Details for: SLC4A2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 105.0498
Cell Significance Index: -16.3400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 63.2384
Cell Significance Index: -16.0400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 34.7809
Cell Significance Index: -14.1300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 14.9150
Cell Significance Index: -14.2400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.6501
Cell Significance Index: -16.8300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.8644
Cell Significance Index: -15.7100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.2980
Cell Significance Index: -16.9600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.1023
Cell Significance Index: -12.6000 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.1664
Cell Significance Index: -6.9300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 1.6007
Cell Significance Index: 186.5400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.4050
Cell Significance Index: 19.1700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.0018
Cell Significance Index: 108.9700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9017
Cell Significance Index: 146.6600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.7103
Cell Significance Index: 37.0000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.6359
Cell Significance Index: 16.9800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.5793
Cell Significance Index: 16.1900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5752
Cell Significance Index: 26.0700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5368
Cell Significance Index: 15.4700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4519
Cell Significance Index: 89.6900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3945
Cell Significance Index: 27.2800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3904
Cell Significance Index: 38.6200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.3878
Cell Significance Index: 10.3900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3582
Cell Significance Index: 7.7600 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.3522
Cell Significance Index: 4.9400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.3438
Cell Significance Index: 9.0400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3084
Cell Significance Index: 55.6000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3064
Cell Significance Index: 37.6800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3028
Cell Significance Index: 165.3800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2946
Cell Significance Index: 37.7600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2944
Cell Significance Index: 265.8400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2789
Cell Significance Index: 14.4900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2647
Cell Significance Index: 36.3600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2172
Cell Significance Index: 41.3400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2160
Cell Significance Index: 10.0700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1616
Cell Significance Index: 7.6000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1197
Cell Significance Index: 7.7200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1061
Cell Significance Index: 2.2600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0894
Cell Significance Index: 3.1400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0844
Cell Significance Index: 14.4200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0786
Cell Significance Index: 34.7300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0684
Cell Significance Index: 128.8100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.0651
Cell Significance Index: 1.3500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0472
Cell Significance Index: 3.5200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0422
Cell Significance Index: 3.2400 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.0324
Cell Significance Index: 0.4500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0314
Cell Significance Index: 0.9000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0232
Cell Significance Index: 1.4600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0204
Cell Significance Index: 14.9500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0155
Cell Significance Index: 11.7100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0144
Cell Significance Index: 9.9400 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0130
Cell Significance Index: 1.6800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0097
Cell Significance Index: 0.4900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0040
Cell Significance Index: 7.3900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0018
Cell Significance Index: 1.1300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0011
Cell Significance Index: 0.0300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0010
Cell Significance Index: -1.5100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0025
Cell Significance Index: -0.3700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0070
Cell Significance Index: -9.5700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0117
Cell Significance Index: -1.3800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0137
Cell Significance Index: -6.2000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0153
Cell Significance Index: -11.3700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0203
Cell Significance Index: -7.2900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0226
Cell Significance Index: -1.6000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0229
Cell Significance Index: -2.3400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0274
Cell Significance Index: -15.4300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0306
Cell Significance Index: -19.1000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0311
Cell Significance Index: -0.5200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0470
Cell Significance Index: -13.5100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0509
Cell Significance Index: -10.2100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0558
Cell Significance Index: -6.3900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0889
Cell Significance Index: -18.7400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1194
Cell Significance Index: -6.2700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1199
Cell Significance Index: -12.4800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.1277
Cell Significance Index: -2.3600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1477
Cell Significance Index: -1.3600 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.1563
Cell Significance Index: -2.4800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1580
Cell Significance Index: -5.0600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1620
Cell Significance Index: -9.0900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1659
Cell Significance Index: -13.1400 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1660
Cell Significance Index: -5.7700 - Cell Name: kidney cell (CL1000497)
Fold Change: -0.1716
Cell Significance Index: -1.3700 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.1856
Cell Significance Index: -1.2100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2013
Cell Significance Index: -12.3700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2351
Cell Significance Index: -14.4200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.2408
Cell Significance Index: -5.0400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2644
Cell Significance Index: -17.7800 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.2765
Cell Significance Index: -3.8800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.2855
Cell Significance Index: -2.9600 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2898
Cell Significance Index: -4.1500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2906
Cell Significance Index: -8.5400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3122
Cell Significance Index: -8.0300 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.3237
Cell Significance Index: -13.2600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3595
Cell Significance Index: -10.5900 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: -0.3607
Cell Significance Index: -3.8800 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.3622
Cell Significance Index: -3.4400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3652
Cell Significance Index: -9.3300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.3709
Cell Significance Index: -8.5700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.3744
Cell Significance Index: -9.3600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3776
Cell Significance Index: -13.8600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3823
Cell Significance Index: -16.9100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1209439920
Symbol: B3A2_HUMAN
Name: Anion exchange protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1562608
Title: Complete nucleotide sequence of band 3 related anion transport protein AE2 from human kidney.
PubMed ID: 1562608
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3015590
Title: Cloning and structural characterization of a human non-erythroid band 3-like protein.
PubMed ID: 3015590
PubMed ID: 10623603
Title: Tissue-specific N-terminal isoforms from overlapping alternate promoters of the human AE2 anion exchanger gene.
PubMed ID: 10623603
PubMed ID: 15184086
Title: Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes.
PubMed ID: 15184086
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 34668226
Title: SLC4A2 Deficiency Causes a New Type of Osteopetrosis.
PubMed ID: 34668226
DOI: 10.1002/jbmr.4462
Sequence Information:
- Length: 1241
- Mass: 137009
- Checksum: 35E32D9FC34DFB61
- Sequence:
MSSAPRRPAK GADSFCTPEP ESLGPGTPGF PEQEEDELHR TLGVERFEEI LQEAGSRGGE EPGRSYGEED FEYHRQSSHH IHHPLSTHLP PDARRRKTPQ GPGRKPRRRP GASPTGETPT IEEGEEDEDE ASEAEGARAL TQPSPVSTPS SVQFFLQEDD SADRKAERTS PSSPAPLPHQ EATPRASKGA QAGTQVEEAE AEAVAVASGT AGGDDGGASG RPLPKAQPGH RSYNLQERRR IGSMTGAEQA LLPRVPTDEI EAQTLATADL DLMKSHRFED VPGVRRHLVR KNAKGSTQSG REGREPGPTP RARPRAPHKP HEVFVELNEL LLDKNQEPQW RETARWIKFE EDVEEETERW GKPHVASLSF RSLLELRRTL AHGAVLLDLD QQTLPGVAHQ VVEQMVISDQ IKAEDRANVL RALLLKHSHP SDEKDFSFPR NISAGSLGSL LGHHHGQGAE SDPHVTEPLM GGVPETRLEV ERERELPPPA PPAGITRSKS KHELKLLEKI PENAEATVVL VGCVEFLSRP TMAFVRLREA VELDAVLEVP VPVRFLFLLL GPSSANMDYH EIGRSISTLM SDKQFHEAAY LADEREDLLT AINAFLDCSV VLPPSEVQGE ELLRSVAHFQ RQMLKKREEQ GRLLPTGAGL EPKSAQDKAL LQMVEAAGAA EDDPLRRTGR PFGGLIRDVR RRYPHYLSDF RDALDPQCLA AVIFIYFAAL SPAITFGGLL GEKTQDLIGV SELIMSTALQ GVVFCLLGAQ PLLVIGFSGP LLVFEEAFFS FCSSNHLEYL VGRVWIGFWL VFLALLMVAL EGSFLVRFVS RFTQEIFAFL ISLIFIYETF YKLVKIFQEH PLHGCSASNS SEVDGGENMT WAGARPTLGP GNRSLAGQSG QGKPRGQPNT ALLSLVLMAG TFFIAFFLRK FKNSRFFPGR IRRVIGDFGV PIAILIMVLV DYSIEDTYTQ KLSVPSGFSV TAPEKRGWVI NPLGEKSPFP VWMMVASLLP AILVFILIFM ETQITTLIIS KKERMLQKGS GFHLDLLLIV AMGGICALFG LPWLAAATVR SVTHANALTV MSKAVAPGDK PKIQEVKEQR VTGLLVALLV GLSIVIGDLL RQIPLAVLFG IFLYMGVTSL NGIQFYERLH LLLMPPKHHP DVTYVKKVRT LRMHLFTALQ LLCLALLWAV MSTAASLAFP FILILTVPLR MVVLTRIFTD REMKCLDANE AEPVFDEREG VDEYNEMPMP V
Genular Protein ID: 4222593767
Symbol: Q59GF1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1244
- Mass: 137283
- Checksum: C43A5BDB38C1F8D2
- Sequence:
DSAMSSAPRR PAKGADSFCT PEPESLGPGT PGFPEQEEDE LHRTLGVERF EEILQEAGSR GGEEPGRSYG EEDFEYHRQS SHHIHHPLST HLPPDARRRK TPQGPGRKPR RRPGASPTGE TPTIEEGEED EDEASEAEGA RALTQPSPVS TPSSVQFFLQ EDDSADRKAE RTSPSSPAPL PHQEATPRAS KGAQAGTQVE EAEAEAVAVA SGTAGGDDGG ASGRPLPKAQ PGHRSYNLQE RRRIGSMTGA EQALLPRVPT DEIEAQTLAT ADLDLMKSHR FEDVPGVRRH LVRKNAKGST QSGREGREPG PTPRARPRAP HKPHEVFVEL NELLLDKNQE PQWRETARWI KFEEDVEEET ERWGKPHVAS LSFRSLLELR RTLAHGAVLL DLDQQTLPGV AHQVVEQMVI SDQIKAEDRA NVLRALLLKH SHPSDEKDFS FPRNISAGSL GSLLGHHHGQ GAESDPHVTE PLMGGVPETR LEVERERELP PPAPPAGITR SKSKHELKLL EKIPENAEAT VVLVGCVEFL SRPTMAFVRL REAVELDAVL EVPVPVRFLF LLLGPSSANM DYHEIGRSIS TLMSDKQFHE AAYLADERED LLTAINAFLD CSVVLPPSEV QGEELLRSVA HFQRQMLKKR EEQGRLLPTG AGLEPKSAQD KALLQMVEAA GAAEDDPLRR TGRPFGGLIR DVRRRYPHYL SDFRDALDPQ CLAAVIFIYF AALSPAITFG GLLGEKTQDL IGVSELIMST ALQGVVFCLL GAQPLLVIGF SGPLLVFEEA FFSFCSSNHL EYLVGRVWIG FWLVFLALLM VALEGSFLVR FVSRFTQEIF AFLISLIFIY ETFYKLVKIF QEHPLHGCSA SNSSEVDGGE NMTWAGARPT LGPGNRSLAG QSGQGKPRGQ PNTALLSLVL MAGTFFIAFF LRKFKNSRFF PGRIRRVIGD FGVPIAILIM VLVDYSIEDT YTQKLSVPSG FSVTAPEKRG WVINPLGEKS PFPVWMMVAS LLPAILVFIL IFMETQITTL IISKKERMLQ KGSGFHLDLL LIVAMGGICA LFGLPWLAAA TVRSVTHANA LTVMSKAVAP GDKPKIQEVK EQRVTGLLVA LLVGLSIVIG DLLRQIPLAV LFGIFLYMGV TSLNGIQFYE RLHLLLMPPK HHPDVTYVKK VRTLRMHLFT ALQLLCLALL WAVMSTAASL AFPFILILTV PLRMVVLTRI FTDREMKCLD ANEAEPVFDE REGVDEYNEM PMPV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.