Details for: TLL1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 31.5810
Cell Significance Index: -12.8300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 11.3849
Cell Significance Index: 1654.9300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 9.1699
Cell Significance Index: 157.1500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 5.8440
Cell Significance Index: -12.7900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 5.7797
Cell Significance Index: 388.6300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 2.1016
Cell Significance Index: 128.8500 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.5854
Cell Significance Index: 17.2100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.5033
Cell Significance Index: 84.3600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.1161
Cell Significance Index: 31.8500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9099
Cell Significance Index: 326.3700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.7376
Cell Significance Index: 33.4400 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.5987
Cell Significance Index: 4.3000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5544
Cell Significance Index: 105.5000 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.5539
Cell Significance Index: 6.2900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4755
Cell Significance Index: 328.8800 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.4373
Cell Significance Index: 6.2900 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.4066
Cell Significance Index: 5.0700 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.3987
Cell Significance Index: 4.1300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.3801
Cell Significance Index: 4.7200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3762
Cell Significance Index: 37.2200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3414
Cell Significance Index: 308.2400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2521
Cell Significance Index: 8.8600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1931
Cell Significance Index: 8.5400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1812
Cell Significance Index: 29.4700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1786
Cell Significance Index: 35.8200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.1288
Cell Significance Index: 3.4400 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: 0.1125
Cell Significance Index: 1.4200 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.1119
Cell Significance Index: 2.7100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0970
Cell Significance Index: 10.5600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0636
Cell Significance Index: 1.5900 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.0629
Cell Significance Index: 0.3800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0542
Cell Significance Index: 34.4100 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0159
Cell Significance Index: 1.1000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0111
Cell Significance Index: 20.8400 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.0066
Cell Significance Index: 0.0800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0017
Cell Significance Index: 0.7400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0007
Cell Significance Index: -0.0200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0055
Cell Significance Index: -8.5300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0059
Cell Significance Index: -10.8300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0096
Cell Significance Index: -4.3400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0096
Cell Significance Index: -12.9900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0157
Cell Significance Index: -0.3400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0172
Cell Significance Index: -13.0400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0185
Cell Significance Index: -13.7300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0193
Cell Significance Index: -14.1600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0215
Cell Significance Index: -13.4100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0223
Cell Significance Index: -12.1800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0235
Cell Significance Index: -4.2400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0239
Cell Significance Index: -13.5000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0291
Cell Significance Index: -1.5300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0345
Cell Significance Index: -9.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0404
Cell Significance Index: -8.0200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0419
Cell Significance Index: -7.1500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0429
Cell Significance Index: -5.5000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0469
Cell Significance Index: -1.1700 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.0547
Cell Significance Index: -0.5200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0557
Cell Significance Index: -6.3800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0593
Cell Significance Index: -8.1500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0597
Cell Significance Index: -2.2600 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0604
Cell Significance Index: -0.9100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0660
Cell Significance Index: -13.9000 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0691
Cell Significance Index: -3.0100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0726
Cell Significance Index: -4.3600 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: -0.0768
Cell Significance Index: -0.6500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0782
Cell Significance Index: -6.0000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0855
Cell Significance Index: -10.5100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1007
Cell Significance Index: -3.2300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1026
Cell Significance Index: -13.2500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1047
Cell Significance Index: -1.5000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1086
Cell Significance Index: -12.6600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1138
Cell Significance Index: -11.8500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1146
Cell Significance Index: -11.7100 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.1151
Cell Significance Index: -0.9500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1322
Cell Significance Index: -2.5800 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.1358
Cell Significance Index: -2.4000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1464
Cell Significance Index: -9.0000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1692
Cell Significance Index: -8.8200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1757
Cell Significance Index: -3.6500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1767
Cell Significance Index: -13.1700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1785
Cell Significance Index: -14.1400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1837
Cell Significance Index: -5.8500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1849
Cell Significance Index: -13.0800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.1869
Cell Significance Index: -4.6600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1931
Cell Significance Index: -4.1100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2159
Cell Significance Index: -7.0700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2347
Cell Significance Index: -12.1900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2545
Cell Significance Index: -11.9600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2649
Cell Significance Index: -9.2800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2653
Cell Significance Index: -12.3700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2734
Cell Significance Index: -7.6400 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.2972
Cell Significance Index: -3.8400 - Cell Name: neuron (CL0000540)
Fold Change: -0.3049
Cell Significance Index: -2.8900 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.3115
Cell Significance Index: -4.0400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3138
Cell Significance Index: -6.6600 - Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
Fold Change: -0.3187
Cell Significance Index: -3.2200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3412
Cell Significance Index: -7.4700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3435
Cell Significance Index: -12.6100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3587
Cell Significance Index: -9.2200 - Cell Name: endothelial stalk cell (CL0002671)
Fold Change: -0.3686
Cell Significance Index: -4.1300 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.3835
Cell Significance Index: -12.1300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2999535011
Symbol: TLL1_HUMAN
Name: Tolloid-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10479448
Title: Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.
PubMed ID: 10479448
PubMed ID: 10896944
Title: Bone morphogenetic protein-1 processes probiglycan.
PubMed ID: 10896944
PubMed ID: 11313359
Title: Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures.
PubMed ID: 11313359
PubMed ID: 18824173
Title: Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.
PubMed ID: 18824173
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 18830233
Title: Mutations in mammalian tolloid-like 1 gene detected in adult patients with ASD.
PubMed ID: 18830233
Sequence Information:
- Length: 1013
- Mass: 114709
- Checksum: 0FDDB6E8E9032DCC
- Sequence:
MGLGTLSPRM LVWLVASGIV FYGELWVCAG LDYDYTFDGN EEDKTETIDY KDPCKAAVFW GDIALDDEDL NIFQIDRTID LTQNPFGNLG HTTGGLGDHA MSKKRGALYQ LIDRIRRIGF GLEQNNTVKG KVPLQFSGQN EKNRVPRAAT SRTERIWPGG VIPYVIGGNF TGSQRAMFKQ AMRHWEKHTC VTFIERSDEE SYIVFTYRPC GCCSYVGRRG NGPQAISIGK NCDKFGIVVH ELGHVIGFWH EHTRPDRDNH VTIIRENIQP GQEYNFLKME PGEVNSLGER YDFDSIMHYA RNTFSRGMFL DTILPSRDDN GIRPAIGQRT RLSKGDIAQA RKLYRCPACG ETLQESNGNL SSPGFPNGYP SYTHCIWRVS VTPGEKIVLN FTTMDLYKSS LCWYDYIEVR DGYWRKSPLL GRFCGDKLPE VLTSTDSRMW IEFRSSSNWV GKGFAAVYEA ICGGEIRKNE GQIQSPNYPD DYRPMKECVW KITVSESYHV GLTFQSFEIE RHDNCAYDYL EVRDGTSENS PLIGRFCGYD KPEDIRSTSN TLWMKFVSDG TVNKAGFAAN FFKEEDECAK PDRGGCEQRC LNTLGSYQCA CEPGYELGPD RRSCEAACGG LLTKLNGTIT TPGWPKEYPP NKNCVWQVVA PTQYRISVKF EFFELEGNEV CKYDYVEIWS GLSSESKLHG KFCGAEVPEV ITSQFNNMRI EFKSDNTVSK KGFKAHFFSD KDECSKDNGG CQHECVNTMG SYMCQCRNGF VLHDNKHDCK EAECEQKIHS PSGLITSPNW PDKYPSRKEC TWEISATPGH RIKLAFSEFE IEQHQECAYD HLEVFDGETE KSPILGRLCG NKIPDPLVAT GNKMFVRFVS DASVQRKGFQ ATHSTECGGR LKAESKPRDL YSHAQFGDNN YPGQVDCEWL LVSERGSRLE LSFQTFEVEE EADCGYDYVE LFDGLDSTAV GLGRFCGSGP PEEIYSIGDS VLIHFHTDDT INKKGFHIRY KSIRYPDTTH TKK
Genular Protein ID: 3736269716
Symbol: B7ZLW3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 1036
- Mass: 117326
- Checksum: E58ACD75248541B0
- Sequence:
MGLGTLSPRM LVWLVASGIV FYGELWVCAG LDYDYTFDGN EEDKTETIDY KDPCKAAVFW GDIALDDEDL NIFQIDRTID LTQNPFGNLG HTTGGLGDHA MSKKRGALYQ LIDRIRRIGF GLEQNNTVKG KVPLQFSGQN EKNRVPRAAT SRTERIWPGG VIPYVIGGNF TGSQRAMFKQ AMRHWEKHTC VTFIERSDEE SYIVFTYRPC GCCSYVGRRG NGPQAISIGK NCDKFGIVVH ELGHVIGFWH EHTRPDRDNH VTIIRENIQP GQEYNFLKME PGEVNSLGER YDFDSIMHYA RNTFSRGMFL DTILPSRDDN GIRPAIGQRT RLSKGDIAQA RKLYRCPACG ETLQESNGNL SSPGFSNGYP SYTHCIWRVS VTPGEKIVLN FTTMDLYKSS LCWYDYIEVR DGYWRKSPLL GRFCGDKLPE VLTSTDSRMW IEFRSSSNWV GKGFAAVYEA ICGGEIRKNE GQIQSPNYPD DYRPMKECVW KITVSESYHV GLTFQSFEQE HQENPGIASK ARESLILIWK PIERHDNCAY DYLEVRDGTS ENSPLIGRFC GYDKPEDIRS TSNTLWMKFV SDGTVNKAGF AANFFKEEDE CAKPDRGGCE QRCLNTLGSY QCACEPGYEL GPDRRSCEAA CGGLLTKLNG TITTPGWPKE YPPNKNCVWQ VVAPTQYRIS VKFEFFELEG NEVCKYDYVE IWSGLSSESK LHGKFCGAEV PEVITSQFNN MRIEFKSDNT VSKKGFKAHF FSDKDECSKD NGGCQHECVN TMGSYMCQCR NGFVLHDNKH DCKEAECEQK IHSPSGLITS PNWPDKYPSR KECTWEISAT PGHRIKLAFS EFEIEQHQEC AYDHLEVFDG ETEKSPILGR LCGNKIPDPL VATGNKMFVR FVSDASVQRK GFQATHSTEC GGRLKAESKP RDLYSHAQFG DNNYPGQVDC EWLLVSERGS RLELSFQTFE VEEEADCGYD YVELFDGLDS TAVGLGRFCG SGPPEEIYSI GDSVLIHFHT DDTINKKGFH IRYKSIRYPD TTHTKK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.