Details for: BRD2

Gene ID: 6046

Symbol: BRD2

Ensembl ID: ENSG00000204256

Description: bromodomain containing 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 445.6903
    Cell Significance Index: -69.3300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 263.8547
    Cell Significance Index: -66.9300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 171.4431
    Cell Significance Index: -69.6500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 170.2312
    Cell Significance Index: -80.3700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 152.8038
    Cell Significance Index: -78.6000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 119.6682
    Cell Significance Index: -80.3000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 74.2189
    Cell Significance Index: -70.8600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 60.4482
    Cell Significance Index: -74.5300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 26.6923
    Cell Significance Index: -71.5100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 22.5691
    Cell Significance Index: -69.3200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 19.2040
    Cell Significance Index: -75.7800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.1944
    Cell Significance Index: -24.5000
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 6.4382
    Cell Significance Index: 90.3100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 4.4697
    Cell Significance Index: 572.9900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 4.4030
    Cell Significance Index: 161.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.6669
    Cell Significance Index: 99.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.7849
    Cell Significance Index: 126.2300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.3662
    Cell Significance Index: 67.8300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.2066
    Cell Significance Index: 114.9400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.1415
    Cell Significance Index: 100.6500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 2.1387
    Cell Significance Index: 262.9700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.0323
    Cell Significance Index: 18.7200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.9615
    Cell Significance Index: 353.5900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.5648
    Cell Significance Index: 45.0900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.4120
    Cell Significance Index: 8.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.3672
    Cell Significance Index: 746.6800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.2040
    Cell Significance Index: 41.8400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.2032
    Cell Significance Index: 165.2300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.0948
    Cell Significance Index: 129.1100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0932
    Cell Significance Index: 56.7900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0709
    Cell Significance Index: 69.0900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.0362
    Cell Significance Index: 458.1100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.0324
    Cell Significance Index: 21.6100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.9933
    Cell Significance Index: 46.3100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.8095
    Cell Significance Index: 104.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.7220
    Cell Significance Index: 53.8100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6748
    Cell Significance Index: 133.9200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5636
    Cell Significance Index: 15.7500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4845
    Cell Significance Index: 97.2000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.3787
    Cell Significance Index: 7.0000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.3636
    Cell Significance Index: 9.5600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3366
    Cell Significance Index: 120.7200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2991
    Cell Significance Index: 51.0700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2804
    Cell Significance Index: 45.6100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2295
    Cell Significance Index: 43.6800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2108
    Cell Significance Index: 24.0600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2070
    Cell Significance Index: 14.6400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.2016
    Cell Significance Index: 5.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1920
    Cell Significance Index: 10.0800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1766
    Cell Significance Index: 8.9300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1164
    Cell Significance Index: 105.0800
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.0629
    Cell Significance Index: 0.8100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0498
    Cell Significance Index: 4.9300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0084
    Cell Significance Index: 15.7400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0196
    Cell Significance Index: -14.8300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0233
    Cell Significance Index: -43.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0319
    Cell Significance Index: -49.0700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0341
    Cell Significance Index: -25.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0343
    Cell Significance Index: -3.5000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0402
    Cell Significance Index: -0.7100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0429
    Cell Significance Index: -58.2800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0457
    Cell Significance Index: -29.0300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0678
    Cell Significance Index: -1.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0752
    Cell Significance Index: -55.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0814
    Cell Significance Index: -36.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1136
    Cell Significance Index: -64.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1211
    Cell Significance Index: -75.6200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1558
    Cell Significance Index: -3.6000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1648
    Cell Significance Index: -12.6500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1989
    Cell Significance Index: -11.1600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2214
    Cell Significance Index: -3.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2758
    Cell Significance Index: -79.3500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2798
    Cell Significance Index: -40.6700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2826
    Cell Significance Index: -30.7400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2890
    Cell Significance Index: -33.1100
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.3153
    Cell Significance Index: -2.4300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3349
    Cell Significance Index: -21.1100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3495
    Cell Significance Index: -3.9700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3604
    Cell Significance Index: -75.9200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5305
    Cell Significance Index: -7.8300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5405
    Cell Significance Index: -62.9900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.6145
    Cell Significance Index: -6.6800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6973
    Cell Significance Index: -14.8500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6977
    Cell Significance Index: -72.6500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8438
    Cell Significance Index: -66.8300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.8552
    Cell Significance Index: -35.0400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.8784
    Cell Significance Index: -11.9900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.9707
    Cell Significance Index: -21.0300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -1.0161
    Cell Significance Index: -15.2300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.1418
    Cell Significance Index: -33.6300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.1428
    Cell Significance Index: -68.6100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1470
    Cell Significance Index: -70.3200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.1935
    Cell Significance Index: -12.3600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.3052
    Cell Significance Index: -57.7300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.3585
    Cell Significance Index: -34.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4077
    Cell Significance Index: -45.0900
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: -1.4192
    Cell Significance Index: -13.7300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -1.5968
    Cell Significance Index: -22.7300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.6143
    Cell Significance Index: -61.1300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.7008
    Cell Significance Index: -42.5200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Bromodomain structure:** BRD2 contains a bromodomain, a conserved domain that recognizes acetylated histones, allowing it to bind to chromatin and regulate gene expression. 2. **Acetylation-dependent protein binding:** BRD2's bromodomain interacts with acetylated histones, facilitating the recruitment of transcriptional machinery to specific gene loci. 3. **Chromatin binding and looping:** BRD2 interacts with chromatin-associated proteins to facilitate chromatin looping and the formation of nuclear speck-like structures, which are essential for transcriptional regulation. 4. **Protein phosphorylation and serine/threonine kinase activity:** BRD2 can be phosphorylated and exhibits serine/threonine kinase activity, regulating its activity and interactions with other proteins. **Pathways and Functions:** 1. **Gene expression (transcription):** BRD2 regulates gene expression by recruiting transcriptional machinery to specific gene loci, influencing the transcription of genes involved in immune response and cellular differentiation. 2. **Chromatin remodeling:** BRD2 interacts with chromatin-associated proteins to facilitate chromatin looping and the formation of nuclear speck-like structures, which are essential for transcriptional regulation. 3. **Protein localization to chromatin:** BRD2 regulates the localization of proteins to chromatin, influencing their activity and interactions with other proteins. 4. **Regulation of transcription by RNA polymerase II:** BRD2 interacts with RNA polymerase II to regulate transcription, influencing the expression of genes involved in immune response and cellular differentiation. **Clinical Significance:** 1. **Cancer:** BRD2 has been implicated in various cancers, including leukemia, lymphoma, and breast cancer, where its dysregulation can contribute to tumorigenesis and disease progression. 2. **Autoimmune disorders:** BRD2 has been implicated in autoimmune disorders, including rheumatoid arthritis and lupus, where its dysregulation can contribute to disease pathogenesis. 3. **Immune response:** BRD2 plays a crucial role in regulating the immune response, particularly in the context of T-cell differentiation and function. 4. **Stem cell regulation:** BRD2 regulates the expression of genes involved in stem cell maintenance and differentiation, influencing the development of various cell types. In conclusion, the BRD2 gene is a critical regulator of transcriptional regulation, immune response, and cellular differentiation. Its dysregulation has been implicated in various diseases, including cancer and autoimmune disorders. Further research is necessary to fully understand the mechanisms of BRD2 and its role in human disease.

Genular Protein ID: 1101594428

Symbol: BRD2_HUMAN

Name: O27.1.1

UniProtKB Accession Codes:

P25440 A2AAU0 B0S7P0 B1AZT1 O00699 O00700 Q15310 Q5STC9 Q63HQ9 Q658Y7 Q6P3U2 Q969U4

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CPTAC 1 CTD 1 ChEBI 14 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 18 Ensembl 17 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 100 PDBsum 100 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 SASBDB 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1352711

Title: A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC.

PubMed ID: 1352711

DOI: 10.3109/10425179209020804

PubMed ID: 8781126

Title: Phylogeny and structure of the RING3 gene.

PubMed ID: 8781126

DOI: 10.1007/bf02602785

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16227282

Title: Brd2/RING3 interacts with a chromatin-binding domain in the Kaposi's Sarcoma-associated herpesvirus latency-associated nuclear antigen 1 (LANA-1) that is required for multiple functions of LANA-1.

PubMed ID: 16227282

DOI: 10.1128/jvi.79.21.13618-13629.2005

PubMed ID: 18406326

Title: The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription.

PubMed ID: 18406326

DOI: 10.1016/j.molcel.2008.01.018

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 35410381

Title: BRD2 compartmentalizes the accessible genome.

PubMed ID: 35410381

DOI: 10.1038/s41588-022-01044-9

PubMed ID: 17848202

Title: Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails.

PubMed ID: 17848202

DOI: 10.1186/1472-6807-7-57

PubMed ID: 17148447

Title: Crystal structure of the human BRD2 bromodomain: insights into dimerization and recognition of acetylated histone h4.

PubMed ID: 17148447

DOI: 10.1074/jbc.m605971200

PubMed ID: 20709061

Title: Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2.

PubMed ID: 20709061

DOI: 10.1016/j.febslet.2010.08.013

PubMed ID: 20048151

Title: Structural basis for acetylated histone H4 recognition by the human BRD2 bromodomain.

PubMed ID: 20048151

DOI: 10.1074/jbc.m109.062422

PubMed ID: 20871596

Title: Selective inhibition of BET bromodomains.

PubMed ID: 20871596

DOI: 10.1038/nature09504

PubMed ID: 28262505

Title: Distinct roles of Brd2 and Brd4 in potentiating the transcriptional program for th17 cell differentiation.

PubMed ID: 28262505

DOI: 10.1016/j.molcel.2016.12.022

PubMed ID: 31969702

Title: Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.

PubMed ID: 31969702

DOI: 10.1038/s41586-020-1930-8

PubMed ID: 32193360

Title: Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.

PubMed ID: 32193360

DOI: 10.1126/science.aaz8455

PubMed ID: 37731000

Title: Acetyl-methyllysine marks chromatin at active transcription start sites.

PubMed ID: 37731000

DOI: 10.1038/s41586-023-06565-9

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 801
  • Mass: 88061
  • Checksum: 9A075EEB13507D8E
  • Sequence:
    • MLQNVTPHNK LPGEGNAGLL GLGPEAAAPG KRIRKPSLLY EGFESPTMAS VPALQLTPAN 
PPPPEVSNPK KPGRVTNQLQ YLHKVVMKAL WKHQFAWPFR QPVDAVKLGL PDYHKIIKQP 
MDMGTIKRRL ENNYYWAASE CMQDFNTMFT NCYIYNKPTD DIVLMAQTLE KIFLQKVASM 
PQEEQELVVT IPKNSHKKGA KLAALQGSVT SAHQVPAVSS VSHTALYTPP PEIPTTVLNI 
PHPSVISSPL LKSLHSAGPP LLAVTAAPPA QPLAKKKGVK RKADTTTPTP TAILAPGSPA 
SPPGSLEPKA ARLPPMRRES GRPIKPPRKD LPDSQQQHQS SKKGKLSEQL KHCNGILKEL 
LSKKHAAYAW PFYKPVDASA LGLHDYHDII KHPMDLSTVK RKMENRDYRD AQEFAADVRL 
MFSNCYKYNP PDHDVVAMAR KLQDVFEFRY AKMPDEPLEP GPLPVSTAMP PGLAKSSSES 
SSEESSSESS SEEEEEEDEE DEEEEESESS DSEEERAHRL AELQEQLRAV HEQLAALSQG 
PISKPKRKRE KKEKKKKRKA EKHRGRAGAD EDDKGPRAPR PPQPKKSKKA SGSGGGSAAL 
GPSGFGPSGG SGTKLPKKAT KTAPPALPTG YDSEEEEESR PMSYDEKRQL SLDINKLPGE 
KLGRVVHIIQ AREPSLRDSN PEEIEIDFET LKPSTLRELE RYVLSCLRKK PRKPYTIKKP 
VGKTKEELAL EKKRELEKRL QDVSGQLNST KKPPKKANEK TESSSAQQVA VSRLSASSSS 
SDSSSSSSSS SSSDTSDSDS G

Genular Protein ID: 4023718434

Symbol: X5CF57_HUMAN

Name: N/A

UniProtKB Accession Codes:

X5CF57

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 GO 2 Gene3D 2 HOGENOM 1 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1

Sequence Information:

  • Length: 754
  • Mass: 83151
  • Checksum: 2DC450BD2727B979
  • Sequence:
    • MASVPALQLT PANPPPPEVS NPKKPGRVTN QLQYLHKVVM KALWKHQFAW PFRQPVDAVK 
LGLPDYHKII KQPMDMGTIK RRLENNYYWA ASECMQDFNT MFTNCYIYNK PTDDIVLMAQ 
TLEKIFLQKV ASMPQEEQEL VVTIPKNSHK KGAKLAALQG SVTSAHQVPA VSSVSHTALY 
TPPPEIPTTV LNIPHPSVIS SPLLKSLHSA GPPLLAVTAA PPAQPLAKKK GVKRKADTTT 
PTPTAILAPG SPASPPGSLE PKAARLPPMR RESGRPIKPP RKDLPDSQQQ HQSSKKGKLS 
EQLKHCNGIL KELLSKKHAA YAWPFYKPVD ASALGLHDYH DIIKHPMDLS TVKRKMENRD 
YRDAQEFAAD VRLMFSNCYK YNPPDHDVVA MARKLQDVFE FRYAKMPDEP LEPGPLPVST 
AMPPGLAKSS SESSSEESSS ESSSEEEEEE DEEDEEEEES ESSDSEEERA HRLAELQEQL 
RAVHEQLAAL SQGPISKPKR KREKKEKKKK RKAEKHRGRA GADEDDKGPR APRPPQPKKS 
KKASGSGGGS AALGPSGFGP SGGSGTKLPK KATKTAPPAL PTGYDSEEEE ESRPMSYDEK 
RQLSLDINKL PGEKLGRVVH IIQAREPSLR DSNPEEIEID FETLKPSTLR ELERYVLSCL 
RKKPRKPYTI KKPVGKTKEE LALEKKRELE KRLQDVSGQL NSTKKPPKKA NEKTESSSAQ 
QVAVSRLSAS SSSSDSSSSS SSSSSSDTSD SDSG

Genular Protein ID: 3322103527

Symbol: A0A1U9X7A8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1U9X7A8

Database IDs:

ARBA 7 AlphaFoldDB 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 7 GO 2 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PROSITE-ProRule 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 681
  • Mass: 74881
  • Checksum: 22CE98AEC0994F92
  • Sequence:
    • MDMGTIKRRL ENNYYWAASE CMQDFNTMFT NCYIYNKPTD DIVLMAQTLE KIFLQKVASM 
PQEEQELVVT IPKNSHKKGA KLAALQGSVT SAHQVPAVSS VSHTALYTPP PEIPTTVLNI 
PHPSVISSPL LKSLHSAGPP LLAVTAAPPA QPLAKKKGVK RKADTTTPTP TAILAPGSPA 
SPPGSLEPKA ARLPPMRRES GRPIKPPRKD LPDSQQQHQS SKKGKLSEQL KHCNGILKEL 
LSKKHAAYAW PFYKPVDASA LGLHDYHDII KHPMDLSTVK RKMENRDYRD AQEFAADVRL 
MFSNCYKYNP PDHDVVAMAR KLQDVFEFRY AKMPDEPLEP GPLPVSTAMP PGLAKSSSES 
SSEESSSESS SEEEEEEDEE DEEEEESESS DSEEERAHRL AELQEQLRAV HEQLAALSQG 
PISKPKRKRE KKEKKKKRKA EKHRGRAGAD EDDKGPRAPR PPQPKKSKKA SGSGGGSAAL 
GPSGFGPSGG SGTKLPKKAT KTAPPALPTG YDSEEEEESR PMSYDEKRQL SLDINKLPGE 
KLGRVVHIIQ AREPSLRDSN PEEIEIDFET LKPSTLRELE RYVLSCLRKK PRKPYTIKKP 
VGKTKEELAL EKKRELEKRL QDVSGQLNST KKPPKKANEK TESSSAQQVA VSRLSASSSS 
SDSSSSSSSS SSSDTSDSDS G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.