Details for: TLN1

Gene ID: 7094

Symbol: TLN1

Ensembl ID: ENSG00000137076

Description: talin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 288.7906
    Cell Significance Index: -44.9200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 182.1849
    Cell Significance Index: -46.2100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 138.9740
    Cell Significance Index: -57.2500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 127.4808
    Cell Significance Index: -51.7900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 123.3790
    Cell Significance Index: -58.2500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 112.0367
    Cell Significance Index: -57.6300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 55.8580
    Cell Significance Index: -53.3300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.7104
    Cell Significance Index: -52.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 18.6945
    Cell Significance Index: -50.0800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.3385
    Cell Significance Index: -44.0400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.8037
    Cell Significance Index: -54.4700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.0205
    Cell Significance Index: 74.3100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.8121
    Cell Significance Index: 94.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.7815
    Cell Significance Index: 114.9400
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 1.7803
    Cell Significance Index: 8.2200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.7585
    Cell Significance Index: 47.1200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.6541
    Cell Significance Index: 227.1500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.4528
    Cell Significance Index: 87.2200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.3502
    Cell Significance Index: 166.0200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2559
    Cell Significance Index: 136.6100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8942
    Cell Significance Index: 161.2000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.8850
    Cell Significance Index: 104.3700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7886
    Cell Significance Index: 101.0900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.7131
    Cell Significance Index: 19.4100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.7038
    Cell Significance Index: 33.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6081
    Cell Significance Index: 332.1100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5837
    Cell Significance Index: 40.3700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.5830
    Cell Significance Index: 13.4700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.5307
    Cell Significance Index: 14.1700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5145
    Cell Significance Index: 14.8300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4723
    Cell Significance Index: 13.5400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4514
    Cell Significance Index: 199.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4121
    Cell Significance Index: 81.7900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2991
    Cell Significance Index: 8.0000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2797
    Cell Significance Index: 6.0600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2585
    Cell Significance Index: 51.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2284
    Cell Significance Index: 10.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2244
    Cell Significance Index: 10.1700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1768
    Cell Significance Index: 33.6400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1680
    Cell Significance Index: 11.8800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1666
    Cell Significance Index: 16.4800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1604
    Cell Significance Index: 3.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1347
    Cell Significance Index: 10.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1253
    Cell Significance Index: 3.6800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1237
    Cell Significance Index: 85.5600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.1083
    Cell Significance Index: 1.2300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1031
    Cell Significance Index: 93.0600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0922
    Cell Significance Index: 3.2400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0620
    Cell Significance Index: 1.6300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0457
    Cell Significance Index: 86.0400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0324
    Cell Significance Index: 11.6100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0041
    Cell Significance Index: 3.0400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0011
    Cell Significance Index: 0.1800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0035
    Cell Significance Index: -6.4300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0073
    Cell Significance Index: -11.2500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0180
    Cell Significance Index: -2.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0210
    Cell Significance Index: -15.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0243
    Cell Significance Index: -11.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0321
    Cell Significance Index: -43.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0359
    Cell Significance Index: -27.1400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0380
    Cell Significance Index: -3.8900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0428
    Cell Significance Index: -27.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0514
    Cell Significance Index: -32.0800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0546
    Cell Significance Index: -0.3300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0669
    Cell Significance Index: -37.7200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1447
    Cell Significance Index: -30.4800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1558
    Cell Significance Index: -11.6100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1694
    Cell Significance Index: -48.7400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.2083
    Cell Significance Index: -1.7500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2306
    Cell Significance Index: -3.8600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2356
    Cell Significance Index: -27.0000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2774
    Cell Significance Index: -40.3300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3046
    Cell Significance Index: -18.7200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3139
    Cell Significance Index: -36.5800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3305
    Cell Significance Index: -17.1700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3877
    Cell Significance Index: -44.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4297
    Cell Significance Index: -44.7400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5465
    Cell Significance Index: -11.4400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5670
    Cell Significance Index: -44.9100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5993
    Cell Significance Index: -33.6300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7023
    Cell Significance Index: -35.4900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.7256
    Cell Significance Index: -45.7300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7658
    Cell Significance Index: -51.4900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.8436
    Cell Significance Index: -21.5500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.8491
    Cell Significance Index: -23.7300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8539
    Cell Significance Index: -52.3500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.9113
    Cell Significance Index: -14.1000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.9212
    Cell Significance Index: -23.6800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.9256
    Cell Significance Index: -40.9400
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.9432
    Cell Significance Index: -13.2300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.9548
    Cell Significance Index: -33.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9872
    Cell Significance Index: -31.6200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0434
    Cell Significance Index: -54.7800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.1365
    Cell Significance Index: -43.0400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -1.1549
    Cell Significance Index: -14.7900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.1558
    Cell Significance Index: -15.7700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.1908
    Cell Significance Index: -25.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.2433
    Cell Significance Index: -31.0800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.2727
    Cell Significance Index: -11.7200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.2894
    Cell Significance Index: -22.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TLN1 is a multifunctional protein that exhibits several key characteristics: 1. **Cell adhesion**: TLN1 interacts with integrins, which are transmembrane receptors that mediate cell adhesion to the extracellular matrix. 2. **Cytoskeletal organization**: TLN1 interacts with the cytoskeleton, including actin filaments and microtubules, to regulate cell shape, migration, and adhesion. 3. **Signaling**: TLN1 interacts with various signaling molecules, including FAK, Src, and MAPK kinases, to regulate cell signaling pathways. 4. **Regulation of focal adhesion**: TLN1 regulates the assembly and disassembly of focal adhesions, which are critical for cell migration and adhesion. 5. **Interactions with other proteins**: TLN1 interacts with various proteins, including integrins, FAK, and cytoskeletal proteins, to regulate cell adhesion and signaling. **Pathways and Functions** TLN1 is involved in several signaling pathways and cellular processes, including: 1. **Integrin-mediated signaling**: TLN1 interacts with integrins to regulate cell adhesion, migration, and signaling. 2. **MAPK signaling**: TLN1 interacts with MAPK kinases to regulate cell signaling pathways, including proliferation, differentiation, and survival. 3. **FAK signaling**: TLN1 interacts with FAK to regulate cell migration, adhesion, and signaling. 4. **Cytoskeletal organization**: TLN1 regulates cytoskeletal organization, including actin filament dynamics and microtubule stability. 5. **Cell migration**: TLN1 regulates cell migration, including wound healing and tissue repair. **Clinical Significance** TLN1 has been implicated in various diseases and disorders, including: 1. **Cancer**: TLN1 is overexpressed in several types of cancer, including breast, lung, and colon cancer, and is associated with poor prognosis. 2. **Atherosclerosis**: TLN1 is involved in the development of atherosclerosis, a cardiovascular disease characterized by the buildup of plaque in blood vessels. 3. **Wound healing**: TLN1 regulates wound healing, including the migration and adhesion of cells involved in tissue repair. 4. **Neurological disorders**: TLN1 has been implicated in the development of neurological disorders, including Alzheimer's disease and Parkinson's disease. 5. **Inflammatory disorders**: TLN1 is involved in the regulation of inflammation, including the activation of immune cells and the production of pro-inflammatory cytokines. In conclusion, TLN1 is a multifunctional protein that plays a critical role in cell adhesion, migration, and signaling pathways. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of TLN1 in maintaining cellular homeostasis and regulating physiological and pathological processes.

Genular Protein ID: 1414451461

Symbol: TLN1_HUMAN

Name: Talin-1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10610730

Title: Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization, and expression pattern.

PubMed ID: 10610730

DOI: 10.1006/geno.1999.6019

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 28251419

Title: Transcriptome profile of the human placenta.

PubMed ID: 28251419

DOI: 10.1007/s10142-017-0555-y

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10320340

Title: Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.

PubMed ID: 10320340

DOI: 10.1021/bi982395t

PubMed ID: 12422220

Title: Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.

PubMed ID: 12422220

DOI: 10.1038/nature01082

PubMed ID: 12473654

Title: Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha.

PubMed ID: 12473654

DOI: 10.1074/jbc.m211258200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18342854

Title: Identification of a repeated domain within mammalian alpha-synemin that interacts directly with talin.

PubMed ID: 18342854

DOI: 10.1016/j.yexcr.2008.01.034

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21768292

Title: Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition.

PubMed ID: 21768292

DOI: 10.1083/jcb.201007108

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25121749

Title: HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.

PubMed ID: 25121749

DOI: 10.1016/j.chom.2014.07.005

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27895300

Title: THSD1 (thrombospondin type 1 domain containing protein 1) mutation in the pathogenesis of intracranial aneurysm and subarachnoid emorrhage.

PubMed ID: 27895300

DOI: 10.1161/strokeaha.116.014161

PubMed ID: 29069646

Title: The Intracranial Aneurysm Gene THSD1 Connects Endosome Dynamics to Nascent Focal Adhesion Assembly.

PubMed ID: 29069646

DOI: 10.1159/000484298

PubMed ID: 36880935

Title: TLN1 contains a cancer-associated cassette exon that alters talin-1 mechanosensitivity.

PubMed ID: 36880935

DOI: 10.1083/jcb.202209010

PubMed ID: 15070891

Title: Structural basis for amplifying vinculin activation by talin.

PubMed ID: 15070891

DOI: 10.1074/jbc.m403076200

Sequence Information:

  • Length: 2541
  • Mass: 269767
  • Checksum: E21575E9199BBC5C
  • Sequence:
  • MVALSLKISI GNVVKTMQFE PSTMVYDACR IIRERIPEAP AGPPSDFGLF LSDDDPKKGI 
    WLEAGKALDY YMLRNGDTME YRKKQRPLKI RMLDGTVKTI MVDDSKTVTD MLMTICARIG 
    ITNHDEYSLV RELMEEKKEE ITGTLRKDKT LLRDEKKMEK LKQKLHTDDE LNWLDHGRTL 
    REQGVEEHET LLLRRKFFYS DQNVDSRDPV QLNLLYVQAR DDILNGSHPV SFDKACEFAG 
    FQCQIQFGPH NEQKHKAGFL DLKDFLPKEY VKQKGERKIF QAHKNCGQMS EIEAKVRYVK 
    LARSLKTYGV SFFLVKEKMK GKNKLVPRLL GITKECVMRV DEKTKEVIQE WNLTNIKRWA 
    ASPKSFTLDF GDYQDGYYSV QTTEGEQIAQ LIAGYIDIIL KKKKSKDHFG LEGDEESTML 
    EDSVSPKKST VLQQQYNRVG KVEHGSVALP AIMRSGASGP ENFQVGSMPP AQQQITSGQM 
    HRGHMPPLTS AQQALTGTIN SSMQAVQAAQ ATLDDFDTLP PLGQDAASKA WRKNKMDESK 
    HEIHSQVDAI TAGTASVVNL TAGDPAETDY TAVGCAVTTI SSNLTEMSRG VKLLAALLED 
    EGGSGRPLLQ AAKGLAGAVS ELLRSAQPAS AEPRQNLLQA AGNVGQASGE LLQQIGESDT 
    DPHFQDALMQ LAKAVASAAA ALVLKAKSVA QRTEDSGLQT QVIAAATQCA LSTSQLVACT 
    KVVAPTISSP VCQEQLVEAG RLVAKAVEGC VSASQAATED GQLLRGVGAA ATAVTQALNE 
    LLQHVKAHAT GAGPAGRYDQ ATDTILTVTE NIFSSMGDAG EMVRQARILA QATSDLVNAI 
    KADAEGESDL ENSRKLLSAA KILADATAKM VEAAKGAAAH PDSEEQQQRL REAAEGLRMA 
    TNAAAQNAIK KKLVQRLEHA AKQAAASATQ TIAAAQHAAS TPKASAGPQP LLVQSCKAVA 
    EQIPLLVQGV RGSQAQPDSP SAQLALIAAS QSFLQPGGKM VAAAKASVPT IQDQASAMQL 
    SQCAKNLGTA LAELRTAAQK AQEACGPLEM DSALSVVQNL EKDLQEVKAA ARDGKLKPLP 
    GETMEKCTQD LGNSTKAVSS AIAQLLGEVA QGNENYAGIA ARDVAGGLRS LAQAARGVAA 
    LTSDPAVQAI VLDTASDVLD KASSLIEEAK KAAGHPGDPE SQQRLAQVAK AVTQALNRCV 
    SCLPGQRDVD NALRAVGDAS KRLLSDSLPP STGTFQEAQS RLNEAAAGLN QAATELVQAS 
    RGTPQDLARA SGRFGQDFST FLEAGVEMAG QAPSQEDRAQ VVSNLKGISM SSSKLLLAAK 
    ALSTDPAAPN LKSQLAAAAR AVTDSINQLI TMCTQQAPGQ KECDNALREL ETVRELLENP 
    VQPINDMSYF GCLDSVMENS KVLGEAMTGI SQNAKNGNLP EFGDAISTAS KALCGFTEAA 
    AQAAYLVGVS DPNSQAGQQG LVEPTQFARA NQAIQMACQS LGEPGCTQAQ VLSAATIVAK 
    HTSALCNSCR LASARTTNPT AKRQFVQSAK EVANSTANLV KTIKALDGAF TEENRAQCRA 
    ATAPLLEAVD NLSAFASNPE FSSIPAQISP EGRAAMEPIV ISAKTMLESA GGLIQTARAL 
    AVNPRDPPSW SVLAGHSRTV SDSIKKLITS MRDKAPGQLE CETAIAALNS CLRDLDQASL 
    AAVSQQLAPR EGISQEALHT QMLTAVQEIS HLIEPLANAA RAEASQLGHK VSQMAQYFEP 
    LTLAAVGAAS KTLSHPQQMA LLDQTKTLAE SALQLLYTAK EAGGNPKQAA HTQEALEEAV 
    QMMTEAVEDL TTTLNEAASA AGVVGGMVDS ITQAINQLDE GPMGEPEGSF VDYQTTMVRT 
    AKAIAVTVQE MVTKSNTSPE ELGPLANQLT SDYGRLASEA KPAAVAAENE EIGSHIKHRV 
    QELGHGCAAL VTKAGALQCS PSDAYTKKEL IECARRVSEK VSHVLAALQA GNRGTQACIT 
    AASAVSGIIA DLDTTIMFAT AGTLNREGTE TFADHREGIL KTAKVLVEDT KVLVQNAAGS 
    QEKLAQAAQS SVATITRLAD VVKLGAASLG AEDPETQVVL INAVKDVAKA LGDLISATKA 
    AAGKVGDDPA VWQLKNSAKV MVTNVTSLLK TVKAVEDEAT KGTRALEATT EHIRQELAVF 
    CSPEPPAKTS TPEDFIRMTK GITMATAKAV AAGNSCRQED VIATANLSRR AIADMLRACK 
    EAAYHPEVAP DVRLRALHYG RECANGYLEL LDHVLLTLQK PSPELKQQLT GHSKRVAGSV 
    TELIQAAEAM KGTEWVDPED PTVIAENELL GAAAAIEAAA KKLEQLKPRA KPKEADESLN 
    FEEQILEAAK SIAAATSALV KAASAAQREL VAQGKVGAIP ANALDDGQWS QGLISAARMV 
    AAATNNLCEA ANAAVQGHAS QEKLISSAKQ VAASTAQLLV ACKVKADQDS EAMKRLQAAG 
    NAVKRASDNL VKAAQKAAAF EEQENETVVV KEKMVGGIAQ IIAAQEEMLR KERELEEARK 
    KLAQIRQQQY KFLPSELRDE H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.