Details for: SSR1

Gene ID: 6745

Symbol: SSR1

Ensembl ID: ENSG00000124783

Description: signal sequence receptor subunit 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 340.5762
    Cell Significance Index: -52.9800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 189.1632
    Cell Significance Index: -47.9800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 135.9604
    Cell Significance Index: -64.1900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 132.1085
    Cell Significance Index: -53.6700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 119.3755
    Cell Significance Index: -61.4100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 95.6600
    Cell Significance Index: -64.1900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 56.3398
    Cell Significance Index: -53.7900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 47.0374
    Cell Significance Index: -58.0000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.3739
    Cell Significance Index: -51.9000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 15.6929
    Cell Significance Index: -48.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.9339
    Cell Significance Index: -58.9300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.3394
    Cell Significance Index: -20.4400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.9196
    Cell Significance Index: 89.5000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.4294
    Cell Significance Index: 196.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2408
    Cell Significance Index: 248.9000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.2069
    Cell Significance Index: 659.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1960
    Cell Significance Index: 237.3500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.9335
    Cell Significance Index: 24.9300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8922
    Cell Significance Index: 320.0200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8669
    Cell Significance Index: 156.2700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.8622
    Cell Significance Index: 106.0200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.8386
    Cell Significance Index: 15.5000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8288
    Cell Significance Index: 22.5600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7718
    Cell Significance Index: 98.9500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.7327
    Cell Significance Index: 323.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6870
    Cell Significance Index: 51.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6696
    Cell Significance Index: 31.4700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6232
    Cell Significance Index: 431.0300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5808
    Cell Significance Index: 63.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5003
    Cell Significance Index: 31.5300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4170
    Cell Significance Index: 26.9000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3826
    Cell Significance Index: 72.8200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3721
    Cell Significance Index: 36.8100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.3619
    Cell Significance Index: 19.0000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3517
    Cell Significance Index: 41.4800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3439
    Cell Significance Index: 10.1000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.3354
    Cell Significance Index: 3.8100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.3253
    Cell Significance Index: 6.8100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3132
    Cell Significance Index: 22.1500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2954
    Cell Significance Index: 38.1600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.2684
    Cell Significance Index: 3.2000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2412
    Cell Significance Index: 217.7600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2164
    Cell Significance Index: 36.9600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1722
    Cell Significance Index: 4.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1706
    Cell Significance Index: 4.4900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.1361
    Cell Significance Index: 3.1500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0905
    Cell Significance Index: 68.5000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0659
    Cell Significance Index: 1.7600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0270
    Cell Significance Index: 1.4000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0255
    Cell Significance Index: 1.1300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0106
    Cell Significance Index: 20.0200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0036
    Cell Significance Index: 0.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0027
    Cell Significance Index: 1.9900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0016
    Cell Significance Index: -0.0900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0022
    Cell Significance Index: -0.1300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0140
    Cell Significance Index: -0.3900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0263
    Cell Significance Index: -35.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0285
    Cell Significance Index: -52.5800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0301
    Cell Significance Index: -46.3800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0328
    Cell Significance Index: -20.8400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0351
    Cell Significance Index: -1.3300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0493
    Cell Significance Index: -0.8200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0525
    Cell Significance Index: -5.3600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0575
    Cell Significance Index: -42.6300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0705
    Cell Significance Index: -11.4700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0748
    Cell Significance Index: -33.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0926
    Cell Significance Index: -52.2500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1144
    Cell Significance Index: -71.4600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1787
    Cell Significance Index: -51.4200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1802
    Cell Significance Index: -5.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1805
    Cell Significance Index: -21.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1847
    Cell Significance Index: -14.1800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2043
    Cell Significance Index: -4.3500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2389
    Cell Significance Index: -10.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.2467
    Cell Significance Index: -8.6700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.2743
    Cell Significance Index: -18.9700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2876
    Cell Significance Index: -41.8100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2972
    Cell Significance Index: -18.2700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3115
    Cell Significance Index: -65.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3185
    Cell Significance Index: -36.5000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3621
    Cell Significance Index: -9.2500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3641
    Cell Significance Index: -6.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5109
    Cell Significance Index: -17.7600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5240
    Cell Significance Index: -15.0200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5354
    Cell Significance Index: -11.6000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5440
    Cell Significance Index: -56.6400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6383
    Cell Significance Index: -17.0800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6831
    Cell Significance Index: -35.5800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7008
    Cell Significance Index: -55.5000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.8036
    Cell Significance Index: -7.4000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -1.0176
    Cell Significance Index: -19.8600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.0328
    Cell Significance Index: -63.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.0580
    Cell Significance Index: -26.4500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.0606
    Cell Significance Index: -14.4700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.1641
    Cell Significance Index: -33.2200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.2095
    Cell Significance Index: -35.6300
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -1.2392
    Cell Significance Index: -7.7000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.2499
    Cell Significance Index: -63.1700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.2603
    Cell Significance Index: -26.9400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.2783
    Cell Significance Index: -27.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SSR1 is a gene that encodes a protein subunit of the translocon complex, which is responsible for the cotranslational targeting of proteins to the ER membrane. The protein consists of two subunits, alpha and beta, with SSR1 specifically associated with the alpha subunit. SSR1 has a high degree of sequence similarity to other translocon-associated proteins, suggesting a conserved functional role across species. **Pathways and Functions** SSR1 is involved in several cellular pathways, including: 1. **Cotranslational protein targeting to membrane**: SSR1 plays a crucial role in the targeting of proteins to the ER membrane through its association with the translocon complex. 2. **Endoplasmic reticulum (ER) stress response**: SSR1 is part of the unfolded protein response (UPR), a cellular response to ER stress, which involves the activation of chaperones and the regulation of protein folding. 3. **Metabolism of proteins**: SSR1 is involved in the proper folding and targeting of proteins to the ER membrane, which is essential for protein function and cellular homeostasis. 4. **Positive regulation of cell population proliferation**: SSR1 has been shown to promote cell proliferation by regulating the expression of genes involved in cell cycle progression. **Clinical Significance** Dysregulation of SSR1 has been implicated in various diseases, including: 1. **Pancreatic disorders**: Mutations in SSR1 have been associated with pancreatic disorders, such as pancreatitis and pancreatic cancer. 2. **Autoimmune diseases**: SSR1 has been implicated in autoimmune diseases, such as rheumatoid arthritis and lupus, where it is thought to play a role in the regulation of immune cell function. 3. **Cancer**: SSR1 has been shown to be overexpressed in certain types of cancer, including breast and lung cancer, where it may contribute to tumorigenesis. In conclusion, SSR1 is a critical gene involved in the regulation of protein targeting to the ER membrane and the UPR. Its dysregulation has been implicated in various diseases, highlighting the importance of SSR1 in maintaining cellular homeostasis and preventing disease. Further research is needed to fully elucidate the functional role of SSR1 and its potential as a therapeutic target.

Genular Protein ID: 656430559

Symbol: SSRA_HUMAN

Name: Translocon-associated protein subunit alpha

UniProtKB Accession Codes:

P43307 A8K685 Q53GX2 Q53H19 Q5TAM3 Q6IB43 Q8NBH9 Q96IA2 Q9TNQ8 Q9UN49

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 2 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 EMDB 1 Ensembl 1 ExpressionAtlas 1 GO 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 SMR 1 STRING 1 SignaLink 1 TCDB 1 TopDownProteomics 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8050590

Title: The N-terminal region of the alpha-subunit of the TRAP complex has a conserved cluster of negative charges.

PubMed ID: 8050590

DOI: 10.1016/0014-5793(94)00693-8

PubMed ID: 10437777

Title: Translocon-associated protein alpha transcripts are induced by granulocyte-macrophage colony-stimulating factor and exhibit complex alternative polyadenylation.

PubMed ID: 10437777

DOI: 10.1016/s0014-5793(99)00885-6

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1557127

Title: HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides.

PubMed ID: 1557127

DOI: 10.1038/356443a0

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22314232

Title: Palmitoylated calnexin is a key component of the ribosome-translocon complex.

PubMed ID: 22314232

DOI: 10.1038/emboj.2012.15

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 286
  • Mass: 32235
  • Checksum: 2C631DC0CC3EB489
  • Sequence:
    • MRLLPRLLLL LLLVFPATVL FRGGPRGLLA VAQDLTEDEE TVEDSIIEDE DDEAEVEEDE 
PTDLVEDKEE EDVSGEPEAS PSADTTILFV KGEDFPANNI VKFLVGFTNK GTEDFIVESL 
DASFRYPQDY QFYIQNFTAL PLNTVVPPQR QATFEYSFIP AEPMGGRPFG LVINLNYKDL 
NGNVFQDAVF NQTVTVIERE DGLDGETIFM YMFLAGLGLL VIVGLHQLLE SRKRKRPIQK 
VEMGTSSQND VDMSWIPQET LNQINKASPR RLPRKRAQKR SVGSDE

Genular Protein ID: 3749436984

Symbol: C9JBX5_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9JBX5

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 GeneTree 1 HGNC 1 InterPro 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 2 SMR 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 218
  • Mass: 24411
  • Checksum: 00DCD67AF9546ACB
  • Sequence:
    • MRLLPRLLLL LLLVFPATVL FRGGPRGLLA VAQDLTEDEE TVEDSIIEDE DDEAEVEEDE 
PTDLVEDKEE EDVSGEPEAS PSADTTILFV KGEEPMGGRP FGLVINLNYK DLNGNVFQDA 
VFNQTVTVIE REDGLDGETI FMYMFLAGLG LLVIVGLHQL LESRKRKRPI QKVEMGTSSQ 
NDVDMSWIPQ ETLNQINKAS PRRLPRKRAQ KRSVGSDE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.