Details for: PRDX2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 343.1590
Cell Significance Index: -87.0400 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 269.5003
Cell Significance Index: -111.0200 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 232.3337
Cell Significance Index: -109.6900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 207.3835
Cell Significance Index: -106.6800 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 164.0780
Cell Significance Index: -110.1000 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 86.2772
Cell Significance Index: -13.4200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 57.4798
Cell Significance Index: -70.8700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 28.0787
Cell Significance Index: -110.8000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 27.1123
Cell Significance Index: -72.6300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 25.6849
Cell Significance Index: -78.8900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 8.0562
Cell Significance Index: 422.9800 - Cell Name: kidney cell (CL1000497)
Fold Change: 7.3908
Cell Significance Index: 59.0100 - Cell Name: granulosa cell (CL0000501)
Fold Change: 6.9527
Cell Significance Index: 182.8200 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 6.0068
Cell Significance Index: 46.3000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 5.9822
Cell Significance Index: 207.8800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 5.7323
Cell Significance Index: 48.1500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 4.8453
Cell Significance Index: 101.4200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 4.7134
Cell Significance Index: 219.7600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 4.6085
Cell Significance Index: 50.1000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 4.2887
Cell Significance Index: 1233.9800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 3.9239
Cell Significance Index: 57.9300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 3.8753
Cell Significance Index: 2116.3800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 3.8277
Cell Significance Index: 525.6500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.8257
Cell Significance Index: 49.0000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 3.3945
Cell Significance Index: 417.3800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 3.2321
Cell Significance Index: 582.6500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 3.1305
Cell Significance Index: 91.9400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 2.8086
Cell Significance Index: 209.3200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 2.6077
Cell Significance Index: 184.4300 - Cell Name: peg cell (CL4033014)
Fold Change: 2.4105
Cell Significance Index: 55.6900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 2.4025
Cell Significance Index: 1062.1900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 2.3709
Cell Significance Index: 26.9400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.0725
Cell Significance Index: 337.0700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 1.9097
Cell Significance Index: 89.7600 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.7414
Cell Significance Index: 223.2400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.7049
Cell Significance Index: 15.7000 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.7037
Cell Significance Index: 220.1100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.5307
Cell Significance Index: 41.0200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.4196
Cell Significance Index: 89.4700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.3735
Cell Significance Index: 71.3500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.2829
Cell Significance Index: 34.9200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.1036
Cell Significance Index: 23.9100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8566
Cell Significance Index: 171.8400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.8552
Cell Significance Index: 100.8500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.8097
Cell Significance Index: 56.0000 - Cell Name: theca cell (CL0000503)
Fold Change: 0.7864
Cell Significance Index: 4.6200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.6581
Cell Significance Index: 112.3700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.6105
Cell Significance Index: 447.6100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4748
Cell Significance Index: 170.2900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.4009
Cell Significance Index: 31.7600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2439
Cell Significance Index: 46.4200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.1999
Cell Significance Index: 151.3100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1970
Cell Significance Index: 8.9300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.1721
Cell Significance Index: 2.8800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1315
Cell Significance Index: 4.6200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0657
Cell Significance Index: 4.2400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0648
Cell Significance Index: 3.8900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0369
Cell Significance Index: 2.2700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0208
Cell Significance Index: 2.0600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0205
Cell Significance Index: 14.2100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0310
Cell Significance Index: -22.9800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0469
Cell Significance Index: -2.3700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0522
Cell Significance Index: -98.2000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0709
Cell Significance Index: -130.7900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0849
Cell Significance Index: -130.7200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0971
Cell Significance Index: -132.0900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1186
Cell Significance Index: -74.0600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1377
Cell Significance Index: -77.6700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.1455
Cell Significance Index: -92.3800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1616
Cell Significance Index: -16.5100 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1937
Cell Significance Index: -7.9400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2086
Cell Significance Index: -5.5700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2138
Cell Significance Index: -24.5000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.2295
Cell Significance Index: -104.1700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2328
Cell Significance Index: -49.0400 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: -0.2640
Cell Significance Index: -2.8100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5734
Cell Significance Index: -66.8200 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.6165
Cell Significance Index: -15.7500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.6330
Cell Significance Index: -35.5200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.7153
Cell Significance Index: -103.9800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.7849
Cell Significance Index: -25.1400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.8168
Cell Significance Index: -62.6800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -1.0156
Cell Significance Index: -115.9300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -1.0727
Cell Significance Index: -111.6900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -1.1567
Cell Significance Index: -30.9400 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -1.1588
Cell Significance Index: -7.2000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -1.2402
Cell Significance Index: -35.5500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -1.4521
Cell Significance Index: -25.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.6484
Cell Significance Index: -101.0600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.7433
Cell Significance Index: -90.8100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -1.7591
Cell Significance Index: -24.0000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -1.7929
Cell Significance Index: -52.8100 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: -1.8311
Cell Significance Index: -16.1300 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -1.8319
Cell Significance Index: -17.4300 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: -1.9828
Cell Significance Index: -22.4000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -2.0637
Cell Significance Index: -24.6000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -2.1544
Cell Significance Index: -36.9200 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -2.1984
Cell Significance Index: -45.8500 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -2.2115
Cell Significance Index: -13.6100 - Cell Name: sensory neuron (CL0000101)
Fold Change: -2.2853
Cell Significance Index: -12.9900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3342656669
Symbol: PRDX2_HUMAN
Name: Peroxiredoxin-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8144038
Title: The thiol-specific antioxidant protein from human brain: gene cloning and analysis of conserved cysteine regions.
PubMed ID: 8144038
PubMed ID: 8026862
Title: Cloning and sequence analysis of candidate human natural killer-enhancing factor genes.
PubMed ID: 8026862
DOI: 10.1007/bf00188176
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8554614
Title: Thioredoxin-linked peroxidase from human red blood cell: evidence for the existence of thioredoxin and thioredoxin reductase in human red blood cell.
PubMed ID: 8554614
PubMed ID: 8313871
Title: Plasma and red blood cell protein maps: update 1993.
PubMed ID: 8313871
PubMed ID: 9150948
Title: A two-dimensional gel database of human colon carcinoma proteins.
PubMed ID: 9150948
PubMed ID: 1286667
Title: Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.
PubMed ID: 1286667
PubMed ID: 9497357
Title: Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha.
PubMed ID: 9497357
PubMed ID: 11904290
Title: Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site.
PubMed ID: 11904290
PubMed ID: 12853451
Title: Regeneration of peroxiredoxins during recovery after oxidative stress: only some overoxidized peroxiredoxins can be reduced during recovery after oxidative stress.
PubMed ID: 12853451
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 17141802
Title: Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.
PubMed ID: 17141802
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 10873855
Title: Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7 A resolution.
PubMed ID: 10873855
PubMed ID: 27892488
Title: Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins.
PubMed ID: 27892488
DOI: 10.1038/srep37610
Sequence Information:
- Length: 198
- Mass: 21892
- Checksum: 1AC781D908B32B46
- Sequence:
MASGNARIGK PAPDFKATAV VDGAFKEVKL SDYKGKYVVL FFYPLDFTFV CPTEIIAFSN RAEDFRKLGC EVLGVSVDSQ FTHLAWINTP RKEGGLGPLN IPLLADVTRR LSEDYGVLKT DEGIAYRGLF IIDGKGVLRQ ITVNDLPVGR SVDEALRLVQ AFQYTDEHGE VCPAGWKPGS DTIKPNVDDS KEYFSKHN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.