Details for: SLC25A1

Gene ID: 6576

Symbol: SLC25A1

Ensembl ID: ENSG00000100075

Description: solute carrier family 25 member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 146.1954
    Cell Significance Index: -22.7400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 86.8937
    Cell Significance Index: -22.0400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 56.3436
    Cell Significance Index: -22.8900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 55.6211
    Cell Significance Index: -26.2600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 51.2262
    Cell Significance Index: -26.3500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 39.3430
    Cell Significance Index: -26.4000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 24.1845
    Cell Significance Index: -23.0900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.8547
    Cell Significance Index: -24.4800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.8280
    Cell Significance Index: -20.9700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.2772
    Cell Significance Index: -24.7700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.6260
    Cell Significance Index: -17.2800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.8110
    Cell Significance Index: 168.7600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.0426
    Cell Significance Index: 18.8100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.5033
    Cell Significance Index: 20.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.3941
    Cell Significance Index: 63.1900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.1643
    Cell Significance Index: 24.3700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1428
    Cell Significance Index: 185.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0724
    Cell Significance Index: 585.6800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0570
    Cell Significance Index: 114.9700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.9176
    Cell Significance Index: 13.7500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.9113
    Cell Significance Index: 112.0500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8803
    Cell Significance Index: 45.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8142
    Cell Significance Index: 146.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7476
    Cell Significance Index: 102.6700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.7457
    Cell Significance Index: 52.7400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7326
    Cell Significance Index: 145.3900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.7159
    Cell Significance Index: 16.5400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.7077
    Cell Significance Index: 83.4600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6835
    Cell Significance Index: 31.8700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6615
    Cell Significance Index: 125.8900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6121
    Cell Significance Index: 552.6600
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.5411
    Cell Significance Index: 6.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4942
    Cell Significance Index: 14.2400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4722
    Cell Significance Index: 208.7600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4583
    Cell Significance Index: 9.9300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.4423
    Cell Significance Index: 11.6300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4150
    Cell Significance Index: 26.7800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3914
    Cell Significance Index: 12.5400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3482
    Cell Significance Index: 16.3700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3028
    Cell Significance Index: 39.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2926
    Cell Significance Index: 10.2800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2816
    Cell Significance Index: 14.6700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2791
    Cell Significance Index: 20.8000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2671
    Cell Significance Index: 7.2700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2421
    Cell Significance Index: 5.1600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2379
    Cell Significance Index: 23.5300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1719
    Cell Significance Index: 34.4900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1347
    Cell Significance Index: 17.2700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0984
    Cell Significance Index: 3.4200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0977
    Cell Significance Index: 35.0600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0580
    Cell Significance Index: 1.6200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0196
    Cell Significance Index: 14.8400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0131
    Cell Significance Index: 0.3500
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.0121
    Cell Significance Index: 0.0800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0102
    Cell Significance Index: 0.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0088
    Cell Significance Index: 13.5600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0067
    Cell Significance Index: 9.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0026
    Cell Significance Index: 0.4500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0026
    Cell Significance Index: 4.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0012
    Cell Significance Index: 0.8800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0037
    Cell Significance Index: -6.7500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0209
    Cell Significance Index: -13.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0210
    Cell Significance Index: -15.5500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0306
    Cell Significance Index: -3.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0309
    Cell Significance Index: -3.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0350
    Cell Significance Index: -19.7600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0427
    Cell Significance Index: -26.6900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0475
    Cell Significance Index: -21.5500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0649
    Cell Significance Index: -3.4100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0905
    Cell Significance Index: -26.0500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1164
    Cell Significance Index: -1.2100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1178
    Cell Significance Index: -17.1200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1272
    Cell Significance Index: -26.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1324
    Cell Significance Index: -15.4300
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.1685
    Cell Significance Index: -1.7000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1815
    Cell Significance Index: -4.8600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2083
    Cell Significance Index: -16.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2116
    Cell Significance Index: -13.0100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2322
    Cell Significance Index: -24.1800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.2465
    Cell Significance Index: -2.6800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2597
    Cell Significance Index: -4.8000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2672
    Cell Significance Index: -8.4500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2736
    Cell Significance Index: -18.4000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2901
    Cell Significance Index: -22.2600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2925
    Cell Significance Index: -8.5900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2975
    Cell Significance Index: -7.6000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3006
    Cell Significance Index: -16.8700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3090
    Cell Significance Index: -2.5200
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.3198
    Cell Significance Index: -2.4200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3375
    Cell Significance Index: -9.9400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3500
    Cell Significance Index: -5.9000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3588
    Cell Significance Index: -8.9700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3592
    Cell Significance Index: -22.0200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3684
    Cell Significance Index: -23.2200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.4095
    Cell Significance Index: -3.4400
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4375
    Cell Significance Index: -4.9700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4692
    Cell Significance Index: -7.0700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4727
    Cell Significance Index: -12.1500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4743
    Cell Significance Index: -7.0000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.5000
    Cell Significance Index: -8.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Mitochondrial citrate transmembrane transporter:** SLC25A1 encodes for a protein that transports citrate across the mitochondrial inner membrane, facilitating the exchange of energy-rich citrate with other metabolites. 2. **Antiporter activity:** This gene exhibits antiporter activity, allowing for the exchange of citrate with other ions, such as ATP, ADP, and Pi. 3. **Secondary active transport:** SLC25A1 functions as a secondary active transporter, relying on the concentration gradient of citrate to drive its transport across the mitochondrial inner membrane. 4. **Expression in various cell types:** SLC25A1 is expressed in extravillous trophoblast, germ cell, tracheobronchial smooth muscle cell, colon epithelial cell, enterocyte, epicardial adipocyte, and placental villous trophoblast, indicating its widespread importance in different tissues. **Pathways and Functions:** 1. **Gluconeogenesis:** SLC25A1 plays a critical role in gluconeogenesis, the process of generating glucose from non-carbohydrate sources, by facilitating the transport of citrate across the mitochondrial inner membrane. 2. **Glycolysis:** The gene is also involved in glycolysis, the breakdown of glucose to produce energy, by regulating the transport of citrate and other metabolites. 3. **Fatty acid metabolism:** SLC25A1 contributes to fatty acid metabolism by facilitating the transport of citrate, which is essential for the synthesis and oxidation of fatty acids. 4. **Mitochondrial function:** The gene is essential for the proper functioning of the mitochondrial inner membrane, allowing for the efficient transport of citrate and other metabolites. **Clinical Significance:** 1. **Metabolic disorders:** Alterations in SLC25A1 expression have been linked to various metabolic disorders, including diabetes, obesity, and fatty liver disease. 2. **Cancer:** The gene has been implicated in cancer development and progression, particularly in the context of mitochondrial dysfunction and altered energy metabolism. 3. **Pregnancy complications:** SLC25A1 expression in placental villous trophoblast has been linked to pregnancy complications, such as preeclampsia and fetal growth restriction. 4. **Neurological disorders:** The gene's role in energy metabolism and mitochondrial function suggests its potential involvement in neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, SLC25A1 is a critical gene that plays a pivotal role in various metabolic pathways, including gluconeogenesis, glycolysis, fatty acid metabolism, and mitochondrial function. Its dysregulation has been linked to various clinical disorders, highlighting the importance of this gene in maintaining energy homeostasis and overall health. Further research is necessary to fully elucidate the mechanisms by which SLC25A1 regulates metabolic pathways and to explore its therapeutic potential in the treatment of metabolic and neurological disorders.

Genular Protein ID: 178463187

Symbol: TXTP_HUMAN

Name: Tricarboxylate transport protein, mitochondrial

UniProtKB Accession Codes:

P53007 A8K8E8 Q9BSK6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 2 CTD 1 ChEBI 14 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 6 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 7 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8666394

Title: Localization of the human mitochondrial citrate transporter protein gene to chromosome 22q11 in the DiGeorge syndrome critical region.

PubMed ID: 8666394

DOI: 10.1006/geno.1995.9982

PubMed ID: 8660975

Title: Cloning, genomic organization, and chromosomal localization of human citrate transport protein to the DiGeorge/velocardiofacial syndrome minimal critical region.

PubMed ID: 8660975

DOI: 10.1006/geno.1996.0191

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26870663

Title: Mutations in the mitochondrial citrate carrier SLC25A1 are associated with impaired neuromuscular transmission.

PubMed ID: 26870663

DOI: 10.3233/jnd-140021

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29031613

Title: Pathogenic mutations of the human mitochondrial citrate carrier SLC25A1 lead to impaired citrate export required for lipid, dolichol, ubiquinone and sterol synthesis.

PubMed ID: 29031613

DOI: 10.1016/j.bbabio.2017.10.002

PubMed ID: 29238895

Title: An overview of combined D-2- and L-2-hydroxyglutaric aciduria: functional analysis of CIC variants.

PubMed ID: 29238895

DOI: 10.1007/s10545-017-0106-7

PubMed ID: 23561848

Title: Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria.

PubMed ID: 23561848

DOI: 10.1016/j.ajhg.2013.03.009

PubMed ID: 23393310

Title: Agenesis of corpus callosum and optic nerve hypoplasia due to mutations in SLC25A1 encoding the mitochondrial citrate transporter.

PubMed ID: 23393310

DOI: 10.1136/jmedgenet-2012-101485

PubMed ID: 25614306

Title: Expanding the clinical spectrum of mitochondrial citrate carrier (SLC25A1) deficiency: Facial dysmorphism in siblings with epileptic encephalopathy and combined D,L-2-hydroxyglutaric aciduria.

PubMed ID: 25614306

DOI: 10.1007/8904_2014_378

PubMed ID: 27306203

Title: Severe neonatal presentation of mitochondrial citrate carrier (SLC25A1) deficiency.

PubMed ID: 27306203

DOI: 10.1007/8904_2016_536

PubMed ID: 29226520

Title: A novel homozygous SLC25A1 mutation with impaired mitochondrial complex V: Possible phenotypic expansion.

PubMed ID: 29226520

DOI: 10.1002/ajmg.a.38574

Sequence Information:

  • Length: 311
  • Mass: 34013
  • Checksum: F1341629924953D6
  • Sequence:
    • MPAPRAPRAL AAAAPASGKA KLTHPGKAIL AGGLAGGIEI CITFPTEYVK TQLQLDERSH 
PPRYRGIGDC VRQTVRSHGV LGLYRGLSSL LYGSIPKAAV RFGMFEFLSN HMRDAQGRLD 
STRGLLCGLG AGVAEAVVVV CPMETIKVKF IHDQTSPNPK YRGFFHGVRE IVREQGLKGT 
YQGLTATVLK QGSNQAIRFF VMTSLRNWYR GDNPNKPMNP LITGVFGAIA GAASVFGNTP 
LDVIKTRMQG LEAHKYRNTW DCGLQILKKE GLKAFYKGTV PRLGRVCLDV AIVFVIYDEV 
VKLLNKVWKT D

Genular Protein ID: 16124159

Symbol: D9HTE9_HUMAN

Name: N/A

UniProtKB Accession Codes:

D9HTE9

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 14 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 IntAct 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 7 RuleBase 1 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 20448665

Title: Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells.

PubMed ID: 20448665

DOI: 10.1038/embor.2010.51

Sequence Information:

  • Length: 318
  • Mass: 35053
  • Checksum: FD9F3D072221AFD8
  • Sequence:
    • MFPAALARRP RRPKSGTGEG PERQRPGGSL RSGFPVPAGG LAGGIEICIT FPTEYVKTQL 
QLDERSHPPR YRGIGDCVRQ TVRSHGVLGL YRGLSSLLYG SIPKAAVRFG MFEFLSNHMR 
DAQGRLDSTR GLLCGLGAGV AEAVVVVCPM ETIKVKFIHD QTSPNPKYRG FFHGVREIVR 
EQGLKGTYQG LTATVLKQGS NQAIRFFVMT SLRNWYRGDN PNKPMNPLIT GVFGAIAGAA 
SVFGNTPLDV IKTRMQGLEA HKYRNTWDCG LQILKKEGLK AFYKGTVPRL GRVCLDVAIV 
FVIYDEVVKL LNKVWKTD

Genular Protein ID: 3589460716

Symbol: D3DX16_HUMAN

Name: N/A

UniProtKB Accession Codes:

D3DX16

Database IDs:

ARBA 13 CTD 1 ChEBI 14 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 2 GO 2 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 7 RuleBase 1 SUPFAM 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 208
  • Mass: 23210
  • Checksum: 121E6D75CD9D5C91
  • Sequence:
    • MFEFLSNHMR DAQGRLDSTR GLLCGLGAGV AEAVVVVCPM ETIKVKFIHD QTSPNPKYRG 
FFHGVREIVR EQGLKGTYQG LTATVLKQGS NQAIRFFVMT SLRNWYRGDN PNKPMNPLIT 
GVFGAIAGAA SVFGNTPLDV IKTRMQGLEA HKYRNTWDCG LQILKKEGLK AFYKGTVPRL 
GRVCLDVAIV FVIYDEVVKL LNKVWKTD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.