cell Significance Index: -7.1100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1311
Cell Significance Index: -15.2800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1442
Cell Significance Index: -3.0700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1660
Cell Significance Index: -24.1300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1827
Cell Significance Index: -38.4800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2075
Cell Significance Index: -24.4700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2286
Cell Significance Index: -26.1900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.2748
Cell Significance Index: -5.7000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3516
Cell Significance Index: -10.0800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3616
Cell Significance Index: -37.6500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.3808
Cell Significance Index: -9.5200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3849
Cell Significance Index: -10.1200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4117
Cell Significance Index: -32.6100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4240
Cell Significance Index: -22.2600 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.4410
Cell Significance Index: -5.4700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4692
Cell Significance Index: -29.5700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4813
Cell Significance Index: -29.5100 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.4818
Cell Significance Index: -8.3300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4977
Cell Significance Index: -15.9400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4980
Cell Significance Index: -14.2100 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: -0.5092
Cell Significance Index: -5.4600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5346
Cell Significance Index: -15.7000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.6030
Cell Significance Index: -6.8500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.6072
Cell Significance Index: -22.2900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.6194
Cell Significance Index: -8.8700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.6195
Cell Significance Index: -16.5700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.6311
Cell Significance Index: -16.9100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6346
Cell Significance Index: -20.2100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6509
Cell Significance Index: -21.3100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6836
Cell Significance Index: -11.4400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.6921
Cell Significance Index: -18.4800 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.7003
Cell Significance Index: -7.6300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7085
Cell Significance Index: -24.6200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7556
Cell Significance Index: -26.4700 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.7819
Cell Significance Index: -15.2600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3241726092
Symbol: GNDS_HUMAN
Name: Ral guanine nucleotide dissociation stimulator
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9365783
Title: Cloning and evaluation of RALGDS as a candidate for the tuberous sclerosis gene TSC1.
PubMed ID: 9365783
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10718198
Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10718198
PubMed ID: 7972015
Title: Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator.
PubMed ID: 7972015
PubMed ID: 27438768
Title: Ubiquitination of Innate Immune Regulator TRAF3 Orchestrates Expulsion of Intracellular Bacteria by Exocyst Complex.
PubMed ID: 27438768
PubMed ID: 9302994
Title: Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling.
PubMed ID: 9302994
DOI: 10.1038/nsb0997-694
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 914
- Mass: 100607
- Checksum: EA5A5CF25AF3D523
- Sequence:
MVQRMWAEAA GPAGGAEPLF PGSRRSRSVW DAVRLEVGVP DSCPVVLHSF TQLDPDLPRP ESSTQEIGEE LINGVIYSIS LRKVQLHHGG NKGQRWLGYE NESALNLYET CKVRTVKAGT LEKLVEHLVP AFQGSDLSYV TIFLCTYRAF TTTQQVLDLL FKRYGRCDAL TASSRYGCIL PYSDEDGGPQ DQLKNAISSI LGTWLDQYSE DFCQPPDFPC LKQLVAYVQL NMPGSDLERR AHLLLAQLEH SEPIEAEPEA LSPVPALKPT PELELALTPA RAPSPVPAPA PEPEPAPTPA PGSELEVAPA PAPELQQAPE PAVGLESAPA PALELEPAPE QDPAPSQTLE LEPAPAPVPS LQPSWPSPVV AENGLSEEKP HLLVFPPDLV AEQFTLMDAE LFKKVVPYHC LGSIWSQRDK KGKEHLAPTI RATVTQFNSV ANCVITTCLG NRSTKAPDRA RVVEHWIEVA RECRILKNFS SLYAILSALQ SNSIHRLKKT WEDVSRDSFR IFQKLSEIFS DENNYSLSRE LLIKEGTSKF ATLEMNPKRA QKRPKETGII QGTVPYLGTF LTDLVMLDTA MKDYLYGRLI NFEKRRKEFE VIAQIKLLQS ACNNYSIAPD EQFGAWFRAV ERLSETESYN LSCELEPPSE SASNTLRTKK NTAIVKRWSD RQAPSTELST SGSSHSKSCD QLRCGPYLSS GDIADALSVH SAGSSSSDVE EINISFVPES PDGQEKKFWE SASQSSPETS GISSASSSTS SSSASTTPVA ATRTHKRSVS GLCNSSSALP LYNQQVGDCC IIRVSLDVDN GNMYKSILVT SQDKAPAVIR KAMDKHNLEE EEPEDYELLQ ILSDDRKLKI PENANVFYAM NSTANYDFVL KKRTFTKGVK VKHGASSTLP RMKQKGLKIA KGIF
Genular Protein ID: 4089828044
Symbol: Q8N4Y1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 411
- Mass: 45526
- Checksum: 114CF1F26F923B79
- Sequence:
VSRDSFRIFQ KLSEIFSDEN NYSLSRELLI KEGTSKFATL EMNPKRAQKR PKETGIIQGT VPYLGTFLTD LVMLDTAMKD YLYGRLINFE KRRKEFEVIA QIKLLQSACN NYSIAPDEQF GAWFRAVERL SETESYNLSC ELEPPSESAS NTLRTKKNTA IVKRWSDRQA PSTELSTSGS SHSKSCDQLR CGPYLSSGDI ADALSVHSAG SSSSDVEEIN ISFVPESPDG QEKKFWESAS QSSPETSGIS SASSSTSSSS ASTTPVAATR THKRSVSGLC NSSSALPLYN QQVGDCCIIR VSLDVDNGNM YKSILVTSQD KAPAVIRKAM DKHNLEEEEP EDYELLQILS DDRKLKIPEN ANVFYAMNST ANYDFVLKKR TFTKGVKVKH GASSTLPRMK QKGLKIAKGI F
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.