Details for: FSCN1

Gene ID: 6624

Symbol: FSCN1

Ensembl ID: ENSG00000075618

Description: fascin actin-bundling protein 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 2.97
    Marker Score: 17622
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.61
    Marker Score: 2789
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.57
    Marker Score: 2415
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 2.49
    Marker Score: 2792
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.42
    Marker Score: 6592
  • Cell Name: Unknown (CL0002371)
    Fold Change: 2.42
    Marker Score: 2570
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.39
    Marker Score: 1498.5
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 2.37
    Marker Score: 2855
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.35
    Marker Score: 15281
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.26
    Marker Score: 29817
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 2.16
    Marker Score: 1189
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.13
    Marker Score: 18676
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.1
    Marker Score: 4388
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.06
    Marker Score: 20759
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.97
    Marker Score: 2778
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 1.95
    Marker Score: 795
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.94
    Marker Score: 1823
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.92
    Marker Score: 1085
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.86
    Marker Score: 3162
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 1.78
    Marker Score: 840
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 1.77
    Marker Score: 1052
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.77
    Marker Score: 429
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.75
    Marker Score: 588
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 1.72
    Marker Score: 488
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.61
    Marker Score: 3266
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 1.55
    Marker Score: 525
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 1.5
    Marker Score: 1016
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.44
    Marker Score: 958
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.41
    Marker Score: 5211
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.32
    Marker Score: 5525
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.32
    Marker Score: 1600
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 1.31
    Marker Score: 652
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.29
    Marker Score: 301
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 1.29
    Marker Score: 17319
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.24
    Marker Score: 1171
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.23
    Marker Score: 13838
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 1.2
    Marker Score: 1730
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.15
    Marker Score: 6048
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.12
    Marker Score: 1837
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.12
    Marker Score: 2272
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.11
    Marker Score: 2208
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.1
    Marker Score: 604
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.08
    Marker Score: 347
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.08
    Marker Score: 8400
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 1.07
    Marker Score: 1476
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.04
    Marker Score: 755
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251742
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.03
    Marker Score: 3972
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.01
    Marker Score: 1561
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.01
    Marker Score: 4133
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71761
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47986
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1
    Marker Score: 2384
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.99
    Marker Score: 619
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.98
    Marker Score: 1360
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30400
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.97
    Marker Score: 1050
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.97
    Marker Score: 1068
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 492
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 0.95
    Marker Score: 2421
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.95
    Marker Score: 1398
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.95
    Marker Score: 471
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2405
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 446
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.94
    Marker Score: 1161
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.94
    Marker Score: 842
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 0.92
    Marker Score: 828
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.91
    Marker Score: 319.5
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2719
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.89
    Marker Score: 431
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.88
    Marker Score: 659
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.88
    Marker Score: 582
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5292
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.87
    Marker Score: 314
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.87
    Marker Score: 4952
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.86
    Marker Score: 2026
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.85
    Marker Score: 854
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.82
    Marker Score: 859
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.82
    Marker Score: 1022
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.8
    Marker Score: 258
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.8
    Marker Score: 188
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 606
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.79
    Marker Score: 285
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.79
    Marker Score: 12307
  • Cell Name: theca cell (CL0000503)
    Fold Change: 0.79
    Marker Score: 563
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.78
    Marker Score: 488.5
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1266
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.78
    Marker Score: 1002
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.77
    Marker Score: 1192
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.77
    Marker Score: 309
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.76
    Marker Score: 1846
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 0.76
    Marker Score: 402
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.75
    Marker Score: 3447
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.74
    Marker Score: 13211
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.74
    Marker Score: 678
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 382
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 0.73
    Marker Score: 486
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 0.73
    Marker Score: 175
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.72
    Marker Score: 1227
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.72
    Marker Score: 26670

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Other Information

**Key Characteristics:** FSCN1 is a member of the fascin family of actin-bundling proteins, which are characterized by their ability to cross-link actin filaments into bundles. FSCN1 is a homodimeric protein, consisting of two identical subunits, each containing six actin-binding domains. These domains are responsible for binding to actin filaments and facilitating the formation of actin bundles. FSCN1 is also characterized by its ability to bind to other proteins, including cadherins, which are involved in cell-cell adhesion and signaling. **Pathways and Functions:** FSCN1 plays a critical role in regulating the actin cytoskeleton organization and dynamics. It is involved in the formation of actin bundles, which are essential for maintaining cell shape, motility, and migration. FSCN1 also regulates the assembly of filopodia, lamellipodia, and microspikes, which are involved in cellular movement and migration. Additionally, FSCN1 interacts with other proteins, including cytokines and growth factors, to regulate immune responses and inflammation. Its expression is upregulated in cells undergoing stress, such as during wound healing and tissue injury. **Clinical Significance:** FSCN1 has been implicated in various diseases, including cancer, cardiovascular disease, and neurological disorders. In cancer, FSCN1 is overexpressed in many types of tumors, including breast, lung, and colon cancer, suggesting a potential role in tumor progression and metastasis. In cardiovascular disease, FSCN1 has been linked to atherosclerosis and cardiac hypertrophy. In neurological disorders, FSCN1 has been implicated in amyotrophic lateral sclerosis (ALS) and Alzheimer's disease. Furthermore, FSCN1 has been identified as a potential therapeutic target for the treatment of these diseases, as its inhibition has been shown to disrupt cellular migration and invasion. **Signaling Pathways:** FSCN1 interacts with various signaling pathways, including: 1. **Cytokine signaling**: FSCN1 regulates the signaling of cytokines, such as interleukin-4 and interleukin-13, which are involved in immune responses and inflammation. 2. **Extracellular matrix signaling**: FSCN1 interacts with extracellular matrix proteins, such as collagen and laminin, to regulate cell adhesion and migration. 3. **Growth factor signaling**: FSCN1 regulates the signaling of growth factors, such as epidermal growth factor (EGF) and fibroblast growth factor (FGF), which are involved in cellular proliferation and migration. **Conclusion:** FSCN1 is a critical regulator of actin cytoskeleton dynamics and cellular migration. Its expression is significantly upregulated in cells undergoing migration, suggesting a key role in cellular movement and disease progression. As an expert immunologist, I highlight the importance of FSCN1 in understanding the mechanisms of immune responses, inflammation, and disease. Further research is necessary to fully elucidate the role of FSCN1 in various diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 503411441

Symbol: FSCN1_HUMAN

Name: Fascin

UniProtKB Accession Codes:

Q16658 A6NI89 B2RE97 Q96IC5 Q96IH1 Q9BRF1

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 6 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 36 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 33 PDBsum 19 PIR 1 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8068206

Title: cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein.

PubMed ID: 8068206

DOI: 10.1089/dna.1994.13.821

PubMed ID: 7933116

Title: Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein.

PubMed ID: 7933116

DOI: 10.1128/jvi.68.11.7320-7328.1994

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3525578

Title: Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin.

PubMed ID: 3525578

DOI: 10.1083/jcb.103.2.631

PubMed ID: 8647875

Title: Phosphorylation of human fascin inhibits its actin binding and bundling activities.

PubMed ID: 8647875

DOI: 10.1074/jbc.271.21.12632

PubMed ID: 9362073

Title: Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes.

PubMed ID: 9362073

DOI: 10.1091/mbc.8.11.2345

PubMed ID: 9571235

Title: Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells.

PubMed ID: 9571235

DOI: 10.1091/mbc.9.5.993

PubMed ID: 8999969

Title: Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin.

PubMed ID: 8999969

DOI: 10.1074/jbc.272.4.2527

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20137952

Title: The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion.

PubMed ID: 20137952

DOI: 10.1016/j.cub.2009.12.035

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22155786

Title: Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

PubMed ID: 22155786

DOI: 10.1126/scisignal.2002060

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 21706053

Title: Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton.

PubMed ID: 21706053

DOI: 10.1038/onc.2011.256

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 20434460

Title: Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein.

PubMed ID: 20434460

DOI: 10.1016/j.jmb.2010.04.043

PubMed ID: 20393565

Title: Migrastatin analogues target fascin to block tumour metastasis.

PubMed ID: 20393565

DOI: 10.1038/nature08978

PubMed ID: 21685497

Title: Mechanism of actin filament bundling by fascin.

PubMed ID: 21685497

DOI: 10.1074/jbc.m111.251439

PubMed ID: 23184945

Title: Molecular mechanism of fascin function in filopodial formation.

PubMed ID: 23184945

DOI: 10.1074/jbc.m112.427971

Sequence Information:

  • Length: 493
  • Mass: 54530
  • Checksum: C1453714BED6109A
  • Sequence:
    • MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKQIWTLEQ PPDEAGSAAV 
CLRSHLGRYL AADKDGNVTC EREVPGPDCR FLIVAHDDGR WSLQSEAHRR YFGGTEDRLS 
CFAQTVSPAE KWSVHIAMHP QVNIYSVTRK RYAHLSARPA DEIAVDRDVP WGVDSLITLA 
FQDQRYSVQT ADHRFLRHDG RLVARPEPAT GYTLEFRSGK VAFRDCEGRY LAPSGPSGTL 
KAGKATKVGK DELFALEQSC AQVVLQAANE RNVSTRQGMD LSANQDEETD QETFQLEIDR 
DTKKCAFRTH TGKYWTLTAT GGVQSTASSK NASCYFDIEW RDRRITLRAS NGKFVTSKKN 
GQLAASVETA GDSELFLMKL INRPIIVFRG EHGFIGCRKV TGTLDANRSS YDVFQLEFND 
GAYNIKDSTG KYWTVGSDSA VTSSGDTPVD FFFEFCDYNK VAIKVGGRYL KGDHAGVLKA 
SAETVDPASL WEY

Genular Protein ID: 2651823769

Symbol: B3KTA3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KTA3

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 5 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 472
  • Mass: 52276
  • Checksum: 0316826D6A316DAC
  • Sequence:
    • MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKHLGRYLA ADKDGNVTCE 
REVPGPDCRF LIVAHDDGRW SLQSEAHRRY FGGTEDRLSC FAQTVSPAEK WSVHIAMHPQ 
VNIYSVTRKR YAHLSARPAD EIAVDRDVPW GVDSLITLAF QDQRYSVQTA DHRFLRHDGR 
LVARPEPATG YTLEFRSGKV AFRDCEGRYL APSGPSGTLK AGKATKVGKD ELFALEQSCA 
QVVLQAANER NVSTRQGMDL SANQDEETDQ ETFQLEIDRD TKKCAFRTHT GKYWTLTATG 
GVQSTASSKN ASCYFDIEWR DRRITLRASN GKFVTSKKNG QLAASVETAG DSELFLMKLI 
NRPIIVFRGE HGFIGCRKVT GTLDANRSSY DVFQLEFNDG AYNIKDSTGK YWTVGSDSAV 
TSSGDTPVDF FFEFCDYNKV AIKVGGRYLK GDHAGVLKAS AETVDPASLW EY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.