Details for: TXNRD1

Gene ID: 7296

Symbol: TXNRD1

Ensembl ID: ENSG00000198431

Description: thioredoxin reductase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 343.9514
    Cell Significance Index: -53.5000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 211.9117
    Cell Significance Index: -53.7500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 146.4021
    Cell Significance Index: -60.3100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 126.5561
    Cell Significance Index: -59.7500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 119.0625
    Cell Significance Index: -48.3700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 50.8933
    Cell Significance Index: -48.5900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.3071
    Cell Significance Index: -54.4000
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 16.2388
    Cell Significance Index: 36.6100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 14.9593
    Cell Significance Index: -59.0300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 12.6683
    Cell Significance Index: -38.9100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 11.4378
    Cell Significance Index: 69.1100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.0424
    Cell Significance Index: -19.7900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 5.6887
    Cell Significance Index: 152.4300
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 5.6350
    Cell Significance Index: 40.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 4.5306
    Cell Significance Index: 899.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.0599
    Cell Significance Index: 81.7100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 3.0380
    Cell Significance Index: 41.4500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.8710
    Cell Significance Index: 25.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.7306
    Cell Significance Index: 209.5500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.2055
    Cell Significance Index: 152.5200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.1754
    Cell Significance Index: 62.3600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.0779
    Cell Significance Index: 56.5600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.7246
    Cell Significance Index: 49.6900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.7239
    Cell Significance Index: 11.6800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.6986
    Cell Significance Index: 47.4700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.5688
    Cell Significance Index: 255.1600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.5421
    Cell Significance Index: 33.4100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2239
    Cell Significance Index: 245.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1888
    Cell Significance Index: 71.3700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0917
    Cell Significance Index: 596.1800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0793
    Cell Significance Index: 117.4000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6899
    Cell Significance Index: 247.4500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6541
    Cell Significance Index: 33.9800
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.6500
    Cell Significance Index: 4.0100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6468
    Cell Significance Index: 123.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.5892
    Cell Significance Index: 374.1900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5172
    Cell Significance Index: 357.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4512
    Cell Significance Index: 21.2100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3994
    Cell Significance Index: 51.6000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3760
    Cell Significance Index: 51.6400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3144
    Cell Significance Index: 38.6600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2994
    Cell Significance Index: 563.6500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2964
    Cell Significance Index: 34.9600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2622
    Cell Significance Index: 236.7500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2599
    Cell Significance Index: 117.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2288
    Cell Significance Index: 101.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2283
    Cell Significance Index: 12.8100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2201
    Cell Significance Index: 39.6700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.2172
    Cell Significance Index: 4.2400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1819
    Cell Significance Index: 2.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1789
    Cell Significance Index: 8.1100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1579
    Cell Significance Index: 10.6200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1205
    Cell Significance Index: 8.5200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0894
    Cell Significance Index: 1.3200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0892
    Cell Significance Index: 1.9000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0697
    Cell Significance Index: 2.4500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0641
    Cell Significance Index: 1.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0496
    Cell Significance Index: 91.4900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0429
    Cell Significance Index: 2.7700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0310
    Cell Significance Index: 47.6600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0185
    Cell Significance Index: 25.1100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0118
    Cell Significance Index: 2.0100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0016
    Cell Significance Index: -0.2100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0086
    Cell Significance Index: -0.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0110
    Cell Significance Index: -8.3100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0161
    Cell Significance Index: -10.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0163
    Cell Significance Index: -12.0400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0338
    Cell Significance Index: -24.7700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0636
    Cell Significance Index: -35.8700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.1336
    Cell Significance Index: -13.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1386
    Cell Significance Index: -14.1600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1465
    Cell Significance Index: -30.8600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1484
    Cell Significance Index: -6.9200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1543
    Cell Significance Index: -11.5000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1595
    Cell Significance Index: -45.8900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1668
    Cell Significance Index: -1.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1695
    Cell Significance Index: -19.7500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1781
    Cell Significance Index: -25.8900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1844
    Cell Significance Index: -4.7400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2220
    Cell Significance Index: -25.3400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3078
    Cell Significance Index: -35.2600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3174
    Cell Significance Index: -5.4400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3511
    Cell Significance Index: -18.2900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3674
    Cell Significance Index: -38.2600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4594
    Cell Significance Index: -20.3200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5593
    Cell Significance Index: -35.2500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5644
    Cell Significance Index: -44.7000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5661
    Cell Significance Index: -8.1300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.5775
    Cell Significance Index: -21.8700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.6021
    Cell Significance Index: -8.6600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6313
    Cell Significance Index: -16.6000
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.6319
    Cell Significance Index: -14.6000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6495
    Cell Significance Index: -22.5700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.7253
    Cell Significance Index: -18.5300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7342
    Cell Significance Index: -17.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7462
    Cell Significance Index: -39.1800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7914
    Cell Significance Index: -48.5200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.8011
    Cell Significance Index: -22.8600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.8189
    Cell Significance Index: -20.4700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.9708
    Cell Significance Index: -28.5100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TXNRD1 is a NADPH-dependent enzyme that catalyzes the reduction of thioredoxin, a small protein that contains a cysteine residue. The enzyme is composed of two subunits: a large subunit (TXNRD1A) and a small subunit (TXNRD1B). TXNRD1 is highly specific for thioredoxin, with a low affinity for other reducing agents. The enzyme is also sensitive to NADPH levels, with optimal activity observed at high NADPH concentrations. **Pathways and Functions:** TXNRD1 plays a central role in maintaining cellular redox homeostasis by regulating the activity of thioredoxin, a key player in the thioredoxin system. The thioredoxin system is involved in various cellular processes, including: 1. **Cellular stress response**: TXNRD1 helps to protect cells against oxidative stress by reducing thioredoxin, which in turn activates various antioxidant enzymes, such as glutathione peroxidase and superoxide dismutase. 2. **Cell proliferation and differentiation**: TXNRD1 regulates the activity of thioredoxin, which is involved in the regulation of cell cycle progression and differentiation. 3. **Apoptosis regulation**: TXNRD1 has been shown to regulate the activity of thioredoxin, which is involved in the regulation of apoptosis (programmed cell death). 4. **Metabolism**: TXNRD1 is involved in the regulation of various metabolic pathways, including lipid metabolism and amino acid metabolism. **Clinical Significance:** Dysregulation of TXNRD1 has been implicated in various diseases, including: 1. **Cancer**: TXNRD1 has been shown to be overexpressed in various types of cancer, including breast, prostate, and lung cancer. 2. **Cardiovascular disease**: TXNRD1 has been shown to play a role in the development of cardiovascular disease by regulating the activity of thioredoxin, which is involved in the regulation of blood pressure and vascular tone. 3. **Neurodegenerative disorders**: TXNRD1 has been implicated in the development of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease, by regulating the activity of thioredoxin, which is involved in the regulation of oxidative stress and inflammation. In conclusion, TXNRD1 is a crucial enzyme involved in maintaining cellular redox homeostasis. Its dysregulation has been implicated in various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. Further research is needed to fully elucidate the role of TXNRD1 in human health and disease.

Genular Protein ID: 3908787599

Symbol: TRXR1_HUMAN

Name: Gene associated with retinoic and interferon-induced mortality 12 protein

UniProtKB Accession Codes:

Q16881 B7Z1F4 B7Z3Y8 B7Z904 E9PMY9 F5H780 Q6FI31 Q6VB40 Q6VB41 Q6VB42 Q6VBP2 Q6VBP3 Q6VBP4 Q6VBP5 Q6VBP9 Q6VBQ0 Q6YNQ1 Q76P53 Q7LA96 Q8WVC8 Q99475 Q9UES8 Q9UH79

Database IDs:

AGR 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChEBI 29 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 10 DrugCentral 1 EC 2 EMBL 30 EMDB 1 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 8 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 8 RefSeq 7 Rhea 6 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7589432

Title: Cloning and sequencing of a human thioredoxin reductase.

PubMed ID: 7589432

DOI: 10.1016/0014-5793(95)01003-w

PubMed ID: 8999974

Title: Cloning and characterization of a novel oxidoreductase KDRF from a human bone marrow-derived stromal cell line KM-102.

PubMed ID: 8999974

DOI: 10.1074/jbc.272.4.2570

PubMed ID: 9774665

Title: Thioredoxin reductase mediates cell death effects of the combination of beta interferon and retinoic acid.

PubMed ID: 9774665

DOI: 10.1128/mcb.18.11.6493

PubMed ID: 14980707

Title: Evidence for intriguingly complex transcription of human thioredoxin reductase 1.

PubMed ID: 14980707

DOI: 10.1016/j.freeradbiomed.2003.12.004

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8650234

Title: Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

PubMed ID: 8650234

DOI: 10.1073/pnas.93.12.6146

PubMed ID: 8577704

Title: A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity.

PubMed ID: 8577704

DOI: 10.1073/pnas.93.3.1006

PubMed ID: 10849437

Title: Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations.

PubMed ID: 10849437

DOI: 10.1074/jbc.m000690200

PubMed ID: 15379556

Title: Alternative splicing involving the thioredoxin reductase module in mammals: a glutaredoxin-containing thioredoxin reductase 1.

PubMed ID: 15379556

DOI: 10.1021/bi048478t

PubMed ID: 15199063

Title: An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling.

PubMed ID: 15199063

DOI: 10.1074/jbc.m402753200

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16815975

Title: HERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targets.

PubMed ID: 16815975

DOI: 10.1073/pnas.0600397103

PubMed ID: 18042542

Title: Induction of cell membrane protrusions by the N-terminal glutaredoxin domain of a rare splice variant of human thioredoxin reductase 1.

PubMed ID: 18042542

DOI: 10.1074/jbc.m708939200

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 17512005

Title: The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis.

PubMed ID: 17512005

DOI: 10.1016/j.jmb.2007.04.044

Sequence Information:

  • Length: 649
  • Mass: 70906
  • Checksum: 5A51C3F77EB03EFE
  • Sequence:
    • MGCAEGKAVA AAAPTELQTK GKNGDGRRRS AKDHHPGKTL PENPAGFTST ATADSRALLQ 
AYIDGHSVVI FSRSTCTRCT EVKKLFKSLC VPYFVLELDQ TEDGRALEGT LSELAAETDL 
PVVFVKQRKI GGHGPTLKAY QEGRLQKLLK MNGPEDLPKS YDYDLIIIGG GSGGLAAAKE 
AAQYGKKVMV LDFVTPTPLG TRWGLGGTCV NVGCIPKKLM HQAALLGQAL QDSRNYGWKV 
EETVKHDWDR MIEAVQNHIG SLNWGYRVAL REKKVVYENA YGQFIGPHRI KATNNKGKEK 
IYSAERFLIA TGERPRYLGI PGDKEYCISS DDLFSLPYCP GKTLVVGASY VALECAGFLA 
GIGLDVTVMV RSILLRGFDQ DMANKIGEHM EEHGIKFIRQ FVPIKVEQIE AGTPGRLRVV 
AQSTNSEEII EGEYNTVMLA IGRDACTRKI GLETVGVKIN EKTGKIPVTD EEQTNVPYIY 
AIGDILEDKV ELTPVAIQAG RLLAQRLYAG STVKCDYENV PTTVFTPLEY GACGLSEEKA 
VEKFGEENIE VYHSYFWPLE WTIPSRDNNK CYAKIICNTK DNERVVGFHV LGPNAGEVTQ 
GFAAALKCGL TKKQLDSTIG IHPVCAEVFT TLSVTKRSGA SILQAGCUG

Genular Protein ID: 2682623864

Symbol: B7Z2S5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z2S5

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 16 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 4 Gene3D 3 InterPro 8 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 3 PRINTS 2 PROSITE 2 PeptideAtlas 1 Pfam 4 ProteomicsDB 1 RefSeq 1 Rhea 6 RuleBase 1 SUPFAM 2

Sequence Information:

  • Length: 547
  • Mass: 60022
  • Checksum: FC83AE0AD905CD8C
  • Sequence:
    • MEDGRALEGT LSELAAETDL PVVFVKQRKI GGHGPTLKAY QEGRLQKLLK MNGPEDLPKS 
YDYDLIIIGG GSGGLAAAKE AAQYGKKVMV LDFVTPTPLG TRWGLGGTCV NVGCIPKKLM 
HQAALLGQAL QDSRNYGWKV EETVKHDWDR MIEAVQNHIG SLNWGYRVAL REKKVVYENA 
YGQFIGPHRI KATNNKGKEK IYSAERFLIA TGERPRYLGI PGDKEYCISS DDLFSLPYCP 
GKTLVVGASY VALECAGFLA GIGLDVTVMV RSILLRGFDQ DMANKIGEHM EEHGIKFIRQ 
FVPIKVEQIE AGTPGRLRVV AQSTNSEEII EGEYNTVMLA IGRDACTRKI GLETVGVKIN 
EKTGKIPVTD EEQTNVPYIY AIGDILEDKV ELTPVAIQAG RLLAQRLYAG STVKCDYENV 
PTTVFTPLEY GACGLSEEKA VEKFGEENIE VYHSYFWPLE WTIPSRDNNK CYAKIICNTK 
DNERVVGFHV LGPNAGEVTQ GFAAALKCGL TKKQLDSTIG IHPVCAEVFT TLSVTKRSGA 
SILQAGC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.