Details for: ITPRID2

Gene ID: 6744

Symbol: ITPRID2

Ensembl ID: ENSG00000138434

Description: ITPR interacting domain containing 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 322.2857
    Cell Significance Index: -50.1300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 192.7115
    Cell Significance Index: -48.8800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 111.8989
    Cell Significance Index: -52.8300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 106.0166
    Cell Significance Index: -43.0700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 94.9969
    Cell Significance Index: -48.8700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 78.8499
    Cell Significance Index: -52.9100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 45.6877
    Cell Significance Index: -43.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 41.3397
    Cell Significance Index: -50.9700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.9521
    Cell Significance Index: -50.7700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.9750
    Cell Significance Index: -51.2000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.7232
    Cell Significance Index: -21.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 4.6755
    Cell Significance Index: 544.8800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.4932
    Cell Significance Index: 113.0100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.3433
    Cell Significance Index: 122.0600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.3264
    Cell Significance Index: 31.7400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.2102
    Cell Significance Index: 103.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.7192
    Cell Significance Index: 341.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.3337
    Cell Significance Index: 267.5400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0936
    Cell Significance Index: 83.9300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.0698
    Cell Significance Index: 15.7900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.0589
    Cell Significance Index: 12.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.0460
    Cell Significance Index: 30.1400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8807
    Cell Significance Index: 19.0800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7608
    Cell Significance Index: 272.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.7200
    Cell Significance Index: 122.9500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6453
    Cell Significance Index: 285.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5332
    Cell Significance Index: 291.1900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5309
    Cell Significance Index: 65.2800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5231
    Cell Significance Index: 94.3000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.4151
    Cell Significance Index: 6.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4099
    Cell Significance Index: 23.0000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3815
    Cell Significance Index: 242.2700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3333
    Cell Significance Index: 63.4300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3112
    Cell Significance Index: 33.8500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3092
    Cell Significance Index: 213.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2178
    Cell Significance Index: 10.2400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1755
    Cell Significance Index: 330.3700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1729
    Cell Significance Index: 22.1600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1338
    Cell Significance Index: 6.9500
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.1162
    Cell Significance Index: 1.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0973
    Cell Significance Index: 6.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0952
    Cell Significance Index: 85.9200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0733
    Cell Significance Index: 10.0600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0606
    Cell Significance Index: 2.1300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0553
    Cell Significance Index: 25.0900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0182
    Cell Significance Index: 1.2900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0082
    Cell Significance Index: 12.6300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0005
    Cell Significance Index: 0.8300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0027
    Cell Significance Index: -2.0100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0280
    Cell Significance Index: -4.0700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0322
    Cell Significance Index: -43.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0416
    Cell Significance Index: -31.5200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0627
    Cell Significance Index: -46.4100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0697
    Cell Significance Index: -4.6900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0862
    Cell Significance Index: -48.6200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0905
    Cell Significance Index: -8.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1024
    Cell Significance Index: -63.9200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1046
    Cell Significance Index: -6.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1269
    Cell Significance Index: -3.4600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1365
    Cell Significance Index: -8.8100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1434
    Cell Significance Index: -16.4300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1526
    Cell Significance Index: -43.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1529
    Cell Significance Index: -15.6200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1603
    Cell Significance Index: -20.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.1972
    Cell Significance Index: -32.0700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2060
    Cell Significance Index: -10.4100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.2450
    Cell Significance Index: -1.4800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2478
    Cell Significance Index: -6.3700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2583
    Cell Significance Index: -13.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2590
    Cell Significance Index: -30.5400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2860
    Cell Significance Index: -60.2400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3117
    Cell Significance Index: -23.2300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3171
    Cell Significance Index: -3.7800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3244
    Cell Significance Index: -10.3900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3875
    Cell Significance Index: -40.3500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3988
    Cell Significance Index: -24.5100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4310
    Cell Significance Index: -12.3000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4329
    Cell Significance Index: -19.1500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4508
    Cell Significance Index: -9.6000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4659
    Cell Significance Index: -7.9900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5341
    Cell Significance Index: -42.3000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5630
    Cell Significance Index: -21.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5793
    Cell Significance Index: -16.1900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.5901
    Cell Significance Index: -9.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.6379
    Cell Significance Index: -10.6800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.6461
    Cell Significance Index: -9.1800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.6536
    Cell Significance Index: -12.0800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6874
    Cell Significance Index: -42.1400
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.7366
    Cell Significance Index: -5.2900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.7498
    Cell Significance Index: -11.0700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.8531
    Cell Significance Index: -24.4600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.8535
    Cell Significance Index: -12.1500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.8812
    Cell Significance Index: -11.3000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.9093
    Cell Significance Index: -22.7300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.9103
    Cell Significance Index: -37.3000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.0110
    Cell Significance Index: -21.6100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.0219
    Cell Significance Index: -35.5100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.0221
    Cell Significance Index: -37.5200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -1.0847
    Cell Significance Index: -6.7400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ITPRID2 is a protein that interacts with various cellular components, including actin filaments, signaling receptors, and other proteins. Its unique domain structure, comprising an ITPRID domain, allows it to bind to actin filaments and regulate their dynamics. This interaction is crucial for maintaining cellular structure and function, particularly in cells involved in muscle contraction, such as cardiac muscle cells. Additionally, ITPRID2's ability to interact with signaling receptors and other proteins suggests its involvement in signaling pathways that regulate cellular responses to external stimuli. **Pathways and Functions** ITPRID2 is implicated in several cellular pathways, including: 1. **Actin filament binding**: ITPRID2's interaction with actin filaments regulates their dynamics, which is essential for maintaining cellular structure and function, particularly in muscle cells. 2. **Signaling receptor binding**: ITPRID2 interacts with various signaling receptors, including those involved in immune responses, such as CD14 and CD16. 3. **Protein binding**: ITPRID2's ITPRID domain allows it to bind to other proteins, including those involved in cellular signaling and regulation. 4. **Cytoskeleton organization**: ITPRID2's interaction with actin filaments and other proteins regulates cytoskeleton organization, which is critical for maintaining cellular shape and function. **Clinical Significance** While ITPRID2's role in cellular processes is well-established, its clinical significance is still evolving. However, its expression in specific cell types, such as cardiac muscle cells and endothelial cells, suggests its potential involvement in cardiovascular and vascular diseases. Additionally, ITPRID2's interaction with immune cells, such as CD14-low, CD16-positive monocytes, may have implications for immune-related disorders. Furthermore, ITPRID2's expression in certain cancer cell types, such as extravillous trophoblasts, suggests its potential involvement in cancer progression and metastasis. Further research is needed to fully elucidate ITPRID2's clinical significance and its role in various diseases. In conclusion, ITPRID2 is a protein with a complex role in various cellular processes, including actin filament binding, signaling, and protein interactions. Its expression in specific cell types and its involvement in various cellular pathways suggest its potential significance in cardiovascular, immune, and cancer-related disorders. Further research is necessary to fully understand ITPRID2's clinical significance and its role in human disease.

Genular Protein ID: 4090490051

Symbol: ITPI2_HUMAN

Name: Sperm-specific antigen 2

UniProtKB Accession Codes:

P28290 A8K6T0 Q68DA6 Q7Z7L2 Q8N1L3 Q8N263 Q8N7H2 Q8NEN5 Q96E36 Q96PW1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 2 ExpressionAtlas 1 GO 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 4 SMART 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14673706

Title: Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells.

PubMed ID: 14673706

DOI: 10.1007/s10038-003-0106-3

PubMed ID: 11572484

Title: Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

PubMed ID: 11572484

DOI: 10.1093/dnares/8.4.179

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1555770

Title: Human cleavage signal-1 protein; cDNA cloning, transcription and immunological analysis.

PubMed ID: 1555770

DOI: 10.1016/0378-1119(92)90377-2

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 1259
  • Mass: 138386
  • Checksum: D5843D9D6D5414D7
  • Sequence:
    • MDRPLSSSAE AEEELEWQVA SRRRKAWAKC RSSWQASETE DLSTEATTQD EEEDEEEDLP 
GAQLPAAGGR GNVPNEKIAI WLKDCRTPLG ASLDEQSSST LKGVLVRNGG SFEDDLSLGA 
EANHLHESDA QIENCNNILA KERRLQFHQK GRSMNSTGSG KSSGTVSSVS ELLELYEEDP 
EEILYNLGFG RDEPDIASKI PSRFFNSSSF AKGIDIKVFL SAQMQRMEVE NPNYALTSRF 
RQIEVLTTVA NAFSSLYSQV SGTPLQRIGS MSSVTSNKET DPPPPLTRSN TANRLMKTLS 
KLNLCVDKTE KGESSSPSPS AEKGKILNVS VIEESGNKND QKSQKIMKKK ESSSMLATVK 
EEVSGSSAAV TENADSDRIS DEANSNFNQG TENEQSKETQ SHESKLGEES GIVESKLDSD 
FNISSHSELE NSSELKSVHI STPEKEPCAP LTIPSIRNIM TQQKDSFEME EVQSTEGEAP 
HVPATYQLGL TKSKRDHLLR TASQHSDSSG FAEDSTDCLS LNHLQVQESL QAMGSSADSC 
DSETTVTSLG EDLATPTAQD QPYFNESEEE SLVPLQKGLE KAAAVADKRK SGSQDFPQCN 
TIENTGTKQS TCSPGDHIIE ITEVEEDLFP AETVELLREA SAESDVGKSS ESEFTQYTTH 
HILKSLASIE AKCSDMSSEN TTGPPSSMDR VNTALQRAQM KVCSLSNQRM GRSLLKSKDL 
LKQRYLFAKA GYPLRRSQSL PTTLLSPVRV VSSVNVRLSP GKETRCSPPS FTYKYTPEEE 
QELEKRVMEH DGQSLVKSTI FISPSSVKKE EAPQSEAPRV EECHHGRTPT CSRLAPPPMS 
QSTCSLHSIH SEWQERPLCE HTRTLSTHSV PNISGATCSA FASPFGCPYS HRHATYPYRV 
CSVNPPSAIE MQLRRVLHDI RNSLQNLSQY PMMRGPDPAA APYSTQKSSV LPLYENTFQE 
LQVMRRSLNL FRTQMMDLEL AMLRQQTMVY HHMTEEERFE VDQLQGLRNS VRMELQDLEL 
QLEERLLGLE EQLRAVRMPS PFRSSALMGM CGSRSADNLS CPSPLNVMEP VTELMQEQSY 
LKSELGLGLG EMGFEIPPGE SSESVFSQAT SESSSVCSGP SHANRRTGVP STASVGKSKT 
PLVARKKVFR ASVALTPTAP SRTGSVQTPP DLESSEEVDA AEGAPEVVGP KSEVEEGHGK 
LPSMPAAEEM HKNVEQDELQ QVIREIKESI VGEIRREIVS GLLAAVSSSK ASNSKQDYH

Genular Protein ID: 1357592374

Symbol: E9PHV5_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PHV5

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 GeneTree 1 HGNC 1 IntAct 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 1237
  • Mass: 136138
  • Checksum: 64BFA619E2C53DDA
  • Sequence:
    • MDRPLSSSAE AEEELEWQVA SRRRKAWAKC RSSWQASETE DLSTEATTQD EEEDEEEDLP 
GAQLPAAGGR GNVPNEKIAI WLKDCRTPLG ASLDEQSSST LKGVLVRNGG SFEDDLSLGA 
EANHLHESDA QIENCNNILA KERRLQFHQK GRSMNSTGSG KSSGTVSSVS ELLELYEEDP 
EEILYNLGFG RDEPDIASKI PSRFFNSSSF AKGIDIKVFL SAQMQRMEVE NPNYALTSRF 
RQIEVLTTVA NAFSSLYSQV SGTPLQRIGS MSSVTSNKET DPPPPLTRSN TANRLMKTLS 
KLNLCVDKTE KGESSSPSPS AEKGKILNVS VIEESGNKND QKSQKIMKKK ESSSMLATVK 
EEVSGSSAAV TENADSDRIS DEANSNFNQG TENEQSKETQ SHESKLGEES GIVESKLDSD 
FNISSHSELE NSSELKSVHI STPEKEPCAP LTIPSIRNIM TQQKDSFEME EVQSTEGEAP 
HVPATYQLGL TKSKRDHLLR TASQHSDSSG FAEDSTDCLS LNHLQVQESL QAMGSSADSC 
DSETTVTSLG EDLATPTAQD QPYFNESEEE SLVPLQKGLE KAAAVADKRK SGSQDFPQCN 
TIENTGTKQS TCSPGDHIIE ITEVEEDLFP AETVELLREA SAESDVGKSS ESEFTQYTTH 
HILKSLASIE AKCSDMSSEN TTGPPSSMDR VNTALQRAQM KVCSLSNQRM GRSLLKSKDL 
LKQRYLFAKA GYPLRRSQSL PTTLLSPVRV VSSVNVRLSP GKETRCSPPS FTYKYTPEEE 
QELEKRVMEH DGQSLVKSTI FISPSSVKKE EAPQSEAPRV EECHHGRTPT CSRLAPPPMS 
QSTCSLHSIH SEWQERPLCE HTRTLSTHSV PNISGATCSA FASPFGCPYS HRHATYPYRV 
CSVNPPSAIE MQLRRVLHDI RNSLQNLSQY PMMRGPDPAA APYSTQKSSV LPLYENTFQE 
LQVMRRSLNL FRTQMMDLEL AMLRQQTMVY HHMTEEERFE VDQLQGLRNS VRMELQDLEL 
QLEERLLGLE EQLRAVRMPS PFRSSALMVT ELMQEQSYLK SELGLGLGEM GFEIPPGESS 
ESVFSQATSE SSSVCSGPSH ANRRTGVPST ASVGKSKTPL VARKKVFRAS VALTPTAPSR 
TGSVQTPPDL ESSEEVDAAE GAPEVVGPKS EVEEGHGKLP SMPAAEEMHK NVEQDELQQV 
IREIKESIVG EIRREIVSGL LAAVSSSKAS NSKQDYH

Genular Protein ID: 4274525900

Symbol: E7EUL7_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EUL7

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 3 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 768
  • Mass: 84593
  • Checksum: C2DC1907B353BF31
  • Sequence:
    • MTTEDHLLRT ASQHSDSSGF AEDSTDCLSL NHLQVQESLQ AMGSSADSCD SETTVTSLGE 
DLATPTAQDQ PYFNESEEES LVPLQKGLEK AAAVADKRKS GSQDFPQCNT IENTGTKQST 
CSPGDHIIEI TEVEEDLFPA ETVELLREAS AESDVGKSSE SEFTQYTTHH ILKSLASIEA 
KCSDMSSENT TGPPSSMDRV NTALQRAQMK VCSLSNQRMG RSLLKSKDLL KQRYLFAKAG 
YPLRRSQSLP TTLLSPVRVV SSVNVRLSPG KETRCSPPSF TYKYTPEEEQ ELEKRVMEHD 
GQSLVKSTIF ISPSSVKKEE APQSEAPRVE ECHHGRTPTC SRLAPPPMSQ STCSLHSIHS 
EWQERPLCEH TRTLSTHSVP NISGATCSAF ASPFGCPYSH RHATYPYRVC SVNPPSAIEM 
QLRRVLHDIR NSLQNLSQYP MMRGPDPAAA PYSTQKSSVL PLYENTFQEL QVMRRSLNLF 
RTQMMDLELA MLRQQTMVYH HMTEEERFEV DQLQGLRNSV RMELQDLELQ LEERLLGLEE 
QLRAVRMPSP FRSSALMGMC GSRSADNLSC PSPLNVMEPV TELMQEQSYL KSELGLGLGE 
MGFEIPPGES SESVFSQATS ESSSVCSGPS HANRRTGVPS TASVGKSKTP LVARKKVFRA 
SVALTPTAPS RTGSVQTPPD LESSEEVDAA EGAPEVVGPK SEVEEGHGKL PSMPAAEEMH 
KNVEQDELQQ VIREIKESIV GEIRREIVSG LLAAVSSSKA SNSKQDYH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.