Details for: TRPC6

Gene ID: 7225

Symbol: TRPC6

Ensembl ID: ENSG00000137672

Description: transient receptor potential cation channel subfamily C member 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 72.0048
    Cell Significance Index: -11.2000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 24.6546
    Cell Significance Index: -11.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.8434
    Cell Significance Index: -11.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.3474
    Cell Significance Index: 88.8900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.2409
    Cell Significance Index: 99.1200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.9053
    Cell Significance Index: 116.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6128
    Cell Significance Index: 116.6300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.5319
    Cell Significance Index: 7.9700
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.4942
    Cell Significance Index: 7.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4149
    Cell Significance Index: 41.0400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3566
    Cell Significance Index: 322.0300
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.3250
    Cell Significance Index: 2.7300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.3029
    Cell Significance Index: 4.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1994
    Cell Significance Index: 32.4400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1448
    Cell Significance Index: 2.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1313
    Cell Significance Index: 14.2900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1054
    Cell Significance Index: 6.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1025
    Cell Significance Index: 36.7600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0929
    Cell Significance Index: 1.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0823
    Cell Significance Index: 2.3700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0799
    Cell Significance Index: 1.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0715
    Cell Significance Index: 12.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0651
    Cell Significance Index: 4.3800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0490
    Cell Significance Index: 33.8800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0435
    Cell Significance Index: 8.6300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0403
    Cell Significance Index: 8.0800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0369
    Cell Significance Index: 4.5400
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0268
    Cell Significance Index: 0.6200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0227
    Cell Significance Index: 12.4100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0221
    Cell Significance Index: 3.0300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0160
    Cell Significance Index: 1.1100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0037
    Cell Significance Index: 6.9900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0004
    Cell Significance Index: -0.6800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0010
    Cell Significance Index: -1.6100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0017
    Cell Significance Index: -0.0600
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0022
    Cell Significance Index: -0.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0023
    Cell Significance Index: -3.1300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0066
    Cell Significance Index: -0.1000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0084
    Cell Significance Index: -0.2100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0095
    Cell Significance Index: -0.4300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0097
    Cell Significance Index: -0.1900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0101
    Cell Significance Index: -0.2000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0117
    Cell Significance Index: -0.7000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0139
    Cell Significance Index: -10.1600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0144
    Cell Significance Index: -10.9100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0148
    Cell Significance Index: -9.4000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0158
    Cell Significance Index: -11.6900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0169
    Cell Significance Index: -7.6900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0198
    Cell Significance Index: -12.3800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0214
    Cell Significance Index: -12.0600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0229
    Cell Significance Index: -0.5500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0240
    Cell Significance Index: -10.6300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0305
    Cell Significance Index: -8.7700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0407
    Cell Significance Index: -5.9100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0474
    Cell Significance Index: -1.0100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0512
    Cell Significance Index: -0.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0538
    Cell Significance Index: -9.1900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0540
    Cell Significance Index: -0.7000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0582
    Cell Significance Index: -12.2600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0668
    Cell Significance Index: -7.6600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0715
    Cell Significance Index: -1.4400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0740
    Cell Significance Index: -9.4900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0805
    Cell Significance Index: -1.3800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0897
    Cell Significance Index: -9.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0913
    Cell Significance Index: -7.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0921
    Cell Significance Index: -11.9000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0927
    Cell Significance Index: -10.8000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1014
    Cell Significance Index: -10.5600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1309
    Cell Significance Index: -4.1700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1339
    Cell Significance Index: -7.0300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1463
    Cell Significance Index: -10.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1481
    Cell Significance Index: -11.7300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1622
    Cell Significance Index: -12.0900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1691
    Cell Significance Index: -9.4900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1784
    Cell Significance Index: -5.8400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1844
    Cell Significance Index: -8.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1876
    Cell Significance Index: -9.7700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1942
    Cell Significance Index: -10.0900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1944
    Cell Significance Index: -6.1500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2026
    Cell Significance Index: -6.4900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2232
    Cell Significance Index: -6.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2314
    Cell Significance Index: -10.7900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2529
    Cell Significance Index: -8.8600
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.2558
    Cell Significance Index: -1.8600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2583
    Cell Significance Index: -6.6400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2684
    Cell Significance Index: -7.3100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2865
    Cell Significance Index: -6.0800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2866
    Cell Significance Index: -9.9600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2879
    Cell Significance Index: -4.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2959
    Cell Significance Index: -7.9000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3002
    Cell Significance Index: -11.0200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3018
    Cell Significance Index: -8.8900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3144
    Cell Significance Index: -7.8400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3253
    Cell Significance Index: -14.1400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3299
    Cell Significance Index: -9.2200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3426
    Cell Significance Index: -9.1800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3499
    Cell Significance Index: -9.3600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3500
    Cell Significance Index: -7.2600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3606
    Cell Significance Index: -7.7900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3687
    Cell Significance Index: -18.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The TRPC6 channel is a non-selective cation channel that allows the influx of multiple cations, including calcium, magnesium, and sodium, into cells. It is characterized by its ability to respond to various stimuli, including changes in intracellular calcium concentrations, and its involvement in several signaling pathways. The TRPC6 channel exhibits a unique structure, consisting of six transmembrane domains and a pore region, which enables it to form homodimers and interact with other proteins. **Pathways and Functions** The TRPC6 channel is involved in various cellular processes, including: 1. **Axon guidance**: TRPC6 channels play a crucial role in axon guidance during development, regulating the migration and growth of neurons. 2. **Calcium signaling**: TRPC6 channels are activated by increases in intracellular calcium concentrations, triggering a cascade of signaling events that regulate cellular responses. 3. **Platelet activation**: TRPC6 channels are involved in platelet activation and aggregation, influencing blood clotting and cardiovascular health. 4. **Neurotransmission**: TRPC6 channels modulate neurotransmitter release and synaptic plasticity in the nervous system. 5. **Cell differentiation**: TRPC6 channels regulate cell differentiation and survival in various cell types, including photoreceptors and dopaminergic neurons. **Clinical Significance** Dysregulation of the TRPC6 channel has been implicated in several diseases, including: 1. **Retinitis pigmentosa**: Mutations in the TRPC6 gene have been associated with retinitis pigmentosa, a genetic disorder affecting photoreceptor cells. 2. **Cardiovascular disease**: TRPC6 channel dysfunction has been linked to cardiovascular disease, including hypertension and atherosclerosis. 3. **Neurological disorders**: TRPC6 channel dysregulation has been implicated in neurological disorders, such as Parkinson's disease and autism spectrum disorder. 4. **Cancer**: TRPC6 channels have been found to be overexpressed in various types of cancer, including breast and lung cancer. In summary, the TRPC6 gene encodes for a critical component of ion channels that regulate calcium homeostasis and are involved in various cellular processes, including axon guidance, calcium signaling, and platelet activation. Dysregulation of the TRPC6 channel has been implicated in several diseases, highlighting the importance of this gene in human health and disease.

Genular Protein ID: 4176401046

Symbol: TRPC6_HUMAN

Name: Short transient receptor potential channel 6

UniProtKB Accession Codes:

Q9Y210 Q52M59 Q9HCW3 Q9NQA8 Q9NQA9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EMBL 8 EMDB 6 Ensembl 3 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 4 RefSeq 2 SABIO-RK 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9930701

Title: Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.

PubMed ID: 9930701

DOI: 10.1038/16711

PubMed ID: 9925922

Title: Identification and assignment of the human transient receptor potential channel 6 gene TRPC6 to chromosome 11q21-22.

PubMed ID: 9925922

DOI: 10.1159/000015165

PubMed ID: 10816590

Title: TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells.

PubMed ID: 10816590

DOI: 10.1074/jbc.m003408200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12970363

Title: N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.

PubMed ID: 12970363

DOI: 10.1074/jbc.m302983200

PubMed ID: 15757897

Title: MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

PubMed ID: 15757897

DOI: 10.1074/jbc.m500391200

PubMed ID: 17850865

Title: RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC.

PubMed ID: 17850865

DOI: 10.1016/j.ceca.2007.07.009

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 15924139

Title: TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.

PubMed ID: 15924139

DOI: 10.1038/ng1592

PubMed ID: 15879175

Title: A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis.

PubMed ID: 15879175

DOI: 10.1126/science.1106215

PubMed ID: 19124028

Title: Identification and functional analysis of a novel TRPC6 mutation associated with late onset familial focal segmental glomerulosclerosis in Chinese patients.

PubMed ID: 19124028

DOI: 10.1016/j.mrfmmm.2008.11.021

PubMed ID: 19458060

Title: TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis.

PubMed ID: 19458060

DOI: 10.1093/ndt/gfp229

PubMed ID: 19936226

Title: A novel TRPC6 mutation that causes childhood FSGS.

PubMed ID: 19936226

DOI: 10.1371/journal.pone.0007771

PubMed ID: 20798252

Title: Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndrome.

PubMed ID: 20798252

DOI: 10.2215/cjn.01190210

PubMed ID: 21734084

Title: TRPC6 mutations in children with steroid-resistant nephrotic syndrome and atypical phenotype.

PubMed ID: 21734084

DOI: 10.2215/cjn.07830910

PubMed ID: 22732337

Title: Mutations in podocyte genes are a rare cause of primary FSGS associated with ESRD in adult patients.

PubMed ID: 22732337

DOI: 10.5414/cn107320

PubMed ID: 21511817

Title: TRPC6 gene variants in Turkish children with steroid-resistant nephrotic syndrome.

PubMed ID: 21511817

DOI: 10.1093/ndt/gfr202

PubMed ID: 23014460

Title: Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis.

PubMed ID: 23014460

DOI: 10.1038/ki.2012.349

PubMed ID: 23291369

Title: New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis.

PubMed ID: 23291369

DOI: 10.1093/ndt/gfs572

PubMed ID: 26892346

Title: TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.

PubMed ID: 26892346

DOI: 10.1681/asn.2015030318

Sequence Information:

  • Length: 931
  • Mass: 106326
  • Checksum: 7C955C2B0389AC47
  • Sequence:
    • MSQSPAFGPR RGSSPRGAAG AAARRNESQD YLLMDSELGE DGCPQAPLPC YGYYPCFRGS 
DNRLAHRRQT VLREKGRRLA NRGPAYMFSD RSTSLSIEEE RFLDAAEYGN IPVVRKMLEE 
CHSLNVNCVD YMGQNALQLA VANEHLEITE LLLKKENLSR VGDALLLAIS KGYVRIVEAI 
LSHPAFAEGK RLATSPSQSE LQQDDFYAYD EDGTRFSHDV TPIILAAHCQ EYEIVHTLLR 
KGARIERPHD YFCKCNDCNQ KQKHDSFSHS RSRINAYKGL ASPAYLSLSS EDPVMTALEL 
SNELAVLANI EKEFKNDYKK LSMQCKDFVV GLLDLCRNTE EVEAILNGDV ETLQSGDHGR 
PNLSRLKLAI KYEVKKFVAH PNCQQQLLSI WYENLSGLRQ QTMAVKFLVV LAVAIGLPFL 
ALIYWFAPCS KMGKIMRGPF MKFVAHAASF TIFLGLLVMN AADRFEGTKL LPNETSTDNA 
KQLFRMKTSC FSWMEMLIIS WVIGMIWAEC KEIWTQGPKE YLFELWNMLD FGMLAIFAAS 
FIARFMAFWH ASKAQSIIDA NDTLKDLTKV TLGDNVKYYN LARIKWDPSD PQIISEGLYA 
IAVVLSFSRI AYILPANESF GPLQISLGRT VKDIFKFMVI FIMVFVAFMI GMFNLYSYYI 
GAKQNEAFTT VEESFKTLFW AIFGLSEVKS VVINYNHKFI ENIGYVLYGV YNVTMVIVLL 
NMLIAMINSS FQEIEDDADV EWKFARAKLW FSYFEEGRTL PVPFNLVPSP KSLFYLLLKL 
KKWISELFQG HKKGFQEDAE MNKINEEKKL GILGSHEDLS KLSLDKKQVG HNKQPSIRSS 
EDFHLNSFNN PPRQYQKIMK RLIKRYVLQA QIDKESDEVN EGELKEIKQD ISSLRYELLE 
EKSQNTEDLA ELIRELGEKL SMEPNQEETN R

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.