Details for: RNH1

Gene ID: 6050

Symbol: RNH1

Ensembl ID: ENSG00000023191

Description: ribonuclease/angiogenin inhibitor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 396.7335
    Cell Significance Index: -61.7100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 251.8891
    Cell Significance Index: -63.8900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 169.9002
    Cell Significance Index: -69.9900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 156.7973
    Cell Significance Index: -63.7000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 154.5573
    Cell Significance Index: -72.9700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 137.1735
    Cell Significance Index: -70.5600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 109.1916
    Cell Significance Index: -73.2700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 67.5575
    Cell Significance Index: -64.5000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 56.4822
    Cell Significance Index: -69.6400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.7542
    Cell Significance Index: -50.2400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 18.2157
    Cell Significance Index: -71.8800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 16.5199
    Cell Significance Index: -50.7400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.7786
    Cell Significance Index: -23.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.7264
    Cell Significance Index: 374.4100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.6231
    Cell Significance Index: 71.4000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.1596
    Cell Significance Index: 129.6500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.0498
    Cell Significance Index: 37.8900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.9571
    Cell Significance Index: 91.9800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.8256
    Cell Significance Index: 85.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.7151
    Cell Significance Index: 210.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.7102
    Cell Significance Index: 308.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.5744
    Cell Significance Index: 45.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.5114
    Cell Significance Index: 112.6400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.4960
    Cell Significance Index: 191.7800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.4352
    Cell Significance Index: 16.3100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.4114
    Cell Significance Index: 624.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.3835
    Cell Significance Index: 71.8700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.3828
    Cell Significance Index: 24.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2981
    Cell Significance Index: 708.9400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.2798
    Cell Significance Index: 90.5100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.2617
    Cell Significance Index: 163.0000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.0550
    Cell Significance Index: 68.0700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.0488
    Cell Significance Index: 54.6300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.0333
    Cell Significance Index: 9.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.8693
    Cell Significance Index: 45.6400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7182
    Cell Significance Index: 15.5600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.6781
    Cell Significance Index: 17.8300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.6315
    Cell Significance Index: 18.5500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.6250
    Cell Significance Index: 14.4400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.6175
    Cell Significance Index: 177.6900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5726
    Cell Significance Index: 15.2900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5161
    Cell Significance Index: 102.4300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4428
    Cell Significance Index: 20.0700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.4271
    Cell Significance Index: 8.9400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4131
    Cell Significance Index: 28.5700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3627
    Cell Significance Index: 72.7600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3138
    Cell Significance Index: 8.7700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3022
    Cell Significance Index: 57.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2507
    Cell Significance Index: 42.8200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2251
    Cell Significance Index: 26.5500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1528
    Cell Significance Index: 7.7200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1141
    Cell Significance Index: 7.1900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1129
    Cell Significance Index: 40.5100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0855
    Cell Significance Index: 64.6800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0681
    Cell Significance Index: 1.1400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0542
    Cell Significance Index: 5.3600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0239
    Cell Significance Index: 17.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0171
    Cell Significance Index: 32.1900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0020
    Cell Significance Index: 0.2000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0027
    Cell Significance Index: -4.8900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0095
    Cell Significance Index: -14.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0281
    Cell Significance Index: -20.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0351
    Cell Significance Index: -47.7000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0421
    Cell Significance Index: -26.7500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0483
    Cell Significance Index: -1.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0536
    Cell Significance Index: -33.4900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0655
    Cell Significance Index: -45.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0803
    Cell Significance Index: -45.3100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0951
    Cell Significance Index: -43.1600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1388
    Cell Significance Index: -2.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1592
    Cell Significance Index: -33.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2092
    Cell Significance Index: -24.3800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.2310
    Cell Significance Index: -37.5700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2958
    Cell Significance Index: -33.8900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2998
    Cell Significance Index: -43.5800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3954
    Cell Significance Index: -8.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4046
    Cell Significance Index: -31.0500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4288
    Cell Significance Index: -5.8500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4486
    Cell Significance Index: -18.3800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5636
    Cell Significance Index: -64.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5814
    Cell Significance Index: -46.0500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6451
    Cell Significance Index: -16.4800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6597
    Cell Significance Index: -68.7000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.7441
    Cell Significance Index: -9.5300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.7654
    Cell Significance Index: -20.5100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.8413
    Cell Significance Index: -47.2100
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.8512
    Cell Significance Index: -7.1500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.9202
    Cell Significance Index: -17.9600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.0411
    Cell Significance Index: -12.4100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.1401
    Cell Significance Index: -69.9000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -1.1682
    Cell Significance Index: -12.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.2159
    Cell Significance Index: -53.7800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.2820
    Cell Significance Index: -41.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.3599
    Cell Significance Index: -40.0600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.4404
    Cell Significance Index: -54.5400
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -1.4466
    Cell Significance Index: -8.7400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.5182
    Cell Significance Index: -37.9500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.5183
    Cell Significance Index: -26.0200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.5433
    Cell Significance Index: -39.6700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.5447
    Cell Significance Index: -41.3200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RNH1 is a ribonuclease inhibitor that exhibits a unique structure, comprising two distinct domains: a ribonuclease inhibitor domain and an angiogenin-binding domain. The ribonuclease inhibitor domain is responsible for binding to ribonucleases, thereby inhibiting their activity, while the angiogenin-binding domain interacts with angiogenin, a potent angiogenic factor. This dual functionality allows RNH1 to modulate both ribonuclease activity and angiogenesis. **Pathways and Functions:** RNH1 is involved in several key biological pathways, including: 1. **Angiogenin-pri complex regulation:** RNH1 interacts with angiogenin, a potent angiogenic factor, to regulate its activity. This interaction is crucial for controlling angiogenesis, a process essential for tissue growth and development. 2. **Cell migration:** RNH1 is expressed in myeloid leukocytes and plays a role in regulating cell migration, a process essential for immune responses and tissue repair. 3. **mRNA catabolic process:** RNH1 inhibits ribonucleases, which are involved in mRNA degradation. This inhibition regulates mRNA catabolism, thereby modulating protein synthesis and cellular homeostasis. 4. **Regulation of ARP2/3 complex-mediated actin nucleation:** RNH1 interacts with the ARP2/3 complex, a key regulator of actin nucleation, to modulate its activity. This interaction is essential for regulating cell migration and cytoskeletal dynamics. **Clinical Significance:** RNH1's involvement in angiogenesis, cell migration, and immune regulation makes it a potential biomarker for various diseases, including: 1. **Cancer:** Altered RNH1 expression has been implicated in cancer progression, suggesting its potential as a prognostic marker. 2. **Inflammatory diseases:** RNH1's role in regulating immune responses makes it a potential therapeutic target for inflammatory diseases, such as rheumatoid arthritis and atherosclerosis. 3. **Neurological disorders:** RNH1's involvement in angiogenesis and cell migration suggests its potential role in neurological disorders, such as multiple sclerosis and stroke. In conclusion, RNH1 is a multifunctional protein that plays a critical role in regulating angiogenesis, cell migration, and immune responses. Its dysregulation has been implicated in various diseases, highlighting the need for further research into its molecular mechanisms and therapeutic potential.

Genular Protein ID: 1593395811

Symbol: RINI_HUMAN

Name: Ribonuclease inhibitor

UniProtKB Accession Codes:

P13489 Q8IZK8 Q96FD7 Q9BQ80 Q9UDK6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 16 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRIDE 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 RefSeq 17 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3219362

Title: Primary structure of human placental ribonuclease inhibitor.

PubMed ID: 3219362

DOI: 10.1021/bi00423a007

PubMed ID: 3243277

Title: The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module.

PubMed ID: 3243277

DOI: 10.1002/j.1460-2075.1988.tb03310.x

PubMed ID: 14515218

Title: Expression of a human ribonuclease inhibitor variant in Escherichia coli and silkworm insect cell (Bombyx mori).

PubMed ID: 14515218

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8037455

Title: Purification and characterization of human brain ribonuclease inhibitor.

PubMed ID: 8037455

DOI: 10.1006/abbi.1994.1328

PubMed ID: 1633192

Title: Characterisation of a tryptic peptide from human placental ribonuclease inhibitor which inhibits ribonuclease activity.

PubMed ID: 1633192

DOI: 10.1016/0167-4838(92)90134-y

PubMed ID: 9050852

Title: Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A.

PubMed ID: 9050852

DOI: 10.1073/pnas.94.5.1761

PubMed ID: 10413501

Title: Superadditive and subadditive effects of 'hot spot' mutations within the interfaces of placental ribonuclease inhibitor with angiogenin and ribonuclease A.

PubMed ID: 10413501

DOI: 10.1021/bi990762a

PubMed ID: 12578357

Title: Mutational analysis of the complex of human RNase inhibitor and human eosinophil-derived neurotoxin (RNase 2).

PubMed ID: 12578357

DOI: 10.1021/bi026852o

PubMed ID: 17292889

Title: The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis.

PubMed ID: 17292889

DOI: 10.1016/j.febslet.2007.01.072

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 36935417

Title: Ribonuclease inhibitor 1 (RNH1) deficiency cause congenital cataracts and global developmental delay with infection-induced psychomotor regression and anemia.

PubMed ID: 36935417

DOI: 10.1038/s41431-023-01327-7

PubMed ID: 9311977

Title: Molecular recognition of human angiogenin by placental ribonuclease inhibitor -- an X-ray crystallographic study at 2.0-A resolution.

PubMed ID: 9311977

DOI: 10.1093/emboj/16.17.5162

PubMed ID: 15755456

Title: Molecular recognition of human eosinophil-derived neurotoxin (RNase 2) by placental ribonuclease inhibitor.

PubMed ID: 15755456

DOI: 10.1016/j.jmb.2005.01.035

PubMed ID: 17350650

Title: Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.

PubMed ID: 17350650

DOI: 10.1016/j.jmb.2007.02.005

PubMed ID: 37191094

Title: Biallelic variants in ribonuclease inhibitor (RNH1), an inflammasome modulator, are associated with a distinctive subtype of acute, necrotizing encephalopathy.

PubMed ID: 37191094

DOI: 10.1016/j.gim.2023.100897

Sequence Information:

  • Length: 461
  • Mass: 49973
  • Checksum: 5E88CDAC95BAE5B3
  • Sequence:
    • MSLDIQSLDI QCEELSDARW AELLPLLQQC QVVRLDDCGL TEARCKDISS ALRVNPALAE 
LNLRSNELGD VGVHCVLQGL QTPSCKIQKL SLQNCCLTGA GCGVLSSTLR TLPTLQELHL 
SDNLLGDAGL QLLCEGLLDP QCRLEKLQLE YCSLSAASCE PLASVLRAKP DFKELTVSNN 
DINEAGVRVL CQGLKDSPCQ LEALKLESCG VTSDNCRDLC GIVASKASLR ELALGSNKLG 
DVGMAELCPG LLHPSSRLRT LWIWECGITA KGCGDLCRVL RAKESLKELS LAGNELGDEG 
ARLLCETLLE PGCQLESLWV KSCSFTAACC SHFSSVLAQN RFLLELQISN NRLEDAGVRE 
LCQGLGQPGS VLRVLWLADC DVSDSSCSSL AATLLANHSL RELDLSNNCL GDAGILQLVE 
SVRQPGCLLE QLVLYDIYWS EEMEDRLQAL EKDKPSLRVI S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.