Details for: SFRP2

Gene ID: 6423

Symbol: SFRP2

Ensembl ID: ENSG00000145423

Description: secreted frizzled related protein 2

Associated with

  • Negative regulation of tcf-dependent signaling by wnt ligand antagonists
    (R-HSA-3772470)
  • Signaling by wnt
    (R-HSA-195721)
  • Signal transduction
    (R-HSA-162582)
  • Tcf dependent signaling in response to wnt
    (R-HSA-201681)
  • Bmp signaling pathway
    (GO:0030509)
  • Branching involved in blood vessel morphogenesis
    (GO:0001569)
  • Canonical wnt signaling pathway
    (GO:0060070)
  • Cardiac left ventricle morphogenesis
    (GO:0003214)
  • Cardiac muscle cell apoptotic process
    (GO:0010659)
  • Cell-cell signaling
    (GO:0007267)
  • Cellular response to x-ray
    (GO:0071481)
  • Chondrocyte development
    (GO:0002063)
  • Collagen-containing extracellular matrix
    (GO:0062023)
  • Collagen fibril organization
    (GO:0030199)
  • Convergent extension involved in axis elongation
    (GO:0060028)
  • Digestive tract morphogenesis
    (GO:0048546)
  • Embryonic digit morphogenesis
    (GO:0042733)
  • Endopeptidase activator activity
    (GO:0061133)
  • Extracellular space
    (GO:0005615)
  • Fibronectin binding
    (GO:0001968)
  • Hematopoietic stem cell proliferation
    (GO:0071425)
  • Integrin binding
    (GO:0005178)
  • Male gonad development
    (GO:0008584)
  • Mesodermal cell fate specification
    (GO:0007501)
  • Negative regulation of bmp signaling pathway
    (GO:0030514)
  • Negative regulation of canonical wnt signaling pathway
    (GO:0090090)
  • Negative regulation of cardiac muscle cell apoptotic process
    (GO:0010667)
  • Negative regulation of cell growth
    (GO:0030308)
  • Negative regulation of cell migration
    (GO:0030336)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of dermatome development
    (GO:0061185)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of epithelial cell proliferation
    (GO:0050680)
  • Negative regulation of epithelial to mesenchymal transition
    (GO:0010719)
  • Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
    (GO:1902042)
  • Negative regulation of gene expression
    (GO:0010629)
  • Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage
    (GO:1902230)
  • Negative regulation of mesodermal cell fate specification
    (GO:0042662)
  • Negative regulation of peptidyl-tyrosine phosphorylation
    (GO:0050732)
  • Negative regulation of wnt signaling pathway
    (GO:0030178)
  • Non-canonical wnt signaling pathway
    (GO:0035567)
  • Outflow tract morphogenesis
    (GO:0003151)
  • Positive regulation of angiogenesis
    (GO:0045766)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of canonical wnt signaling pathway
    (GO:0090263)
  • Positive regulation of cell adhesion mediated by integrin
    (GO:0033630)
  • Positive regulation of cell growth
    (GO:0030307)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of fat cell differentiation
    (GO:0045600)
  • Positive regulation of osteoblast differentiation
    (GO:0045669)
  • Positive regulation of peptidyl-serine phosphorylation
    (GO:0033138)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Post-anal tail morphogenesis
    (GO:0036342)
  • Receptor ligand activity
    (GO:0048018)
  • Regulation of midbrain dopaminergic neuron differentiation
    (GO:1904956)
  • Regulation of neuron projection development
    (GO:0010975)
  • Regulation of stem cell division
    (GO:2000035)
  • Response to nutrient
    (GO:0007584)
  • Response to xenobiotic stimulus
    (GO:0009410)
  • Sclerotome development
    (GO:0061056)
  • Stem cell fate specification
    (GO:0048866)
  • Wnt-protein binding
    (GO:0017147)
  • Wnt signaling pathway involved in somitogenesis
    (GO:0090244)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 8.6819
    Cell Significance Index: 49.7800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 6.1704
    Cell Significance Index: 176.8800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 4.7622
    Cell Significance Index: 99.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.6576
    Cell Significance Index: 205.2500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.8853
    Cell Significance Index: 44.6400
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.8648
    Cell Significance Index: 16.1300
  • Cell Name: chondroblast (CL0000058)
    Fold Change: 1.7138
    Cell Significance Index: 10.0600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.6801
    Cell Significance Index: 32.7900
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.6675
    Cell Significance Index: 8.1100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.3389
    Cell Significance Index: 28.6200
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: 1.2051
    Cell Significance Index: 6.8500
  • Cell Name: muscle fibroblast (CL1001609)
    Fold Change: 0.7803
    Cell Significance Index: 4.7800
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.7022
    Cell Significance Index: 6.7700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.5235
    Cell Significance Index: 15.4200
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.4599
    Cell Significance Index: 5.0000
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.4352
    Cell Significance Index: 1.0100
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.3490
    Cell Significance Index: 2.6400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2636
    Cell Significance Index: 30.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2097
    Cell Significance Index: 5.5200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1850
    Cell Significance Index: 66.3600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.1574
    Cell Significance Index: 2.6400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 0.1045
    Cell Significance Index: 0.6200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0190
    Cell Significance Index: 29.1900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0142
    Cell Significance Index: 26.2400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0033
    Cell Significance Index: 0.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0004
    Cell Significance Index: 0.2700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0005
    Cell Significance Index: -0.0700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0072
    Cell Significance Index: -5.3700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0087
    Cell Significance Index: -11.8200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0089
    Cell Significance Index: -5.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0101
    Cell Significance Index: -18.9700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0136
    Cell Significance Index: -9.4200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0165
    Cell Significance Index: -9.2800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0171
    Cell Significance Index: -12.5700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0203
    Cell Significance Index: -15.3400
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0334
    Cell Significance Index: -0.2100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0336
    Cell Significance Index: -3.4300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0359
    Cell Significance Index: -19.5800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0371
    Cell Significance Index: -1.2900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0392
    Cell Significance Index: -17.8000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0409
    Cell Significance Index: -11.7700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0424
    Cell Significance Index: -1.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0506
    Cell Significance Index: -10.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0520
    Cell Significance Index: -8.8800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0539
    Cell Significance Index: -11.3600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0577
    Cell Significance Index: -7.4500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0604
    Cell Significance Index: -3.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0804
    Cell Significance Index: -15.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0943
    Cell Significance Index: -4.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0980
    Cell Significance Index: -14.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1027
    Cell Significance Index: -2.8700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1054
    Cell Significance Index: -12.9600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1314
    Cell Significance Index: -2.0900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1338
    Cell Significance Index: -15.7800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1342
    Cell Significance Index: -10.0000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1379
    Cell Significance Index: -16.0700
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: -0.1519
    Cell Significance Index: -1.4100
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.1542
    Cell Significance Index: -0.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1565
    Cell Significance Index: -21.4900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1879
    Cell Significance Index: -19.5600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1902
    Cell Significance Index: -21.7900
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.2127
    Cell Significance Index: -3.2300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2161
    Cell Significance Index: -5.5200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2218
    Cell Significance Index: -2.8400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2328
    Cell Significance Index: -11.7600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2347
    Cell Significance Index: -15.7800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2492
    Cell Significance Index: -12.9800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2520
    Cell Significance Index: -15.8800
  • Cell Name: articular chondrocyte (CL1001607)
    Fold Change: -0.2934
    Cell Significance Index: -1.5900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3072
    Cell Significance Index: -23.5800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3127
    Cell Significance Index: -14.5800
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.3249
    Cell Significance Index: -3.1800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3297
    Cell Significance Index: -3.7500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.3424
    Cell Significance Index: -2.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3651
    Cell Significance Index: -16.1500
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.3738
    Cell Significance Index: -5.2500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4243
    Cell Significance Index: -17.3800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4297
    Cell Significance Index: -16.2700
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.4488
    Cell Significance Index: -2.3500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4548
    Cell Significance Index: -14.8900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4562
    Cell Significance Index: -15.9800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4593
    Cell Significance Index: -12.2900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4694
    Cell Significance Index: -24.6500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.4784
    Cell Significance Index: -24.8500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.5128
    Cell Significance Index: -8.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5311
    Cell Significance Index: -14.2300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5486
    Cell Significance Index: -17.3500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5596
    Cell Significance Index: -15.9700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.5633
    Cell Significance Index: -13.5100
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: -0.5648
    Cell Significance Index: -4.3100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.5706
    Cell Significance Index: -4.8500
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.5749
    Cell Significance Index: -4.5900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.5778
    Cell Significance Index: -21.2100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5904
    Cell Significance Index: -18.8100
  • Cell Name: peridermal cell (CL0000078)
    Fold Change: -0.6093
    Cell Significance Index: -3.8000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.6138
    Cell Significance Index: -15.3300
  • Cell Name: stromal cell (CL0000499)
    Fold Change: -0.6352
    Cell Significance Index: -6.4900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.6377
    Cell Significance Index: -13.3100
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.6438
    Cell Significance Index: -13.1000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.6440
    Cell Significance Index: -16.0600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SFRP2 is a secreted protein that belongs to the frizzled-related protein family. It is characterized by its ability to bind to Wnt proteins and other signaling molecules, modulating their activity. SFRP2 is expressed in various tissues, including the mammary gland, lung, liver, and heart, and is secreted by different cell types, including fibroblasts, inflammatory cells, and mesenchymal stem cells. Its expression is often upregulated in response to injury, inflammation, or tissue damage. **Pathways and Functions** SFRP2 is involved in various signaling pathways, including: 1. **Wnt/β-catenin pathway**: SFRP2 inhibits this pathway by binding to Wnt proteins and preventing their interaction with Frizzled receptors, thereby reducing β-catenin signaling and modulating cell growth and differentiation. 2. **BMP pathway**: SFRP2 negatively regulates BMP signaling by binding to BMP receptors and inhibiting their activation. 3. **Notch pathway**: SFRP2 modulates Notch signaling by interacting with Notch receptors and influencing their activation. 4. **Angiogenesis**: SFRP2 promotes angiogenesis by activating the VEGF signaling pathway and enhancing vascular endothelial cell proliferation and migration. 5. **Cell growth and differentiation**: SFRP2 regulates cell growth and differentiation by modulating the activity of various signaling pathways, including Wnt/β-catenin, BMP, and Notch. **Clinical Significance** Dysregulation of SFRP2 has been implicated in various diseases, including: 1. **Cancer**: Overexpression of SFRP2 has been observed in various types of cancer, including breast, lung, and colon cancer, and is associated with poor prognosis. 2. **Cardiovascular disease**: SFRP2 has been shown to play a role in cardiovascular disease, including atherosclerosis and cardiac hypertrophy. 3. **Inflammatory disorders**: SFRP2 has been implicated in inflammatory disorders, including arthritis and multiple sclerosis. 4. **Neurological disorders**: SFRP2 has been shown to play a role in neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, SFRP2 is a multifunctional protein that plays a crucial role in various signaling pathways, modulating cellular processes such as cell growth, differentiation, and survival. Its dysregulation has been implicated in various diseases, highlighting the importance of SFRP2 in maintaining tissue homeostasis and preventing disease.

Genular Protein ID: 3084787453

Symbol: SFRP2_HUMAN

Name: Secreted frizzled-related protein 2

UniProtKB Accession Codes:

Q96HF1 B3KQR2 O14778 Q9HAP5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 62 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9642118

Title: Tissue restricted expression of two human Frzbs in preadipocytes and pancreas.

PubMed ID: 9642118

DOI: 10.1006/bbrc.1998.8784

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9391078

Title: SARPs: a family of secreted apoptosis-related proteins.

PubMed ID: 9391078

DOI: 10.1073/pnas.94.25.13636

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

Sequence Information:

  • Length: 295
  • Mass: 33490
  • Checksum: 97597971541BFBC4
  • Sequence:
    • MLQGPGSLLL LFLASHCCLG SARGLFLFGQ PDFSYKRSNC KPIPANLQLC HGIEYQNMRL 
PNLLGHETMK EVLEQAGAWI PLVMKQCHPD TKKFLCSLFA PVCLDDLDET IQPCHSLCVQ 
VKDRCAPVMS AFGFPWPDML ECDRFPQDND LCIPLASSDH LLPATEEAPK VCEACKNKND 
DDNDIMETLC KNDFALKIKV KEITYINRDT KIILETKSKT IYKLNGVSER DLKKSVLWLK 
DSLQCTCEEM NDINAPYLVM GQKQGGELVI TSVKRWQKGQ REFKRISRSI RKLQC

Genular Protein ID: 1785205343

Symbol: B3KSM5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KSM5

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 2 InterPro 6 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 238
  • Mass: 27239
  • Checksum: D925BA5E6BABE534
  • Sequence:
    • MRLPNLLGHE TMKEVLEQAG AWIPLVMKQC HPDTKKFLCS LFAPVCLDDL DETIQPCHSL 
CVQVKDRCAP VMSAFGFPWP DMLECDRFPQ DNDLCIPLAS SDHLLPATEE APKVCEACKN 
KNDDDNDIME TLCKNDFALK IKVKEITYIN RDTKIILETK SKTIYKLNGV SERDLKKSVL 
WLKDSLQCTC EEMNDINAPY LVMGQKQGGE LVITSVKRWQ KGQREFKRIS RSIRKLQC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.