Gene TFDP2 - ENSG00000114126 | NCBI Gene ID: 7029

Details for: TFDP2

Gene ID: 7029

Symbol: TFDP2

Ensembl ID: ENSG00000114126

Description: transcription factor Dp-2

Associated with

Aberrant regulation of mitotic cell cycle due to rb1 defects
(R-HSA-9687139)
Aberrant regulation of mitotic g1/s transition in cancer due to rb1 defects
(R-HSA-9659787)
Activation of bh3-only proteins
(R-HSA-114452)
Activation of noxa and translocation to mitochondria
(R-HSA-111448)
Activation of puma and translocation to mitochondria
(R-HSA-139915)
Apoptosis
(R-HSA-109581)
Cell cycle, mitotic
(R-HSA-69278)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular senescence
(R-HSA-2559583)
Cyclin a:cdk2-associated events at s phase entry
(R-HSA-69656)
Cyclin d associated events in g1
(R-HSA-69231)
Cyclin e associated events during g1/s transition
(R-HSA-69202)
Defective binding of rb1 mutants to e2f1,(e2f2, e2f3)
(R-HSA-9661069)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of mitotic cell cycle
(R-HSA-9675126)
E2f mediated regulation of dna replication
(R-HSA-113510)
G0 and early g1
(R-HSA-1538133)
G1 phase
(R-HSA-69236)
G1/s-specific transcription
(R-HSA-69205)
G1/s transition
(R-HSA-69206)
Gene expression (transcription)
(R-HSA-74160)
Generic transcription pathway
(R-HSA-212436)
Inhibition of replication initiation of damaged dna by rb1/e2f1
(R-HSA-113501)
Intrinsic pathway for apoptosis
(R-HSA-109606)
Mitotic g1 phase and g1/s transition
(R-HSA-453279)
Oncogene induced senescence
(R-HSA-2559585)
Oxidative stress induced senescence
(R-HSA-2559580)
Pre-notch expression and processing
(R-HSA-1912422)
Pre-notch transcription and translation
(R-HSA-1912408)
Programmed cell death
(R-HSA-5357801)
Rna polymerase ii transcription
(R-HSA-73857)
Signaling by notch
(R-HSA-157118)
Signaling by tgf-beta receptor complex
(R-HSA-170834)
Signaling by tgfb family members
(R-HSA-9006936)
Signal transduction
(R-HSA-162582)
Smad2/smad3:smad4 heterotrimer regulates transcription
(R-HSA-2173796)
S phase
(R-HSA-69242)
Tp53 regulates transcription of cell cycle genes
(R-HSA-6791312)
Tp53 regulates transcription of genes involved in g2 cell cycle arrest
(R-HSA-6804114)
Transcriptional activity of smad2/smad3:smad4 heterotrimer
(R-HSA-2173793)
Transcriptional regulation by e2f6
(R-HSA-8953750)
Transcriptional regulation by tp53
(R-HSA-3700989)
Transcriptional regulation of granulopoiesis
(R-HSA-9616222)
Transcription of e2f targets under negative control by dream complex
(R-HSA-1362277)
Transcription of e2f targets under negative control by p107 (rbl1) and p130 (rbl2) in complex with hdac1
(R-HSA-1362300)
Cell cycle
(GO:0007049)
Chromatin
(GO:0000785)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Heart development
(GO:0007507)
Mitotic spindle
(GO:0072686)
Negative regulation of dna-templated transcription
(GO:0045892)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Regulation of cell cycle
(GO:0051726)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Transcription factor binding
(GO:0008134)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: GABAergic neuron (CL0000617)
Fold Change: 3.88
Marker Score: 16181
Cell Name: thymocyte (CL0000893)
Fold Change: 2.92
Marker Score: 3055
Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 2.77
Marker Score: 2278
Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 2.7
Marker Score: 2390.5
Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.59
Marker Score: 1800
Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.55
Marker Score: 11798
Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.52
Marker Score: 95784
Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 2.5
Marker Score: 1404
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.47
Marker Score: 10356.5
Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.42
Marker Score: 2924
Cell Name: photoreceptor cell (CL0000210)
Fold Change: 2.4
Marker Score: 1804
Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.39
Marker Score: 47635
Cell Name: taste receptor cell (CL0000209)
Fold Change: 2.39
Marker Score: 2062
Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.36
Marker Score: 18052.5
Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.35
Marker Score: 35167.5
Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.29
Marker Score: 84548
Cell Name: neuronal brush cell (CL0000555)
Fold Change: 2.27
Marker Score: 7597
Cell Name: anterior lens cell (CL0002223)
Fold Change: 2.26
Marker Score: 3040
Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.26
Marker Score: 9368
Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.25
Marker Score: 50355.5
Cell Name: pro-T cell (CL0000827)
Fold Change: 2.22
Marker Score: 9085
Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 2.22
Marker Score: 704
Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 2.21
Marker Score: 924
Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 2.13
Marker Score: 11183
Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.13
Marker Score: 8224
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.12
Marker Score: 37711
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 2.11
Marker Score: 8283
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.07
Marker Score: 606
Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.07
Marker Score: 2577.5
Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.07
Marker Score: 3473
Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.05
Marker Score: 43688
Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 2.04
Marker Score: 1283
Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.01
Marker Score: 18896
Cell Name: renal principal cell (CL0005009)
Fold Change: 2
Marker Score: 1538
Cell Name: fat cell (CL0000136)
Fold Change: 1.99
Marker Score: 1114
Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.98
Marker Score: 3814
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.97
Marker Score: 121176
Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.96
Marker Score: 8189
Cell Name: stellate neuron (CL0000122)
Fold Change: 1.94
Marker Score: 10394.5
Cell Name: neural crest cell (CL0011012)
Fold Change: 1.93
Marker Score: 2065
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.91
Marker Score: 19696
Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 1.9
Marker Score: 1250
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.9
Marker Score: 2150
Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1.9
Marker Score: 1783
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.88
Marker Score: 4137
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.87
Marker Score: 592
Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 1.86
Marker Score: 5051
Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.84
Marker Score: 17477.5
Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.82
Marker Score: 875
Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.82
Marker Score: 1963
Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 1.8
Marker Score: 2160.5
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.8
Marker Score: 15443.5
Cell Name: lymphocyte (CL0000542)
Fold Change: 1.76
Marker Score: 889
Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.75
Marker Score: 4990
Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1.73
Marker Score: 1758
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 1.72
Marker Score: 1904
Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.72
Marker Score: 3588
Cell Name: neuron (CL0000540)
Fold Change: 1.71
Marker Score: 6974
Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.7
Marker Score: 992
Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 1.7
Marker Score: 465
Cell Name: macroglial cell (CL0000126)
Fold Change: 1.7
Marker Score: 3899
Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.67
Marker Score: 978
Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
Fold Change: 1.66
Marker Score: 2353
Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.65
Marker Score: 421
Cell Name: granulosa cell (CL0000501)
Fold Change: 1.65
Marker Score: 16614.5
Cell Name: male germ cell (CL0000015)
Fold Change: 1.64
Marker Score: 472
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.63
Marker Score: 1742.5
Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
Fold Change: 1.63
Marker Score: 1178
Cell Name: Unknown (CL0002371)
Fold Change: 1.62
Marker Score: 1723
Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.62
Marker Score: 1865
Cell Name: oligodendrocyte (CL0000128)
Fold Change: 1.61
Marker Score: 3866
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.61
Marker Score: 4021
Cell Name: erythroid progenitor cell, mammalian (CL0001066)
Fold Change: 1.61
Marker Score: 515
Cell Name: kidney cell (CL1000497)
Fold Change: 1.6
Marker Score: 1070.5
Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.6
Marker Score: 54085.5
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.58
Marker Score: 2433
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 1.57
Marker Score: 1656
Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.57
Marker Score: 4195
Cell Name: granule cell (CL0000120)
Fold Change: 1.56
Marker Score: 11794.5
Cell Name: skin fibroblast (CL0002620)
Fold Change: 1.56
Marker Score: 404
Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.55
Marker Score: 5520
Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.55
Marker Score: 11541
Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.55
Marker Score: 2190
Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.55
Marker Score: 5729
Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.53
Marker Score: 1458
Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 1.51
Marker Score: 1521
Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
Fold Change: 1.51
Marker Score: 650
Cell Name: hepatoblast (CL0005026)
Fold Change: 1.5
Marker Score: 4927
Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.49
Marker Score: 349
Cell Name: hematopoietic precursor cell (CL0008001)
Fold Change: 1.49
Marker Score: 520
Cell Name: glial cell (CL0000125)
Fold Change: 1.48
Marker Score: 1631
Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.48
Marker Score: 720
Cell Name: mesenchymal cell (CL0008019)
Fold Change: 1.48
Marker Score: 2520
Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.48
Marker Score: 824
Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 1.47
Marker Score: 773
Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.45
Marker Score: 1535
Cell Name: mural cell (CL0008034)
Fold Change: 1.45
Marker Score: 165885
Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.44
Marker Score: 9343
Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.43
Marker Score: 3887
Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.43
Marker Score: 1766

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**Key Characteristics** TFDP2 is a transcription factor that belongs to the E2F family, which is characterized by its ability to bind to specific DNA sequences and regulate the expression of target genes involved in cell cycle progression, apoptosis, and cellular responses to stress. TFDP2's expression is tightly regulated by the retinoblastoma protein (Rb) and the p53 tumor suppressor, which are key regulators of the cell cycle and apoptosis. TFDP2's involvement in the regulation of cell cycle and apoptosis has significant implications for our understanding of immune cell development, homeostasis, and the pathogenesis of immune-related disorders. **Pathways and Functions** TFDP2 plays a crucial role in regulating cell cycle progression, apoptosis, and cellular responses to stress. Its involvement in the regulation of cell cycle progression is mediated through its binding to specific DNA sequences, which activate the expression of target genes involved in cell cycle progression. TFDP2's role in apoptosis is mediated through its activation of pro-apoptotic proteins, such as Noxa and Puma, which are involved in the regulation of mitochondrial function and the induction of apoptosis. TFDP2's involvement in cellular responses to stress is mediated through its activation of stress response pathways, such as the unfolded protein response (UPR) and the endoplasmic reticulum stress response (ER stress response). **Clinical Significance** TFDP2's involvement in the regulation of cell cycle progression, apoptosis, and cellular responses to stress has significant implications for our understanding of immune cell development, homeostasis, and the pathogenesis of immune-related disorders. Dysregulation of TFDP2's expression and activity has been implicated in various immune-related disorders, including cancer, autoimmune diseases, and immunodeficiency diseases. For example, TFDP2's dysregulation has been implicated in the development of T-cell leukemia, a type of cancer that affects T-cells, a type of immune cell. Additionally, TFDP2's dysregulation has been implicated in the pathogenesis of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, which are characterized by the dysregulation of immune cell function and the induction of inflammation. In conclusion, TFDP2 is a transcription factor that plays a crucial role in regulating cell cycle progression, apoptosis, and cellular responses to stress. Its involvement in the regulation of cell cycle progression and apoptosis has significant implications for our understanding of immune cell development, homeostasis, and the pathogenesis of immune-related disorders. Further research is needed to fully understand the role of TFDP2 in the regulation of immune cell function and the pathogenesis of immune-related disorders. **Relevance to Immunology** TFDP2's involvement in the regulation of cell cycle progression, apoptosis, and cellular responses to stress has significant implications for our understanding of immune cell development, homeostasis, and the pathogenesis of immune-related disorders. TFDP2's dysregulation has been implicated in various immune-related disorders, including cancer, autoimmune diseases, and immunodeficiency diseases. For example, TFDP2's dysregulation has been implicated in the development of T-cell leukemia, a type of cancer that affects T-cells, a type of immune cell. Additionally, TFDP2's dysregulation has been implicated in the pathogenesis of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, which are characterized by the dysregulation of immune cell function and the induction of inflammation. In the context of immunology, TFDP2's involvement in the regulation of cell cycle progression and apoptosis has significant implications for our understanding of immune cell development, homeostasis, and the pathogenesis of immune-related disorders. TFDP2's dysregulation has been implicated in various immune-related disorders, including cancer, autoimmune diseases, and immunodeficiency diseases. Further research is needed to fully understand the role of TFDP2 in the regulation of immune cell function and the pathogenesis of immune-related disorders. **Potential Therapeutic Applications** TFDP2's dysregulation has been implicated in various immune-related disorders, including cancer, autoimmune diseases, and immunodeficiency diseases. Further research is needed to fully understand the role of TFDP2 in the regulation of immune cell function and the pathogenesis of immune-related disorders. However, potential therapeutic applications of TFDP2 include the development of targeted therapies aimed at restoring TFDP2's expression and activity in cells affected by TFDP2 dysregulation. Additionally, TFDP2's involvement in the regulation of cell cycle progression and apoptosis has significant implications for our understanding of immune cell development, homeostasis, and the pathogenesis of immune-related disorders.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Transcription factor Dp-2

Genular Protein ID: 2788587794

Symbol: TFDP2_HUMAN

Name: Transcription factor Dp-2

UniProtKB Accession Codes:

Q14188 B7Z8C8 B7Z8L5 D3DNG1 E9PFC3 F8WAI2 Q13331 Q14187 Q6R754 Q8WU88 Q9UG28

Database IDs:

Citations:

PubMed ID: 7739537

Title: In vivo association of E2F and DP family proteins.

PubMed ID: 7739537

DOI: 10.1128/mcb.15.5.2536

PubMed ID: 7784053

Title: Cloning and characterization of human DP2, a novel dimerization partner of E2F.

PubMed ID: 7784053

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 8755520

Title: DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo.

PubMed ID: 8755520

DOI: 10.1073/pnas.93.15.7594

PubMed ID: 16360038

Title: Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.

PubMed ID: 16360038

DOI: 10.1016/j.cell.2005.09.044

PubMed ID: 17531812

Title: Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence.

PubMed ID: 17531812

DOI: 10.1016/j.molcel.2007.04.015

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20176812

Title: Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.

PubMed ID: 20176812

DOI: 10.1128/mcb.01619-09

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 10090723

Title: Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP.

PubMed ID: 10090723

DOI: 10.1101/gad.13.6.666

Sequence Information:

Length: 446
Mass: 49236
Checksum: 19A6C85BAD61DFF1
Sequence:

MTAKNVGLTS TNAEVRGFID QNLSPTKGNI SFVAFPVSNT NSPTKILPKT LGPINVNVGP 
QMIISTPQRL TSSGSVLIGS PYTPAPAMVT QTHIAEATGW VPGDRKRARK FIDSDFSESK 
RSKKGDKNGK GLRHFSMKVC EKVQRKGTTS YNEVADELVS EFTNSNNHLA ADSAYDQKNI 
RRRVYDALNV LMAMNIISKE KKEIKWIGLP TNSAQECQNL EIEKQRRIER IKQKRAQLQE 
LLLQQIAFKN LVQRNRQNEQ QNQGPPALNS TIQLPFIIIN TSRKTVIDCS ISSDKFEYLF 
NFDNTFEIHD DIEVLKRMGM SFGLESGKCS LEDLKLAKSL VPKALEGYIT DISTGPSWLN 
QGLLLNSTQS VSNLDLTTGA TLPQSSVNQG LCLDAEVALA TGQFLAPNSH QSSSAASHCS 
ESRGETPCSF NDEDEEDDEE DSSSPE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.

Details for: TFDP2

Associated with

Cells (max top 100)

Other Information

In vivo association of E2F and DP family proteins. PubMed ID: 7739537

Cloning and characterization of human DP2, a novel dimerization partner of E2F. PubMed ID: 7784053

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence, annotation and analysis of human chromosome 3. PubMed ID: 16641997

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo. PubMed ID: 8755520

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. PubMed ID: 16360038

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence. PubMed ID: 17531812

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes. PubMed ID: 20176812

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. PubMed ID: 10090723