Details for: FSCN1

Gene ID: 6624

Symbol: FSCN1

Ensembl ID: ENSG00000075618

Description: fascin actin-bundling protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 273.3610
    Cell Significance Index: -42.5200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 151.2754
    Cell Significance Index: -38.3700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 98.1921
    Cell Significance Index: -40.4500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 93.8527
    Cell Significance Index: -44.3100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 85.1431
    Cell Significance Index: -34.5900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 36.6277
    Cell Significance Index: -34.9700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.0215
    Cell Significance Index: -43.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 16.3764
    Cell Significance Index: -43.8700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.0516
    Cell Significance Index: -43.6100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.7213
    Cell Significance Index: -32.9300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 5.8271
    Cell Significance Index: 121.9700
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 4.9238
    Cell Significance Index: 42.3100
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 4.8550
    Cell Significance Index: 52.7800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 4.7852
    Cell Significance Index: 67.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 4.0160
    Cell Significance Index: 105.6000
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 3.6899
    Cell Significance Index: 47.2600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.9419
    Cell Significance Index: 153.2400
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.6020
    Cell Significance Index: 12.6600
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 2.1304
    Cell Significance Index: 13.1800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 2.0048
    Cell Significance Index: 69.6700
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 0.9825
    Cell Significance Index: 16.8800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7975
    Cell Significance Index: 109.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7021
    Cell Significance Index: 36.4700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.6726
    Cell Significance Index: 86.2200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.6008
    Cell Significance Index: 77.6200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5353
    Cell Significance Index: 107.3800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.4252
    Cell Significance Index: 3.4000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.4070
    Cell Significance Index: 21.3700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3960
    Cell Significance Index: 175.1000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.3605
    Cell Significance Index: 9.2100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3205
    Cell Significance Index: 63.6000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3166
    Cell Significance Index: 172.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3014
    Cell Significance Index: 54.3300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2757
    Cell Significance Index: 33.9000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2613
    Cell Significance Index: 12.2800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2515
    Cell Significance Index: 11.4000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.2482
    Cell Significance Index: 2.8200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2204
    Cell Significance Index: 79.0400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1906
    Cell Significance Index: 172.0900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.1664
    Cell Significance Index: 2.6700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1663
    Cell Significance Index: 4.7900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1224
    Cell Significance Index: 4.3000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1128
    Cell Significance Index: 21.4600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1048
    Cell Significance Index: 6.4400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0951
    Cell Significance Index: 65.7500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0872
    Cell Significance Index: 1.4600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0458
    Cell Significance Index: 1.2800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0445
    Cell Significance Index: 7.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0422
    Cell Significance Index: 79.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0261
    Cell Significance Index: 2.5900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0081
    Cell Significance Index: -0.1100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0238
    Cell Significance Index: -36.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0240
    Cell Significance Index: -17.7900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0317
    Cell Significance Index: -58.4500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0395
    Cell Significance Index: -53.7800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0463
    Cell Significance Index: -0.2800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0475
    Cell Significance Index: -29.6600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0539
    Cell Significance Index: -39.5400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0545
    Cell Significance Index: -34.6400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0574
    Cell Significance Index: -43.4500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0704
    Cell Significance Index: -39.7300
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0898
    Cell Significance Index: -1.3900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0905
    Cell Significance Index: -9.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0922
    Cell Significance Index: -41.8300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1189
    Cell Significance Index: -34.2100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1206
    Cell Significance Index: -14.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1694
    Cell Significance Index: -35.6800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1967
    Cell Significance Index: -33.5900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2030
    Cell Significance Index: -11.3900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2449
    Cell Significance Index: -6.5500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2720
    Cell Significance Index: -39.5400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2725
    Cell Significance Index: -27.8400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2747
    Cell Significance Index: -7.3600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2820
    Cell Significance Index: -16.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2921
    Cell Significance Index: -33.4700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2979
    Cell Significance Index: -35.1300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3083
    Cell Significance Index: -35.1900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3089
    Cell Significance Index: -21.3700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3094
    Cell Significance Index: -19.9600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3611
    Cell Significance Index: -25.5400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3651
    Cell Significance Index: -7.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3837
    Cell Significance Index: -7.9600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4124
    Cell Significance Index: -42.9400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4140
    Cell Significance Index: -27.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4223
    Cell Significance Index: -25.8900
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.4296
    Cell Significance Index: -2.8000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4943
    Cell Significance Index: -36.8400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5119
    Cell Significance Index: -40.5400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5945
    Cell Significance Index: -19.0400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6111
    Cell Significance Index: -27.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6120
    Cell Significance Index: -46.9700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.6635
    Cell Significance Index: -11.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.7194
    Cell Significance Index: -17.9800
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.7398
    Cell Significance Index: -10.3700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.7668
    Cell Significance Index: -16.7900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7827
    Cell Significance Index: -29.6400
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.7868
    Cell Significance Index: -11.9500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.8011
    Cell Significance Index: -22.9700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.8092
    Cell Significance Index: -51.0000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.8460
    Cell Significance Index: -20.2900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** FSCN1 is a member of the fascin family of actin-bundling proteins, which are characterized by their ability to cross-link actin filaments into bundles. FSCN1 is a homodimeric protein, consisting of two identical subunits, each containing six actin-binding domains. These domains are responsible for binding to actin filaments and facilitating the formation of actin bundles. FSCN1 is also characterized by its ability to bind to other proteins, including cadherins, which are involved in cell-cell adhesion and signaling. **Pathways and Functions:** FSCN1 plays a critical role in regulating the actin cytoskeleton organization and dynamics. It is involved in the formation of actin bundles, which are essential for maintaining cell shape, motility, and migration. FSCN1 also regulates the assembly of filopodia, lamellipodia, and microspikes, which are involved in cellular movement and migration. Additionally, FSCN1 interacts with other proteins, including cytokines and growth factors, to regulate immune responses and inflammation. Its expression is upregulated in cells undergoing stress, such as during wound healing and tissue injury. **Clinical Significance:** FSCN1 has been implicated in various diseases, including cancer, cardiovascular disease, and neurological disorders. In cancer, FSCN1 is overexpressed in many types of tumors, including breast, lung, and colon cancer, suggesting a potential role in tumor progression and metastasis. In cardiovascular disease, FSCN1 has been linked to atherosclerosis and cardiac hypertrophy. In neurological disorders, FSCN1 has been implicated in amyotrophic lateral sclerosis (ALS) and Alzheimer's disease. Furthermore, FSCN1 has been identified as a potential therapeutic target for the treatment of these diseases, as its inhibition has been shown to disrupt cellular migration and invasion. **Signaling Pathways:** FSCN1 interacts with various signaling pathways, including: 1. **Cytokine signaling**: FSCN1 regulates the signaling of cytokines, such as interleukin-4 and interleukin-13, which are involved in immune responses and inflammation. 2. **Extracellular matrix signaling**: FSCN1 interacts with extracellular matrix proteins, such as collagen and laminin, to regulate cell adhesion and migration. 3. **Growth factor signaling**: FSCN1 regulates the signaling of growth factors, such as epidermal growth factor (EGF) and fibroblast growth factor (FGF), which are involved in cellular proliferation and migration. **Conclusion:** FSCN1 is a critical regulator of actin cytoskeleton dynamics and cellular migration. Its expression is significantly upregulated in cells undergoing migration, suggesting a key role in cellular movement and disease progression. As an expert immunologist, I highlight the importance of FSCN1 in understanding the mechanisms of immune responses, inflammation, and disease. Further research is necessary to fully elucidate the role of FSCN1 in various diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 503411441

Symbol: FSCN1_HUMAN

Name: Fascin

UniProtKB Accession Codes:

Q16658 A6NI89 B2RE97 Q96IC5 Q96IH1 Q9BRF1

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 6 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 13 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 36 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 19 PDBsum 19 PIR 1 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8068206

Title: cDNA cloning and expression of the human homolog of the sea urchin fascin and Drosophila singed genes which encodes an actin-bundling protein.

PubMed ID: 8068206

DOI: 10.1089/dna.1994.13.821

PubMed ID: 7933116

Title: Epstein-Barr virus infection induces expression in B lymphocytes of a novel gene encoding an evolutionarily conserved 55-kilodalton actin-bundling protein.

PubMed ID: 7933116

DOI: 10.1128/jvi.68.11.7320-7328.1994

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3525578

Title: Intracellular localization of the 55-kD actin-bundling protein in cultured cells: spatial relationships with actin, alpha-actinin, tropomyosin, and fimbrin.

PubMed ID: 3525578

DOI: 10.1083/jcb.103.2.631

PubMed ID: 8647875

Title: Phosphorylation of human fascin inhibits its actin binding and bundling activities.

PubMed ID: 8647875

DOI: 10.1074/jbc.271.21.12632

PubMed ID: 9362073

Title: Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes.

PubMed ID: 9362073

DOI: 10.1091/mbc.8.11.2345

PubMed ID: 9571235

Title: Fascin, an actin-bundling protein, induces membrane protrusions and increases cell motility of epithelial cells.

PubMed ID: 9571235

DOI: 10.1091/mbc.9.5.993

PubMed ID: 8999969

Title: Identification of an actin binding region and a protein kinase C phosphorylation site on human fascin.

PubMed ID: 8999969

DOI: 10.1074/jbc.272.4.2527

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20137952

Title: The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion.

PubMed ID: 20137952

DOI: 10.1016/j.cub.2009.12.035

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22155786

Title: Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

PubMed ID: 22155786

DOI: 10.1126/scisignal.2002060

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 21706053

Title: Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton.

PubMed ID: 21706053

DOI: 10.1038/onc.2011.256

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 20434460

Title: Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein.

PubMed ID: 20434460

DOI: 10.1016/j.jmb.2010.04.043

PubMed ID: 20393565

Title: Migrastatin analogues target fascin to block tumour metastasis.

PubMed ID: 20393565

DOI: 10.1038/nature08978

PubMed ID: 21685497

Title: Mechanism of actin filament bundling by fascin.

PubMed ID: 21685497

DOI: 10.1074/jbc.m111.251439

PubMed ID: 23184945

Title: Molecular mechanism of fascin function in filopodial formation.

PubMed ID: 23184945

DOI: 10.1074/jbc.m112.427971

Sequence Information:

  • Length: 493
  • Mass: 54530
  • Checksum: C1453714BED6109A
  • Sequence:
    • MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKQIWTLEQ PPDEAGSAAV 
CLRSHLGRYL AADKDGNVTC EREVPGPDCR FLIVAHDDGR WSLQSEAHRR YFGGTEDRLS 
CFAQTVSPAE KWSVHIAMHP QVNIYSVTRK RYAHLSARPA DEIAVDRDVP WGVDSLITLA 
FQDQRYSVQT ADHRFLRHDG RLVARPEPAT GYTLEFRSGK VAFRDCEGRY LAPSGPSGTL 
KAGKATKVGK DELFALEQSC AQVVLQAANE RNVSTRQGMD LSANQDEETD QETFQLEIDR 
DTKKCAFRTH TGKYWTLTAT GGVQSTASSK NASCYFDIEW RDRRITLRAS NGKFVTSKKN 
GQLAASVETA GDSELFLMKL INRPIIVFRG EHGFIGCRKV TGTLDANRSS YDVFQLEFND 
GAYNIKDSTG KYWTVGSDSA VTSSGDTPVD FFFEFCDYNK VAIKVGGRYL KGDHAGVLKA 
SAETVDPASL WEY

Genular Protein ID: 2651823769

Symbol: B3KTA3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KTA3

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 13 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 472
  • Mass: 52276
  • Checksum: 0316826D6A316DAC
  • Sequence:
    • MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKHLGRYLA ADKDGNVTCE 
REVPGPDCRF LIVAHDDGRW SLQSEAHRRY FGGTEDRLSC FAQTVSPAEK WSVHIAMHPQ 
VNIYSVTRKR YAHLSARPAD EIAVDRDVPW GVDSLITLAF QDQRYSVQTA DHRFLRHDGR 
LVARPEPATG YTLEFRSGKV AFRDCEGRYL APSGPSGTLK AGKATKVGKD ELFALEQSCA 
QVVLQAANER NVSTRQGMDL SANQDEETDQ ETFQLEIDRD TKKCAFRTHT GKYWTLTATG 
GVQSTASSKN ASCYFDIEWR DRRITLRASN GKFVTSKKNG QLAASVETAG DSELFLMKLI 
NRPIIVFRGE HGFIGCRKVT GTLDANRSSY DVFQLEFNDG AYNIKDSTGK YWTVGSDSAV 
TSSGDTPVDF FFEFCDYNKV AIKVGGRYLK GDHAGVLKAS AETVDPASLW EY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.