Details for: TP73

Gene ID: 7161

Symbol: TP73

Ensembl ID: ENSG00000078900

Description: tumor protein p73

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 1.88
    Marker Score: 729
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1170
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.59
    Marker Score: 1460
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.55
    Marker Score: 2945
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.44
    Marker Score: 1435
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 870
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.26
    Marker Score: 855
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.21
    Marker Score: 10549
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 1.2
    Marker Score: 2480
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4817
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.05
    Marker Score: 16475
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71829
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48054
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 508
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30409
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.98
    Marker Score: 1988
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 461
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2413
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.94
    Marker Score: 1542
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 372
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.92
    Marker Score: 5267
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.92
    Marker Score: 3172
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2740
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 324
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.88
    Marker Score: 1678.5
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5288
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.86
    Marker Score: 407
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.78
    Marker Score: 598
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1262
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 709
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 395
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.74
    Marker Score: 235
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 461
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 177
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.65
    Marker Score: 391
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.57
    Marker Score: 1333
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.55
    Marker Score: 147
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.55
    Marker Score: 201
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.54
    Marker Score: 172
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.54
    Marker Score: 417
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.52
    Marker Score: 250
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.51
    Marker Score: 1871
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.49
    Marker Score: 472
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.48
    Marker Score: 155
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.46
    Marker Score: 276
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.44
    Marker Score: 185
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.44
    Marker Score: 202
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.44
    Marker Score: 198
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.39
    Marker Score: 443
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 370
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.35
    Marker Score: 109
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.33
    Marker Score: 86
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.32
    Marker Score: 142
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.3
    Marker Score: 393
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.29
    Marker Score: 386
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.27
    Marker Score: 112
  • Cell Name: epithelial cell of thymus (CL0002293)
    Fold Change: 0.26
    Marker Score: 83
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.22
    Marker Score: 64
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.22
    Marker Score: 1658
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 74
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: 0.22
    Marker Score: 690
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.19
    Marker Score: 95
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.19
    Marker Score: 67
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: 0.19
    Marker Score: 125
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.17
    Marker Score: 5975
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.17
    Marker Score: 42
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.16
    Marker Score: 288
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.16
    Marker Score: 180.5
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.16
    Marker Score: 110
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.16
    Marker Score: 445
  • Cell Name: IgG plasma cell (CL0000985)
    Fold Change: 0.15
    Marker Score: 64
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 0.15
    Marker Score: 162
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.14
    Marker Score: 53
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.14
    Marker Score: 80
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.13
    Marker Score: 88
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.13
    Marker Score: 118
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.13
    Marker Score: 114
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.13
    Marker Score: 363
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.13
    Marker Score: 140
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.12
    Marker Score: 67
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.12
    Marker Score: 125
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.11
    Marker Score: 139
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 0.11
    Marker Score: 30
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.11
    Marker Score: 322
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.1
    Marker Score: 1368
  • Cell Name: IgA plasmablast (CL0000984)
    Fold Change: 0.1
    Marker Score: 26
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.1
    Marker Score: 93
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.1
    Marker Score: 19
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 0.1
    Marker Score: 59
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 0.1
    Marker Score: 55
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.1
    Marker Score: 48
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.09
    Marker Score: 122
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.09
    Marker Score: 58
  • Cell Name: respiratory basal cell (CL0002633)
    Fold Change: 0.09
    Marker Score: 133
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.09
    Marker Score: 80
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.09
    Marker Score: 62
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.09
    Marker Score: 41
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.09
    Marker Score: 22
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.09
    Marker Score: 152

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Other Information

**Key Characteristics:** TP73 is a member of the p53 family of proteins, which are crucial regulators of cell growth, differentiation, and survival. TP73 shares similarities with TP53, but its expression and function are distinct. TP73 is a transcriptional activator that binds to specific DNA sequences, influencing the expression of various genes involved in apoptosis, cell cycle regulation, and immune response. Its expression is tissue-specific, with significant levels found in neuroendocrine cells, colon goblet cells, and other epithelial tissues. **Pathways and Functions:** TP73 is involved in several key pathways, including: 1. **Apoptosis**: TP73 regulates the expression of pro-apoptotic and anti-apoptotic genes, influencing the intrinsic apoptotic signaling pathway in response to DNA damage. 2. **Cell Cycle Regulation**: TP73 modulates the expression of cell cycle regulators, including p21 and p27, to control cell proliferation and prevent tumor formation. 3. **Transcriptional Control**: TP73 binds to specific DNA sequences, influencing the expression of genes involved in immune response, cell differentiation, and development. 4. **DNA Damage Response**: TP73 interacts with other proteins, such as MDM2 and p53, to regulate the response to DNA damage and prevent genomic instability. 5. **Immune Regulation**: TP73 is expressed in immune cells, including T cells and dendritic cells, and regulates the expression of genes involved in immune response, including cytokines and chemokines. **Clinical Significance:** TP73's role in immune regulation and cancer makes it a potential therapeutic target. Abnormal expression of TP73 has been linked to various cancers, including leukemia, lymphoma, and breast cancer. TP73's ability to regulate apoptosis and cell cycle makes it a potential target for cancer therapy. Additionally, TP73's expression in immune cells suggests its potential role in modulating the immune response in autoimmune diseases and cancer. **Implications for Immune Regulation:** TP73's involvement in immune regulation highlights its potential role in maintaining immune homeostasis. Dysregulation of TP73 expression may contribute to autoimmune diseases and cancer. Understanding TP73's function in immune regulation may provide insights into the development of novel immunotherapies and cancer treatments. **Conclusion:** In conclusion, TP73 is a multifunctional protein involved in various cellular processes, including apoptosis, cell cycle regulation, and transcriptional control. Its expression and function are distinct from TP53, and its involvement in immune regulation and cancer makes it a potential therapeutic target. Further research is needed to fully understand TP73's role in immune regulation and cancer, but its multifaceted function highlights its importance in maintaining immune homeostasis and preventing disease.

Genular Protein ID: 948976148

Symbol: P73_HUMAN

Name: Tumor protein p73

UniProtKB Accession Codes:

O15350 B7Z7J4 B7Z8Z1 B7Z9C1 C9J521 O15351 Q17RN8 Q5TBV5 Q5TBV6 Q8NHW9 Q8TDY5 Q8TDY6 Q9NTK8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 8 CDD 2 CTD 1 ChEBI 5 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 4 ELM 1 EMBL 39 EMDB 1 EPD 1 Ensembl 10 EvolutionaryTrace 1 ExpressionAtlas 1 GO 42 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 31 PDBsum 23 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 11 Pumba 1 RNAct 1 Reactome 7 RefSeq 13 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9288759

Title: Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.

PubMed ID: 9288759

DOI: 10.1016/s0092-8674(00)80540-1

PubMed ID: 9721206

Title: Genomic organization and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletions.

PubMed ID: 9721206

DOI: 10.1006/geno.1998.5387

PubMed ID: 9802988

Title: Two new p73 splice variants, gamma and delta, with different transcriptional activity.

PubMed ID: 9802988

DOI: 10.1084/jem.188.9.1763

PubMed ID: 10381648

Title: Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants epsilon and zeta.

PubMed ID: 10381648

DOI: 10.1038/sj.cdd.4400521

PubMed ID: 10362363

Title: Mutational analysis of p73 and p53 in human cancer cell lines.

PubMed ID: 10362363

DOI: 10.1038/sj.onc.1202677

PubMed ID: 11753569

Title: Human DeltaNp73 regulates a dominant negative feedback loop for TAp73 and p53.

PubMed ID: 11753569

DOI: 10.1038/sj.cdd.4400962

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10391251

Title: p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.

PubMed ID: 10391251

DOI: 10.1038/21704

PubMed ID: 10203277

Title: The emerging p53 gene family.

PubMed ID: 10203277

DOI: 10.1093/jnci/91.7.594

PubMed ID: 10961991

Title: Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif.

PubMed ID: 10961991

DOI: 10.1074/jbc.m004293200

PubMed ID: 11706030

Title: Differential effect of ik3-1/cables on p53- and p73-induced cell death.

PubMed ID: 11706030

DOI: 10.1074/jbc.m108535200

PubMed ID: 11925430

Title: Identification and characterization of HIPK2 interacting with p73 and modulating functions of the p53 family in vivo.

PubMed ID: 11925430

DOI: 10.1074/jbc.m200153200

PubMed ID: 12890487

Title: A novel HECT-type E3 ubiquitin ligase, NEDL2, stabilizes p73 and enhances its transcriptional activity.

PubMed ID: 12890487

DOI: 10.1016/s0006-291x(03)01347-0

PubMed ID: 15070730

Title: Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.

PubMed ID: 15070730

DOI: 10.1073/pnas.0400805101

PubMed ID: 15558019

Title: Protein stability and function of p73 are modulated by a physical interaction with RanBPM in mammalian cultured cells.

PubMed ID: 15558019

DOI: 10.1038/sj.onc.1208257

PubMed ID: 16461361

Title: Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.

PubMed ID: 16461361

DOI: 10.1083/jcb.200509132

PubMed ID: 18418051

Title: p73-mediated transcriptional activity is negatively regulated by polo-like kinase 1.

PubMed ID: 18418051

DOI: 10.4161/cc.7.9.5777

PubMed ID: 18174154

Title: Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation.

PubMed ID: 18174154

DOI: 10.1074/jbc.m710608200

PubMed ID: 17535448

Title: Regulation of p73 by Hck through kinase-dependent and independent mechanisms.

PubMed ID: 17535448

DOI: 10.1186/1471-2199-8-45

PubMed ID: 18280240

Title: Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage.

PubMed ID: 18280240

DOI: 10.1016/j.molcel.2007.12.022

PubMed ID: 19490146

Title: Plk3 inhibits pro-apoptotic activity of p73 through physical interaction and phosphorylation.

PubMed ID: 19490146

DOI: 10.1111/j.1365-2443.2009.01309.x

PubMed ID: 19581926

Title: The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.

PubMed ID: 19581926

DOI: 10.1038/onc.2009.177

PubMed ID: 21994467

Title: Pirh2, a ubiquitin E3 ligase, inhibits p73 transcriptional activity by promoting its ubiquitination.

PubMed ID: 21994467

DOI: 10.1158/1541-7786.mcr-11-0157

PubMed ID: 24314664

Title: Epstein-Barr virus nuclear antigen 3C interact with p73: Interplay between a viral oncoprotein and cellular tumor suppressor.

PubMed ID: 24314664

DOI: 10.1016/j.virol.2013.10.023

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 28291250

Title: Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism.

PubMed ID: 28291250

DOI: 10.1038/srep44532

PubMed ID: 10449409

Title: Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.

PubMed ID: 10449409

DOI: 10.1093/emboj/18.16.4438

PubMed ID: 34077761

Title: Mutations in TP73 cause impaired mucociliary clearance and lissencephaly.

PubMed ID: 34077761

DOI: 10.1016/j.ajhg.2021.05.002

Sequence Information:

  • Length: 636
  • Mass: 69623
  • Checksum: A467493C5D93EEE0
  • Sequence:
    • MAQSTATSPD GGTTFEHLWS SLEPDSTYFD LPQSSRGNNE VVGGTDSSMD VFHLEGMTTS 
VMAQFNLLSS TMDQMSSRAA SASPYTPEHA ASVPTHSPYA QPSSTFDTMS PAPVIPSNTD 
YPGPHHFEVT FQQSSTAKSA TWTYSPLLKK LYCQIAKTCP IQIKVSTPPP PGTAIRAMPV 
YKKAEHVTDV VKRCPNHELG RDFNEGQSAP ASHLIRVEGN NLSQYVDDPV TGRQSVVVPY 
EPPQVGTEFT TILYNFMCNS SCVGGMNRRP ILIIITLEMR DGQVLGRRSF EGRICACPGR 
DRKADEDHYR EQQALNESSA KNGAASKRAF KQSPPAVPAL GAGVKKRRHG DEDTYYLQVR 
GRENFEILMK LKESLELMEL VPQPLVDSYR QQQQLLQRPS HLQPPSYGPV LSPMNKVHGG 
MNKLPSVNQL VGQPPPHSSA ATPNLGPVGP GMLNNHGHAV PANGEMSSSH SAQSMVSGSH 
CTPPPPYHAD PSLVSFLTGL GCPNCIEYFT SQGLQSIYHL QNLTIEDLGA LKIPEQYRMT 
IWRGLQDLKQ GHDYSTAQQL LRSSNAATIS IGGSGELQRQ RVMEAVHFRV RHTITIPNRG 
GPGGGPDEWA DFGFDLPDCK ARKQPIKEEF TEAEIH

Genular Protein ID: 988653164

Symbol: A0A0C4DFW9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DFW9

Database IDs:

ARBA 6 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 5 ChiTaRS 1 DNASU 1 EMBL 3 EPD 1 Ensembl 2 GO 9 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 1 Pfam 4 Proteomes 2 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 426
  • Mass: 47696
  • Checksum: 18BB215365AED592
  • Sequence:
    • MLYVGDPARH LATAQFNLLS STMDQMSSRA ASASPYTPEH AASVPTHSPY AQPSSTFDTM 
SPAPVIPSNT DYPGPHHFEV TFQQSSTAKS ATWTYSPLLK KLYCQIAKTC PIQIKVSTPP 
PPGTAIRAMP VYKKAEHVTD VVKRCPNHEL GRDFNEGQSA PASHLIRVEG NNLSQYVDDP 
VTGRQSVVVP YEPPQVGTEF TTILYNFMCN SSCVGGMNRR PILIIITLEM RDGQVLGRRS 
FEGRICACPG RDRKADEDHY REQQALNESS AKNGAASKRA FKQSPPAVPA LGAGVKKRRH 
GDEDTYYLQV RGRENFEILM KLKESLELME LVPQPLVDSY RQQQQLLQRP PRDAQQPWPR 
SASQRRDEQQ PQRPVHGLGV PLHSATPLPR RPQPRQFFNR IGVSKLHRVF HLPRVTEHLP 
PAEPDH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.