RPLP0 | ENSG00000089157 | NCBI 6175

Details for: RPLP0

Gene ID: 6175

Symbol: RPLP0

Ensembl ID: ENSG00000089157

Description: ribosomal protein lateral stalk subunit P0

Associated with

Axon guidance
(R-HSA-422475)
Cap-dependent translation initiation
(R-HSA-72737)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Cytokine signaling in immune system
(R-HSA-1280215)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Eukaryotic translation elongation
(R-HSA-156842)
Eukaryotic translation initiation
(R-HSA-72613)
Eukaryotic translation termination
(R-HSA-72764)
Formation of a pool of free 40s subunits
(R-HSA-72689)
Gene and protein expression by jak-stat signaling after interleukin-12 stimulation
(R-HSA-8950505)
Gtp hydrolysis and joining of the 60s ribosomal subunit
(R-HSA-72706)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Influenza infection
(R-HSA-168255)
Influenza viral rna transcription and replication
(R-HSA-168273)
Interleukin-12 family signaling
(R-HSA-447115)
Interleukin-12 signaling
(R-HSA-9020591)
L13a-mediated translational silencing of ceruloplasmin expression
(R-HSA-156827)
Major pathway of rrna processing in the nucleolus and cytosol
(R-HSA-6791226)
Metabolism
(R-HSA-1430728)
Metabolism of amino acids and derivatives
(R-HSA-71291)
Metabolism of proteins
(R-HSA-392499)
Metabolism of rna
(R-HSA-8953854)
Nervous system development
(R-HSA-9675108)
Nonsense-mediated decay (nmd)
(R-HSA-927802)
Nonsense mediated decay (nmd) enhanced by the exon junction complex (ejc)
(R-HSA-975957)
Nonsense mediated decay (nmd) independent of the exon junction complex (ejc)
(R-HSA-975956)
Peptide chain elongation
(R-HSA-156902)
Regulation of expression of slits and robos
(R-HSA-9010553)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Rrna processing
(R-HSA-72312)
Rrna processing in the nucleus and cytosol
(R-HSA-8868773)
Selenoamino acid metabolism
(R-HSA-2408522)
Selenocysteine synthesis
(R-HSA-2408557)
Signaling by interleukins
(R-HSA-449147)
Signaling by robo receptors
(R-HSA-376176)
Srp-dependent cotranslational protein targeting to membrane
(R-HSA-1799339)
Viral infection pathways
(R-HSA-9824446)
Viral mrna translation
(R-HSA-192823)
Cytoplasm
(GO:0005737)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Cytoplasmic translation
(GO:0002181)
Cytosol
(GO:0005829)
Cytosolic large ribosomal subunit
(GO:0022625)
Cytosolic ribosome
(GO:0022626)
Endoplasmic reticulum
(GO:0005783)
Extracellular exosome
(GO:0070062)
Focal adhesion
(GO:0005925)
Large ribosomal subunit rrna binding
(GO:0070180)
Membrane
(GO:0016020)
Nucleus
(GO:0005634)
Postsynapse
(GO:0098794)
Postsynaptic density
(GO:0014069)
Protein binding
(GO:0005515)
Ribonucleoprotein complex
(GO:1990904)
Rna binding
(GO:0003723)
Structural constituent of ribosome
(GO:0003735)
Translation
(GO:0006412)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: embryonic stem cell (CL0002322)
Fold Change: 626.1233
Cell Significance Index: -257.9300
Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 522.7032
Cell Significance Index: -246.7800
Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 509.9583
Cell Significance Index: -262.3200
Cell Name: ileal goblet cell (CL1000326)
Fold Change: 368.6317
Cell Significance Index: -247.3600
Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 34.5865
Cell Significance Index: -92.6500
Cell Name: pro-T cell (CL0000827)
Fold Change: 19.0588
Cell Significance Index: 486.8900
Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 16.8209
Cell Significance Index: 178.7200
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 15.9897
Cell Significance Index: 204.7800
Cell Name: abnormal cell (CL0001061)
Fold Change: 14.6049
Cell Significance Index: 1491.8900
Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 14.5001
Cell Significance Index: 387.8700
Cell Name: theca cell (CL0000503)
Fold Change: 13.3940
Cell Significance Index: 78.6900
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 11.4747
Cell Significance Index: 398.7400
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 10.5099
Cell Significance Index: 219.9900
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 10.1095
Cell Significance Index: 475.1400
Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 10.0926
Cell Significance Index: 109.7200
Cell Name: lactocyte (CL0002325)
Fold Change: 9.9066
Cell Significance Index: 1279.8600
Cell Name: granulosa cell (CL0000501)
Fold Change: 9.8236
Cell Significance Index: 258.3100
Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 9.4934
Cell Significance Index: 278.8100
Cell Name: peg cell (CL4033014)
Fold Change: 9.2675
Cell Significance Index: 214.1100
Cell Name: sebum secreting cell (CL0000317)
Fold Change: 8.6362
Cell Significance Index: 610.7900
Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 8.4451
Cell Significance Index: 95.9400
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 8.3857
Cell Significance Index: 1151.6000
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 8.2659
Cell Significance Index: 974.8000
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 8.1861
Cell Significance Index: 1006.5600
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 7.9935
Cell Significance Index: 1440.9800
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 7.7583
Cell Significance Index: 578.2200
Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 7.7016
Cell Significance Index: 66.1800
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 7.5982
Cell Significance Index: 3359.3600
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 7.3019
Cell Significance Index: 340.4500
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 7.2182
Cell Significance Index: 127.5600
Cell Name: cell in vitro (CL0001034)
Fold Change: 6.8898
Cell Significance Index: 3762.6700
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 6.3065
Cell Significance Index: 180.7800
Cell Name: early pro-B cell (CL0002046)
Fold Change: 6.0704
Cell Significance Index: 391.6300
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 5.4945
Cell Significance Index: 4961.1100
Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 5.1289
Cell Significance Index: 47.2300
Cell Name: kidney cell (CL1000497)
Fold Change: 4.3248
Cell Significance Index: 34.5300
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 4.2625
Cell Significance Index: 727.8500
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 4.0309
Cell Significance Index: 107.6300
Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 3.9420
Cell Significance Index: 24.2600
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.8249
Cell Significance Index: 104.1100
Cell Name: odontoblast (CL0000060)
Fold Change: 3.3184
Cell Significance Index: 425.4000
Cell Name: neoplastic cell (CL0001063)
Fold Change: 3.2832
Cell Significance Index: 651.5700
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 3.2446
Cell Significance Index: 2455.9000
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.8883
Cell Significance Index: 34.9000
Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.7364
Cell Significance Index: 91.1700
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.7080
Cell Significance Index: 77.4200
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.8344
Cell Significance Index: 158.8000
Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6478
Cell Significance Index: 64.0800
Cell Name: germ cell (CL0000586)
Fold Change: 0.6437
Cell Significance Index: 4.8600
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.3570
Cell Significance Index: 261.7700
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2993
Cell Significance Index: 15.5500
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.2299
Cell Significance Index: 12.9000
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0831
Cell Significance Index: -61.5800
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0914
Cell Significance Index: -172.0700
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.1164
Cell Significance Index: -214.6200
Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.1468
Cell Significance Index: -225.9800
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.1847
Cell Significance Index: -251.1600
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1877
Cell Significance Index: -5.4100
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1958
Cell Significance Index: -110.4000
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.2209
Cell Significance Index: -137.9300
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.2311
Cell Significance Index: -37.5800
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.2311
Cell Significance Index: -82.9000
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2985
Cell Significance Index: -85.8900
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.3523
Cell Significance Index: -223.7500
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3646
Cell Significance Index: -22.4100
Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4236
Cell Significance Index: -48.3600
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.4801
Cell Significance Index: -101.1300
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.5247
Cell Significance Index: -238.1300
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.5268
Cell Significance Index: -105.6800
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7459
Cell Significance Index: -23.8900
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.8091
Cell Significance Index: -92.7000
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.9421
Cell Significance Index: -59.3800
Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -1.0025
Cell Significance Index: -109.0500
Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -1.0907
Cell Significance Index: -6.5900
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -1.1057
Cell Significance Index: -6.8700
Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.2691
Cell Significance Index: -21.2400
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.3469
Cell Significance Index: -33.6700
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.3490
Cell Significance Index: -106.8400
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.3983
Cell Significance Index: -96.7000
Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.4206
Cell Significance Index: -24.4900
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -1.6068
Cell Significance Index: -233.5600
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -2.4319
Cell Significance Index: -253.2200
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -2.8548
Cell Significance Index: -38.9500
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -2.8788
Cell Significance Index: -220.9200
Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -3.3749
Cell Significance Index: -206.9100
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -3.5166
Cell Significance Index: -236.4600
Cell Name: retinal rod cell (CL0000604)
Fold Change: -3.7456
Cell Significance Index: -44.6500
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -3.8062
Cell Significance Index: -82.4600
Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -4.2198
Cell Significance Index: -23.0100
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -4.5640
Cell Significance Index: -134.4300
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -4.6876
Cell Significance Index: -125.6100
Cell Name: paneth cell of colon (CL0009009)
Fold Change: -4.9636
Cell Significance Index: -74.3800
Cell Name: perivascular cell (CL4033054)
Fold Change: -4.9878
Cell Significance Index: -23.0300
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -5.0328
Cell Significance Index: -176.8500
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -5.6500
Cell Significance Index: -72.7600
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -5.7216
Cell Significance Index: -253.0800
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -5.8969
Cell Significance Index: -216.4700
Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -6.0299
Cell Significance Index: -50.6500
Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -6.3131
Cell Significance Index: -130.9600
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -6.6966
Cell Significance Index: -253.5900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** RPLP0 is a subunit of the large ribosomal subunit, which is responsible for protein synthesis. The gene encodes for a protein that is part of the lateral stalk of the 60S ribosomal subunit, playing a crucial role in the assembly and function of this subunit. RPLP0 is also involved in the regulation of translation, particularly in the context of cap-dependent translation initiation. The gene's expression is tightly regulated, and alterations in its expression have been linked to various diseases, including cancer and infectious diseases. **Pathways and Functions** RPLP0 is involved in various cellular processes, including: 1. **Translation**: RPLP0 is essential for the assembly and function of the large ribosomal subunit, which is responsible for protein synthesis. 2. **Ribosome Biogenesis**: RPLP0 is involved in the assembly of the large ribosomal subunit, which is critical for the production of ribosomes. 3. **Cytokine Signaling**: RPLP0 is involved in the signaling pathways of cytokines, including interleukin-12, which plays a crucial role in immune regulation. 4. **Viral Infection Pathways**: RPLP0 is involved in the translation of viral RNAs, particularly in the context of influenza infection. 5. **Immune Response**: RPLP0 is expressed in immune cells, including T cells and B cells, and is involved in the regulation of immune responses. **Clinical Significance** Altered expression of RPLP0 has been linked to various diseases, including: 1. **Cancer**: RPLP0 expression is altered in various types of cancer, including leukemia and lymphoma. 2. **Infectious Diseases**: RPLP0 expression is altered in response to viral infections, including influenza. 3. **Autoimmune Diseases**: RPLP0 expression is altered in autoimmune diseases, including multiple sclerosis. 4. **Neurological Disorders**: RPLP0 expression is altered in neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, RPLP0 is a critical gene involved in various cellular processes, including translation, ribosome biogenesis, and immune response. Its altered expression has been linked to various diseases, highlighting the importance of this gene in maintaining cellular homeostasis and immune regulation. Further research is needed to fully understand the mechanisms by which RPLP0 regulates cellular processes and its role in disease.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

60S acidic ribosomal protein P0

Genular Protein ID: 3994815924

Symbol: RLA0_HUMAN

Name: 60S acidic ribosomal protein P0

UniProtKB Accession Codes:

P05388 Q3B7A4 Q9BVK4

Database IDs:

Citations:

PubMed ID: 3323886

Title: Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly.

PubMed ID: 3323886

DOI: 10.1128/mcb.7.11.4065-4074.1987

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9582194

Title: A map of 75 human ribosomal protein genes.

PubMed ID: 9582194

DOI: 10.1101/gr.8.5.509

PubMed ID: 17289661

Title: Molecular composition of IMP1 ribonucleoprotein granules.

PubMed ID: 17289661

DOI: 10.1074/mcp.m600346-mcp200

PubMed ID: 19188445

Title: APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

PubMed ID: 19188445

DOI: 10.1128/mcb.01337-08

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24524803

Title: A new system for naming ribosomal proteins.

PubMed ID: 24524803

DOI: 10.1016/j.sbi.2014.01.002

PubMed ID: 24658146

Title: Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin.

PubMed ID: 24658146

DOI: 10.1371/journal.pone.0091465

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 36638793

Title: An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes.

PubMed ID: 36638793

DOI: 10.1016/j.cell.2022.12.025

PubMed ID: 23636399

Title: Structures of the human and Drosophila 80S ribosome.

PubMed ID: 23636399

DOI: 10.1038/nature12104

Sequence Information:

Length: 317
Mass: 34274
Checksum: 255AD25571C51199
Sequence:

MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM 
MRKAIRGHLE NNPALEKLLP HIRGNVGFVF TKEDLTEIRD MLLANKVPAA ARAGAIAPCE 
VTVPAQNTGL GPEKTSFFQA LGITTKISRG TIEILSDVQL IKTGDKVGAS EATLLNMLNI 
SPFSFGLVIQ QVFDNGSIYN PEVLDITEET LHSRFLEGVR NVASVCLQIG YPTVASVPHS 
IINGYKRVLA LSVETDYTFP LAEKVKAFLA DPSAFVAAAP VAAATTAAPA AAAAPAKVEA 
KEESEESDED MGFGLFD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: RPLP0

Associated with

Cells (max top 100)

Other Information

Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. PubMed ID: 3323886

The finished DNA sequence of human chromosome 12. PubMed ID: 16541075

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A map of 75 human ribosomal protein genes. PubMed ID: 9582194

Molecular composition of IMP1 ribonucleoprotein granules. PubMed ID: 17289661

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. PubMed ID: 19188445

Large-scale proteomics analysis of the human kinome. PubMed ID: 19369195

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

A new system for naming ribosomal proteins. PubMed ID: 24524803

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin. PubMed ID: 24658146

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli. PubMed ID: 25114211

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes. PubMed ID: 36638793

Structures of the human and Drosophila 80S ribosome. PubMed ID: 23636399